Genomic and Epigenomic Medicine, 15 credits
Academic year 2023/2024
Spring 2024, 100%, Campus
Start date: 15 January 2024
End date: 17 March 2024
Application deadline: 16 October 2023
Application code: UU-92013 Application
Language of instruction: English
Selection: Higher education credits in science and engineering (maximum 240 credits)
Registration: Please contact the department.
Entry requirements: 180 credits in biology, bio-/medicine, biotechnology, pharmaceutical biosciences, medical science or equivalent education giving relevant knowledge in cell biology, genetics biochemistry and molecular biology. Proficiency in English equivalent to the Swedish upper secondary course English 6.
If you are not a citizen of a European Union (EU) or European Economic Area (EEA) country, or Switzerland, you are required to pay application or tuition fees. Formal exchange students will be exempted from tuition fees, as well as the application fee. Read more about fees.
Application fee: SEK 900
Tuition fee, first semester: SEK 36,250
Tuition fee, total: SEK 36,250
About the course
The course provides an insight into the applications, strategies and implications of the genomic and epigenomic analysis of the human genome, its impact on human diseases and translation into clinical tools. Current opinions and research findings, as well as methods and technologies, will be conveyed and discussed throughout the course. Applications of bioinformatics and computational data analysis will be illustrated.
Genomic structure and variation will be covered as well as population genetics, discussing the HapMap and 1000 genomes projects. The identification of genetic causes and their associations with human diseases will be treated together with genetic epidemiology. The human transcriptome, its regulation, biogenesis and function will be treated. Comparative genomics will illustrate the genetic evolution of man and the use of animal or other model organisms in understanding human diseases.
Epigenomics comprise an in-depth account of the epigenetic mechanisms affecting chromatin structures such as modification of histones and DNA, non-coding RNAs and nuclear structure and their importance in different fundamental biological processes, as shown e.g. in the ENCODE project. Translational genomics will be illustrated by pharmacogenomics/epigenomics, its application in drug therapies for different diseases and its impact on public health and personalised medicine.
Department of Immunology, Genetics and Pathology
Dag Hammarskjölds väg 20
Rudbecklaboratoriet, 751 85 UPPSALA
Telephone: +46 18 471 46 79