The purpose of this course is to introduce how electromechanical systems made with micro- and nanotechnology can be used for biological studies, so-called bio-MEMS. The course also includes microfluidic systems.
After passing the course, the student should be able to:
define basic concepts in micro- and nanotechnology,
define basic concepts in microfluidics,
design different bio-MEMS/microfluidic systems for specific biological studies,
discuss the advantages and disadvantages of MEMS-based systems.
Motivate the choice of MEMS-based/microfluidic systems for specific biological studies,
make predictions about the expected results in a bio-MEMS-based systems,
design and manufacture a bio-MEMS/microfluidic based device for a specific application
The history behind MEMS for applications in the life sciences. Basic theory in microfluidics, e.g. laminar flows, hydraulic resistance and capillary effects. Material properties and function, especially concerning polydimethylsiloxane (PDMS). Manufacturing techniques in microfluidics, such as PDMS casting. Setups required to operate a microfluidic system and collect data from it. Chip-based molecular biology. Cell-based chips for biotechnology. Bio-MEMS for cell biology. Tissue microtechnology. Implantable micro-devices.
Lectures, seminars, laboratory work and small projects in groups.
Written exam at the end of the course (3 credits) and participation in the seminar, laboratory work and project report (2 credits).
If there are special reasons, the examiner may make an exception from the specified examination method and allow an individual student to be examined in another way. An example of special reasons might be a certificate regarding special pedagogical support from the University's disability coordinator.
Some titles may be available electronically through the University library.