Master’s studies

Syllabus for Chemical Libraries and Efficient Synthesis

Kemiska bibliotek och effektiv syntes

Syllabus

  • 15 credits
  • Course code: 1KB455
  • Education cycle: Second cycle
  • Main field(s) of study and in-depth level: Chemistry A1N
  • Grading system: Fail (U), 3, 4, 5.
  • Established: 2008-03-13
  • Established by: The Faculty Board of Science and Technology
  • Revised: 2014-04-23
  • Revised by: The Faculty Board of Science and Technology
  • Applies from: week 30, 2014
  • Entry requirements: 120 credits with 60 credits in chemistry.
  • Responsible department: Department of Chemistry - BMC

Learning outcomes

The successful participant of this course will have the ability to:

  • Present and discuss advanced methods in organic synthesis
  • Find relevant information from the literature by database searching
  • Apply various synthesis tools to organic compounds with low molecular weight.
  • Describe and plan DOS (diversity-oriented synthesis)
  • Present, discuss, plan and execute the construction and evaluation of a low-molecular-weight compound library.

Content

Tools for synthesis planning, such as retrosynthesis, DOS and high-throughput strategies and their application in organic synthesis. Reactivity and selectivity in organic-chemical transformations, and their importance in synthesis planning.

Individual design project, which includes the planning of the synthesis, literature search, a presentation, as well as experimental work to prepare the suggested molecules.

Training in communication skills with written report, oral presentation, feed-back and opposition.

Instruction

The teaching will be conducted by lectures, and practical work in the laboratory and theoretical exercises and projects. A significant part of the course takes place in the form of projects, where students work both individually and in groups.

Assessment

A written exam will be given in the end of the course (10 credits). Reports are assessed by written and oral presentation with opposition. The mandatory exercises and reports correspond to 5 credits. The final grade is based on both the written exam and the mandatory exercises.

Reading list

Applies from: week 30, 2014

  • Wyatt, Paul Warren, Stuart G. Organic synthesis : strategy and control

    Chichester: John Wiley, cop. 2007

    Find in the library