Sven Nelander
- E-mail:
- sven.nelander@igp.uu.se
- Visiting address:
- Dag Hammarskjölds väg 20
751 85 Uppsala - Postal address:
- Rudbecklaboratoriet
751 85 UPPSALA

Publications
Selection of publications
Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
Part of Neuro-Oncology, p. 726-738, 2021
- DOI for Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
- Download full text (pdf) of Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
Part of PLOS ONE, 2021
- DOI for Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
- Download full text (pdf) of Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
Part of Nature Communications, 2021
- DOI for Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
- Download full text (pdf) of Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
Modeling glioblastoma heterogeneity as a dynamic network of cell states
Part of Molecular Systems Biology, 2021
- DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
- Download full text (pdf) of Modeling glioblastoma heterogeneity as a dynamic network of cell states
A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
Part of Cell Reports, 2020
- DOI for A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
- Download full text (pdf) of A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
Integrative discovery of treatments for high-risk neuroblastoma
Part of Nature Communications, 2020
- DOI for Integrative discovery of treatments for high-risk neuroblastoma
- Download full text (pdf) of Integrative discovery of treatments for high-risk neuroblastoma
Part of Molecular Cancer Research, p. 1522-1533, 2020
BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
Part of Cell Death and Disease, 2019
- DOI for BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
- Download full text (pdf) of BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
Part of Journal of Pathology, p. 228-240, 2019
Part of Neuro-Oncology, p. 1080-1091, 2018
- DOI for Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
- Download full text (pdf) of Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
Part of Cell Reports, p. 977-990, 2017
- DOI for Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
- Download full text (pdf) of Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
Recent publications
Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers
Part of Nature Communications, 2024
- DOI for Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers
- Download full text (pdf) of Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers
Lineage specification in glioblastoma is regulated by METTL7B
Part of Cell Reports, 2024
- DOI for Lineage specification in glioblastoma is regulated by METTL7B
- Download full text (pdf) of Lineage specification in glioblastoma is regulated by METTL7B
Inference of glioblastoma migration and proliferation rates using single time-point images
Part of Communications Biology, 2023
- DOI for Inference of glioblastoma migration and proliferation rates using single time-point images
- Download full text (pdf) of Inference of glioblastoma migration and proliferation rates using single time-point images
Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
Part of ACS Applied Bio Materials, p. 3790-3797, 2023
- DOI for Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
- Download full text (pdf) of Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
Knowledge of the perturbation design is essential for accurate gene regulatory network inference
Part of Scientific Reports, 2022
- DOI for Knowledge of the perturbation design is essential for accurate gene regulatory network inference
- Download full text (pdf) of Knowledge of the perturbation design is essential for accurate gene regulatory network inference
All publications
Articles in journal
Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers
Part of Nature Communications, 2024
- DOI for Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers
- Download full text (pdf) of Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers
Lineage specification in glioblastoma is regulated by METTL7B
Part of Cell Reports, 2024
- DOI for Lineage specification in glioblastoma is regulated by METTL7B
- Download full text (pdf) of Lineage specification in glioblastoma is regulated by METTL7B
Inference of glioblastoma migration and proliferation rates using single time-point images
Part of Communications Biology, 2023
- DOI for Inference of glioblastoma migration and proliferation rates using single time-point images
- Download full text (pdf) of Inference of glioblastoma migration and proliferation rates using single time-point images
Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
Part of ACS Applied Bio Materials, p. 3790-3797, 2023
- DOI for Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
- Download full text (pdf) of Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
Knowledge of the perturbation design is essential for accurate gene regulatory network inference
Part of Scientific Reports, 2022
- DOI for Knowledge of the perturbation design is essential for accurate gene regulatory network inference
- Download full text (pdf) of Knowledge of the perturbation design is essential for accurate gene regulatory network inference
Fast and accurate gene regulatory network inference by normalized least squares regression
Part of Bioinformatics, p. 2263-2268, 2022
- DOI for Fast and accurate gene regulatory network inference by normalized least squares regression
- Download full text (pdf) of Fast and accurate gene regulatory network inference by normalized least squares regression
Part of eLIFE, 2022
- DOI for Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape
- Download full text (pdf) of Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape
Part of Frontiers in Genetics, 2022
- DOI for Optimal Sparsity Selection Based on an Information Criterion for Accurate Gene Regulatory Network Inference
- Download full text (pdf) of Optimal Sparsity Selection Based on an Information Criterion for Accurate Gene Regulatory Network Inference
Part of Cancer Research Communications, p. 182-201, 2022
- DOI for MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner
- Download full text (pdf) of MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner
Autocrine signaling can explain the emergence of Allee effects in cancer cell populations
Part of PloS Computational Biology, 2022
- DOI for Autocrine signaling can explain the emergence of Allee effects in cancer cell populations
- Download full text (pdf) of Autocrine signaling can explain the emergence of Allee effects in cancer cell populations
Inferring the experimental design for accurate gene regulatory network inference
Part of Bioinformatics, p. 3553-3559, 2021
- DOI for Inferring the experimental design for accurate gene regulatory network inference
- Download full text (pdf) of Inferring the experimental design for accurate gene regulatory network inference
p53-Mediated Radiosensitization of 177Lu-DOTATATE in Neuroblastoma Tumor Spheroids
Part of Biomolecules, 2021
- DOI for p53-Mediated Radiosensitization of 177Lu-DOTATATE in Neuroblastoma Tumor Spheroids
- Download full text (pdf) of p53-Mediated Radiosensitization of 177Lu-DOTATATE in Neuroblastoma Tumor Spheroids
Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
Part of Neuro-Oncology, p. 726-738, 2021
- DOI for Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
- Download full text (pdf) of Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
Part of PLOS ONE, 2021
- DOI for Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
- Download full text (pdf) of Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
Part of eLIFE, 2021
- DOI for NF1 regulates mesenchymal gliblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
- Download full text (pdf) of NF1 regulates mesenchymal gliblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
Part of Nature Communications, 2021
- DOI for Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
- Download full text (pdf) of Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
Modeling glioblastoma heterogeneity as a dynamic network of cell states
Part of Molecular Systems Biology, 2021
- DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
- Download full text (pdf) of Modeling glioblastoma heterogeneity as a dynamic network of cell states
Modeling glioblastoma heterogeneity as a dynamic network of cell states
Part of Molecular Systems Biology, 2021
Uncovering cancer gene regulation by accurate regulatory network inference from uninformative data
Part of npj Systems Biology and Applications, 2020
- DOI for Uncovering cancer gene regulation by accurate regulatory network inference from uninformative data
- Download full text (pdf) of Uncovering cancer gene regulation by accurate regulatory network inference from uninformative data
A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
Part of Cell Reports, 2020
- DOI for A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
- Download full text (pdf) of A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
Integrative discovery of treatments for high-risk neuroblastoma
Part of Nature Communications, 2020
- DOI for Integrative discovery of treatments for high-risk neuroblastoma
- Download full text (pdf) of Integrative discovery of treatments for high-risk neuroblastoma
Part of Molecular Cancer Research, p. 981-991, 2020
Part of Brain Communications, 2020
- DOI for Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma
- Download full text (pdf) of Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma
Astrocytes enhance glioblastoma growth.
Part of Glia, p. 316-327, 2020
Part of Molecular Cancer Research, p. 1522-1533, 2020
BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
Part of Cell Death and Disease, 2019
- DOI for BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
- Download full text (pdf) of BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
Increasing the accuracy of glioblastoma subtypes: Factoring in the tumor's cell of origin
Part of Molecular & Cellular Oncology, 2019
- DOI for Increasing the accuracy of glioblastoma subtypes: Factoring in the tumor's cell of origin
- Download full text (pdf) of Increasing the accuracy of glioblastoma subtypes: Factoring in the tumor's cell of origin
Part of Journal of Pathology, p. 228-240, 2019
Part of Cancers, 2019
- DOI for Integrin alpha 10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival
- Download full text (pdf) of Integrin alpha 10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival
Part of Bioinformatics, p. 3357-3364, 2019
- DOI for Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes
- Download full text (pdf) of Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes
Part of Oncoimmunology, 2019
- DOI for Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
- Download full text (pdf) of Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
Image-Based Detection of Patient-Specific Drug-Induced Cell-Cycle Effects in Glioblastoma
Part of SLAS Discovery, p. 1030-1039, 2018
Part of Neuro-Oncology, p. 1080-1091, 2018
- DOI for Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
- Download full text (pdf) of Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
Part of Cell Reports, p. 977-990, 2017
- DOI for Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
- Download full text (pdf) of Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin
c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas
Part of Oncotarget, p. 6940-6954, 2017
Part of Clinical Cancer Research, p. 1519-1530, 2017
Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks
Part of Methodology and Computing in Applied Probability, p. 1089-1105, 2017
- DOI for Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks
- Download full text (pdf) of Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks
FC1000: normalized gene expression changes of systematically perturbed human cells
Part of Statistical Applications in Genetics and Molecular Biology, p. 217-242, 2017
- DOI for FC1000: normalized gene expression changes of systematically perturbed human cells
- Download full text (pdf) of FC1000: normalized gene expression changes of systematically perturbed human cells
Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression
Part of Molecular Cancer Research, p. 998-1011, 2017
Part of Cancer Research, p. 1741-1752, 2017
Case-specific potentiation of glioblastoma drugs by pterostilbene
Part of Oncotarget, p. 73200-73215, 2016
Part of BMC Cancer, 2016
- DOI for High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer
- Download full text (pdf) of High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer
Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
Part of Cell Reports, p. 380-389, 2016
- DOI for Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
- Download full text (pdf) of Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
Part of Nature Communications, 2016
- DOI for Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
- Download full text (pdf) of Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
Part of Scientific Reports, 2016
- DOI for ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells
- Download full text (pdf) of ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells
Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma
Part of EBioMedicine, p. 72-85, 2016
- DOI for Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma
- Download full text (pdf) of Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma
Travelling wave analysis of a mathematical model of glioblastoma growth
Part of Mathematical Biosciences, p. 75-81, 2016
Origin of the U87MG glioma cell line: Good news and bad news
Part of Science Translational Medicine, 2016
Part of Oncotarget, p. 23647-23661, 2015
- DOI for Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
- Download full text (pdf) of Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma
Part of Nature Communications, 2015
- DOI for Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma
- Download full text (pdf) of Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma
Part of Experimental Cell Research, p. 280-288, 2015
Part of EBioMedicine, p. 1351-1363, 2015
- DOI for The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes
- Download full text (pdf) of The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes
Part of Cancer Research, 2015
Part of Nucleic Acids Research, 2015
- DOI for Efficient exploration of pan-cancer networks by generalized covariance selection and interactive web content
- Download full text (pdf) of Efficient exploration of pan-cancer networks by generalized covariance selection and interactive web content
Avoiding pitfalls in L-1-regularised inference of gene networks
Part of Molecular Biosystems, p. 287-296, 2015
Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells
Part of PLOS ONE, 2014
- DOI for Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells
- Download full text (pdf) of Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells
Functional association networks as priors for gene regulatory network inference
Part of Bioinformatics, p. 130-138, 2014
- DOI for Functional association networks as priors for gene regulatory network inference
- Download full text (pdf) of Functional association networks as priors for gene regulatory network inference
Meta-Analysis of Neural Childhood Cancer Networks
Part of Neuro-Oncology, p. 140-140, 2014
Part of Cell, p. 313-328, 2014
Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening
Part of PLOS ONE, 2013
- DOI for Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening
- Download full text (pdf) of Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening
Part of Neuro-Oncology, p. 1469-1478, 2013
Articles, review/survey
Bridging the gaps in systems biology
Part of Molecular Genetics and Genomics, p. 727-734, 2014
Conference papers
Identification of Biomarkers and Signatures in Protein Data
Part of 2015 IEEE 11Th International Conference On E-Science, p. 411-419, 2015