Selection: Higher education credits in science and engineering (maximum 240 credits)
21 August 2022 – 29 August 2022
Entry requirements: For students from the:
Master's Programmes in Drug Discovery and Development, and Pharmaceutical Modelling the student should have passed the course in Molecular Biopharmaceutics or equivalent.
For acceptance to freestanding course at least 150 credits are required including at least 15 credits in pharmaceutics and pharmacokinetics. Proficiency in English equivalent to the general entry requirements for first-cycle (Bachelor's level) studies.
If you are not a citizen of a European Union (EU) or European Economic Area (EEA) country, or Switzerland, you are required to pay application or tuition fees. Formal exchange students will be exempted from tuition fees, as well as the application fee. Read more about fees.
Application fee: SEK 900
Tuition fee, first semester:
Tuition fee, total:
About the course
The course gives a deep understanding of the molecular properties of drugs and how they affect the choice of drug delivery system and administration route. Furthermore, it describes how pharmacokinetic and pharmacodynamic models are used to predict the bioavailability and effect of drugs for different administration routes.
We relate barrier properties (physiological, biochemical, chemical), transport proteins and enzymes to their importance for drug delivery via different administration routes. This includes cell culture models to study mechanisms of drug transport across biological barriers.
We study intracellular drug delivery and subcellular drug distribution and how to choose appropriate drug delivery systems so that drugs can cross these barriers. The course will furthermore cover formulation principles for different administration routes; pulmonary, parenteral, oral, dermal and vaginal. This includes colloidal and semi-solid systems (e.g. liposomes, gels), solid mesoporous carriers, nanocarriers and prodrug strategies as well as advanced characterisation methods for drug delivery systems in silico and in vitro.
Finally, we will discuss regulatory aspects when choosing a drug delivery system and dosage form.