Chenyan Zhao

Semi-mechanistic pharmacokinetic-pharmacodynamic modelling of antibiotic drug combinations

Brill, Margreke J. E.; Kristoffersson, Anders; Zhao, Chenyan; Nielsen, Elisabet I. et al.

Part of Clinical Microbiology and Infection, p. 697-706, 2018

• DOI for Semi-mechanistic pharmacokinetic-pharmacodynamic modelling of antibiotic drug combinations

An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae

Zhao, Chenyan; van den Berg, Sanne; Wang, Zhigang; Olsson, Anna et al.

Part of International Journal of Antimicrobial Agents, 2025

• DOI for An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae
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Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Zhao, Chenyan; Kristoffersson, Anders N.; Khan, David D.; Lagerbäck, Pernilla et al.

Part of Scientific Reports, 2024

• DOI for Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model
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Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time-kill experiments: high agreement with in silico predictions

Olsson, Anna; Malmberg, Christer; Zhao, Chenyan; Friberg, Lena et al.

Part of Journal of Antimicrobial Chemotherapy, 2023

• DOI for Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time-kill experiments: high agreement with in silico predictions
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Quantifying effects of antimicrobial drug combinations by modelling and simulation

Zhao, Chenyan

2023

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Population pharmacokinetics of apramycin from first-in-human plasma and urine data to support prediction of efficacious dose

Zhao, Chenyan; Chirkova, Anna; Rosenborg, Staffan; Palma Villar, Rodrigo et al.

Part of Journal of Antimicrobial Chemotherapy, p. 2718-2728, 2022

• DOI for Population pharmacokinetics of apramycin from first-in-human plasma and urine data to support prediction of efficacious dose
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An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae

Zhao, Chenyan; van den Berg, Sanne; Wang, Zhigang; Olsson, Anna et al.

Part of International Journal of Antimicrobial Agents, 2025

• DOI for An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae
• Download full text (pdf) of An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae

Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Zhao, Chenyan; Kristoffersson, Anders N.; Khan, David D.; Lagerbäck, Pernilla et al.

Part of Scientific Reports, 2024

• DOI for Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model
• Download full text (pdf) of Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time-kill experiments: high agreement with in silico predictions

Olsson, Anna; Malmberg, Christer; Zhao, Chenyan; Friberg, Lena et al.

Part of Journal of Antimicrobial Chemotherapy, 2023

• DOI for Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time-kill experiments: high agreement with in silico predictions
• Download full text (pdf) of Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time-kill experiments: high agreement with in silico predictions

Population pharmacokinetics of apramycin from first-in-human plasma and urine data to support prediction of efficacious dose

Zhao, Chenyan; Chirkova, Anna; Rosenborg, Staffan; Palma Villar, Rodrigo et al.

Part of Journal of Antimicrobial Chemotherapy, p. 2718-2728, 2022

• DOI for Population pharmacokinetics of apramycin from first-in-human plasma and urine data to support prediction of efficacious dose
• Download full text (pdf) of Population pharmacokinetics of apramycin from first-in-human plasma and urine data to support prediction of efficacious dose

Combination of polymyxin B and minocycline against multidrug-resistant Klebsiella pneumoniae: interaction quantified by pharmacokinetic/pharmacodynamic modelling from in vitro data

Zhao, Chenyan; Wistrand-Yuen, Pikkei; Lagerbäck, Pernilla; Tängdén, Thomas et al.

Part of International Journal of Antimicrobial Agents, 2020

• DOI for Combination of polymyxin B and minocycline against multidrug-resistant Klebsiella pneumoniae: interaction quantified by pharmacokinetic/pharmacodynamic modelling from in vitro data
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Semi-mechanistic pharmacokinetic-pharmacodynamic modelling of antibiotic drug combinations

Brill, Margreke J. E.; Kristoffersson, Anders; Zhao, Chenyan; Nielsen, Elisabet I. et al.

Part of Clinical Microbiology and Infection, p. 697-706, 2018

• DOI for Semi-mechanistic pharmacokinetic-pharmacodynamic modelling of antibiotic drug combinations

Quantifying effects of antimicrobial drug combinations by modelling and simulation

Zhao, Chenyan

2023

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Translational PKPD modelling and simulation framework to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae

Zhao, Chenyan; van den Berg, Sanne; Wang, Zhigang; Olsson, Anna et al.

A framework to assess antibiotic effects using time-lapse microscopy

Wehrhahn, Eva; Zhao, Chenyan; Wistrand-Yuen, Pikkei; Brill, Margreke et al.