Pawel Baranczewski

Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Huseby, Douglas L.; Cao, Sha; Zamaratski, Edouard; Sooriyaarachchi, Sanjeewani et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI for Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
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Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project

Nordeng, Hedvig; Wegler, Christine; Lindqvist, Annika; Melander, Erik et al.

Part of Basic & Clinical Pharmacology & Toxicology, p. 153-164, 2024

• DOI for Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project
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Population pharmacokinetic modelling of cetirizine concentrations in human breast milk: A contribution from the ConcePTION project

Melander, Erik; Nielsen, Elisabet I.; Lindqvist, Annika; Hovd, Markus et al.

Part of Basic & Clinical Pharmacology & Toxicology, 2024

• DOI for Population pharmacokinetic modelling of cetirizine concentrations in human breast milk: A contribution from the ConcePTION project
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AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1

Díaz-Holguin, Alejandro; Saarinen, Marcus; Vo, Duc Duy; Sturchio, Andrea et al.

Part of Science Advances, 2024

• DOI for AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1
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Simple and rapid quantification of cetirizine, venlafaxine, and O-desmethylvenlafaxine in human breast milk, and metformin in human milk and plasma with UHPLC-MS/MS

Wegler, Christine; Saleh, Aljona; Lindqvist, Annika; Nordeng, Hedvig et al.

Part of Journal of chromatography. B, 2022

• DOI for Simple and rapid quantification of cetirizine, venlafaxine, and O-desmethylvenlafaxine in human breast milk, and metformin in human milk and plasma with UHPLC-MS/MS

Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Huseby, Douglas L.; Cao, Sha; Zamaratski, Edouard; Sooriyaarachchi, Sanjeewani et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI for Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
• Download full text (pdf) of Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project

Nordeng, Hedvig; Wegler, Christine; Lindqvist, Annika; Melander, Erik et al.

Part of Basic & Clinical Pharmacology & Toxicology, p. 153-164, 2024

• DOI for Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project
• Download full text (pdf) of Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project

Population pharmacokinetic modelling of cetirizine concentrations in human breast milk: A contribution from the ConcePTION project

Melander, Erik; Nielsen, Elisabet I.; Lindqvist, Annika; Hovd, Markus et al.

Part of Basic & Clinical Pharmacology & Toxicology, 2024

• DOI for Population pharmacokinetic modelling of cetirizine concentrations in human breast milk: A contribution from the ConcePTION project
• Download full text (pdf) of Population pharmacokinetic modelling of cetirizine concentrations in human breast milk: A contribution from the ConcePTION project

AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1

Díaz-Holguin, Alejandro; Saarinen, Marcus; Vo, Duc Duy; Sturchio, Andrea et al.

Part of Science Advances, 2024

• DOI for AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1
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Simple and rapid quantification of cetirizine, venlafaxine, and O-desmethylvenlafaxine in human breast milk, and metformin in human milk and plasma with UHPLC-MS/MS

Wegler, Christine; Saleh, Aljona; Lindqvist, Annika; Nordeng, Hedvig et al.

Part of Journal of chromatography. B, 2022

• DOI for Simple and rapid quantification of cetirizine, venlafaxine, and O-desmethylvenlafaxine in human breast milk, and metformin in human milk and plasma with UHPLC-MS/MS

Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

Brem, Jürgen; Panduwawala, Tharindi; Hansen, Jon Ulf; Hewitt, Joanne et al.

Part of Nature Chemistry, p. 15-24, 2022

• DOI for Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

ENABLE: an engine for European antibacterial drug discovery and development

Olliver, Marie; Griestop, Laura; Hughes, Diarmaid; Belfrage, Anna Karin et al.

Part of Nature reviews. Drug discovery, p. 407-408, 2021

• DOI for ENABLE: an engine for European antibacterial drug discovery and development

A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research

Matsson, Pär; Baranczewski, Pawel; Giacomini, Kathleen M.; Andersson, Tommy B. et al.

Part of Journal of Pharmaceutical Sciences, p. 2-11, 2021

• DOI for A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research

Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations

Filppula, Anne M.; Parvizi, Rezvan; Mateus, André; Baranczewski, Pawel et al.

Part of Scientific Reports, 2019

• DOI for Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations
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Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Page, Brent D. G.; Valerie, Nicholas C. K.; Wright, Roni H. G.; Wallner, Olov et al.

Part of Nature Communications, 2018

• DOI for Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
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Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound

Islam, Md. Koushikul; Strand, Mårten; Saleeb, Michael; Svensson, Richard et al.

Part of Scientific Reports, 2018

• DOI for Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound
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Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Visnes, Torkild; Cazares-Korner, Armando; Hao, Wenjing; Wallner, Olov et al.

Part of Science, p. 834-839, 2018

• DOI for Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Structure-metabolism-relationships in the microsomal clearance of piperazin-1-ylpyridazines

Llona-Minguez, Sabin; Ghassemian, Artin; Baranczewski, Pawel; Desroses, Matthieu et al.

Part of MedChemComm, p. 1553-1560, 2017

• DOI for Structure-metabolism-relationships in the microsomal clearance of piperazin-1-ylpyridazines

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1

Llona-Minguez, Sabin; Höglund, Andreas; Wiita, Elisee; Almlof, Ingrid et al.

Part of Journal of Medicinal Chemistry, p. 2148-2154, 2017

• DOI for Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

Llona-Minguez, Sabin; Höglund, Andreas; Ghassemian, Artin; Desroses, Matthieu et al.

Part of Journal of Medicinal Chemistry, p. 4279-4292, 2017

• DOI for Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

Validation and development of MTH1 inhibitors for treatment of cancer

Berglund, U. Warpman; Sanjiv, K.; Gad, H.; Kalderen, C. et al.

Part of Annals of Oncology, p. 2275-2283, 2016

• DOI for Validation and development of MTH1 inhibitors for treatment of cancer
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Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1

Llona-Minguez, Sabin; Höglund, Andreas; Jacques, Sylvain A.; Johanson, Lars et al.

Part of Journal of Medicinal Chemistry, p. 1140-1148, 2016

• DOI for Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Gad, Helge; Koolmeister, Tobias; Jemth, Ann-Sofie; Eshtad, Saeed et al.

Part of Nature, p. 215-221, 2014

• DOI for MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Assessment of interaction potential of AZD2066 using in vitro metabolism tools, physiologically based pharmacokinetic modelling and in vivo cocktail data

Nordmark, Anna; Andersson, Anita; Baranczewski, Pawel; Wanag, Ewa et al.

Part of European Journal of Clinical Pharmacology, p. 167-178, 2014

• DOI for Assessment of interaction potential of AZD2066 using in vitro metabolism tools, physiologically based pharmacokinetic modelling and in vivo cocktail data