Sven Nelander

Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts

Almstedt, Elin; Rosén, Emil; Gloger, Marleen; Rebecka, Stockard et al.

Part of Neuro-Oncology, p. 726-738, 2021

• DOI for Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
• Download full text (pdf) of Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts

Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

Kerzeli, Iliana Kyriaki; Lord, Martin; Doroszko, Milena; Elgendy, Ramy et al.

Part of PLOS ONE, 2021

• DOI for Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
• Download full text (pdf) of Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma

Vinel, Claire; Rosser, Gabriel; Guglielmi, Loredana; Constantinou, Myrianni et al.

Part of Nature Communications, 2021

• DOI for Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
• Download full text (pdf) of Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma

Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Lundin, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Part of Molecular Systems Biology, 2021

• DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
• Download full text (pdf) of Modeling glioblastoma heterogeneity as a dynamic network of cell states

A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

Johansson, Patrik; Krona, Cecilia; Kundu, Soumi; Doroszko, Milena et al.

Part of Cell Reports, 2020

• DOI for A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
• Download full text (pdf) of A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

Integrative discovery of treatments for high-risk neuroblastoma

Almstedt, Elin; Elgendy, Ramy; Hekmati, Neda; Rosén, Emil et al.

Part of Nature Communications, 2020

• DOI for Integrative discovery of treatments for high-risk neuroblastoma
• Download full text (pdf) of Integrative discovery of treatments for high-risk neuroblastoma

HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment

Johard, Helena; Omelyanenko, Anna; Fei, Gao; Zilberter, Misha et al.

Part of Molecular Cancer Research, p. 1522-1533, 2020

• DOI for HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment

BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Cancer, Matko; Drews, Lisa F.; Bengtsson, Johan; Bolin, Sara et al.

Part of Cell Death and Disease, 2019

• DOI for BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
• Download full text (pdf) of BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Xie, Yuan; Sundström, Anders; Maturi, Naga P; Tan, E-Jean et al.

Part of Journal of Pathology, p. 228-240, 2019

• DOI for LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

Baskaran, Sathishkumar; Mayrhofer, Markus; Göransson Kultima, Hanna; Bergström, Tobias et al.

Part of Neuro-Oncology, p. 1080-1091, 2018

• DOI for Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
• Download full text (pdf) of Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin

Jiang, Yiwen; Marinescu, Voichita Dana; Xie, Yuan; Jarvius, Malin et al.

Part of Cell Reports, p. 977-990, 2017

• DOI for Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
• Download full text (pdf) of Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin

Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers

Larsson, Ida; Held, Felix; Popova, Gergana; Koc, Alper et al.

Part of Nature Communications, 2024

• DOI for Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers
• Download full text (pdf) of Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers

Lineage specification in glioblastoma is regulated by METTL7B

Constantinou, Myrianni; Nicholson, James; Zhang, Xinyu; Maniati, Eleni et al.

Part of Cell Reports, 2024

• DOI for Lineage specification in glioblastoma is regulated by METTL7B
• Download full text (pdf) of Lineage specification in glioblastoma is regulated by METTL7B

Inference of glioblastoma migration and proliferation rates using single time-point images

Rosén, Emil; Mangukiya, Hitesh; Elfineh, Lioudmila; Stockgard, Rebecka et al.

Part of Communications Biology, 2023

• DOI for Inference of glioblastoma migration and proliferation rates using single time-point images
• Download full text (pdf) of Inference of glioblastoma migration and proliferation rates using single time-point images

Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

Ilkhanizadeh, Shirin; Gracias, Aileen; Aslund, Andreas K. O.; Back, Marcus et al.

Part of ACS Applied Bio Materials, p. 3790-3797, 2023

• DOI for Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
• Download full text (pdf) of Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

Knowledge of the perturbation design is essential for accurate gene regulatory network inference

Secilmis, Deniz; Hillerton, Thomas; Tjärnberg, Andreas; Nelander, Sven et al.

Part of Scientific Reports, 2022

• DOI for Knowledge of the perturbation design is essential for accurate gene regulatory network inference
• Download full text (pdf) of Knowledge of the perturbation design is essential for accurate gene regulatory network inference

Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers

Larsson, Ida; Held, Felix; Popova, Gergana; Koc, Alper et al.

Part of Nature Communications, 2024

• DOI for Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers
• Download full text (pdf) of Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers

Lineage specification in glioblastoma is regulated by METTL7B

Constantinou, Myrianni; Nicholson, James; Zhang, Xinyu; Maniati, Eleni et al.

Part of Cell Reports, 2024

• DOI for Lineage specification in glioblastoma is regulated by METTL7B
• Download full text (pdf) of Lineage specification in glioblastoma is regulated by METTL7B

Inference of glioblastoma migration and proliferation rates using single time-point images

Rosén, Emil; Mangukiya, Hitesh; Elfineh, Lioudmila; Stockgard, Rebecka et al.

Part of Communications Biology, 2023

• DOI for Inference of glioblastoma migration and proliferation rates using single time-point images
• Download full text (pdf) of Inference of glioblastoma migration and proliferation rates using single time-point images

Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

Ilkhanizadeh, Shirin; Gracias, Aileen; Aslund, Andreas K. O.; Back, Marcus et al.

Part of ACS Applied Bio Materials, p. 3790-3797, 2023

• DOI for Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
• Download full text (pdf) of Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

Knowledge of the perturbation design is essential for accurate gene regulatory network inference

Secilmis, Deniz; Hillerton, Thomas; Tjärnberg, Andreas; Nelander, Sven et al.

Part of Scientific Reports, 2022

• DOI for Knowledge of the perturbation design is essential for accurate gene regulatory network inference
• Download full text (pdf) of Knowledge of the perturbation design is essential for accurate gene regulatory network inference

Fast and accurate gene regulatory network inference by normalized least squares regression

Hillerton, Thomas; Secilmi, Deniz; Nelander, Sven; Sonnhammer, Erik L. L. et al.

Part of Bioinformatics, p. 2263-2268, 2022

• DOI for Fast and accurate gene regulatory network inference by normalized least squares regression
• Download full text (pdf) of Fast and accurate gene regulatory network inference by normalized least squares regression

Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape

Boot, James; Rosser, Gabriel; Kancheva, Dailya; Vinel, Claire et al.

Part of eLIFE, 2022

• DOI for Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape
• Download full text (pdf) of Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape

Optimal Sparsity Selection Based on an Information Criterion for Accurate Gene Regulatory Network Inference

Secilmis, Deniz; Nelander, Sven; Sonnhammer, Erik L. L.

Part of Frontiers in Genetics, 2022

• DOI for Optimal Sparsity Selection Based on an Information Criterion for Accurate Gene Regulatory Network Inference
• Download full text (pdf) of Optimal Sparsity Selection Based on an Information Criterion for Accurate Gene Regulatory Network Inference

MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner

Castell, Alina; Yan, Qinzi; Fawkner, Karin; Bazzar, Wesam et al.

Part of Cancer Research Communications, p. 182-201, 2022

• DOI for MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner
• Download full text (pdf) of MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner

Autocrine signaling can explain the emergence of Allee effects in cancer cell populations

Gerlee, Philip; Altrock, Philipp M.; Malik, Adam; Krona, Cecilia et al.

Part of PloS Computational Biology, 2022

• DOI for Autocrine signaling can explain the emergence of Allee effects in cancer cell populations
• Download full text (pdf) of Autocrine signaling can explain the emergence of Allee effects in cancer cell populations

Inferring the experimental design for accurate gene regulatory network inference

Secilmis, Deniz; Hillerton, Thomas; Nelander, Sven; Sonnhammer, Erik L. L.

Part of Bioinformatics, p. 3553-3559, 2021

• DOI for Inferring the experimental design for accurate gene regulatory network inference
• Download full text (pdf) of Inferring the experimental design for accurate gene regulatory network inference

p53-Mediated Radiosensitization of ¹⁷⁷Lu-DOTATATE in Neuroblastoma Tumor Spheroids

Lundsten, Sara; Berglund, Hanna; Jha, Preeti; Krona, Cecilia et al.

Part of Biomolecules, 2021

• DOI for p53-Mediated Radiosensitization of ¹⁷⁷Lu-DOTATATE in Neuroblastoma Tumor Spheroids
• Download full text (pdf) of p53-Mediated Radiosensitization of ¹⁷⁷Lu-DOTATATE in Neuroblastoma Tumor Spheroids

Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts

Almstedt, Elin; Rosén, Emil; Gloger, Marleen; Rebecka, Stockard et al.

Part of Neuro-Oncology, p. 726-738, 2021

• DOI for Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
• Download full text (pdf) of Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts

Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

Kerzeli, Iliana Kyriaki; Lord, Martin; Doroszko, Milena; Elgendy, Ramy et al.

Part of PLOS ONE, 2021

• DOI for Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
• Download full text (pdf) of Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

NF1 regulates mesenchymal gliblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

Marques, Carolina; Unterkircher, Thomas; Kroon, Paula; Oldrini, Barbara et al.

Part of eLIFE, 2021

• DOI for NF1 regulates mesenchymal gliblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
• Download full text (pdf) of NF1 regulates mesenchymal gliblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma

Vinel, Claire; Rosser, Gabriel; Guglielmi, Loredana; Constantinou, Myrianni et al.

Part of Nature Communications, 2021

• DOI for Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
• Download full text (pdf) of Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma

Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Lundin, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Part of Molecular Systems Biology, 2021

• DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
• Download full text (pdf) of Modeling glioblastoma heterogeneity as a dynamic network of cell states

Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Dalmo, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Part of Molecular Systems Biology, 2021

Uncovering cancer gene regulation by accurate regulatory network inference from uninformative data

Secilmis, Deniz; Hillerton, Thomas; Morgan, Daniel; Tjärnberg, Andreas et al.

Part of npj Systems Biology and Applications, 2020

• DOI for Uncovering cancer gene regulation by accurate regulatory network inference from uninformative data
• Download full text (pdf) of Uncovering cancer gene regulation by accurate regulatory network inference from uninformative data

A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

Johansson, Patrik; Krona, Cecilia; Kundu, Soumi; Doroszko, Milena et al.

Part of Cell Reports, 2020

• DOI for A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
• Download full text (pdf) of A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

Integrative discovery of treatments for high-risk neuroblastoma

Almstedt, Elin; Elgendy, Ramy; Hekmati, Neda; Rosén, Emil et al.

Part of Nature Communications, 2020

• DOI for Integrative discovery of treatments for high-risk neuroblastoma
• Download full text (pdf) of Integrative discovery of treatments for high-risk neuroblastoma

Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

Dalmo, Erika; Johansson, Patrik; Niklasson, Mia; Gustavsson, Ida et al.

Part of Molecular Cancer Research, p. 981-991, 2020

• DOI for Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma

Merisaari, Joni; Denisova, Oxana; Doroszko, Milena; Le Joncour, Vadim et al.

Part of Brain Communications, 2020

• DOI for Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma
• Download full text (pdf) of Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma

Astrocytes enhance glioblastoma growth.

Mega, Alessandro; Hartmark Nilsen, Mette; Leiss, Lina Wik; Tobin, Nicholas P et al.

Part of Glia, p. 316-327, 2020

• DOI for Astrocytes enhance glioblastoma growth.

HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment

Johard, Helena; Omelyanenko, Anna; Fei, Gao; Zilberter, Misha et al.

Part of Molecular Cancer Research, p. 1522-1533, 2020

• DOI for HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment

BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Cancer, Matko; Drews, Lisa F.; Bengtsson, Johan; Bolin, Sara et al.

Part of Cell Death and Disease, 2019

• DOI for BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
• Download full text (pdf) of BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Increasing the accuracy of glioblastoma subtypes: Factoring in the tumor's cell of origin

Nelander, Sven

Part of Molecular & Cellular Oncology, 2019

• DOI for Increasing the accuracy of glioblastoma subtypes: Factoring in the tumor's cell of origin
• Download full text (pdf) of Increasing the accuracy of glioblastoma subtypes: Factoring in the tumor's cell of origin

LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Xie, Yuan; Sundström, Anders; Maturi, Naga P; Tan, E-Jean et al.

Part of Journal of Pathology, p. 228-240, 2019

• DOI for LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Integrin alpha 10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival

Thoren, Matilda Munksgaard; Masoumi, Katarzyna Chmielarska; Krona, Cecilia; Huang, Xiaoli et al.

Part of Cancers, 2019

• DOI for Integrin alpha 10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival
• Download full text (pdf) of Integrin alpha 10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival

Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes

Weishaupt, Holger; Johansson, Patrik; Sundström, Anders; Lubovac-Pilav, Zelmina et al.

Part of Bioinformatics, p. 3357-3364, 2019

• DOI for Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes
• Download full text (pdf) of Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes

Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors

Kaffes, Ioannis; Szulzewsky, Frank; Chen, Zhihong; Herting, Cameron J. et al.

Part of Oncoimmunology, 2019

• DOI for Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
• Download full text (pdf) of Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors

Image-Based Detection of Patient-Specific Drug-Induced Cell-Cycle Effects in Glioblastoma

Matuszewski, Damian J.; Wählby, Carolina; Krona, Cecilia; Nelander, Sven et al.

Part of SLAS Discovery, p. 1030-1039, 2018

• DOI for Image-Based Detection of Patient-Specific Drug-Induced Cell-Cycle Effects in Glioblastoma

Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

Baskaran, Sathishkumar; Mayrhofer, Markus; Göransson Kultima, Hanna; Bergström, Tobias et al.

Part of Neuro-Oncology, p. 1080-1091, 2018

• DOI for Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
• Download full text (pdf) of Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin

Jiang, Yiwen; Marinescu, Voichita Dana; Xie, Yuan; Jarvius, Malin et al.

Part of Cell Reports, p. 977-990, 2017

• DOI for Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
• Download full text (pdf) of Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin

c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

Heiland, Dieter H.; Ferrarese, Roberto; Claus, Rainer; Dai, Fangping et al.

Part of Oncotarget, p. 6940-6954, 2017

• DOI for c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Ramachandran, Mohanraj; Yu, Di; Dyczynski, Matheus; Baskaran, Sathishkumar et al.

Part of Clinical Cancer Research, p. 1519-1530, 2017

• DOI for Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks

Weishaupt, Holger; Johansson, Patrik; Engström, Christopher; Nelander, Sven et al.

Part of Methodology and Computing in Applied Probability, p. 1089-1105, 2017

• DOI for Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks
• Download full text (pdf) of Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks

FC1000: normalized gene expression changes of systematically perturbed human cells

Lönnstedt, Ingrid M.; Nelander, Sven

Part of Statistical Applications in Genetics and Molecular Biology, p. 217-242, 2017

• DOI for FC1000: normalized gene expression changes of systematically perturbed human cells
• Download full text (pdf) of FC1000: normalized gene expression changes of systematically perturbed human cells

Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression

Fedele, Vita; Dai, Fangping; Masilamani, Anie P.; Heiland, Dieter H. et al.

Part of Molecular Cancer Research, p. 998-1011, 2017

• DOI for Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses

Niklasson, Mia; Maddalo, Gianluca; Sramkova, Zuzana; Mutlu, Ercan et al.

Part of Cancer Research, p. 1741-1752, 2017

• DOI for Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses

Case-specific potentiation of glioblastoma drugs by pterostilbene

Schmidt, Linnéa; Baskaran, Sathishkumar; Johansson, Patrik; Padhan, Narendra et al.

Part of Oncotarget, p. 73200-73215, 2016

• DOI for Case-specific potentiation of glioblastoma drugs by pterostilbene

High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

Padhan, Narendra; Nordling, Torbjorn E. M.; Sundström, Magnus; Åkerud, Peter et al.

Part of BMC Cancer, 2016

• DOI for High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer
• Download full text (pdf) of High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Darmanis, Spyros; Gallant, Caroline Julie; Marinescu, Voichita Dana; Niklasson, Mia et al.

Part of Cell Reports, p. 380-389, 2016

• DOI for Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
• Download full text (pdf) of Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Genome-wide association study identifies multiple susceptibility loci for multiple myeloma

Mitchell, Jonathan S.; Li, Ni; Weinhold, Niels; Försti, Asta et al.

Part of Nature Communications, 2016

• DOI for Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
• Download full text (pdf) of Genome-wide association study identifies multiple susceptibility loci for multiple myeloma

ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells

Wee, Boyoung; Pietras, Alexander; Ozawa, Tatsuya; Bazzoli, Elena et al.

Part of Scientific Reports, 2016

• DOI for ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells
• Download full text (pdf) of ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells

Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma

Kling, Teresia; Ferrarese, Roberto; Ailin, Darren Oh; Johansson, Patrik et al.

Part of EBioMedicine, p. 72-85, 2016

• DOI for Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma
• Download full text (pdf) of Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma

Travelling wave analysis of a mathematical model of glioblastoma growth

Gerlee, Philip; Nelander, Sven

Part of Mathematical Biosciences, p. 75-81, 2016

• DOI for Travelling wave analysis of a mathematical model of glioblastoma growth

Origin of the U87MG glioma cell line: Good news and bad news

Allen, Marie; Bjerke, Mia; Edlund, Hanna; Nelander, Sven et al.

Part of Science Translational Medicine, 2016

• DOI for Origin of the U87MG glioma cell line: Good news and bad news

Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

Roy, Ananya; Coum, Antoine; Marinescu, Voichita D; Põlajeva, Jelena et al.

Part of Oncotarget, p. 23647-23661, 2015

• DOI for Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
• Download full text (pdf) of Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma

Swaminathan, Bhairavi; Thorleifsson, Guomar; Joud, Magnus; Ali, Mina et al.

Part of Nature Communications, 2015

• DOI for Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma
• Download full text (pdf) of Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma

High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes

Dijksterhuis, Jacomijn P.; Arthofer, Elisa; Marinescu, Voichita D.; Nelander, Sven et al.

Part of Experimental Cell Research, p. 280-288, 2015

• DOI for High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes

The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

Xie, Yuan; Bergström, Tobias; Jiang, Yiwen; Johansson, Patrik et al.

Part of EBioMedicine, p. 1351-1363, 2015

• DOI for The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes
• Download full text (pdf) of The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

Efficient exploration of multi-cancer networks by generalized covariance selection and interactive web content

Kling, Teresia; Johansson, Patrik; Sanchez, Jose; Marinescu, Voichita D. et al.

Part of Cancer Research, 2015

• DOI for Efficient exploration of multi-cancer networks by generalized covariance selection and interactive web content

Efficient exploration of pan-cancer networks by generalized covariance selection and interactive web content

Kling, Teresia; Johansson, Patrik; Sanchez, Jose; Marinescu, Voichita D. et al.

Part of Nucleic Acids Research, 2015

• DOI for Efficient exploration of pan-cancer networks by generalized covariance selection and interactive web content
• Download full text (pdf) of Efficient exploration of pan-cancer networks by generalized covariance selection and interactive web content

Avoiding pitfalls in L-1-regularised inference of gene networks

Tjarnberg, Andreas; Nordling, Torbjörn E. M.; Studham, Matthew; Nelander, Sven et al.

Part of Molecular Biosystems, p. 287-296, 2015

• DOI for Avoiding pitfalls in L-1-regularised inference of gene networks

Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells

Wee, Shimei; Niklasson, Maria; Marinescu, Voichita Dana; Segerman, Anna et al.

Part of PLOS ONE, 2014

• DOI for Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells
• Download full text (pdf) of Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells

Functional association networks as priors for gene regulatory network inference

Studham, Matthew E.; Tjarnberg, Andreas; Nordling, Torbjörn; Nelander, Sven et al.

Part of Bioinformatics, p. 130-138, 2014

• DOI for Functional association networks as priors for gene regulatory network inference
• Download full text (pdf) of Functional association networks as priors for gene regulatory network inference

Meta-Analysis of Neural Childhood Cancer Networks

Olsson, Maja; Kling, Teresia; Nelander, Sven

Part of Neuro-Oncology, p. 140-140, 2014

Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

Kitambi, Satish Srinivas; Toledo, Enrique M.; Usoskin, Dmitry; Wee, Shimei et al.

Part of Cell, p. 313-328, 2014

• DOI for Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening

Gerlee, Philip; Schmidt, Linnea; Monsefi, Naser; Kling, Teresia et al.

Part of PLOS ONE, 2013

• DOI for Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening
• Download full text (pdf) of Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening

Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions

Schmidt, Linnea; Kling, Teresia; Monsefi, Naser; Olsson, Maja et al.

Part of Neuro-Oncology, p. 1469-1478, 2013

• DOI for Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions

Bridging the gaps in systems biology

Cvijovic, Marija; Almquist, Joachim; Hagmar, Jonas; Hohmann, Stefan et al.

Part of Molecular Genetics and Genomics, p. 727-734, 2014

• DOI for Bridging the gaps in systems biology

Identification of Biomarkers and Signatures in Protein Data

Nordling, Torbjörn E. M.; Padhan, Narendra; Nelander, Sven; Claesson-Welsh, Lena

Part of 2015 IEEE 11Th International Conference On E-Science, p. 411-419, 2015

• DOI for Identification of Biomarkers and Signatures in Protein Data

Exploring large scale integrative networks of glioblastoma using hypothesis driven pattern search

Johansson, Patrik; Rosén, Emil; Weishaupt, Holger; Jörnsten, Rebecka et al.

Decoding glioblastoma drug responses using an open access library of patient derived cell models

Johansson, Patrik; Schmidt, Linnéa; Baskaran, Sathishkumar; Kundu, Soumi et al.

Prioritization of candidate cancer genes on chromosome 17q through reverse engineered transcriptional regulatory networks in medulloblastoma groups 3 and 4

Weishaupt, Holger; Johansson, Patrik; Mainwaring, Oliver; Hutter, Sonja et al.

Targeting SOX2 in glioblastoma cells reveals heterogeneity in SOX2 dependency

Dalmo, Erika; Rosén, Gabriela; Niklasson, Mia; Bergström, Tobias et al.

The tumour microenvironment across tumour evolution in bladder cancer profiled by single-cell RNA-sequencing analysis and spatial transcriptomics

Kostakis, Alexandros; Beháňová, Andrea; Kyriaki Kerzeli, Iliana; Elgendy, Ramy et al.