Liqun He
Researcher at Department of Immunology, Genetics and Pathology; Research programme: Vascular Biology; Research group Christer Betsholtz
- E-mail:
- liqun.he@igp.uu.se
- Visiting address:
- Dag Hammarskjölds väg 20
751 85 Uppsala - Postal address:
- Rudbecklaboratoriet
751 85 UPPSALA
Publications
Recent publications
-
Loss of angiopoietin-2 leads to region-specific brain malformations and blood-brain barrier leakage
Part of JCI Insight, 2026
- DOI for Loss of angiopoietin-2 leads to region-specific brain malformations and blood-brain barrier leakage
- Download full text (pdf) of Loss of angiopoietin-2 leads to region-specific brain malformations and blood-brain barrier leakage
-
Part of Microvascular Research, 2026
- DOI for Distinct gene expression profiles in blood-brain barrier capillary endothelial cells between mice and humans
- Download full text (pdf) of Distinct gene expression profiles in blood-brain barrier capillary endothelial cells between mice and humans
-
Part of Molecular Oncology, 2025
- DOI for Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
- Download full text (pdf) of Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
-
A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
Part of EMBO Reports, p. 5326-5359, 2025
- DOI for A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
- Download full text (pdf) of A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
-
Part of Journal of Clinical Investigation, 2025
All publications
Articles in journal
-
Loss of angiopoietin-2 leads to region-specific brain malformations and blood-brain barrier leakage
Part of JCI Insight, 2026
- DOI for Loss of angiopoietin-2 leads to region-specific brain malformations and blood-brain barrier leakage
- Download full text (pdf) of Loss of angiopoietin-2 leads to region-specific brain malformations and blood-brain barrier leakage
-
Part of Microvascular Research, 2026
- DOI for Distinct gene expression profiles in blood-brain barrier capillary endothelial cells between mice and humans
- Download full text (pdf) of Distinct gene expression profiles in blood-brain barrier capillary endothelial cells between mice and humans
-
Part of Molecular Oncology, 2025
- DOI for Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
- Download full text (pdf) of Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
-
A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
Part of EMBO Reports, p. 5326-5359, 2025
- DOI for A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
- Download full text (pdf) of A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
-
Part of Journal of Clinical Investigation, 2025
-
Distinguishing subtypes of endothelial cells in the mouse aorta
Part of Proceedings of the National Academy of Sciences of the United States of America, 2025
- DOI for Distinguishing subtypes of endothelial cells in the mouse aorta
- Download full text (pdf) of Distinguishing subtypes of endothelial cells in the mouse aorta
-
Part of Journal of Clinical Investigation, 2025
- DOI for TIE2 activation by antibody-clustered endogenous angiopoietin-2 prevents capillary loss and fibrosis in experimental kidney disease
- Download full text (pdf) of TIE2 activation by antibody-clustered endogenous angiopoietin-2 prevents capillary loss and fibrosis in experimental kidney disease
-
Part of eLIFE, 2025
- DOI for Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis
- Download full text (pdf) of Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis
-
Part of JCI Insight, 2024
- DOI for Distinct strategies for intravascular triglyceride metabolism in hearts of mammals and lower vertebrate species
- Download full text (pdf) of Distinct strategies for intravascular triglyceride metabolism in hearts of mammals and lower vertebrate species
-
Part of Vascular pharmacology, 2024
- DOI for Different gene expression patterns between mouse and human brain pericytes revealed by single-cell/nucleus RNA sequencing
- Download full text (pdf) of Different gene expression patterns between mouse and human brain pericytes revealed by single-cell/nucleus RNA sequencing
-
Single-cell dissection of the human blood-brain barrier and glioma blood-tumor barrier
Part of Neuron, 2024
-
Part of Nature Communications, 2024
- DOI for Adipose stem cells are sexually dimorphic cells with dual roles as preadipocytes and resident fibroblasts
- Download full text (pdf) of Adipose stem cells are sexually dimorphic cells with dual roles as preadipocytes and resident fibroblasts
-
A brain-specific angiogenic mechanism enabled by tip cell specialization
Part of Nature, p. 863-871, 2024
- DOI for A brain-specific angiogenic mechanism enabled by tip cell specialization
- Download full text (pdf) of A brain-specific angiogenic mechanism enabled by tip cell specialization
-
Part of International Journal of Molecular Sciences, 2024
- DOI for Renal Endothelial Single-Cell Transcriptomics Reveals Spatiotemporal Regulation and Divergent Roles of Differential Gene Transcription and Alternative Splicing in Murine Diabetic Nephropathy
- Download full text (pdf) of Renal Endothelial Single-Cell Transcriptomics Reveals Spatiotemporal Regulation and Divergent Roles of Differential Gene Transcription and Alternative Splicing in Murine Diabetic Nephropathy
-
The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier
Part of European Journal of Cell Biology, 2024
- DOI for The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier
- Download full text (pdf) of The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier
-
The role of dendrin in IgA nephropathy
Part of Nephrology, Dialysis and Transplantation, p. 311-321, 2023
- DOI for The role of dendrin in IgA nephropathy
- Download full text (pdf) of The role of dendrin in IgA nephropathy
-
Molecular anatomy of adult mouse leptomeninges
Part of Neuron, 2023
- DOI for Molecular anatomy of adult mouse leptomeninges
- Download full text (pdf) of Molecular anatomy of adult mouse leptomeninges
-
Wnt signaling regulates MFSD2A-dependent drug delivery through endothelial transcytosis in glioma
Part of Neuro-Oncology, p. 1073-1084, 2023
-
Part of Kidney International, p. 752-765, 2022
-
Part of BIOLOGY OPEN, 2022
- DOI for Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFR alpha signalling in cerebellar development
- Download full text (pdf) of Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFR alpha signalling in cerebellar development
-
A single-cell transcriptomic inventory of murine smooth muscle cells
Part of Developmental Cell, p. 2426-+, 2022
- DOI for A single-cell transcriptomic inventory of murine smooth muscle cells
- Download full text (pdf) of A single-cell transcriptomic inventory of murine smooth muscle cells
-
Part of Stem Cell Reports, p. 1089-1104, 2022
-
ECO: An Integrated Gene Expression Omnibus for Mouse Endothelial Cells In Vivo
Part of Frontiers in Genetics, 2022
- DOI for ECO: An Integrated Gene Expression Omnibus for Mouse Endothelial Cells In Vivo
- Download full text (pdf) of ECO: An Integrated Gene Expression Omnibus for Mouse Endothelial Cells In Vivo
-
Endothelium-derived lactate is required for pericyte function and blood-brain barrier maintenance
Part of EMBO Journal, 2022
-
Part of Nature Communications, 2022
- DOI for ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels
- Download full text (pdf) of ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels
-
Specification of CNS macrophage subsets occurs postnatally in defined niches
Part of Nature, p. 740-+, 2022
-
Part of Developmental Cell, p. 1383-13990000000, 2022
-
Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss
Part of Circulation Research, 2021
-
Part of Journal of Experimental & Clinical Cancer Research, 2021
- DOI for Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis
- Download full text (pdf) of Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis
-
VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration
Part of Circulation, p. 65-77, 2021
- DOI for VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration
- Download full text (pdf) of VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration
-
Part of Circulation, p. 865-868, 2021
-
Role of Venous Endothelial Cells in Developmental and Pathologic Angiogenesis
Part of Circulation, p. 1308-1322, 2021
-
Part of Frontiers in Oncology, 2021
- DOI for Uncovering a Distinct Gene Signature in Endothelial Cells Associated With Contrast Enhancement in Glioblastoma
- Download full text (pdf) of Uncovering a Distinct Gene Signature in Endothelial Cells Associated With Contrast Enhancement in Glioblastoma
-
Part of Cellular Oncology, p. 193-204, 2021
-
Transcription factor FOXP2 is a flow-induced regulator of collecting lymphatic vessels
Part of EMBO Journal, 2021
- DOI for Transcription factor FOXP2 is a flow-induced regulator of collecting lymphatic vessels
- Download full text (pdf) of Transcription factor FOXP2 is a flow-induced regulator of collecting lymphatic vessels
-
Part of Neuro-Oncology, p. 398-411, 2021
- DOI for ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
- Download full text (pdf) of ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
-
Part of Neuro-Oncology, p. 2095-2106, 2021
- DOI for Blood-brain barrier alterations in human brain tumors revealed by genome-wide transcriptomic profiling
- Download full text (pdf) of Blood-brain barrier alterations in human brain tumors revealed by genome-wide transcriptomic profiling
-
A human cell type similar to murine central nervous system perivascular fibroblasts
Part of Experimental Cell Research, 2021
- DOI for A human cell type similar to murine central nervous system perivascular fibroblasts
- Download full text (pdf) of A human cell type similar to murine central nervous system perivascular fibroblasts
-
Part of JCI Insight, 2021
- DOI for Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing
- Download full text (pdf) of Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing
-
Part of Frontiers in Genetics, 2021
- DOI for An Integrated Transcriptome Analysis Reveals IGFBP7 Upregulation in Vasculature in Traumatic Brain Injury
- Download full text (pdf) of An Integrated Transcriptome Analysis Reveals IGFBP7 Upregulation in Vasculature in Traumatic Brain Injury
-
Part of Journal of Molecular Medicine, p. 859-876, 2021
-
Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain
Part of Cell Reports, 2020
- DOI for Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain
- Download full text (pdf) of Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain
-
Part of Nature Communications, 2020
- DOI for Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
- Download full text (pdf) of Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
-
Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis
Part of International Journal of Cancer, p. 2634-2644, 2020
- DOI for Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis
- Download full text (pdf) of Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis
-
Part of Clinical Epigenetics, 2020
- DOI for Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression
- Download full text (pdf) of Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression
-
Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung
Part of American Journal of Physiology - Lung cellular and Molecular Physiology, 2020
-
Part of eLIFE, 2020
- DOI for Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
- Download full text (pdf) of Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
-
GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients
Part of eLIFE, 2019
- DOI for GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients
- Download full text (pdf) of GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients
-
Part of Genome Medicine, 2018
-
Part of Scientific Reports, 2018
- DOI for Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier
- Download full text (pdf) of Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier
-
Part of Cell Metabolism, p. 713-726, 2017
-
Part of BMC Cancer, 2017
- DOI for Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition
- Download full text (pdf) of Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition
-
Part of Oncotarget, p. 98646-98659, 2017
-
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema
Part of Scientific Reports, 2017
- DOI for Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema
- Download full text (pdf) of Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema
-
Pericytes promote the generation of oligodendrocytes during remyelination
Part of Glia, 2017
-
Analysis of the brain mural cell transcriptome
Part of Scientific Reports, 2016
- DOI for Analysis of the brain mural cell transcriptome
- Download full text (pdf) of Analysis of the brain mural cell transcriptome
-
Part of Science Signaling, 2016
-
Part of BIOLOGY OPEN, p. 461-474, 2016
- DOI for A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex
- Download full text (pdf) of A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex
-
Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia
Part of Clinical Cancer Research, p. 6217-6227, 2016
-
Part of Clinical Cancer Research, p. 2417-2426, 2016
-
Notch3 Is Necessary for Blood Vessel Integrity in the Central Nervous System
Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 409-420, 2015
-
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
Part of Science, p. 1138-1142, 2015
-
Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium
Part of PLOS ONE, 2015
-
Part of PLOS ONE, 2014
- DOI for Characterization of Platelet-Derived Growth Factor-A Expression in Mouse Tissues Using a lacZ Knock-In Approach
- Download full text (pdf) of Characterization of Platelet-Derived Growth Factor-A Expression in Mouse Tissues Using a lacZ Knock-In Approach
-
Part of PLOS ONE, 2013
- DOI for Wtip- and Gadd45a-Interacting Protein Dendrin Is Not Crucial for the Development or Maintenance of the Glomerular Filtration Barrier
- Download full text (pdf) of Wtip- and Gadd45a-Interacting Protein Dendrin Is Not Crucial for the Development or Maintenance of the Glomerular Filtration Barrier