Mikael Nissbeck

PARN – The Tail End: Function and mechanisms of specificity and processivity

Nissbeck, Mikael

2019

• Download full text (pdf) of PARN – The Tail End: Function and mechanisms of specificity and processivity

From incomplete penetrance with normal telomere length to severe disease and telomere shortening in a family with monoallelic and biallelic PARN pathogenic variants

Dodson, Lois M.; Baldan, Alessandro; Nissbeck, Mikael; Gunja, Sethu Madhava Rao et al.

Part of Human Mutation, p. 2414-2429, 2019

• DOI for From incomplete penetrance with normal telomere length to severe disease and telomere shortening in a family with monoallelic and biallelic PARN pathogenic variants

Insights from engineering the Affibody-Fc interaction with a computational-experimental method

Nosrati, Masoumeh; Solbak, Sara; Nordesjö, Olle; Nissbeck, Mikael et al.

Part of Protein Engineering Design & Selection, p. 593-601, 2017

• DOI for Insights from engineering the Affibody-Fc interaction with a computational-experimental method

Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN)

Dhanraj, Santhosh; Gunja, Sethu Madhava Rao; Deveau, Adam P.; Nissbeck, Mikael et al.

Part of Journal of Medical Genetics, p. 738-748, 2015

• DOI for Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN)

Bone Marrow Failure and Developmental Delay Caused By Mutations in Poly(A)-Specific Ribonuclease

Dhanraj, Santhosh; Gunja, Sethu Madhava Rao; Deveau, Adam P.; Nissbeck, Mikael et al.

Part of Blood, 2015

From incomplete penetrance with normal telomere length to severe disease and telomere shortening in a family with monoallelic and biallelic PARN pathogenic variants

Dodson, Lois M.; Baldan, Alessandro; Nissbeck, Mikael; Gunja, Sethu Madhava Rao et al.

Part of Human Mutation, p. 2414-2429, 2019

• DOI for From incomplete penetrance with normal telomere length to severe disease and telomere shortening in a family with monoallelic and biallelic PARN pathogenic variants

Insights from engineering the Affibody-Fc interaction with a computational-experimental method

Nosrati, Masoumeh; Solbak, Sara; Nordesjö, Olle; Nissbeck, Mikael et al.

Part of Protein Engineering Design & Selection, p. 593-601, 2017

• DOI for Insights from engineering the Affibody-Fc interaction with a computational-experimental method

Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN)

Dhanraj, Santhosh; Gunja, Sethu Madhava Rao; Deveau, Adam P.; Nissbeck, Mikael et al.

Part of Journal of Medical Genetics, p. 738-748, 2015

• DOI for Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN)

Bone Marrow Failure and Developmental Delay Caused By Mutations in Poly(A)-Specific Ribonuclease

Dhanraj, Santhosh; Gunja, Sethu Madhava Rao; Deveau, Adam P.; Nissbeck, Mikael et al.

Part of Blood, 2015

Specificity for adenine is established during the hydrolytic cycle of poly(A)-specific ribonuclease (PARN): Mechanism for poly(A) selectivity by PARN

Nissbeck, Nissbeck; Henriksson, Niklas; Nilsson, Per; Berndtsson, Jens et al.

Poly(A)-specific ribonuclease (PARN): An allosterically regulated, processive and mRNA cap-interacting deadenylase

Virtanen, Anders; Henriksson, Niklas; Nilsson, Per; Nissbeck, Mikael

Part of Critical reviews in biochemistry and molecular biology, p. 192-209, 2013

• DOI for Poly(A)-specific ribonuclease (PARN): An allosterically regulated, processive and mRNA cap-interacting deadenylase

PARN – The Tail End: Function and mechanisms of specificity and processivity

Nissbeck, Mikael

2019

• Download full text (pdf) of PARN – The Tail End: Function and mechanisms of specificity and processivity

Mechanisms of PARN action: Kinetic analysis of processive mode of degradation

Nissbeck, Mikael; Emmerich, Andrew; Ehrenberg, Måns; Virtanen, Anders

Mechanisms of PARN action: Specificity and requirement for the 2’OH groups of the substrate

Nissbeck, Mikael; Virtanen, Anders