Postdoctoral fellow in preclinical brain cancer therapy
Sort on published: 2018-10-29
Uppsala University is a comprehensive research-intensive university with a strong international standing. Our mission is to pursue top-quality research and education and to interact constructively with society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has 42,000 students, 7,000 employees and a turnover of SEK 6.7 billion.
The Department of Immunology, Genetics and Pathology at Uppsala University (www.igp.uu.se) has a broad research profile with strong research groups focused on cancer, autoimmune and genetic diseases. A fundamental idea at the department is to stimulate translational research and thereby closer interactions between medical research and health care. Research is presently conducted in the following areas: medical and clinical genetics, clinical immunology, pathology, neuro-oncology, vascular biology, radiation science and molecular tools. Department activities are also integrated with the units for Oncology, Clinical Genetics, Clinical Immunology, Clinical Pathology, and Hospital Physics at Akademiska sjukhuset, Uppsala. The department has teaching assignments in several education programmes, including Master Programmes, at the Faculty of Medicine, and in a number of educations at the Disciplinary Domain of Science and Technology. The department has a yearly turnover of around SEK 400 million, out of which more than half is made up of external funding. The staff amounts to approximately 340 employees, out of which 100 are PhD-students, and there are in total more than 600 affiliated people.
SciLifeLab (www.scilifelab.se) is a Swedish national center for molecular biosciences with focus on health and environmental research. The center combines frontline technical expertise with advanced knowledge of translational medicine and molecular bioscience. SciLifeLab is hosted by four Swedish universities (Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University) and collaborates with several other universities. SciLifeLab invites applications for Postdoc positions in the groups of our SciLifeLab Faculty.
Work description: We are seeking a motivated Postdoc for experimental laboratory work in a cross-disciplinary team focused on childhood brain tumor biology and studies of future treatment options for cancer recurrences. The duties involve: (1) Identifying novel cancer drugs that can sensitize brain tumor cells for standard irradiation treatment (2) Study the mechanism for recurrence in various in vivo models for malignant brain tumors. (3) Study novel targeted cancer treatments in combination with advanced image-guided irradiation therapy in vivo.
The project involves setting up drug screens to study efficacy of various substances. It also involves using advanced laboratory techniques including stem cell culturing, cell sorting, immunostainings, confocal microscopy, irradiation treatment, lentiviral production, gene cloning and editing, in vivo models, treatment studies and drug screening. The project aims at improving targeted therapies against childhood brain cancer. Finally, some of the work in the position involves administration and teaching (max 20 %) at the department.
Qualifications: A PhD in biomedicine, pharmacy, medicine or a similar field of research. To be eligible to apply you must have a PhD completed within three years of the application deadline. If you received your PhD earlier but special circumstances exist, you are also eligible to apply. Documented experience of work with in vivo models (FELASA C certificate or similar), drug screening and cell based assays. Documented experience in working in cross-disciplinary teams that bridge molecular biology or experimental research with translational/ clinical research and bioinformatics.
Merits: Experience of radiation therapy or high-throughput studies, e.g. drug screening. Experience from neuroscience or brain tumor research.
Application: Your application should comprise a CV, copies of degrees and relevant study transcripts and grades, publications and a short description of your research interests. We request that you provide references and provide at least one letter of recommendation. The applications are assessed according to these criteria: qualifications as above, basic training, prior experience in related areas. Great emphasis is placed on personal suitability.
Uppsala University strives to be an inclusive workplace that promotes equal opportunities and attracts qualified candidates who can contribute to the University’s excellence and diversity. We welcome applications from all sections of the community and from people of all backgrounds.
Salary: According to individual qualifications.
Start date: As soon as possible.
Form of employment: General temporary employment of two years.
Extent of employment: 100 %.
For more information contact: Fredrik Swartling, 018-471 4868, firstname.lastname@example.org.
You are welcome to apply no later than December 9, 2018, UFV-PA 2018/3561.
Are you considering moving to Sweden to work at Uppsala University? If so, you will find much information about working and living in Sweden at www.uu.se/joinus. You are also welcome to contact the International Faculty and Staff Services at email@example.com.
We decline offers of recruitment and advertising help. We only accept the application the way described in the advertisement.
Placement: Department of Immunology, Genetics and Pathology
Type of employment: Full time , Temporary position longer than 6 months
Pay: fixed pay
Number of positions: 1
Working hours: 100 %
County: Uppsala län
Ellena Papaioannou, Seko
Suzanne Borén Andersson, TCO/ST 018-471 6251
Per Sundman, Saco-rådet 018-471 1485
Number of reference: UFV-PA 2018/3561
Last application date: 2018-12-09