Jonatan Halvardson

Loss of Y Chromosome and Major Cardiovascular Events in a Prospective Study of Older Men

Hussain, Sultana Monira; Bjurling, Josefin; Yu, Chenglong; Tonkin, Andrew M. et al.

Part of Journal of the American College of Cardiology, p. 36-45, 2026

• DOI for Loss of Y Chromosome and Major Cardiovascular Events in a Prospective Study of Older Men

Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease

Arai, Yohei; Chavkin, Nicholas W.; Arai, Yuka; Halvardson, Jonatan et al.

Part of Science Translational Medicine, 2025

• DOI for Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease

Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis

Bjurling, Josefin; Chavkin, Nicholas W.; Halvardson, Jonatan; Thel, Mark C. et al.

Part of Communications Medicine, 2025

• DOI for Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis
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Loss of chromosome Y in regulatory T cells

Mattisson, Jonas; Halvardson, Jonatan; Davies, Hanna; Bruhn-Olszewska, Bozena et al.

Part of BMC Genomics, 2024

• DOI for Loss of chromosome Y in regulatory T cells
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Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?

Ljungström, Viktor; Mattisson, Jonas; Halvardson, Jonatan; Pandzic, Tatjana et al.

Part of Leukemia, p. 889-891, 2022

• DOI for Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?
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Loss of Y Chromosome and Major Cardiovascular Events in a Prospective Study of Older Men

Hussain, Sultana Monira; Bjurling, Josefin; Yu, Chenglong; Tonkin, Andrew M. et al.

Part of Journal of the American College of Cardiology, p. 36-45, 2026

• DOI for Loss of Y Chromosome and Major Cardiovascular Events in a Prospective Study of Older Men

Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease

Arai, Yohei; Chavkin, Nicholas W.; Arai, Yuka; Halvardson, Jonatan et al.

Part of Science Translational Medicine, 2025

• DOI for Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease

Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis

Bjurling, Josefin; Chavkin, Nicholas W.; Halvardson, Jonatan; Thel, Mark C. et al.

Part of Communications Medicine, 2025

• DOI for Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis
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Loss of chromosome Y in regulatory T cells

Mattisson, Jonas; Halvardson, Jonatan; Davies, Hanna; Bruhn-Olszewska, Bozena et al.

Part of BMC Genomics, 2024

• DOI for Loss of chromosome Y in regulatory T cells
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Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?

Ljungström, Viktor; Mattisson, Jonas; Halvardson, Jonatan; Pandzic, Tatjana et al.

Part of Leukemia, p. 889-891, 2022

• DOI for Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?
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Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality

Sano, Soichi; Horitani, Keita; Ogawa, Hayato; Halvardson, Jonatan et al.

Part of Science, p. 292-297, 2022

• DOI for Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality

Immune cells lacking Y chromosome show dysregulation of autosomal gene expression

Dumanski, Jan P.; Halvardson, Jonatan; Davies, Hanna; Rychlicka-Buniowska, Edyta et al.

Part of Cellular and Molecular Life Sciences (CMLS), p. 4019-4033, 2021

• DOI for Immune cells lacking Y chromosome show dysregulation of autosomal gene expression
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Reply to Veitia

Danielsson, Marcus; Halvardson, Jonatan; Mattisson, Jonas; Forsberg, Lars A.

Part of European Journal of Human Genetics, p. 1323-1324, 2021

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Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99

Mattisson, Jonas; Danielsson, Marcus; Hammond, Maria; Davies, Hanna et al.

Part of Scientific Reports, 2021

• DOI for Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99
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A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells

Riaz, Moeen; Mattisson, Jonas; Polekhina, Galina; Bakshi, Andrew et al.

Part of Cell & Bioscience, 2021

• DOI for A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells
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Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients

Lindholm Carlström, Eva; Niazi, Adnan; Etemadikhah, Mitra; Halvardson, Jonatan et al.

Part of Genes, 2021

• DOI for Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients
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Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder

Ramos, Jillian; Proven, Melissa; Halvardson, Jonatan; Hagelskamp, Felix et al.

Part of RNA, p. 1654-1666, 2020

• DOI for Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder
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Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals

Danielsson, Marcus; Halvardson, Jonatan; Davies, Hanna; Moghadam, Behrooz Torabi et al.

Part of European Journal of Human Genetics, p. 349-357, 2020

• DOI for Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals
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Linkage and exome analysis implicate multiple genes in non-syndromic intellectual disability in a large Swedish family

Lindholm Carlström, Eva; Halvardson, Jonatan; Etemadikhah, Mitra; Wetterberg, Lennart et al.

Part of BMC Medical Genomics, 2019

• DOI for Linkage and exome analysis implicate multiple genes in non-syndromic intellectual disability in a large Swedish family
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Genetic predisposition to mosaic Y chromosome loss in blood

Thompson, Deborah J; Genovese, Giulio; Halvardson, Jonatan; Ulirsch, Jacob C et al.

Part of Nature, p. 652-657, 2019

• DOI for Genetic predisposition to mosaic Y chromosome loss in blood

Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development

Johansson, Martin M.; Pottmeier, Philipp; Suciu, Pascalina; Ahmed, Tauseef et al.

Part of Frontiers in Genetics, 2019

• DOI for Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development
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Mosaic loss of chromosome Y in leukocytes matters

Forsberg, Lars A.; Halvardson, Jonatan; Rychlicka-Buniowska, Edyta; Danielsson, Marcus et al.

Part of Nature Genetics, p. 4-7, 2019

• DOI for Mosaic loss of chromosome Y in leukocytes matters

Whole genome sequencing of consanguineous families reveals novel pathogenic variants in intellectual disability

Thuresson, Ann-Charlotte; Zander, Cecilia; Zhao, Jin James; Halvardson, Jonatan et al.

Part of Clinical Genetics, p. 436-439, 2019

• DOI for Whole genome sequencing of consanguineous families reveals novel pathogenic variants in intellectual disability
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Exome sequencing reveals NAA15 and PUF60 as candidate genes associated with intellectual disability

Zhao, Jin James; Halvardson, Jonatan; Zander, Cecilia; Zaghlool, Ammar et al.

Part of American Journal of Medical Genetics Part B, p. 10-20, 2018

• DOI for Exome sequencing reveals NAA15 and PUF60 as candidate genes associated with intellectual disability
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Reduced cell surface levels of GPI-linked markers in a new case with PIGG loss of function

Zhao, Jin James; Halvardson, Jonatan; Knaus, Alexej; Georgii-Hemming, Patrik et al.

Part of Human Mutation, p. 1394-1401, 2017

• DOI for Reduced cell surface levels of GPI-linked markers in a new case with PIGG loss of function
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Mutations in HECW2 are associated with intellectual disability and epilepsy

Halvardson, Jonatan; Zhao, Jin J.; Zaghlool, Ammar; Wentzel, Christian et al.

Part of Journal of Medical Genetics, p. 697-704, 2016

• DOI for Mutations in HECW2 are associated with intellectual disability and epilepsy
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Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development

Johansson, Martin; Lundin, Elin; Qian, Xiaoyan; Mirzazadeh, Mohammadreza et al.

Part of Biology of Sex Differences, 2016

• DOI for Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development
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A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment

Zaghlool, Ammar; Halvardson, Jonatan; Zhao, Jin J.; Etemadikhah, Mitra et al.

Part of Human Mutation, p. 964-975, 2016

• DOI for A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment
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Transcriptome Profiling Reveals Degree of Variability in Induced Pluripotent Stem Cell Lines: Impact for Human Disease Modeling

Schuster, Jens; Halvardson, Jonatan; Lorenzo, Laureanne Pilar; Ameur, Adam et al.

Part of Cellular Reprogramming, p. 327-337, 2015

• DOI for Transcriptome Profiling Reveals Degree of Variability in Induced Pluripotent Stem Cell Lines: Impact for Human Disease Modeling

Deleterious mutation in FDX1L gene is associated with a novel mitochondrial muscle myopathy

Spiegel, Ronen; Saada, Ann; Halvardson, Jonatan; Soiferman, Devorah et al.

Part of European Journal of Human Genetics, p. 902-906, 2014

• DOI for Deleterious mutation in FDX1L gene is associated with a novel mitochondrial muscle myopathy

Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues

Zaghlool, Ammar; Ameur, Adam; Nyberg, Linnea; Halvardson, Jonatan et al.

Part of BMC Biotechnology, p. 99, 2013

• DOI for Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues
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Exome RNA sequencing reveals rare and novel alternative transcripts

Halvardson, Jonatan; Zaghlool, Ammar; Feuk, Lars

Part of Nucleic Acids Research, 2013

• DOI for Exome RNA sequencing reveals rare and novel alternative transcripts

RNA-binding protein QKI regulates Glial fibrillary acidic protein expression in human astrocytes

Radomska, Katarzyna J.; Halvardson, Jonatan; Reinius, Björn; Carlström, Eva Lindholm et al.

Part of Human Molecular Genetics, p. 1373-1382, 2013

• DOI for RNA-binding protein QKI regulates Glial fibrillary acidic protein expression in human astrocytes

Intractable epilepsy of infancy due to homozygous mutation in the EFHC1 gene

Berger, Itai; Dor, Talya; Halvardson, Jonatan; Edvardson, Simon et al.

Part of Epilepsia, p. 1436-1440, 2012

• DOI for Intractable epilepsy of infancy due to homozygous mutation in the EFHC1 gene

Infantile Cerebellar-Retinal Degeneration Associated with a Mutation in Mitochondrial Aconitase, ACO2

Spiegel, Konen; Pines, Ophry; Ta-Shma, Asaf; Burak, Efrat et al.

Part of American Journal of Human Genetics, p. 518-523, 2012

• DOI for Infantile Cerebellar-Retinal Degeneration Associated with a Mutation in Mitochondrial Aconitase, ACO2

Total RNA sequencing reveals nascent transcription and widespread co-transcriptional splicing in the human brain

Ameur, Adam; Zaghlool, Ammar; Halvardson, Jonatan; Wetterbom, Anna et al.

Part of Nature Structural & Molecular Biology, p. 1435-1440, 2011

• DOI for Total RNA sequencing reveals nascent transcription and widespread co-transcriptional splicing in the human brain

Sequence based analysis of neurodevelopmental disorders

Halvardson, Jonatan

2016

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Mutation in the chromatin-remodeling factor BAZ1A is associated with intellectual disability

Zaghlool, Ammar; Halvardson, Jonatan; Zhao, Jin; Kalushkova, Antonia et al.