Early Stage Researcher (ESR#5) PhD fellowship in the Marie Skłodowska-Curie ITN European Training Network TREATMENT: "Metabolic Dysfunctions associated with Pharmacological Treatment of Schizophrenia
Sort on published: 2018-12-21
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Early Stage Researcher (ESR#5) PhD fellowship in the Marie Skłodowska-Curie ITN European Training Network TREATMENT: "Metabolic Dysfunctions associated with Pharmacological Treatment of Schizophrenia" | EURAXESS
ESR5 will study direct and indirect effects of the antipsychotic drugs on human adipose tissue insulin signalling, glucose and lipid metabolism.
The ESR will engage in in-vitro as well as clinical studies that will: i) Investigate the effects on glucose uptake in human adipose cells and its interactions with insulin signalling. ii) Elucidate the effects on lipolysis, lipid storage and the expression genes regulating lipid metabolism (including fatty acid synthesis and storage as well as oxidation).
The ESR will analyse alterations in insulin-stimulated glucose uptake, insulin signalling and lipid handling that may contribute to the development of insulin resistance following antipsychotic drug treatment. These may contribute to lipid deposition in other organs, such as liver and muscle, leading to dyslipidemia. These studies will provide biomarkers and mechanisms relating to drug-induced metabolic dysfunction at the level of adipose tissue as well as the whole body.
Host: Uppsala Universitet (Uppsala, Sweden)
Uppsala University strives to be an inclusive workplace that promotes equal opportunities and attracts qualified candidates who can contribute to the University’s excellence and diversity. We welcome applications from all sections of the community and from people of all backgrounds.
Additional information and how to submit your application: https://euraxess.ec.europa.eu/jobs/361904
Please submit your application by 15 January 2019, UFV-PA 2018/4743.
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Placement: Department of Medical Sciences
Type of employment: Full time , PhD placement
Number of positions: 1
Working hours: 100%
County: Uppsala län
Ellena Papaioannou, Seko
Suzanne Borén Andersson, TCO/ST 018-471 6251
Per Sundman, Saco-rådet 018-471 1485
Number of reference: UFV-PA 2018/4743
Last application date: 2019-01-15