PhD position in Infection Biology
Sort on published: 2017-03-28
Uppsala University is a comprehensive research-intensive university with a strong international standing. Our mission is to pursue top-quality research and education and to interact constructively with society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has 42,000 students, 7,000 employees and a turnover of SEK 6.7 billion.
The Department of Medical Biochemistry and Microbiology (IMBIM) at Uppsala University constitutes a broad and international research and teaching environment with over 250 scientists, including over 40 PhD students. Research activities within the department focus on three principal domains: Biochemistry & Molecular Cell Biology, Genomics, and Microbiology & Immunology. The Sellin research group at IMBIM now seeks a motivated candidate with the ability to work independently and with a strong interest in pursuing a PhD degree in bacterial infection biology.
Project description: The Sellin research group studies interactions between invasive gut bacteria, such as Salmonella and Shigella species, and the mammalian intestinal epithelium (http://www.imbim.uu.se/Research/Microbiology-immunology/sellin-mikael/). Current research in the group employs infection studies in miniature cultured versions of the mammalian intestine (so called gut organoids), which can be generated by embedding intestinal stem cells in a rich 3D matrix. The PhD candidate will have an active role in further developing this experimental infection model system. Moreover, the candidate will use the model system to study i) the bacterial virulence factors and ii) host cell components that impact on each step of the bacterium – host cell interaction during a physiological infection. A particularly strong project focus lies in studies by advanced light microscopy techniques.
Duties: The successful candidate will engage in research work and doctoral studies. Other duties at the institution, i.e. administration and teaching, may be included in the employment up to a maximum level of 20 %. Salary is subject to established local guidelines.
Qualifications: For employment the candidate should hold a MSc degree or equivalent, with a strong course focus on cell biology and microbiology. Previous practical experience with mammalian cell culture methodology, especially primary cell culture, as well as light-microscopy-based analysis is highly desired. Experience with work on pathogenic microorganisms is a further merit. The candidate is expected to take own initiatives as well as collaborate with colleagues both within and outside of the group. Finally, significant weight will be given to personal suitability.
To be employed as a PhD student, the applicant must be accepted in the postgraduate programme. Information concerning doctoral education, requirements and rules of admission can be found http://www2.medfarm.uu.se/utbildning/forskarniva/. The length of the study period for full time employment is a maximum of four years. Terms for graduate studies can be found in Högskoleförordningen 5 kap §1-7.
Application: Please submit your application including i) a CV, ii) a letter describing your research interests, skills and motivation to apply for the position, iii) publications and/or a copy of master thesis or equivalent, together with iv) contact information of at least two referees (phone number and e-mail address) and v) a reference letter.
Pay: According to local agreement
Starting: As soon as possible
Working hours: 100 %
For further information about the position please contact
Dr. Mikael Sellin (firstname.lastname@example.org), +46 18 471 40 73
You are welcome to submit your application no later than May 5, 2017, UFV-PA 2017/1057.
We only accept the application the way described in the advertisement.
We decline offers of recruitment and advertising help. We only accept the application the way described in the advertisement.
Placement: Department of Medical Biochemistry and Microbiology
Type of employment: Full time , Temporary position longer than 6 months
Pay: Fixed pay
Number of positions: 1
Working hours: 100%
County: Uppsala län
Per Sundman, Saco-rådet
Marie Ols, TCO/ST 018-471 2459
Ellena Papaioannou, Seko 018-471 3315
Number of reference: UFV-PA 2017/1057
Last application date: 2017-05-05