Syllabus for Proteins and Drugs

Proteiner och läkemedel

  • 5 credits
  • Course code: 1KB404
  • Education cycle: First cycle
  • Main field(s) of study and in-depth level: Biology G1F, Chemistry G1F
  • Grading system: Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
  • Established: 2008-03-13
  • Established by:
  • Revised: 2018-08-30
  • Revised by: The Faculty Board of Science and Technology
  • Applies from: week 24, 2019
  • Entry requirements: Structure and Function of Proteins, 10 credits
  • Responsible department: Department of Chemistry - BMC

Learning outcomes

On completion of the course, the student should be able to:

  • describe how the properties of proteins relate to various disease processes
  • describe the mechanism of drugs directed against proteins
  • principally design a molecule that interferes with the normal function of a protein
  • experimentally identify and characterise molecules that interfere with the normal functions of proteins
  • produce and present a scientific poster


  • Examples and concepts: Projects defined by protein class, e.g. proteases. Projects by defined disease areas, e.g. cancer, antiviral drugs.
  • Pharmaceutical substances: Nature as a source for drugs. Rational drug design. Fragment based drug discovery.
  • Drug targets: Receptors, ion channels, enzymes, nucleic acids.
  • Biochemical methods for drug development: Target identification and characterisation. Lead identification and characterisation.
  • Lead optimisation: selectivity, resistance, ADME, pro-drugs.
  • From the pharmaceutical industry to the clinic.
  • Individual project: The mechanism of action for a given drug at the biochemical level has to be presented in form of a scientific poster.


The course is given in form of lectures and to a large extent in form of theoretical exercises and projects.
Exercises and projects are compulsory and are carried out individually.


Experimental and theoretical exercises and projects (2.5 credits) are examined during the course. An overall examination (2.5 credits) is given at the end of the course. The final grade for the course is given as a weighted average grade for all compulsory parts. 
If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the disability coordinator of the university.

Reading list

The reading list is missing. For further information, please contact the responsible department.