The successful participant of this course will have the ability to:
Present and discuss advanced methods in organic synthesis
Find relevant information from the literature by database searching
Apply various synthesis tools to organic compounds with low molecular weight.
Describe and plan DOS (diversity-oriented synthesis)
Present, discuss, plan and execute the construction and evaluation of a low-molecular-weight compound library.
Tools for synthesis planning, such as retrosynthesis, DOS and high-throughput strategies and their application in organic synthesis. Reactivity and selectivity in organic-chemical transformations, and their importance in synthesis planning.
Individual design project, which includes the planning of the synthesis, literature search, a presentation, as well as experimental work to prepare the suggested molecules.
Training in communication skills with written report, oral presentation, feed-back and opposition.
The teaching will be conducted by lectures, and practical work in the laboratory and theoretical exercises and projects. A significant part of the course takes place in the form of projects, where students work both individually and in groups.
A written exam will be given in the end of the course (10 credits). Reports are assessed by written and oral presentation with opposition. The mandatory exercises and reports correspond to 5 credits. The final grade is based on both the written exam and the mandatory exercises.