Syllabus for Physical Organic Chemistry

Fysikalisk-organisk kemi

A revised version of the syllabus is available.

Syllabus

  • 15 credits
  • Course code: 1KB767
  • Education cycle: Second cycle
  • Main field(s) of study and in-depth level: Chemistry A1N

    Explanation of codes

    The code indicates the education cycle and in-depth level of the course in relation to other courses within the same main field of study according to the requirements for general degrees:

    First cycle

    • G1N: has only upper-secondary level entry requirements
    • G1F: has less than 60 credits in first-cycle course/s as entry requirements
    • G1E: contains specially designed degree project for Higher Education Diploma
    • G2F: has at least 60 credits in first-cycle course/s as entry requirements
    • G2E: has at least 60 credits in first-cycle course/s as entry requirements, contains degree project for Bachelor of Arts/Bachelor of Science
    • GXX: in-depth level of the course cannot be classified

    Second cycle

    • A1N: has only first-cycle course/s as entry requirements
    • A1F: has second-cycle course/s as entry requirements
    • A1E: contains degree project for Master of Arts/Master of Science (60 credits)
    • A2E: contains degree project for Master of Arts/Master of Science (120 credits)
    • AXX: in-depth level of the course cannot be classified

  • Grading system: Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
  • Established: 2017-03-09
  • Established by:
  • Revised: 2018-08-30
  • Revised by: The Faculty Board of Science and Technology
  • Applies from: Spring 2019
  • Entry requirements:

    120 credits with 60 credits in chemistry including 10 credits in organic chemistry and 10 credits in physical chemistry. Proficiency in English equivalent to the Swedish upper secondary course English 6.

  • Responsible department: Department of Chemistry - Ångström Laboratory

Learning outcomes

On completion of the course, the student should be able to:

  • apply qualitative electronic structure theory to predict the geometric structure, reactivity and other properties of organic molecules (including organometallic compounds and conjugated polymers), and apply qualitative theoretical models to describe pericyclic reactions.
  • predict conformational preference of organic molecules and the stereochemical preference in reactions
  • critically evaluate and use different techniques (experimental and computational) for the determination of mechanisms of organic reactions
  • describe different types of reactive intermediates and describe their importance in different reactions
  • apply fundamental concepts of chemical and biochemical catalysis
  • describe various forms of non-covalent interactions in organic, bioorganic and supramolecular systems, and predict the influence of solvent on reactivity
  • describe important processes of organic molecules in electronically excited states

Content

Construction of molecular orbitals for important organic molecules and functional groups. The hybrid orbital concept. Stereoelectronic effects. Hückel theory for conjugated hydrocarbons. Different forms of conjugation and aromaticity. Repetition of thermochemical concepts. Conformational analysis. Introduction to molecular mechanics and quantum chemical calculations. Symmetry operations and stereochemisry. Non-covalent interactions and solvent effects. Molecular recognition and supramolecular chemistry. Reactive intermediates such as carbanions, carbocations, radicals and carbenes. Chemical bonding in organometallic compounds. Potential energy surfaces and transition state theory. Experimental methods for the study of kinetics. Kinetic isotope effects. Linear free energy relationships. Catalysis and biocatalysis. Qualitative models for pericyclic reactions. Alternant and non-alternant hydrocarbons. Band structure of conjugated polymers. Photophysical and photochemical processes of organic compounds.

Instruction

Lectures, tutorial exercise, seminars and laboratory work. Participation in seminars, laboratory work and the associated oral presentations and written reports is mandatory.

Assessment

Written examination in the middle of the course (5 credits) and during the second half of the course (4 credits). Laboratory work corresponds to 3 credits. Oral presentations and assignments correspond to 3 credits. The final grade corresponds to a weighted sum of the results all course components.

If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the disability coordinator of the university.

Other directives

Cannot be counted towards a higher education qualification together with Physical Organic Chemistry NV1 (1KE977), Physical Organic Chemistry NV2 (1KE978) or Physical Organic Chemistry (1KB471).

Syllabus Revisions

Reading list

Reading list

Applies from: Autumn 2019

Some titles may be available electronically through the University library.

  • Anslyn, Eric V.; Dougherty, Dennis A. Modern physical organic chemistry

    Sausalito, CA: University Science Books, 2006

    Find in the library