Syllabus for Proteomics and Metabolomics

Proteomik och metabolomik

Syllabus

  • 5 credits
  • Course code: 1KB162
  • Education cycle: Second cycle
  • Main field(s) of study and in-depth level: Technology A1N, Bioinformatics A1N, Chemistry A1N

    Explanation of codes

    The code indicates the education cycle and in-depth level of the course in relation to other courses within the same main field of study according to the requirements for general degrees:

    First cycle
    G1N: has only upper-secondary level entry requirements
    G1F: has less than 60 credits in first-cycle course/s as entry requirements
    G1E: contains specially designed degree project for Higher Education Diploma
    G2F: has at least 60 credits in first-cycle course/s as entry requirements
    G2E: has at least 60 credits in first-cycle course/s as entry requirements, contains degree project for Bachelor of Arts/Bachelor of Science
    GXX: in-depth level of the course cannot be classified.

    Second cycle
    A1N: has only first-cycle course/s as entry requirements
    A1F: has second-cycle course/s as entry requirements
    A1E: contains degree project for Master of Arts/Master of Science (60 credits)
    A2E: contains degree project for Master of Arts/Master of Science (120 credits)
    AXX: in-depth level of the course cannot be classified.

  • Grading system: Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
  • Established: 2019-03-05
  • Established by: The Faculty Board of Science and Technology
  • Applies from: week 30, 2019
  • Entry requirements: Alt 1. 120 credits within the Master Programme in Molecular Biotechnology Engineering, including Biotechnical Methodology, Genomics and Bioinformatics, and Multivariate Data Analysis and Experimental Design. 
    English language proficiency that corresponds to English studies at upper secondary (high school) level in Sweden ("English 6").
    Alt 2. 120 credits including Introduction to Bioinformatics and Introduction to Programming, Scientific Computing and Statistics.
    English language proficiency that corresponds to English studies at upper secondary (high school) level in Sweden ("English 6").
    Alt 3. 120 credits including Introduction to Bioinformatics and Introduction to Molecular Biology, Genetics and Evolution.
    English language proficiency that corresponds to English studies at upper secondary (high school) level in Sweden ("English 6").
  • Responsible department: Department of Chemistry - BMC

Learning outcomes

On completion of the course, the student should be able to:

  • account for and compare methods to study proteomics and metabolomics
  • motivate the choice of methods and carry out basic experimental design for given biological and biomedical problems.
  • carry out raw data analysis on collected data, such as identification of peptides / proteins / metabolites and comparison of proteomes and metabolomes between different groups of samples
  • account for applications of proteomics and metabolomics in medicine and biology

Content

Introduction to proteomics and metabolomics. Methodologies and associated strategies for raw data analysis aimed at studying proteomics, especially mass spectrometry and antibody-based methods. Measurement methods with associated methods for raw data analysis designed to study the metabolome, especially mass spectrometry and NMR spectroscopy. Basic experimental design and strategies for comparative proteomics and metabolomics. Public database resources for data evaluation and interpretation of results. Examples of applications in medicine and biology.

Instruction

Lectures, seminars and computer labs.

Assessment

Written examination (3 credits), seminars and computer labs (2 credits). The final grade corresponds to a weighted average of the results of the different components of the course.

If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the disability coordinator of the university.

Other directives

Cannot be included in a degree together with Proteomik och metabolomik, 5 hp (1MB448).

Reading list

Reading list

Applies from: week 35, 2019

Scientific articles