Sven Nelander

Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts

Almstedt, Elin; Rosén, Emil; Gloger, Marleen; Rebecka, Stockard et al.

Part of Neuro-Oncology, p. 726-738, 2021

• DOI for Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
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Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Lundin, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Part of Molecular Systems Biology, 2021

• DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
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Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma

Vinel, Claire; Rosser, Gabriel; Guglielmi, Loredana; Constantinou, Myrianni et al.

Part of Nature Communications, 2021

• DOI for Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
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Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

Kerzeli, Iliana Kyriaki; Lord, Martin; Doroszko, Milena; Elgendy, Ramy et al.

Part of PLOS ONE, 2021

• DOI for Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
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A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

Johansson, Patrik; Krona, Cecilia; Kundu, Soumi; Doroszko, Milena et al.

Part of Cell Reports, 2020

• DOI for A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
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Integrative discovery of treatments for high-risk neuroblastoma

Almstedt, Elin; Elgendy, Ramy; Hekmati, Neda; Rosén, Emil et al.

Part of Nature Communications, 2020

• DOI for Integrative discovery of treatments for high-risk neuroblastoma
• Download full text (pdf) of Integrative discovery of treatments for high-risk neuroblastoma

HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment

Johard, Helena; Omelyanenko, Anna; Fei, Gao; Zilberter, Misha et al.

Part of Molecular Cancer Research, p. 1522-1533, 2020

• DOI for HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment

BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Cancer, Matko; Drews, Lisa F.; Bengtsson, Johan; Bolin, Sara et al.

Part of Cell Death and Disease, 2019

• DOI for BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
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LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Xie, Yuan; Sundström, Anders; Maturi, Naga P; Tan, E-Jean et al.

Part of Journal of Pathology, p. 228-240, 2019

• DOI for LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

Baskaran, Sathishkumar; Mayrhofer, Markus; Göransson Kultima, Hanna; Bergström, Tobias et al.

Part of Neuro-Oncology, p. 1080-1091, 2018

• DOI for Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
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Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin

Jiang, Yiwen; Marinescu, Voichita Dana; Xie, Yuan; Jarvius, Malin et al.

Part of Cell Reports, p. 977-990, 2017

• DOI for Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
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Anatomically aware simulation of patient-specific glioblastoma xenografts

Malik, Adam A.; Krona, Cecilia; Kundu, Soumi; Gerlee, Philip et al.

Part of PloS Computational Biology, 2026

• DOI for Anatomically aware simulation of patient-specific glioblastoma xenografts
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The invasion phenotypes of glioblastoma depend on plastic and reprogrammable cell states

Doroszko, Milena; Stockgard, Rebecka; Uppman, Irem; Heinold, Josephine et al.

Part of Nature Communications, 2025

• DOI for The invasion phenotypes of glioblastoma depend on plastic and reprogrammable cell states
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Mathematical modeling of multicellular tumor spheroids quantifies inter-patient and intra-tumor heterogeneity

Malik, Adam A.; Nguyen, Kyle C.; Nardini, John T.; Krona, Cecilia et al.

Part of npj Systems Biology and Applications, 2025

• DOI for Mathematical modeling of multicellular tumor spheroids quantifies inter-patient and intra-tumor heterogeneity
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Brain tumors induce immunoregulatory dendritic cells in draining lymph nodes that can be targeted by OX40 agonist treatment

Badillo-Godinez, Oscar; Niemi, Jenni; Helfridsson, Liam; Karimi, Shokoufeh et al.

Part of Journal for ImmunoTherapy of Cancer, 2025

• DOI for Brain tumors induce immunoregulatory dendritic cells in draining lymph nodes that can be targeted by OX40 agonist treatment
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Lineage specification in glioblastoma is regulated by METTL7B

Constantinou, Myrianni; Nicholson, James; Zhang, Xinyu; Maniati, Eleni et al.

Part of Cell Reports, 2024

• DOI for Lineage specification in glioblastoma is regulated by METTL7B
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Anatomically aware simulation of patient-specific glioblastoma xenografts

Malik, Adam A.; Krona, Cecilia; Kundu, Soumi; Gerlee, Philip et al.

Part of PloS Computational Biology, 2026

• DOI for Anatomically aware simulation of patient-specific glioblastoma xenografts
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The invasion phenotypes of glioblastoma depend on plastic and reprogrammable cell states

Doroszko, Milena; Stockgard, Rebecka; Uppman, Irem; Heinold, Josephine et al.

Part of Nature Communications, 2025

• DOI for The invasion phenotypes of glioblastoma depend on plastic and reprogrammable cell states
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Mathematical modeling of multicellular tumor spheroids quantifies inter-patient and intra-tumor heterogeneity

Malik, Adam A.; Nguyen, Kyle C.; Nardini, John T.; Krona, Cecilia et al.

Part of npj Systems Biology and Applications, 2025

• DOI for Mathematical modeling of multicellular tumor spheroids quantifies inter-patient and intra-tumor heterogeneity
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Brain tumors induce immunoregulatory dendritic cells in draining lymph nodes that can be targeted by OX40 agonist treatment

Badillo-Godinez, Oscar; Niemi, Jenni; Helfridsson, Liam; Karimi, Shokoufeh et al.

Part of Journal for ImmunoTherapy of Cancer, 2025

• DOI for Brain tumors induce immunoregulatory dendritic cells in draining lymph nodes that can be targeted by OX40 agonist treatment
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Lineage specification in glioblastoma is regulated by METTL7B

Constantinou, Myrianni; Nicholson, James; Zhang, Xinyu; Maniati, Eleni et al.

Part of Cell Reports, 2024

• DOI for Lineage specification in glioblastoma is regulated by METTL7B
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Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers

Larsson, Ida; Held, Felix; Popova, Gergana; Koc, Alper et al.

Part of Nature Communications, 2024

• DOI for Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers
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Inference of glioblastoma migration and proliferation rates using single time-point images

Rosén, Emil; Mangukiya, Hitesh; Elfineh, Lioudmila; Stockgard, Rebecka et al.

Part of Communications Biology, 2023

• DOI for Inference of glioblastoma migration and proliferation rates using single time-point images
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Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

Ilkhanizadeh, Shirin; Gracias, Aileen; Aslund, Andreas K. O.; Back, Marcus et al.

Part of ACS Applied Bio Materials, p. 3790-3797, 2023

• DOI for Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
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Fast and accurate gene regulatory network inference by normalized least squares regression

Hillerton, Thomas; Secilmi, Deniz; Nelander, Sven; Sonnhammer, Erik L. L. et al.

Part of Bioinformatics, p. 2263-2268, 2022

• DOI for Fast and accurate gene regulatory network inference by normalized least squares regression
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Knowledge of the perturbation design is essential for accurate gene regulatory network inference

Secilmis, Deniz; Hillerton, Thomas; Tjärnberg, Andreas; Nelander, Sven et al.

Part of Scientific Reports, 2022

• DOI for Knowledge of the perturbation design is essential for accurate gene regulatory network inference
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Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape

Boot, James; Rosser, Gabriel; Kancheva, Dailya; Vinel, Claire et al.

Part of eLIFE, 2022

• DOI for Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape
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Optimal Sparsity Selection Based on an Information Criterion for Accurate Gene Regulatory Network Inference

Secilmis, Deniz; Nelander, Sven; Sonnhammer, Erik L. L.

Part of Frontiers in Genetics, 2022

• DOI for Optimal Sparsity Selection Based on an Information Criterion for Accurate Gene Regulatory Network Inference
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MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner

Castell, Alina; Yan, Qinzi; Fawkner, Karin; Bazzar, Wesam et al.

Part of Cancer Research Communications, p. 182-201, 2022

• DOI for MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner
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Autocrine signaling can explain the emergence of Allee effects in cancer cell populations

Gerlee, Philip; Altrock, Philipp M.; Malik, Adam; Krona, Cecilia et al.

Part of PloS Computational Biology, 2022

• DOI for Autocrine signaling can explain the emergence of Allee effects in cancer cell populations
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Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Dalmo, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Part of Molecular Systems Biology, 2021

• DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
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Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts

Almstedt, Elin; Rosén, Emil; Gloger, Marleen; Rebecka, Stockard et al.

Part of Neuro-Oncology, p. 726-738, 2021

• DOI for Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
• Download full text (pdf) of Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts

Inferring the experimental design for accurate gene regulatory network inference

Secilmis, Deniz; Hillerton, Thomas; Nelander, Sven; Sonnhammer, Erik L. L.

Part of Bioinformatics, p. 3553-3559, 2021

• DOI for Inferring the experimental design for accurate gene regulatory network inference
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p53-Mediated Radiosensitization of ¹⁷⁷Lu-DOTATATE in Neuroblastoma Tumor Spheroids

Lundsten, Sara; Berglund, Hanna; Jha, Preeti; Krona, Cecilia et al.

Part of Biomolecules, 2021

• DOI for p53-Mediated Radiosensitization of ¹⁷⁷Lu-DOTATATE in Neuroblastoma Tumor Spheroids
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Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Lundin, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Part of Molecular Systems Biology, 2021

• DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
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Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma

Vinel, Claire; Rosser, Gabriel; Guglielmi, Loredana; Constantinou, Myrianni et al.

Part of Nature Communications, 2021

• DOI for Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
• Download full text (pdf) of Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma

NF1 regulates mesenchymal gliblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

Marques, Carolina; Unterkircher, Thomas; Kroon, Paula; Oldrini, Barbara et al.

Part of eLIFE, 2021

• DOI for NF1 regulates mesenchymal gliblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
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Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

Kerzeli, Iliana Kyriaki; Lord, Martin; Doroszko, Milena; Elgendy, Ramy et al.

Part of PLOS ONE, 2021

• DOI for Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
• Download full text (pdf) of Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

Johansson, Patrik; Krona, Cecilia; Kundu, Soumi; Doroszko, Milena et al.

Part of Cell Reports, 2020

• DOI for A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
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Uncovering cancer gene regulation by accurate regulatory network inference from uninformative data

Secilmis, Deniz; Hillerton, Thomas; Morgan, Daniel; Tjärnberg, Andreas et al.

Part of npj Systems Biology and Applications, 2020

• DOI for Uncovering cancer gene regulation by accurate regulatory network inference from uninformative data
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Integrative discovery of treatments for high-risk neuroblastoma

Almstedt, Elin; Elgendy, Ramy; Hekmati, Neda; Rosén, Emil et al.

Part of Nature Communications, 2020

• DOI for Integrative discovery of treatments for high-risk neuroblastoma
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Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

Dalmo, Erika; Johansson, Patrik; Niklasson, Mia; Gustavsson, Ida et al.

Part of Molecular Cancer Research, p. 981-991, 2020

• DOI for Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma

Merisaari, Joni; Denisova, Oxana; Doroszko, Milena; Le Joncour, Vadim et al.

Part of Brain Communications, 2020

• DOI for Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma
• Download full text (pdf) of Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma

Astrocytes enhance glioblastoma growth.

Mega, Alessandro; Hartmark Nilsen, Mette; Leiss, Lina Wik; Tobin, Nicholas P et al.

Part of Glia, p. 316-327, 2020

• DOI for Astrocytes enhance glioblastoma growth.

HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment

Johard, Helena; Omelyanenko, Anna; Fei, Gao; Zilberter, Misha et al.

Part of Molecular Cancer Research, p. 1522-1533, 2020

• DOI for HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment

BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Cancer, Matko; Drews, Lisa F.; Bengtsson, Johan; Bolin, Sara et al.

Part of Cell Death and Disease, 2019

• DOI for BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
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Increasing the accuracy of glioblastoma subtypes: Factoring in the tumor's cell of origin

Nelander, Sven

Part of Molecular & Cellular Oncology, 2019

• DOI for Increasing the accuracy of glioblastoma subtypes: Factoring in the tumor's cell of origin
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Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors

Kaffes, Ioannis; Szulzewsky, Frank; Chen, Zhihong; Herting, Cameron J. et al.

Part of Oncoimmunology, 2019

• DOI for Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
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Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes

Weishaupt, Holger; Johansson, Patrik; Sundström, Anders; Lubovac-Pilav, Zelmina et al.

Part of Bioinformatics, p. 3357-3364, 2019

• DOI for Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes
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Integrin alpha 10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival

Thoren, Matilda Munksgaard; Masoumi, Katarzyna Chmielarska; Krona, Cecilia; Huang, Xiaoli et al.

Part of Cancers, 2019

• DOI for Integrin alpha 10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival
• Download full text (pdf) of Integrin alpha 10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival

LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Xie, Yuan; Sundström, Anders; Maturi, Naga P; Tan, E-Jean et al.

Part of Journal of Pathology, p. 228-240, 2019

• DOI for LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Image-Based Detection of Patient-Specific Drug-Induced Cell-Cycle Effects in Glioblastoma

Matuszewski, Damian J.; Wählby, Carolina; Krona, Cecilia; Nelander, Sven et al.

Part of SLAS Discovery, p. 1030-1039, 2018

• DOI for Image-Based Detection of Patient-Specific Drug-Induced Cell-Cycle Effects in Glioblastoma

Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

Baskaran, Sathishkumar; Mayrhofer, Markus; Göransson Kultima, Hanna; Bergström, Tobias et al.

Part of Neuro-Oncology, p. 1080-1091, 2018

• DOI for Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
• Download full text (pdf) of Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin

Jiang, Yiwen; Marinescu, Voichita Dana; Xie, Yuan; Jarvius, Malin et al.

Part of Cell Reports, p. 977-990, 2017

• DOI for Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
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c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

Heiland, Dieter H.; Ferrarese, Roberto; Claus, Rainer; Dai, Fangping et al.

Part of Oncotarget, p. 6940-6954, 2017

• DOI for c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses

Niklasson, Mia; Maddalo, Gianluca; Sramkova, Zuzana; Mutlu, Ercan et al.

Part of Cancer Research, p. 1741-1752, 2017

• DOI for Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses

Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression

Fedele, Vita; Dai, Fangping; Masilamani, Anie P.; Heiland, Dieter H. et al.

Part of Molecular Cancer Research, p. 998-1011, 2017

• DOI for Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression

FC1000: normalized gene expression changes of systematically perturbed human cells

Lönnstedt, Ingrid M.; Nelander, Sven

Part of Statistical Applications in Genetics and Molecular Biology, p. 217-242, 2017

• DOI for FC1000: normalized gene expression changes of systematically perturbed human cells
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Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Ramachandran, Mohanraj; Yu, Di; Dyczynski, Matheus; Baskaran, Sathishkumar et al.

Part of Clinical Cancer Research, p. 1519-1530, 2017

• DOI for Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks

Weishaupt, Holger; Johansson, Patrik; Engström, Christopher; Nelander, Sven et al.

Part of Methodology and Computing in Applied Probability, p. 1089-1105, 2017

• DOI for Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks
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Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Darmanis, Spyros; Gallant, Caroline Julie; Marinescu, Voichita Dana; Niklasson, Mia et al.

Part of Cell Reports, p. 380-389, 2016

• DOI for Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
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Case-specific potentiation of glioblastoma drugs by pterostilbene

Schmidt, Linnéa; Baskaran, Sathishkumar; Johansson, Patrik; Padhan, Narendra et al.

Part of Oncotarget, p. 73200-73215, 2016

• DOI for Case-specific potentiation of glioblastoma drugs by pterostilbene

High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

Padhan, Narendra; Nordling, Torbjorn E. M.; Sundström, Magnus; Åkerud, Peter et al.

Part of BMC Cancer, 2016

• DOI for High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer
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Genome-wide association study identifies multiple susceptibility loci for multiple myeloma

Mitchell, Jonathan S.; Li, Ni; Weinhold, Niels; Försti, Asta et al.

Part of Nature Communications, 2016

• DOI for Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
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ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells

Wee, Boyoung; Pietras, Alexander; Ozawa, Tatsuya; Bazzoli, Elena et al.

Part of Scientific Reports, 2016

• DOI for ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells
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Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma

Kling, Teresia; Ferrarese, Roberto; Ailin, Darren Oh; Johansson, Patrik et al.

Part of EBioMedicine, p. 72-85, 2016

• DOI for Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma
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Travelling wave analysis of a mathematical model of glioblastoma growth

Gerlee, Philip; Nelander, Sven

Part of Mathematical Biosciences, p. 75-81, 2016

• DOI for Travelling wave analysis of a mathematical model of glioblastoma growth

Origin of the U87MG glioma cell line: Good news and bad news

Allen, Marie; Bjerke, Mia; Edlund, Hanna; Nelander, Sven et al.

Part of Science Translational Medicine, 2016

• DOI for Origin of the U87MG glioma cell line: Good news and bad news

Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

Roy, Ananya; Coum, Antoine; Marinescu, Voichita D; Põlajeva, Jelena et al.

Part of Oncotarget, p. 23647-23661, 2015

• DOI for Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
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Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma

Swaminathan, Bhairavi; Thorleifsson, Guomar; Joud, Magnus; Ali, Mina et al.

Part of Nature Communications, 2015

• DOI for Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma
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High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes

Dijksterhuis, Jacomijn P.; Arthofer, Elisa; Marinescu, Voichita D.; Nelander, Sven et al.

Part of Experimental Cell Research, p. 280-288, 2015

• DOI for High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes

Efficient exploration of pan-cancer networks by generalized covariance selection and interactive web content

Kling, Teresia; Johansson, Patrik; Sanchez, Jose; Marinescu, Voichita D. et al.

Part of Nucleic Acids Research, 2015

• DOI for Efficient exploration of pan-cancer networks by generalized covariance selection and interactive web content
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Efficient exploration of multi-cancer networks by generalized covariance selection and interactive web content

Kling, Teresia; Johansson, Patrik; Sanchez, Jose; Marinescu, Voichita D. et al.

Part of Cancer Research, 2015

• DOI for Efficient exploration of multi-cancer networks by generalized covariance selection and interactive web content

Avoiding pitfalls in L-1-regularised inference of gene networks

Tjarnberg, Andreas; Nordling, Torbjörn E. M.; Studham, Matthew; Nelander, Sven et al.

Part of Molecular Biosystems, p. 287-296, 2015

• DOI for Avoiding pitfalls in L-1-regularised inference of gene networks

The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

Xie, Yuan; Bergström, Tobias; Jiang, Yiwen; Johansson, Patrik et al.

Part of EBioMedicine, p. 1351-1363, 2015

• DOI for The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes
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Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells

Wee, Shimei; Niklasson, Maria; Marinescu, Voichita Dana; Segerman, Anna et al.

Part of PLOS ONE, 2014

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Meta-Analysis of Neural Childhood Cancer Networks

Olsson, Maja; Kling, Teresia; Nelander, Sven

Part of Neuro-Oncology, p. 140-140, 2014

Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

Kitambi, Satish Srinivas; Toledo, Enrique M.; Usoskin, Dmitry; Wee, Shimei et al.

Part of Cell, p. 313-328, 2014

• DOI for Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

Functional association networks as priors for gene regulatory network inference

Studham, Matthew E.; Tjarnberg, Andreas; Nordling, Torbjörn; Nelander, Sven et al.

Part of Bioinformatics, p. 130-138, 2014

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Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening

Gerlee, Philip; Schmidt, Linnea; Monsefi, Naser; Kling, Teresia et al.

Part of PLOS ONE, 2013

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Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions

Schmidt, Linnea; Kling, Teresia; Monsefi, Naser; Olsson, Maja et al.

Part of Neuro-Oncology, p. 1469-1478, 2013

• DOI for Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions

Bridging the gaps in systems biology

Cvijovic, Marija; Almquist, Joachim; Hagmar, Jonas; Hohmann, Stefan et al.

Part of Molecular Genetics and Genomics, p. 727-734, 2014

• DOI for Bridging the gaps in systems biology

Identification of Biomarkers and Signatures in Protein Data

Nordling, Torbjörn E. M.; Padhan, Narendra; Nelander, Sven; Claesson-Welsh, Lena

Part of 2015 IEEE 11Th International Conference On E-Science, p. 411-419, 2015

• DOI for Identification of Biomarkers and Signatures in Protein Data

Exploring large scale integrative networks of glioblastoma using hypothesis driven pattern search

Johansson, Patrik; Rosén, Emil; Weishaupt, Holger; Jörnsten, Rebecka et al.

Decoding glioblastoma drug responses using an open access library of patient derived cell models

Johansson, Patrik; Schmidt, Linnéa; Baskaran, Sathishkumar; Kundu, Soumi et al.

Prioritization of candidate cancer genes on chromosome 17q through reverse engineered transcriptional regulatory networks in medulloblastoma groups 3 and 4

Weishaupt, Holger; Johansson, Patrik; Mainwaring, Oliver; Hutter, Sonja et al.

Targeting SOX2 in glioblastoma cells reveals heterogeneity in SOX2 dependency

Dalmo, Erika; Rosén, Gabriela; Niklasson, Mia; Bergström, Tobias et al.

The tumour microenvironment across tumour evolution in bladder cancer profiled by single-cell RNA-sequencing analysis and spatial transcriptomics

Kostakis, Alexandros; Beháňová, Andrea; Kyriaki Kerzeli, Iliana; Elgendy, Ramy et al.