Syllabus for Pharmaceutical Bioinformatics with Sequence Analysis

Decisions and guidelines

The course is a part of the Master Programme in Pharmaceutical modelling or the Master Programme in Drug Discovery and Development.

Learning outcomes

After having completed the course, the students should be able to:

• describe bioinformatics tools and methods and how they can be used within pharmaceutical research
• use bio- and cheminformatics programs for e.g. sequence analysis, expression analysis, functional predictions, 3D-visualisation, and structure-activity relationship based methods
• locate relevant information in biological and chemical databases
• train, validate and use predictive models based on biochemical data
• describe and carry out basic sequence analysis tasks

Content

The course contains theory and methods for bioinformatics analysis and the basics of how bioinformatics can be used within the pharmacutical area. The course presents introduction and historical account of pharmaceutical bioinformatics, representation of biological and chemical data in computers, biological and chemical databases, theory and methods for analysis of experimental data, sequence analysis, expression analysis, predictive modelling, mode! validation, design of experiments, structure-activity relationships, and applications in pharmaceutical bioinformatics. For computationally demanding analysis high performance computing resources will be used.

Instruction

Teaching is in the form of lecture and computer exercises. Compulsory parts: computer exercises and assignments. The course may be given in English.

Assessment

Passed course demands a passed written individual examination and passed compulsory parts. Completion of compulsory parts of the course may be done earliest at next course instance, if space permits.If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the University's disability coordinator.

Other directives

The course can not be combined with Pharmaceutical bioinformatics 3FF575 or 8FF575, due to overlap in course contents.

This course substitutes and corresponds to 3FF576.