Biomarkers, Discovery and Validation

7.5 credits

Course, Master's level, 3MG028

Spring 2024 Spring 2024, Uppsala, 100%, On-campus, English

Spring 2024 Spring 2024, Uppsala, 100%, On-campus, English For exchange students

Spring 2025 Spring 2025, Uppsala, 100%, On-campus, English

Spring 2025 Spring 2025, Uppsala, 100%, On-campus, English For exchange students

About the course

The course provides an insight into the current knowledge, future potential use and development of biomarkers as both prognostic and diagnostic tools in health care. Different types of biomarkers will be discussed as well as the methods for the discovery and validation of protein biomarkers in serum. Biomarkers for different diseases will be treated, such as biomarkers for cancers, and neurological and cardiovascular diseases. Biomarkers in disease epidemiology and pathology will be covered. Biobanking and ethical considerations will be discussed and current clinical methods and diagnostics will be illustrated. Current opinions and research findings of molecular biomarkers, as well as the development of novel methods and technologies, will be discussed. The Human Protein Atlas will be described and used in practical exercises, illustrating the discovery of biomarkers for different cancers and other diseases.

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