After having completed the course the students should be able to:
account for structure and function of infectious viruses, bacteria, parasites and fungi and explain the differences between groups of infectious organisms
explain a general infection process and list the different stages
account for the most important components of the human immune system and for the components that are important in various types of infections
describe the most common virulence factors in bacteria, viruses, parasites and worms and explain how they have evolved and how they can be transmitted
account for the most common diagnostic methods and treatments within infection biology and for the mechanisms of antibiotic resistance
practice adequate methodology for work with infectious microorganisms
analyse infection biological research data, draw conclusions, and propose testable hypotheses from the analysed data
review critically scientific papers in the field
identify and in a structured way discuss aspects related to research ethics, public health ethics, and global justice.
Bacteriology: The fundamental structure of bacteria, especially structures and mechanisms important for pathogenicity and virulence. Virology: Components and structures of viral particles and the basis of virus classification. Parasitology and mycology: General and specific properties of infectious protozoa, worms and fungi. Immunology: Adaptive and innate immunity. Virulence factors: Description of the most common virulence mechanisms. Diagnostics and vaccination: Basal principles for diagnosis and vaccination. The basis for PCR, RT-PCR, immunofluorecsence, ELISA, FACS and Western blotting. Antibiotics and antibiotics resistance: Principles of antibiotic mechanisms. Mechanisms of the origin of antibiotics resistance.
- Studies of modes of action of antibiotics. - Diagnostics of parasitic diseases. - Studies of host parasite interactions.
Reading and critical examination of current scientific articles within infection biology. Teacher-supervised group discussions.
Teaching includes lectures, seminars and laboratory practicals. Participation in seminars and practicals is compulsory.
Modules: Laboratory practicals and seminars 4 credits; Theory I, 5 credits; Theory II, 6 credits.
Practicals and seminars require active participation. The theory is examined trough two written exams: an examination of more detailed knowledge after the first part of the course (Theory I) and a comprehensive examination (Theory II) at the end of the course.
week 30, 2015
Schaechter's mechanisms of microbial disease
Engleberg, N. Cary.;
DiRita, Victor J.;
Wolters Kluwer Health/Lippincott Williams & Wilkins,