After successful completion of the course, the participant should have the ability to:
account for the theoretical foundation of the most commonly used NMR experiments
relate NMR parameters such as chemical shift, scalar coupling constants, and relaxation time constants to molecular structure
investigate and determine the structure of typical organic chemical compounds (molecular weight up to approx. 500 Da) using suitable nuclear magnetic resonance experiments
perform the most commonly used NMR experiments, and to interpret and document their results
Fundamentals of the NMR phenomenon, relationship between NMR spectra and molecular structure. Recording of routine spectra (1H and 13C), essentials of data processing (e.g., weighting functions). 1D NMR techniques: Decoupling, DEPT, relaxation measurement, magnetisation transfer, NOE difference spectra. 2D NMR techniques: Homo- and heteronuclear correlation (COSY, TOCSY, HSQC, HMBC), measurement of the nuclear Overhauser effect (NOESY, ROESY). Emphasis is on learning the practical use of NMR equipment.
Lectures, seminars, group work and laboratory work. Exercises in written and/or presentation. Laboratory work, and related oral presentation and written reports are mandatory
Written examination is arranged at the end of the course. The laboratory work must also be passed. The written examination corresponds to 2 credits. The laboratory exercises including written and oral presentations are valued as 3 credits.