Ida Alenkvist

Recruitment of Epac2A to Insulin Granule Docking Sites Regulates Priming for Exocytosis

Alenkvist, Ida; Gandasi, Nikhil R; Barg, Sebastian; Tengholm, Anders

Part of Diabetes, p. 2610-2622, 2017

• DOI for Recruitment of Epac2A to Insulin Granule Docking Sites Regulates Priming for Exocytosis

Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes

Tuomi, Tiinamaija; Nagorny, Cecilia L. F.; Singh, Pratibha; Bennet, Hedvig et al.

Part of Cell Metabolism, p. 1067-1077, 2016

• DOI for Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes

Epac2 signaling at the β-cell plasma membrane

Alenkvist, Ida

2016

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Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

Alenkvist, Ida; Dyachok, Oleg; Tian, Geng; Li, Jia et al.

Part of Journal of Endocrinology, p. 267-275, 2014

• DOI for Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets
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Spatial Control of Epac2 Activity by cAMP and Ca2+-Mediated Activation of Ras in Pancreatic beta Cells

Idevall-Hagren, Olof; Jakobsson, Ida; Xu, Yunjian; Tengholm, Anders

Part of Science Signaling, 2013

• DOI for Spatial Control of Epac2 Activity by cAMP and Ca2+-Mediated Activation of Ras in Pancreatic beta Cells

Recruitment of Epac2A to Insulin Granule Docking Sites Regulates Priming for Exocytosis

Alenkvist, Ida; Gandasi, Nikhil R; Barg, Sebastian; Tengholm, Anders

Part of Diabetes, p. 2610-2622, 2017

• DOI for Recruitment of Epac2A to Insulin Granule Docking Sites Regulates Priming for Exocytosis

Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes

Tuomi, Tiinamaija; Nagorny, Cecilia L. F.; Singh, Pratibha; Bennet, Hedvig et al.

Part of Cell Metabolism, p. 1067-1077, 2016

• DOI for Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes

Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

Alenkvist, Ida; Dyachok, Oleg; Tian, Geng; Li, Jia et al.

Part of Journal of Endocrinology, p. 267-275, 2014

• DOI for Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets
• Download full text (pdf) of Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

Spatial Control of Epac2 Activity by cAMP and Ca2+-Mediated Activation of Ras in Pancreatic beta Cells

Idevall-Hagren, Olof; Jakobsson, Ida; Xu, Yunjian; Tengholm, Anders

Part of Science Signaling, 2013

• DOI for Spatial Control of Epac2 Activity by cAMP and Ca2+-Mediated Activation of Ras in Pancreatic beta Cells

DNA Methylation of Alternative Promoters Directs Tissue Specific Expression of Epac2 Isoforms

Hoivik, Erling A.; Witsoe, Solveig L.; Bergheim, Inger R.; Xu, Yunjian et al.

Part of PLOS ONE, 2013

• DOI for DNA Methylation of Alternative Promoters Directs Tissue Specific Expression of Epac2 Isoforms
• Download full text (pdf) of DNA Methylation of Alternative Promoters Directs Tissue Specific Expression of Epac2 Isoforms

Epac2 signaling at the β-cell plasma membrane

Alenkvist, Ida

2016

• Download full text (pdf) of Epac2 signaling at the β-cell plasma membrane

Two-step membrane recruitment of Epac2 primes secretory granules for exocytosis

Alenkvist, Ida; Gandasi, Nikhil R; Barg, Sebastian; Tengholm, Anders

Localization of Epac2 to the plasma membrane is controlled by an interplay between cAMP, Ca²⁺ and PtdIns(4,5)P₂

Alenkvist, Ida; Idevall-Hagren, Olof; Tengholm, Anders

Sulfonylureas trigger Ca²⁺-dependent Epac2 recruitment and Rap activation at the plasma membrane in β-cells

Alenkvist, Ida; Xu, Yunjian; Tengholm, Anders