Syllabus for Molecular Imaging with Focus on PET
Molecular imaging med fokus på PET
A revised version of the syllabus is available.
- 7.5 credits
- Course code: 3FK285
- Education cycle: Second cycle
Main field(s) of study and in-depth level:
Pharmaceutical Sciences A1N,
Drug Discovery and Development A1N
Explanation of codes
The code indicates the education cycle and in-depth level of the course in relation to other courses within the same main field of study according to the requirements for general degrees:
- G1N: has only upper-secondary level entry requirements
- G1F: has less than 60 credits in first-cycle course/s as entry requirements
- G1E: contains specially designed degree project for Higher Education Diploma
- G2F: has at least 60 credits in first-cycle course/s as entry requirements
- G2E: has at least 60 credits in first-cycle course/s as entry requirements, contains degree project for Bachelor of Arts/Bachelor of Science
- GXX: in-depth level of the course cannot be classified
- A1N: has only first-cycle course/s as entry requirements
- A1F: has second-cycle course/s as entry requirements
- A1E: contains degree project for Master of Arts/Master of Science (60 credits)
- A2E: contains degree project for Master of Arts/Master of Science (120 credits)
- AXX: in-depth level of the course cannot be classified
- Grading system: Fail (U), Pass (G), Pass with distinction (VG)
- Established: 2016-05-26
- Established by: The Educational Board of Pharmacy
- Revised: 2017-09-21
- Revised by: The Educational Board of Pharmacy
- Applies from: Autumn 2017
For elective course, semester 8, within the pharmacy programme is required 150 credits within the program, of which 60 credits chemistry or 60 credits bioscience. For students within the biomedicine and the physician programmes and for student within the Bachelor's programmes in molecular biology or biotechnology, 135 credits within the programme including 60 credits biology are required. Students who are admitted to the Master's programme in drug development are qualified to read the course. Other education is assessed individually. Knowledge in English equivalent what is required for general entry claims to Swedish first-cycle programmes.
- Responsible department: Department of Medicinal Chemistry
After examination, the student should be able to:
• present the physical processes behind the radionuclide technologies PET and SPECT
• describer the most common methods for radioactive labelling of trace molecules
• plan and evaluate experiments using the most common in the vitro methodologies within MI (bindings experiments on cells or tissue homogenates and autoradiography)
• design and evaluate in vivo studies for visualisation of biological processes using radio-labelled tracers
• understand the bases of quantification of biological processes by means of MI
• discuss how MI can be applied in drug development
• discuss the clinical role of PET and SPECT in modern medicine
Molecular imaging (MI) is essentially a multidisciplinary field. For deeper understanding of the method, it is required that the course illustrates all parts of the process from the physics behind the instruments to radio- labelling of molecules validation of these in vitro and in vivo.. The course will also exemplify the questions which are suitable answered by MI. The course covers radiochemistry in tracer development, preclinical methods for in vitro validation of molecular traces, preclinical in vivo imaging using PET and SPECT tracers, image analysis and image processing tools, quantification and modelling of tracer kinetics, PET, PET as a tool for drug development and the clinical use of PET, e.g. within neurology, oncology, cardiology, metabolic diseases and psychiatry.
The teaching is given as lectures, laboratory sessions and seminars. All parts will be given in English.
Compulsory parts of the course: Course introduction, laboratory sessions and seminars.
Individual written examination is arranged at the end of the course. Laboratory sessions and seminars are compulsory, and attendance on these is required for examination. A chance to finalise a failed compulsory part can be arranged only at the next course occasion and only in case of a vacancy. Each student has the right to six examinations (one examination and five re-examinations).
Tarik F. Massoud and Sanjiv S. Gambhir: Molecular imaging in living subjects: the seeing fundamental biological processes in a new light. Genesis and Development, 2003.
- Latest syllabus (applies from Autumn 2023)
- Previous syllabus (applies from Autumn 2019, version 2)
- Previous syllabus (applies from Autumn 2019, version 1)
- Previous syllabus (applies from Autumn 2018)
- Previous syllabus (applies from Autumn 2017, version 2)
- Previous syllabus (applies from Autumn 2017, version 1)
The reading list is missing. For further information, please contact the responsible department.