Master Programme in Molecular Medicine 2014/2015
In this programme you will learn about molecular mechanisms that cause diseases, the newest technologies in genomics, epigenetics and proteomics as well as development of prognostic, diagnostic and therapeutic tools, a crucial aspect of tomorrow’s health care offering personalized and improved translational medicine. You will be in an advanced educational environment at the research frontiers of molecular medicine, with researchers, clinicians and industry from world-
leading laboratories at Uppsala University.
About the programme
The programme gives you in-depth knowledge about molecular and cellular mechanisms causing diseases, including genetic diseases and cancer, with special emphasis on epigenetic mechanisms. You will learn to independently analyse and interpret research results and data, generated by current methods and technologies. You will also learn techniques for developing novel molecular diagnostics and therapies with applications in both research and industry.
During the first year, you will focus on methods and technologies for assessing genetic as well as epigenetic variations, current clinical diagnostics and novel approaches to treatment. You will study in depth research-oriented problems in molecular medicine and be trained in experimental design and laboratory work. We describe the use and applications of new sequencing technologies and data analysis with an emphasis on genome analysis, epigenomics and comparative genomics as well as current methods in proteomics, analysis of proteins and protein expression with identification of novel biomarkers for diseases, using practical applications within the Human Proteome project (HPR). In the laboratory, you will for example study epigenetic changes in cancer cells using pyrosequencing and ChIP analysis as well as perform diagnostic analysis by proximity ligation assay (PLA). The programme will also give you insights into project planning, presentation techniques and research ethics. If you are interested in research and in gaining laboratory experience, you can apply for parallel projects.
The second year includes analysis and diagnostics by molecular imaging, from the detection of single nucleotide polymorphisms to whole body analysis. The course Regenerative Medicine describes stem cells therapies, tissue engineering, generation of biomaterials as well as other novel cell and immunotherapies against human diseases. In the laboratory, you will perform in vitro differentiation of neuronal and myeloid stem cells. The last semester, you will undertake an independent degree project in molecular medicine in a research group at an academic department, in a company or other agency in Sweden or abroad. You conclude the degree project by writing a thesis, compiling the research results, and giving a research seminar.
The programme leads to a Master of Medical Science (120 credits) with Molecular Medicine as the main field of study.
The teaching includes lectures, seminars, web-based exercises, demonstrations, project work as well as theoretical and practical tasks. The lectures provides you with an understanding of current research and perspectives, and are given by scientists specialized in the field. During seminars, we will discuss experimental methods, strategies and research results, while reviewing the scientific literature. The programme and teaching are tightly linked to on-going medical and technological research, offering a solid basis for future work either in academia or in industry. You will interact with researchers and clinicians from Uppsala University and Uppsala University Hospital, providing an advanced education, closely connected with local biotechnology companies and the drug industry.
You will independently compile and present research findings, both in writing and orally. Apart from training in independent thinking and analysis, you will early on obtain direct insights into on-going research. You will gain practical experiences of current methods in genomics, epigenomics and proteomics. You will be part of a dynamic academic research environment with access to expertise and state-of-the-art technologies. Your achievements during seminars and laboratory work will be evaluated together with your ability to analyse, interpret and present research results, both in writing and orally as well as together with your theoretical knowledge, assessed by examinations and seminars. The programme is taught entirely in English.
Courses within the programme
Medical genetics and cancer; molecular mechanisms, 15 credits
Advanced techniques in molecular medicine, 15 credits
Genomic and Epigenomic medicine, 15 credits
Molecular tools for Proteome Analysis and Diagnostics, 7.5 credits
Biomarkers; discovery and validation, 7.5 credits
Bioimaging and Cell analysis, 7.5 credits
Regenerative medicine, 7.5 credits
Elective period, 15 credits
Master project in molecular medicine, 30/45 credits
With an advanced education in molecular medicine you are expected to go on to occupations in research, health-care systems, pharma or biotechnology companies, and governmental organisations.
The strong component of cutting-edge research in the programme gives you an excellent basis for further academic research and PhD studies in the field. You will have gained practical experience of several new molecular technologies and their applications for research in genomics, epigenomics and proteomics, which together with a profound understanding of molecular mechanisms in diseases including cancer, is a requisite for progress in medical research as well as in health care.