Postdoctoral fellow in Medical Genetics
Sort on published: 2018-07-02
Uppsala University is a comprehensive research-intensive university with a strong international standing. Our mission is to pursue top-quality research and education and to interact constructively with society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has 42,000 students, 7,000 employees and a turnover of SEK 6.7 billion.
The Department of Immunology, Genetics and Pathology at Uppsala University (www.igp.uu.se) has a broad research profile with strong research groups focused on cancer, autoimmune and genetic diseases. A fundamental idea at the department is to stimulate translational research and thereby closer interactions between medical research and health care. Research is presently conducted in the following areas: medical and clinical genetics, clinical immunology, pathology, neuro-oncology, vascular biology, radiation science and molecular tools. Department activities are also integrated with the units for Oncology, Clinical Genetics, Clinical Immunology, Clinical Pathology, and Hospital Physics at Akademiska sjukhuset, Uppsala. The department has teaching assignments in several education programmes, including Master Programmes, at the Faculty of Medicine, and in a number of educations at the Disciplinary Domain of Science and Technology. The department has a yearly turnover of around SEK 400 million, out of which more than half is made up of external funding. The staff amounts to approximately 340 employees, out of which 100 are PhD-students, and there are in total more than 600 affiliated people.
SciLifeLab (www.scilifelab.se) is a Swedish national center for molecular biosciences with focus on health and environmental research. The center combines frontline technical expertise with advanced knowledge of translational medicine and molecular bioscience. SciLifeLab is hosted by four Swedish universities (Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University) and collaborates with several other universities.
SciLifeLab invites applications for Postdoc positions in the groups of our SciLifeLab Faculty.
The main duty is to establish the technology to isolate cell nuclei in order to measure gene activity in individual nuclei. Different techniques will be tested and they include tissue homogenization, enrichment of nuclei using centrifugation through different media and sorting using FACS. Nuclei will be isolated from metabolically active tissues including liver, muscle, fat and Langerhans islets. Gene activity will be measured using large-scale DNA sequencing och will be performed in collaboration wioth the SNP&SEQ facility at NGI/SciLifeLab in Uppsala. The project also includes computerbased analyses of results using both establishes software and programs which will be developed in the project. The results will be integrated with other large-scale data sets of metabolites et cetera in the same samples.
PhD in experimental/bioinformatics science. To be eligible to apply you must have a PhD completed within three years of the application deadline. If you received your PhD earlier but special circumstances exist you are also eligible to apply. Knowledge of how to isolate cell nuclei and previous work with metabolically active tissues like liver, muscle, fat and insulin-producing cells is a good qualification. Experience of work to analyze the results of “next generation DNA sequencing” is also an important merit, as well as development of new pipelines for large-scale data analysis.
The project is interdisciplinary so good knowledge of modern human genetics and good collaborative skills are required.
Uppsala University values the qualities that even gender distribution and diversity add to the business. We therefore look forward to searching for all sexes and with different birth background, functionality and life experience.
Salary: According to individual qualifications
Start date: as soon as possible
Form of employment: general temporary employment of two years
Extent of employment: 100%
For more information contact:
Claes Wadelius, 018-471 4076, firstname.lastname@example.org
You are welcome to apply no later than July 16, 2018. UFV-PA 2018/2365.
Please do not send offers of recruitment or advertising services. Applications must be submitted as described in this advertisement.
Placement: Department of Immunology, Genetics and Pathology
Type of employment: Full time , Temporary position longer than 6 months
Pay: Fixed pay
Number of positions: 1
Working hours: 100%
County: Uppsala län
Ellena Papaioannou, Seko
Suzanne Borén Andersson, TCO/ST 018-471 6251
Per Sundman, Saco-rådet 018-471 1485
Number of reference: UFV-PA 2018/2365
Last application date: 2018-07-16