Syllabus for Molecular Biology and Genetics II

Molekylärbiologi och genetik II

A revised version of the syllabus is available.

Syllabus

  • 15 credits
  • Course code: 1BG230
  • Education cycle: First cycle
  • Main field(s) of study and in-depth level: Biology G2F

    Explanation of codes

    The code indicates the education cycle and in-depth level of the course in relation to other courses within the same main field of study according to the requirements for general degrees:

    First cycle

    • G1N: has only upper-secondary level entry requirements
    • G1F: has less than 60 credits in first-cycle course/s as entry requirements
    • G1E: contains specially designed degree project for Higher Education Diploma
    • G2F: has at least 60 credits in first-cycle course/s as entry requirements
    • G2E: has at least 60 credits in first-cycle course/s as entry requirements, contains degree project for Bachelor of Arts/Bachelor of Science
    • GXX: in-depth level of the course cannot be classified

    Second cycle

    • A1N: has only first-cycle course/s as entry requirements
    • A1F: has second-cycle course/s as entry requirements
    • A1E: contains degree project for Master of Arts/Master of Science (60 credits)
    • A2E: contains degree project for Master of Arts/Master of Science (120 credits)
    • AXX: in-depth level of the course cannot be classified

  • Grading system: Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
  • Established: 2015-03-12
  • Established by: The Faculty Board of Science and Technology
  • Revised: 2016-04-25
  • Revised by: The Faculty Board of Science and Technology
  • Applies from: week 27, 2016
  • Entry requirements: 80 credits in biology equivalent to the basic course in biology within the Bachelor Programme in Biology/Molecular Biology.
  • Responsible department: Biology Education Centre

Learning outcomes

After passing the course the student should be able to

  • describe thoroughly how gene expression is regulated in bacteria, archaea and eukaryotes
  • independently use and optimise basic molecular tools such as PCR and cloning
  • use some and describe several methods and strategies for deeper analysis of biological questions, e.g. gene inactivation, fluorescent reporter genes and model organisms
  • describe how advanced molecular tools such as large-scale sequencing and proteomics can be used to study gene expression
  • describe genetic applications such as evolutionary genetics, disease genetics and forensic genetics
  • read and evaluate scientific articles and suggest follow-up experiments
  • describe ethical issues related to the subjects that are covered during the course

Content

The course focuses on regulation of gene expression in bacteria, archaea and eukaryotes, and basic molecular biological and genetic methods as well as the latest large-scale methods that are used to study gene function and gene expression. The following subjects are covered during the course: Repetition of basic molecular biology and genetics; Epigenetics; Post-transcriptional regulation mediated by small and large RNA molecules; Translational control. The latest methods within analysis of gene expression, e.g. large-scale sequencing and proteomics. Applied genetics: Evolutionary genetics, disease genetics and forensic genetics. Methods for further studies of gene function: inactivation of genes, reporter genes, model organisms. Experimental strategies: selection of methods to study a specific scientific problem. Practical training in PCR, cloning, epigenetics in fission yeast and inactivation of gene expressions by means of RNA-interference in the roundworm C. elegans. Ethical questions within molecular biology and genetics. Study visits at e.g. SciLifeLab.

Instruction

Lectures, laboratory sessions, seminars and study visits.

Assessment

Theory 9 credits (written examination), laboratory sessions 5 credits (attendance and written and oral presentation), seminar 1 credit (attendance in seminars and oras as well as written presentation for literature seminar).

Syllabus Revisions

Reading list

Reading list

Applies from: week 27, 2016

Some titles may be available electronically through the University library.

  • Kilpatrick, Stephen T. Lewins genes xii

    Jones And Bartlett Publishers,, 2017

    Find in the library