Jan Hirsch
Professor emeritus at Department of Surgical Sciences; Odontology & Maxillofacial Surgery
- Mobile phone:
- +46 70 394 83 23
- E-mail:
- jan.hirsch@uu.se
- Visiting address:
- Käkkirurgiska kliniken
Akademiska sjukhuset ingång 7879
751 85 UPPSALA - Postal address:
- Käkkirurgiska kliniken
Akademiska sjukhuset ingång 7879
751 85 Uppsala
- CV:
- Download CV
Keywords
- 3d-printing
- reconstructive maxillofacial surgery
- oral cancer hpv and tobacco
- cytology and ai and deep learning
- oral cancer screening

Publications
Recent publications
Part of Computers in Biology and Medicine, p. 1-14, 2025
- DOI for Let it shine: Autofluorescence of Papanicolaou-stain improves AI-based cytological oral cancer detection
- Download full text (pdf) of Let it shine: Autofluorescence of Papanicolaou-stain improves AI-based cytological oral cancer detection
Part of Bioengineering, 2023
- DOI for Analytical Study of Stress Distributions around Screws in Flat Mandibular Bone under In-Plane Loading
- Download full text (pdf) of Analytical Study of Stress Distributions around Screws in Flat Mandibular Bone under In-Plane Loading
A paradigm shift in the prevention and diagnosis of oral squamous cell carcinoma.
Part of Journal of Oral Pathology & Medicine, p. 826-833, 2023
- DOI for A paradigm shift in the prevention and diagnosis of oral squamous cell carcinoma.
- Download full text (pdf) of A paradigm shift in the prevention and diagnosis of oral squamous cell carcinoma.
Dental hygienists and dentists as providers of brush biopsies for oral mucosa screening
Part of International Journal of Dental Hygiene, p. 524-532, 2023
- DOI for Dental hygienists and dentists as providers of brush biopsies for oral mucosa screening
- Download full text (pdf) of Dental hygienists and dentists as providers of brush biopsies for oral mucosa screening
Part of Journal of Maxillofacial and Oral Surgery, p. 23-32, 2022
- DOI for Early Detection of Oral Potentially Malignant Disorders: A Review on Prospective Screening Methods with Regard to Global Challenges
- Download full text (pdf) of Early Detection of Oral Potentially Malignant Disorders: A Review on Prospective Screening Methods with Regard to Global Challenges
All publications
Articles in journal
Part of Computers in Biology and Medicine, p. 1-14, 2025
- DOI for Let it shine: Autofluorescence of Papanicolaou-stain improves AI-based cytological oral cancer detection
- Download full text (pdf) of Let it shine: Autofluorescence of Papanicolaou-stain improves AI-based cytological oral cancer detection
Part of Bioengineering, 2023
- DOI for Analytical Study of Stress Distributions around Screws in Flat Mandibular Bone under In-Plane Loading
- Download full text (pdf) of Analytical Study of Stress Distributions around Screws in Flat Mandibular Bone under In-Plane Loading
A paradigm shift in the prevention and diagnosis of oral squamous cell carcinoma.
Part of Journal of Oral Pathology & Medicine, p. 826-833, 2023
- DOI for A paradigm shift in the prevention and diagnosis of oral squamous cell carcinoma.
- Download full text (pdf) of A paradigm shift in the prevention and diagnosis of oral squamous cell carcinoma.
Dental hygienists and dentists as providers of brush biopsies for oral mucosa screening
Part of International Journal of Dental Hygiene, p. 524-532, 2023
- DOI for Dental hygienists and dentists as providers of brush biopsies for oral mucosa screening
- Download full text (pdf) of Dental hygienists and dentists as providers of brush biopsies for oral mucosa screening
Part of Journal of Maxillofacial and Oral Surgery, p. 23-32, 2022
- DOI for Early Detection of Oral Potentially Malignant Disorders: A Review on Prospective Screening Methods with Regard to Global Challenges
- Download full text (pdf) of Early Detection of Oral Potentially Malignant Disorders: A Review on Prospective Screening Methods with Regard to Global Challenges
Patient-reported pain after surgical removal of leukoplakia: an observational 1-year follow-up study
Part of Acta Odontologica Scandinavica, p. 383-389, 2021
- DOI for Patient-reported pain after surgical removal of leukoplakia: an observational 1-year follow-up study
- Download full text (pdf) of Patient-reported pain after surgical removal of leukoplakia: an observational 1-year follow-up study
Brush Samples of Oral Lesions to FTA Elute Card for High-risk Human Papilloma Virus Diagnosis
Part of Anticancer Research, p. 269-277, 2021
Part of Tandläkartidningen, p. 60-65, 2020
Part of Journal of Clinical Medicine, 2020
- DOI for Fibula Graft Cutting Devices: Are 3D-Printed Cutting Guides More Precise than a Universal, Reusable Osteotomy Jig?
- Download full text (pdf) of Fibula Graft Cutting Devices: Are 3D-Printed Cutting Guides More Precise than a Universal, Reusable Osteotomy Jig?
Part of Applied Sciences, 2020
- DOI for Custom-Made Horizontal and Vertical Maxillary Augmentation with Smartbone® On Demand™: A Seven-Year Follow-Up Case
- Download full text (pdf) of Custom-Made Horizontal and Vertical Maxillary Augmentation with Smartbone® On Demand™: A Seven-Year Follow-Up Case
Part of Journal of plastic, reconstructive & aesthetic surgery : JPRAS, p. 98-102, 2020
Part of PLOS ONE, 2019
- DOI for Recurrence rates after surgical removal of oral leukoplakia: A prospective longitudinal multicentre study
- Download full text (pdf) of Recurrence rates after surgical removal of oral leukoplakia: A prospective longitudinal multicentre study
Part of Anticancer Research, p. 1293-1300, 2019
Screening kan minska insjuknandet i munhålecancer
Part of Tandläkartidningen, p. 50-53, 2017
Part of The Journal of craniofacial surgery (Print), p. 1899-1904, 2016
Part of Plastic and Reconstructive Surgery - Global Open, 2015
Part of Journal of Plastic Surgery and Hand Surgery, p. 95-101, 2015
Failure location predictoin by finite element analysis for an additive manufactured mandible implant
Part of Medical Engineering and Physics, p. 862-869, 2015
Part of In Vivo, p. 65-70, 2015
Virus and tobacco use in premalignant and malignant oral lesions
Part of International Journal of Molecular Medicine, 2015
Part of Journal of Oral Health and Dental Management, 2015
Nested PCR for detection of HSV-1 in oral mucosa
Part of Medicina Oral, 2015
Part of Annals of maxillofacial surgery, p. 178-181, 2014
Surgical approach to snus-induced injury of the oral mucosa
Part of Journal of Oral Science, p. 91-94, 2014
Smokeless tobacco, viruses and oral cancer
Part of Oral health and dental management, p. 372-378, 2014
Part of International Journal of Computer Assisted Radiology and Surgery, p. 887-894, 2013
- DOI for A haptics-assisted cranio-maxillofacial surgery planning system for restoring skeletal anatomy in complex trauma cases
- Download full text (pdf) of A haptics-assisted cranio-maxillofacial surgery planning system for restoring skeletal anatomy in complex trauma cases
Shape and volume of craniofacial cavities in intentional skull deformations
Part of American Journal of Physical Anthropology, p. 110-119, 2013
Telemedicine: a complement to traditional referrals in oral medicine
Part of Telemedicine and e-Health, p. 549-553, 2012
Treatment of sleep apnoea using a mandibular advancement splint: an open prospective study
Part of In Vivo, p. 841-845, 2012
Local Tolerance of a Sublingual Nicotine Tablet: an Open Single-centre Study
Part of In Vivo, p. 463-468, 2012
Oral cancer in Swedish snuff dippers
Part of Anticancer Research, p. 3327-3330, 2012
Virus, genetic alterations and tobacco use in premalignant and malignant oral lesions
Part of International Journal of Molecular Medicine, 2012
Part of Anticancer Research, p. 3345-3351, 2011
Computer-navigated contouring of craniofacial fibrous dysplasia involving the orbit
Part of The Journal of craniofacial surgery (Print), p. 469-472, 2011
Part of Journal of Oral Pathology & Medicine, p. 599-604, 2010
Part of Acta Odontologica Scandinavica, p. 377-384, 2010
Prevalence of viral (HPV, EBV, HSV) infections in oral submucous fibrosis and oral cancer from India
Part of Acta Oto-Laryngologica, p. 1306-1311, 2010
Gene expression analysis by cDNA microarray in oral cancers from two Western populations
Part of Anticancer Research, p. 1083-1091, 2010
Anatomical Variation of Mental Foramen: A case report
Part of Stomatologija, Baltic Dental and Maxillofacial Journal, p. 93-96, 2010
Part of International Journal of Prosthodontics, p. 231-238, 2010
Part of Journal of Cranio-Maxillofacial Surgery, p. 305-11, 2009
Part of International Journal of Computer Assisted Radiology and Surgery, 2009
Virtual bending of mandibular reconstruction plates using a computer-aided design
Part of Journal of oral and maxillofacial surgery (Print), p. 1640-1643, 2009
Part of International Journal of Oral and Maxillofacial Surgery, p. 187-192, 2009
Part of Läkartidningen, p. 2362-2365, 2009
Making new meanings of being in the world after treatment for oral cancer
Part of Qualitative Health Research, p. 1076-1086, 2009
Functional reconstruction of the temporomandibular joint with a free fibular microvascular flap
Part of Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery, p. 233-40, 2008
A comprehensive classification of mandibular fractures: a preliminary agreement validation study
Part of International Journal of Oral and Maxillofacial Surgery, p. 1080-8, 2008
Part of Scandinavian Journal of Caring Sciences, p. 40-47, 2008
Part of Clinical Implant Dentistry and Related Research, p. 23-29, 2008
The role of whole blood in thrombin generation in contact with various titanium surfaces
Part of Biomaterials, p. 966-974, 2007
Part of Journal of oral and maxillofacial surgery (Print), p. 64-72, 2007
The uncanny mouth - a phenomenological approach to oral cancer
Part of Patient Education and Counseling, p. 301-306, 2007
Part of Supportive Care in Cancer, p. 1046-1054, 2006
Part of European Journal of Oral Sciences, p. 527-551, 1998
Part of Journal of materials science. Materials in medicine, p. 535-541, 1998
The Swedish snus and the Sudanese toombak: are they different?
Part of Oral Oncology, p. 558-566, 1998
Biological factors contributing to failures of osseointegrated oralimplants. (II): Etiopathogenesis
Part of European Journal of Oral Sciences, p. 721-764, 1998
Failure patterns of four osseointegrated oral implant systems
Part of Journal of materials science. Materials in medicine, p. 843-847, 1997
Part of International Journal of Cancer, p. 749-753, 1996
Assessment of p53 and Ki-67 expression in snuff-induced lesions
Part of British Journal of Oral & Maxillofacial Surgery, p. 409-413, 1996
Part of British Journal of Oral & Maxillofacial Surgery, p. 276-281, 1995
Reactivated herpes simplex virus infection as a possible cause of dry socket after tooth extraction
Part of Journal of oral and maxillofacial surgery (Print), p. 370-376; discussion 377, 1993
Recrudescence of herpes simplex virus type 1 in latently infected rats after trauma to oral tissues
Part of Journal of Oral Pathology & Medicine, p. 214-220, 1993
Measures of dental beliefs and attitudes: their relationships with measures of fear
Part of Community Dental Health, p. 31-39, 1993
Hemodynamic effects of the use of oral snuff
Part of Clinical Pharmacology and Therapeutics, p. 394-401, 1992
Part of Archives of Oral Biology, p. 969-978, 1992
Non-random chromosome rearrangements in herpes simplex virus type 1 transformed diploid CHEF cells
Part of Anticancer Research, p. 863-868, 1992
Part of Swedish Dental Journal, p. 117-123, 1991
Effect of repeated oral administration of tobacco snuff on natural killer-cell activity in the rat
Part of Archives of Oral Biology, p. 473-476, 1991
Part of Clinical Oral Implants Research, p. 91-96, 1991
Association between development of lower lip cancer and tobacco habits
Part of Journal of oral and maxillofacial surgery (Print), p. 1044-1047; discussion 1048, 1991
Part of Journal of Oral Pathology & Medicine, p. 471-476, 1990
[Single tooth replacement with aid of osseointegration--a modified surgical prosthetic procedure]
Part of Die Quintessenz, p. 1403-1411, 1989
Part of Journal of Oral Pathology & Medicine, p. 187-192, 1989
Snuff-induced carcinogenesis: effect of snuff in rats initiated with 4-nitroquinoline N-oxide
Part of Cancer Research, p. 3063-3069, 1989
Part of Journal of General Virology, p. 1773-1778, 1989
Single-tooth rehabilitation using osseointegration: A modified surgical and prosthodontic approach
Part of Quintessence International, p. 871-876, 1988
Part of International Journal of Oral and Maxillofacial Surgery, p. 330-336, 1988
Part of Clinical preventive dentistry, p. 23-26, 1988
Surgical endodontic retreatment
Part of International Endodontic Journal, p. 107-112, 1986
The reversibility of the snuff-induced lesion: an experimental study in the rat
Part of Journal of Oral Pathology & Medicine, p. 540-543, 1986
Inhibition of herpes simplex virus replication by tobacco extracts
Part of Cancer Research, p. 1991-1997, 1984
Effect of long-term application of snuff on the oral mucosa: an experimental study in the rat
Part of Journal of Oral Pathology & Medicine, p. 187-198, 1983
A clinical, histomorphological and histochemical study on snuff-induced lesions of varying severity
Part of Journal of Oral Pathology & Medicine, p. 387-398, 1982
Snuff-induced lesions of the oral mucosa: an experimental model in the rat
Part of Journal of oral pathology, p. 342-353, 1981
Part of International journal of oral surgery, p. 173-185, 1979
Articles, review/survey
Icke-invasiv kontroll av cellförändringar i munslemhinnan
Part of Tandläkartidningen, p. 48-55, 2021
Viral and Molecular Aspects of Oral Cancer
Part of Anticancer Research, p. 4201-4212, 2012
Chapters in book
Virtual Cranio-Maxillofacial Surgery Planning with Stereo Graphics and Haptics
Part of Computer-Assisted Musculoskeletal Surgery, p. 29-42, Springer, 2016
Conference papers
Part of 3rd NEUBIAS Conference, Luxembourg, 2-8 February 2019, 2019
Part of EAOM2018, 2018
Part of CYTO2018, 2018
Deep convolutional neural networks for detecting cellular changes due to malignancy
Part of Proc. 16th International Conference on Computer Vision Workshops, p. 82-89, 2017
Custom Mandibular Implant Design with Deformable Models and Haptics
Part of Proc. Computer Assisted Radiology and Surgery (CARS). Fukuoka, Japan, June 25-28, p. 246-247, 2014
Finite Element Investigation of the In - Vivo Failure of a Titanium Alloy HumanJaw Implant
2014
Snap-to-fit, a Haptic 6 DOF Alignment Tool for Virtual Assembly
Part of Proc. World Haptics (WHC), 2013 IEEE, p. 205-210, 2013