Main field(s) of study and in-depth level:
Molecular Biotechnology A1F,
Applied Biotechnology A1F
Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
The Faculty Board of Science and Technology
Alternative 1) 120 credits including Cell biology, Microbiology, Genomic Experimental Methods, Genome Biology Macromolecular Machines is recommended. Alternative 2: Enrolled in Master Programme in Molecular Biotechnology
Through the course, the students will achieve a deep knowledge in the field of synthetic biology. After the course the student should be able to:
describe how naturally occurring organisms regulate the expression of their genes
describe how biotechnology can alter regulation of the genes
describe how biotechnology can alter the properties of the cell
explain, evaluate and report on practical applications of synthetic biology
plan and carry out a laboratory project aimed at creating replicating systems with new properties that can be regulated
apply a scientific approach to the planning, execution, reporting and interpretation of advanced experiments that are topical in synthetic biology, and to critically analyse the results and generate testable hypotheses from these experiments
critically analyse scientific literature in the area
present and defend summaries based on original papers in the area
develop ethical perspectives in the area
Structure of genetic material as well as expression and regulation of prokaryotic and eukaryotic systems, including their viruses. Advanced biotechnological methods comprising cloning, mutagenesis, PCR technology, synthesis of nucleic acids and DNA sequence determination. Experimental characterisation of structural and functional properties of biomolecules. Bioinformatic analysis and characterisation of genes and biomolecules. Basic theoretical and computational modelling of replicating systems. Laboratory highlighting BioBrick cloning as a methodology in synthetic biology. Ethical aspects.
The course consists of lectures, seminars, labs and literature-based tutorials, all of which are compulsory.
Sections: Laboratory 5 credits; Tutorials and student presentations 1 credit; Theory 4 credits The Laboratory section requires lab performance according to written and oral guidelines. Active discussion and an oral presentation of a topic is required for the tutorials and student presentations section. The theory is examined through written and/or oral exam.