Syllabus for Introduction to Molecular Biology, Genetics and Evolution

Introduktion till molekylärbiologi, genetik och evolution

Syllabus

  • 15 credits
  • Course code: 1MB439
  • Education cycle: First cycle
  • Main field(s) of study and in-depth level: Biology G2F

    Explanation of codes

    The code indicates the education cycle and in-depth level of the course in relation to other courses within the same main field of study according to the requirements for general degrees:

    First cycle
    G1N: has only upper-secondary level entry requirements
    G1F: has less than 60 credits in first-cycle course/s as entry requirements
    G1E: contains specially designed degree project for Higher Education Diploma
    G2F: has at least 60 credits in first-cycle course/s as entry requirements
    G2E: has at least 60 credits in first-cycle course/s as entry requirements, contains degree project for Bachelor of Arts/Bachelor of Science
    GXX: in-depth level of the course cannot be classified.

    Second cycle
    A1N: has only first-cycle course/s as entry requirements
    A1F: has second-cycle course/s as entry requirements
    A1E: contains degree project for Master of Arts/Master of Science (60 credits)
    A2E: contains degree project for Master of Arts/Master of Science (120 credits)
    AXX: in-depth level of the course cannot be classified.

  • Grading system: Fail (U), Pass (G)
  • Established: 2018-03-06
  • Established by:
  • Revised: 2019-02-08
  • Revised by: The Faculty Board of Science and Technology
  • Applies from: week 27, 2019
  • Entry requirements: A Bachelor's degree, equivalent to a Swedish Kandidatexamen, from an internationally recognised university. Also required is 30 credits in mathematics and 30 credits in computer science.
  • Responsible department: Biology Education Centre

Learning outcomes

On completion of the course, the student should be able to:

  • account for the structure and function of biomolecules and macromolecules
  • describe the structure and organisation of genomes, the transfer of genetic information, sources of genetic variation and their consequences for fitness 
  • describe cell structure and regulation in prokaryotic and eukaryotic cells
  • describe the cell cycle, metabolism and principles of energy production within cells 
  • account for a number of modern molecular biology methods for molecular and genetic problems 
  • describe the evolutionary processes and mechanisms shaping genomes in natural populations
  • describe the diversity of life and how this diversity is organized
  • interpret phylogenetic trees 
  • read and critically evaluate scientific journal articles and discuss scientific, societal and ethical aspects of gene technology.

Content

Basic life chemistry: chemical bonds and biomolecules. The molecular basis of transmission of genetic information from genes to proteins: DNA replication, DNA repair, recombination, transposition, transcription, translation, and gene regulation. Genomes and their structure: chromosomes, plasmids, plastids and mitochondria. Inheritance/transfer of genetic information: meiosis, sexual reproduction, classical genetics and extrachromosomal inheritance and genetic transfer in bacteria and viruses. Genome evolution: sources for variation - mutations and recombination, and effects of natural selection on genome evolution over time. Cell structure, diversity and communication. Energy production and the chemical processes within cells: respiration, photosynthesis, and metabolism. The different forms of life from an organismal and evolutionary points of view. Gene trees and species trees and homology. Variation between genomes, its causes and consequences. Gene technology: introduction to modern technologies, e.g. restriction mapping, cloning, gene expression to overproduce proteins of interest, DNA-sequencing, PCR, and societal and ethical considerations. Evaluating the strengths and limitations of data: critical evaluation of experimental data and scientific literature.

Instruction

Lectures, computer laborations, seminars and demonstrations.

Assessment

Molecular biology and genetics:  Two written tests (4 hp each) and practical parts (active participation in seminars and presentation of seminar assignments) (2 hp). Evolution: Written test (3 hp), active participation in seminars (1 hp) and computer laboration reports (1 hp).

If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the disability coordinator of the university.

Reading list

Reading list

Applies from: week 27, 2019

  • Campbell, Neil A. Biology : a global approach

    11. ed., Global ed.: Harlow: Pearson Education Ltd., [2017]

    Find in the library