Syllabus for Immunotechnology

Immunteknik

  • 10 credits
  • Course code: 1MB463
  • Education cycle: Second cycle
  • Main field(s) of study and in-depth level: Technology A1N, Applied Biotechnology A1N

    Explanation of codes

    The code indicates the education cycle and in-depth level of the course in relation to other courses within the same main field of study according to the requirements for general degrees:

    First cycle
    G1N: has only upper-secondary level entry requirements
    G1F: has less than 60 credits in first-cycle course/s as entry requirements
    G1E: contains specially designed degree project for Higher Education Diploma
    G2F: has at least 60 credits in first-cycle course/s as entry requirements
    G2E: has at least 60 credits in first-cycle course/s as entry requirements, contains degree project for Bachelor of Arts/Bachelor of Science
    GXX: in-depth level of the course cannot be classified.

    Second cycle
    A1N: has only first-cycle course/s as entry requirements
    A1F: has second-cycle course/s as entry requirements
    A1E: contains degree project for Master of Arts/Master of Science (60 credits)
    A2E: contains degree project for Master of Arts/Master of Science (120 credits)
    AXX: in-depth level of the course cannot be classified.

  • Grading system: Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
  • Established: 2017-03-09
  • Established by:
  • Revised: 2021-03-26
  • Revised by: The Faculty Board of Science and Technology
  • Applies from: week 27, 2022
  • Entry requirements: Alt . 1) 120 credits in the engineering programme in molecular biotechnology including cell biology and biotechnical methodology.
    Alt . 2) 120 credits. The overview trends in molecular biology and biotechnology. Proficiency in English equivalent to the Swedish upper secondary course English 6.
  • Responsible department: Biology Education Centre

Learning outcomes

On completion of the course, the student should be able to:

  • account for the structure and function at the molecular and cellular level of the immune defence
  • account for polyclonal, monoclonal and humanized antibodies and production of these
  • describe immunization/vaccination, immunological disease and immunotherapy
  • plan, carry out and present achieved results of immunological serum analyses by means of enzyme coupled immune adsorbent analysis (ELISA)
  • discuss immunological techniques and their applications in biotechnical industry.

Content

The innate and adaptive immune defence and its components. Cells and molecules that participate in these systems and their roles in combating infectious agents. Activation of these defence systems. The genetic mechanisms that control the formation of the specific receptors against foreign subjects in the form of antibodies and T cell receptors.

The use of antibodies in biotechnical applications such as ELISA, ELISpot, immunohistochemistry, western blot, flow cytometry, cell isolation with MACS, multiplex bead array, proximity ligation assay. Technologies for production of antibodies and isolation/purifying with protein A as well as immunological tests based on cellular reactions. Use of Biacore for determination of bond strengths in antibody-antigen interactions and use of structure data to understand and modulate immunological molecules. Immunological diseases as allergy, autoimmunity and immune deficiencies as well as the technologies that are used for diagnosis and treatment of these diseases as well as cancer.

Practical laboratory session that handles production and test of polyclonal antibodies. Theoretical exercises that cover different topics within immunology. Projects with a specialization in immunological technology. Study visits at companies that use immunological techniques.

Instruction

Lectures, laboratory sessions, exercises, study visits, seminars and projects.

Assessment

Written examination (5 credits). Laboratory sessions (3 credits), theoretical exercises (1 credit) and oral presentation of project (1 credit).

If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the disability coordinator of the university.

Reading list

The reading list is missing. For further information, please contact the responsible department.