PhD in Pharmacometrics
Sort on published: 2017-05-09
Uppsala University is a comprehensive research-intensive university with a strong international standing. Our mission is to pursue top-quality research and education and to interact constructively with society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has 40,000 students, 7,000 employees and a turnover of SEK 6.5 billion.
Uppsala Antibiotic Center (UAC) was announced in 2015 to bring together, stimulate and support research addressing important questions regarding antibiotic resistance from all three disciplinary domains at UU: Medicine and Pharmacy, Science and Technology and Humanities and Social sciences. UAC is now advertising 14 PhD positions.
Antibiotic resistance is a rapidly expanding global problem. The complexity of the current situation requires novel approaches in all scientific disciplines including new antibiotics, better understanding of resistance development, faster diagnostic methods, new economic models for drug development, global governance and better understanding of how to change behavior around the use of antibiotics and spread of pathogenic bacteria.
The present position is located at the Department of Pharmaceutical Biosciences. The Pharmaceutical Biosciences department at Uppsala University has a strong and international research and teaching environment with approximately 130 employees, including 50 PhD students, as well as a number of guest researchers and scholarship students. More information about the department and its activities is www.farmbio.uu.se
Project description: Model‐based design and analysis of clinical trials on drug therapies aimed to overcome antibiotic resistance. The PhD project will focus on advancing the analysis and design of clinical trials for evaluation of treatments against resistant bacteria, using pharmacokinetic-pharmacodynamic (PKPD) principles. For example, the understanding and quantification of outcomes can be supported by model-based analysis of several variables simultaneously and by incorporating PKPD information from preclinical studies. Drug combinations is a treatment strategy of increasing interest where modelling and simulation will be crucial to identify the dose regimens that are most informative to evaluate in a clinical trial. For general information about our research in Pharmacometrics: http://www.farmbio.uu.se/research/researchgroups/pharmacometrics/
Duties We seek a highly-motivated individual, with the ability to work independently and a strong interest in pursuing a PhD degree in Pharmaceutical Sciences. The holder of a PhD student position must primarily concentrate on his/her own research studies. Other departmental work including teaching and administrative work can be part of the position (maximum 20%). Provisions for students are contained in the Higher Education Ordinance (Högskoleförordningen) chapter 5, sections 1-7.
Requirements: Applicants must have, or soon be expected to have, graduated from basic training in the appropriate area. The applicant should have a strong focus and clear interest in relevant areas such as pharmacokinetics, pharmacodynamics, statistics and/or mathematical modelling. Completion of courses related to this area as well as experience of pharmacometric analysis of pharmacokinetic and/or pharmacodynamic data is qualifying, as well as experience of design and analysis of clinical trials. The candidate is expected to take own initiatives as well as to collaborate with colleagues both within and outside of the group. Finally, significant weight will be given to personal suitability.
Information about doctoral education, qualification requirements and admission arrangements can be found at http://www2.medfarm.uu.se/utbildning/forskarniva/. Selection of candidates will be made by the supervisor in consultation with the department’s research education group. The Medicine and Pharmacy Research Education Committee is the body that formally accepts the student.
The length of the study period for full time employment is a maximum of four years. Terms for graduate studies can be found in Högskoleförordningen 5 kap 1-7 §§. Salary is subject to established local guidelines.
Application: Rules governing Ph.D. candidates are set out in the Higher Education Ordinance Chapter 5, §§ 1-7 and in Uppsala university's rules and guidelines http://regler.uu.se/Rules_and_regulations_in_English/
Please only submit your application using the Uppsala University Job portal. Please submit your application including (i) a CV, (ii) a letter describing your research interests, skills and motivation to apply for the position, (iii) publications and/or a copy of master thesis together with (iv) two reference letters.
Uppsala University strives to be an inclusive workplace that promotes equal opportunities and attracts qualified candidates who can contribute to the University’s excellence and diversity. We welcome applications from all sections of the community and from people of all backgrounds.
Pay: According to local agreement for PhD students and teaching assistants.
Starting: 2017-09-01 or as otherwise agreed, temporary position
Working hours: 100 %
For further information about the position please contact
professor Lena Friberg, email@example.com
You are welcome to submit your application no later than 2017-06-15, UFV-PA 2017/1574.
Are you considering moving to Sweden to work at Uppsala University? If so, you will find much information about working and living in Sweden at www.uu.se/joinus. You are also welcome to contact the International Faculty and Staff Services at firstname.lastname@example.org.
We decline offers of recruitment and advertising help. We only accept the application the way described in the advertisement.
Type of employment: Full time , Temporary position longer than 6 months
Pay: Fixed pay
Number of positions: 1
Working hours: 100 %
County: Uppsala län
Per Sundman, Saco-rådet
Ellena Papaioannou, Seko 018-471 3315
Suzanne Borén Andersson, TCO/ST 018-471 6251
Number of reference: UFV-PA 2017/1574
Last application date: 2017-06-15