Jyrki Tenhunen

Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach

van der Heijden, Jaap; Mazubane, Asanda; Sallisalmi, Marko; Vorontsov, Egor et al.

Part of Clinical Proteomics, 2025

• DOI for Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach
• Download full text (pdf) of Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach

The addition of lactate to SOFA score improves the prediction of mortality in patients with severe burns–A retrospective cohort study

Knave, Martin Huss; Elvihs, Romans; Tenhunen, Jyrki; Huss, Fredrik et al.

Part of Burns Open, p. 100398-100398, 2025

• DOI for The addition of lactate to SOFA score improves the prediction of mortality in patients with severe burns–A retrospective cohort study

Nordic physician-staffed prehospital services - organisation and preparedness for major emergency surgical procedures

Galos, Peter; Chevalley, Karl; Larsen, Robert; Sandstroem, Goeran et al.

Part of Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2025

• DOI for Nordic physician-staffed prehospital services - organisation and preparedness for major emergency surgical procedures
• Download full text (pdf) of Nordic physician-staffed prehospital services - organisation and preparedness for major emergency surgical procedures

High molecular weight hyaluronan - a potential adjuvant to fluid resuscitation in abdominal sepsis?

Barrueta Tenhunen, Annelie; van der Heijden, Jaap; Dogné, Sophie; Flamion, Bruno et al.

Part of Shock, p. 763-770, 2023

• DOI for High molecular weight hyaluronan - a potential adjuvant to fluid resuscitation in abdominal sepsis?
• Download full text (pdf) of High molecular weight hyaluronan - a potential adjuvant to fluid resuscitation in abdominal sepsis?

Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis

Barrueta Tenhunen, Annelie; van der Heijden, Jaap; Skorup, Paul; Maccarana, Marco et al.

Part of Intensive Care Medicine Experimental, 2023

• DOI for Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis
• Download full text (pdf) of Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis

Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach

van der Heijden, Jaap; Mazubane, Asanda; Sallisalmi, Marko; Vorontsov, Egor et al.

Part of Clinical Proteomics, 2025

• DOI for Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach
• Download full text (pdf) of Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach

The addition of lactate to SOFA score improves the prediction of mortality in patients with severe burns–A retrospective cohort study

Knave, Martin Huss; Elvihs, Romans; Tenhunen, Jyrki; Huss, Fredrik et al.

Part of Burns Open, p. 100398-100398, 2025

• DOI for The addition of lactate to SOFA score improves the prediction of mortality in patients with severe burns–A retrospective cohort study

Nordic physician-staffed prehospital services - organisation and preparedness for major emergency surgical procedures

Galos, Peter; Chevalley, Karl; Larsen, Robert; Sandstroem, Goeran et al.

Part of Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2025

• DOI for Nordic physician-staffed prehospital services - organisation and preparedness for major emergency surgical procedures
• Download full text (pdf) of Nordic physician-staffed prehospital services - organisation and preparedness for major emergency surgical procedures

High molecular weight hyaluronan - a potential adjuvant to fluid resuscitation in abdominal sepsis?

Barrueta Tenhunen, Annelie; van der Heijden, Jaap; Dogné, Sophie; Flamion, Bruno et al.

Part of Shock, p. 763-770, 2023

• DOI for High molecular weight hyaluronan - a potential adjuvant to fluid resuscitation in abdominal sepsis?
• Download full text (pdf) of High molecular weight hyaluronan - a potential adjuvant to fluid resuscitation in abdominal sepsis?

Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis

Barrueta Tenhunen, Annelie; van der Heijden, Jaap; Skorup, Paul; Maccarana, Marco et al.

Part of Intensive Care Medicine Experimental, 2023

• DOI for Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis
• Download full text (pdf) of Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis sepsis

Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis: an experimental and clinical cohort study

van der Heijden, Jaap; Kolliopoulos, Constantinos; Skorup, Paul; Sallisalmi, Marko et al.

Part of Intensive Care Medicine Experimental, 2021

• DOI for Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis: an experimental and clinical cohort study
• Download full text (pdf) of Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis: an experimental and clinical cohort study

Mono-(2-ethylhexyl) phthalate Promotes Dengue Virus Infection by Decreasing IL-23-Mediated Antiviral Responses

Lin, Chun-Yu; Huang, Chung-Hao; Wang, Wen-Hung; Tenhunen, Jyrki et al.

Part of Frontiers in Immunology, 2021

• DOI for Mono-(2-ethylhexyl) phthalate Promotes Dengue Virus Infection by Decreasing IL-23-Mediated Antiviral Responses
• Download full text (pdf) of Mono-(2-ethylhexyl) phthalate Promotes Dengue Virus Infection by Decreasing IL-23-Mediated Antiviral Responses

Never quite there?: Hyperventilation in cardiopulmonary resuscitation

Orlob, Simon; Wittig, Johannes; Tenhunen, Jyrki; Wnent, Jan et al.

Part of Resuscitation, p. 138-139, 2021

• DOI for Never quite there?: Hyperventilation in cardiopulmonary resuscitation

Plasma Hyaluronan Decreases During ICU Stay in COVID-19 Survivors but Not inNon-Survivor: A Retrospective Cohort Study

van der Heijden, Jaap; Kolliopoulos, Constantinos; Stattin, Karl; Lipcsey, Miklos et al.

Part of Biomarkers Journal, 2021

The antisecretory peptide AF-16 may modulate tissue edema but not inflammation in experimental peritonitis induced sepsis

Barrueta Tenhunen, Annelie; van der Heijden, Jaap; Blokhin, Ivan; Massaro, Fabrizia et al.

Part of PLOS ONE, 2020

• DOI for The antisecretory peptide AF-16 may modulate tissue edema but not inflammation in experimental peritonitis induced sepsis
• Download full text (pdf) of The antisecretory peptide AF-16 may modulate tissue edema but not inflammation in experimental peritonitis induced sepsis

Endotoxin removal in septic shock with the Alteco LPS adsorber was safe but showed no benefit compared to placebo in the double-blind randomized controlled trial-the asset study

Lipcsey, Miklós; Tenhunen, Jyrki; Pischke, Soeren E.; Kuitunen, Anne et al.

Part of Shock, p. 224-231, 2020

• DOI for Endotoxin removal in septic shock with the Alteco LPS adsorber was safe but showed no benefit compared to placebo in the double-blind randomized controlled trial-the asset study

High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrity

Lin, Chun-Yu; Kolliopoulos, Constantinos; Huang, Chung-Hao; Tenhunen, Jyrki et al.

Part of EBioMedicine, p. 425-441, 2019

• DOI for High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrity
• Download full text (pdf) of High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrity

S100B, NSE and MMP-9 fail to predict neurologic outcome while elevated S100B associates with milder initial clinical presentation after aneurysmal subarachnoid hemorrhage

Kiiski, Heikki; Långsjö, Jaakko; Tenhunen, Jyrki; Ala-Peijari, Marika et al.

Part of Journal of the Neurological Sciences, p. 129-134, 2018

• DOI for S100B, NSE and MMP-9 fail to predict neurologic outcome while elevated S100B associates with milder initial clinical presentation after aneurysmal subarachnoid hemorrhage

Good quality of life before cardiac arrest predicts good quality of life after resuscitation

Hellevuo, H.; Sainio, M.; Huhtala, H.; Olkkola, K. T. et al.

Part of Acta Anaesthesiologica Scandinavica, p. 515-521, 2018

• DOI for Good quality of life before cardiac arrest predicts good quality of life after resuscitation

Plasma soluble Urokinase-Type Plasminogen activator receptor is not associated with neurological Outcome in Patients with aneurysmal subarachnoid hemorrhage

Kiiski, Heikki; Jalkanen, Ville; Ala-Peijari, Marika; Hamalainen, Mari et al.

Part of Frontiers in Neurology, 2017

• DOI for Plasma soluble Urokinase-Type Plasminogen activator receptor is not associated with neurological Outcome in Patients with aneurysmal subarachnoid hemorrhage
• Download full text (pdf) of Plasma soluble Urokinase-Type Plasminogen activator receptor is not associated with neurological Outcome in Patients with aneurysmal subarachnoid hemorrhage

Successful management of super-refractory status epilepticus with thalamic deep brain stimulation

Kai, Lehtimaki; Jaakko, W. Langsjo; Jyrki, Ollikainen; Hanna, Heinonen et al.

Part of Annals of Neurology, p. 142-146, 2017

• DOI for Successful management of super-refractory status epilepticus with thalamic deep brain stimulation

Abdominal Septic Shock - Endotoxin Adsorption Treatment (ASSET) - endotoxin removal in abdominal and urogenital septic shock with the Alteco (R) LPS Adsorber: study protocol for a double-blinded, randomized placebo-controlled trial

Lipcsey, Miklós; Tenhunen, Jyrki; Sjölin, Jan; Frithiof, Robert et al.

Part of Trials, 2016

• DOI for Abdominal Septic Shock - Endotoxin Adsorption Treatment (ASSET) - endotoxin removal in abdominal and urogenital septic shock with the Alteco (R) LPS Adsorber: study protocol for a double-blinded, randomized placebo-controlled trial
• Download full text (pdf) of Abdominal Septic Shock - Endotoxin Adsorption Treatment (ASSET) - endotoxin removal in abdominal and urogenital septic shock with the Alteco (R) LPS Adsorber: study protocol for a double-blinded, randomized placebo-controlled trial

Increased plasma UCH-L1 after aneurysmal subarachnoid hemorrhage is associated with unfavorable neurological outcome

Kiiski, Heikki; Tenhunen, Jyrki; Ala-Peijari, Marika; Huhtala, Heini et al.

Part of Journal of the Neurological Sciences, p. 144-149, 2016

• DOI for Increased plasma UCH-L1 after aneurysmal subarachnoid hemorrhage is associated with unfavorable neurological outcome

Ethically justified treatment limitations in emergency situations

Tirkkonen, Joonas; Olkkola, Klaus T.; Tenhunen, Jyrki; Hoppu, Sanna

Part of European journal of emergency medicine, p. 214-218, 2016

• DOI for Ethically justified treatment limitations in emergency situations

Predictive value of urine interleukin-18 in the evolution and outcome of acute kidney injury in critically ill adult patients

Nisula, S.; Yang, R.; Poukkanen, M.; Vaara, S. T. et al.

Part of British Journal of Anaesthesia, p. 460-468, 2015

• DOI for Predictive value of urine interleukin-18 in the evolution and outcome of acute kidney injury in critically ill adult patients

Simultaneous beat-to-beat assessment of arterial blood pressure and quality of cardiopulmonary resuscitation in out-of-hospital and in-hospital settings

Sainio, Marko; Hoppu, Sanna; Huhtala, Heini; Eilevstjonn, Joar et al.

Part of Resuscitation, p. 163-169, 2015

• DOI for Simultaneous beat-to-beat assessment of arterial blood pressure and quality of cardiopulmonary resuscitation in out-of-hospital and in-hospital settings

HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicity

Yang, Runkuan; Zou, Xiaoping; Tenhunen, Jyrki; Zhu, Shengtao et al.

Part of BMC Gastroenterology, p. 66, 2014

• DOI for HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicity
• Download full text (pdf) of HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicity

Confined ischemia may improve remote myocardial outcome after rat cardiac arrest

Wang, Zanxin; Li, Hongyan; Vuohelainen, Vilma; Tenhunen, Jyrki et al.

Part of Scandinavian Journal of Clinical and Laboratory Investigation, p. 27-36, 2014

• DOI for Confined ischemia may improve remote myocardial outcome after rat cardiac arrest

Plasma hyaluronan and hemorheology in patients with septic shock: a clinical and experimental study

Sallisalmi, Marko; Tenhunen, Jyrki; Kultti, Anne; Tammi, Markku et al.

Part of Clinical hemorheology and microcirculation, p. 133-144, 2014

• DOI for Plasma hyaluronan and hemorheology in patients with septic shock: a clinical and experimental study

The quality of manual chest compressions during transport: effect of the mattress assessed by dual accelerometers

Hellevuo, H; Sainio, M; Huhtala, H; Olkkola, K T et al.

Part of Acta Anaesthesiologica Scandinavica, p. 323-328, 2014

• DOI for The quality of manual chest compressions during transport: effect of the mattress assessed by dual accelerometers

Cardiac arrest teams and medical emergency teams in Finland: a nationwide cross- sectional postal survey

Tirkkonen, J.; Nurmi, J.; Olkkola, K. T.; Tenhunen, Jyrki et al.

Part of Acta Anaesthesiologica Scandinavica, p. 420-427, 2014

• DOI for Cardiac arrest teams and medical emergency teams in Finland: a nationwide cross- sectional postal survey

Medical emergency team activation: performance of conventional dichotomised criteria versus national early warning score

Tirkkonen, Joonas; Olkkola, Klaus T.; Huhtala, Heini; Tenhunen, Jyrki et al.

Part of Acta Anaesthesiologica Scandinavica, p. 411-419, 2014

• DOI for Medical emergency team activation: performance of conventional dichotomised criteria versus national early warning score

Effect of mattress and bed frame deflection on real chest compression depth measured with two CPR sensors

Sainio, Marko; Hellevuo, Heidi; Huhtala, Heini; Hoppu, Sanna et al.

Part of Resuscitation, p. 840-843, 2014

• DOI for Effect of mattress and bed frame deflection on real chest compression depth measured with two CPR sensors

The Urine Protein NGAL Predicts Renal Replacement Therapy, but Not Acute Kidney Injury or 90-Day Mortality in Critically III Adult Patients

Nisula, Sara; Yang, Runkuan; Kaukonen, Kirsi-Maija; Vaara, Suvi T. et al.

Part of Anesthesia and Analgesia, p. 95-102, 2014

• DOI for The Urine Protein NGAL Predicts Renal Replacement Therapy, but Not Acute Kidney Injury or 90-Day Mortality in Critically III Adult Patients

Long-term outcomes in patients with severe sepsis randomised to resuscitation with hydroxyethyl starch 130/0.42 or Ringer's acetate

Perner, Anders; Haase, Nicolai; Winkel, Per; Guttormsen, Anne B. et al.

Part of Intensive Care Medicine, p. 927-934, 2014

• DOI for Long-term outcomes in patients with severe sepsis randomised to resuscitation with hydroxyethyl starch 130/0.42 or Ringer's acetate

Low Serum Super Concentration Predicts 90-Day Survival after Out-Of-Hospital Cardiac Arrest

Jalkanen, V.; Yang, R.; Vaahersalo, J.; Kurola, J. et al.

Part of Intensive Care Medicine, 2014

The predictive value of soluble urokinase plasminogen activator receptor (SuPAR) regarding 90-day mortality and 12-month neurological outcome in critically ill patients after out-of-hospital cardiac arrest. Data from the prospective FINNRESUSCI study

Jalkanen, Ville; Vaahersalo, Jukka; Pettila, Ville; Kurola, Jouni et al.

Part of Resuscitation, p. 1562-1567, 2014

• DOI for The predictive value of soluble urokinase plasminogen activator receptor (SuPAR) regarding 90-day mortality and 12-month neurological outcome in critically ill patients after out-of-hospital cardiac arrest. Data from the prospective FINNRESUSCI study

Moderate Intra-Abdominal Hypertension Leads to Anaerobic Metabolism in the Rectus Abdominis Muscle Tissue of Critically Ill Patients: A Prospective Observational Study

Maddison, Liivi; Karjagin, Juri; Tenhunen, Jyrki; Kirsimaegi, Uelle et al.

Part of BioMed Research International, p. 857492, 2014

• DOI for Moderate Intra-Abdominal Hypertension Leads to Anaerobic Metabolism in the Rectus Abdominis Muscle Tissue of Critically Ill Patients: A Prospective Observational Study
• Download full text (pdf) of Moderate Intra-Abdominal Hypertension Leads to Anaerobic Metabolism in the Rectus Abdominis Muscle Tissue of Critically Ill Patients: A Prospective Observational Study

Validation of Intraluminal and Intraperitoneal microdialysis in ischemic small intestine

Pynnönen, Lauri; Minkkinen, Minna; Perner, Anders; Räty, Sari et al.

Part of BMC Gastroenterology, p. 170, 2013

• DOI for Validation of Intraluminal and Intraperitoneal microdialysis in ischemic small intestine

Association of arterial blood pressure and CPR quality in a child using three different compression techniques, a case report

Sainio, Marko; Sutton, Robert M.; Huhtala, Heini; Eilevstjonn, Joar et al.

Part of Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, p. 51, 2013

• DOI for Association of arterial blood pressure and CPR quality in a child using three different compression techniques, a case report
• Download full text (pdf) of Association of arterial blood pressure and CPR quality in a child using three different compression techniques, a case report

Real-time audiovisual feedback system in a physician-staffed helicopter emergency medical service in Finland: the quality results and barriers to implementation

Sainio, Marko; Kämäräinen, Antti; Huhtala, Heini; Aaltonen, Petri et al.

Part of Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, p. 50, 2013

• DOI for Real-time audiovisual feedback system in a physician-staffed helicopter emergency medical service in Finland: the quality results and barriers to implementation
• Download full text (pdf) of Real-time audiovisual feedback system in a physician-staffed helicopter emergency medical service in Finland: the quality results and barriers to implementation

Factors associated with delayed activation of medical emergency team and excess mortality: An Utstein-style analysis

Tirkkonen, Joonas; Ylä-Mattila, Jari; Olkkola, Klaus T; Huhtala, Heini et al.

Part of Resuscitation, p. 173-178, 2013

• DOI for Factors associated with delayed activation of medical emergency team and excess mortality: An Utstein-style analysis

Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study

Nisula, Sara; Kaukonen, Kirsi-Maija; Vaara, Suvi T; Korhonen, Anna-Maija et al.

Part of Intensive Care Medicine, p. 420-428, 2013

• DOI for Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study

Deeper chest compression - More complications for cardiac arrest patients?

Hellevuo, Heidi; Sainio, Marko; Nevalainen, Riikka; Huhtala, Heini et al.

Part of Resuscitation, p. 760-765, 2013

• DOI for Deeper chest compression - More complications for cardiac arrest patients?

A severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant

Antonen, Jaakko; Leppanen, Ilona; Tenhunen, Jyrki; Arvola, Pertti et al.

Part of Scandinavian Journal of Infectious Diseases, p. 494-496, 2013

• DOI for A severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant

Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units: the FINNRESUSCI study

Vaahersalo, Jukka; Hiltunen, Pamela; Tiainen, Marjaana; Oksanen, Tuomas et al.

Part of Intensive Care Medicine, p. 826-837, 2013

• DOI for Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units: the FINNRESUSCI study

Vital dysfunctions after intensive care discharge: prevalence and impact on patient outcome

Tirkkonen, J.; Olkkola, K. T.; Huhtala, H.; Tenhunen, J. et al.

Part of Acta Anaesthesiologica Scandinavica, p. 56-62, 2013

• DOI for Vital dysfunctions after intensive care discharge: prevalence and impact on patient outcome

Indirect measurement of the vascular endothelial glycocalyx layer thickness in human submucosal capillaries with a plug-in for ImageJ

Liuhanen, Sasu; Sallisalmi, Marko; Pettilä, Ville; Oksala, Niku et al.

Part of Computer Methods and Programs in Biomedicine, p. 38-47, 2013

• DOI for Indirect measurement of the vascular endothelial glycocalyx layer thickness in human submucosal capillaries with a plug-in for ImageJ

SuPAR and PAI-1 in critically ill, mechanically ventilated patients

Jalkanen, Ville; Yang, Runkuan; Linko, Rita; Huhtala, Heini et al.

Part of Intensive Care Medicine, p. 489-496, 2013

• DOI for SuPAR and PAI-1 in critically ill, mechanically ventilated patients

Healthy human CSF promotes glial differentiation of hESC-derived neural cells while retaining spontaneous activity in existing neuronal networks

Kiiski, Heikki; Äänismaa, Riikka; Tenhunen, Jyrki; Hagman, Sanna et al.

Part of Biology open, p. 605-612, 2013

• DOI for Healthy human CSF promotes glial differentiation of hESC-derived neural cells while retaining spontaneous activity in existing neuronal networks
• Download full text (pdf) of Healthy human CSF promotes glial differentiation of hESC-derived neural cells while retaining spontaneous activity in existing neuronal networks

High mobility group B1 impairs hepatocyte regeneration in acetaminophen hepatotoxicity

Yang, Runkuan; Zhang, Shutian; Cotoia, Antonella; Oksala, Niku et al.

Part of BMC Gastroenterology, 2012

• DOI for High mobility group B1 impairs hepatocyte regeneration in acetaminophen hepatotoxicity
• Download full text (pdf) of High mobility group B1 impairs hepatocyte regeneration in acetaminophen hepatotoxicity

Luminal lactate in acute pancreatitis - validation and relation to disease severity

Pynnonen, Lauri; Minkkinen, Minna; Raty, Sari; Sand, Juhani et al.

Part of BMC Gastroenterology, p. 40, 2012

• DOI for Luminal lactate in acute pancreatitis - validation and relation to disease severity

Moderate intra-abdominal hypertension is associated with an increased lactate-pyruvate ratio in the rectus abdominis muscle tissue: a pilot study during laparoscopic surgery

Maddison, Liivi; Karjagin, Juri; Tenhunen, Jyrki; Starkopf, Joel

Part of Annals of Intensive Care, 2012

• DOI for Moderate intra-abdominal hypertension is associated with an increased lactate-pyruvate ratio in the rectus abdominis muscle tissue: a pilot study during laparoscopic surgery

Sympathetic innervation does not contribute to glycerol release in ischemic flaps

Raittinen, Lassi P.; Berg, Leena; Nunes, Silvia; Ahonen, Heikki et al.

Part of Scandinavian Journal of Clinical and Laboratory Investigation, p. 420-426, 2012

• DOI for Sympathetic innervation does not contribute to glycerol release in ischemic flaps

Hydroxyethyl Starch 130/0.4 versus Ringer's Acetate in Severe Sepsis

Perner, Anders; Haase, Nicolai; Guttormsen, Anne B.; Tenhunen, Jyrki et al.

Part of New England Journal of Medicine, p. 124-134, 2012

• DOI for Hydroxyethyl Starch 130/0.4 versus Ringer's Acetate in Severe Sepsis

Drotrecogin Alfa (Activated) in Adults with Septic Shock

Ranieri, V. Marco; Thompson, B. Taylor; Barie, Philip S.; Dhainaut, Jean-Francois et al.

Part of New England Journal of Medicine, p. 2055-2064, 2012

• DOI for Drotrecogin Alfa (Activated) in Adults with Septic Shock

Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose

Yang, Runkuan; Zou, Xiaoping; Koskinen, Marja-Leena; Tenhunen, Jyrki

Part of Critical Care, 2012

• DOI for Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose

Vascular adhesion protein-1 and syndecan-1 in septic shock

Sallisalmi, M; Tenhunen, Jyrki; Yang, R; Oksala, N et al.

Part of Acta Anaesthesiologica Scandinavica, p. 316-322, 2012

• DOI for Vascular adhesion protein-1 and syndecan-1 in septic shock

Evaluation of sublingual microcirculatory blood flow in the critically ill

Sallisalmi, M; Oksala, N; Pettilä, V; Tenhunen, Jyrki

Part of Acta Anaesthesiologica Scandinavica, p. 298-306, 2012

• DOI for Evaluation of sublingual microcirculatory blood flow in the critically ill

Quality controlled manual chest compressions and cerebral oxygenation during in-hospital cardiac arrest

Kämäräinen, Antti; Sainio, Marko; Olkkola, Klaus T; Huhtala, Heini et al.

Part of Resuscitation, p. 138-142, 2012

• DOI for Quality controlled manual chest compressions and cerebral oxygenation during in-hospital cardiac arrest

Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity

Yang, Runkuan; Zhang, Shutian; Kajander, Henri; Zhu, Shengtao et al.

Part of BMC Gastroenterology, p. 125, 2011

• DOI for Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity

Corticosteroid therapy in intensive care unit patients with PCR-confirmed influenza A(H1N1) infection in Finland

Linko, R; Pettilä, V; Ruokonen, E; Varpula, T et al.

Part of Acta Anaesthesiologica Scandinavica, p. 971-979, 2011

• DOI for Corticosteroid therapy in intensive care unit patients with PCR-confirmed influenza A(H1N1) infection in Finland

HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis

Yang, Runkuan; Tenhunen, Jyrki; Tonnessen, Tor Inge

Part of International Journal of Inflammation, 2017

• DOI for HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis
• Download full text (pdf) of HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis

HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure

Yang, Runkuan; Zou, Xiaoping; Tenhunen, Jyrki; Tonnessen, Tor Inge

Part of Mediators of Inflammation, 2017

• DOI for HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure
• Download full text (pdf) of HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure

Usefulness of suPAR as a biological marker in patients with systemic inflammation or infection: a systematic review

Backes, Yara; van der Sluijs, Koenraad F; Mackie, David P; Tacke, Frank et al.

Part of Intensive Care Medicine, p. 1418-1428, 2012

• DOI for Usefulness of suPAR as a biological marker in patients with systemic inflammation or infection: a systematic review
• Download full text (pdf) of Usefulness of suPAR as a biological marker in patients with systemic inflammation or infection: a systematic review