Jaafar Khaled

Characterization of hepatocellular carcinoma patient-derived organoids from patients receiving transarterial chemoembolization as a model for preclinical drug response assessment

Khaled, Jaafar; Sennefelt Nyman, Sofi; Dahlgren, David; Rorsman, Fredrik et al.

Part of Scientific Reports, 2026

• DOI for Characterization of hepatocellular carcinoma patient-derived organoids from patients receiving transarterial chemoembolization as a model for preclinical drug response assessment
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Inhibition of PERK signaling suppresses tumor progression and blocks GP73-GRP78-dependent stromal activation in hepatocellular carcinoma

Khaled, Jaafar; Kopsida, Maria; Serafín, Tania Payo; Sennefelt Nyman, Sofi et al.

Part of Neoplasia, p. 101329-101329, 2026

• DOI for Inhibition of PERK signaling suppresses tumor progression and blocks GP73-GRP78-dependent stromal activation in hepatocellular carcinoma

Endoplasmic reticulum stress signaling as a therapeutic target: Mechanisms and treatment response in hepatocellular carcinoma

Khaled, Jaafar

2026

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Gastrointestinal side effects in hepatocellular carcinoma patients receiving transarterial chemoembolization: a meta-analysis of 81 studies and 9495 patients

Arendt, Nathalie; Kopsida, Maria; Khaled, Jaafar; Sjöblom, Markus et al.

Part of Therapeutic Advances in Medical Oncology, p. 1-30, 2025

• DOI for Gastrointestinal side effects in hepatocellular carcinoma patients receiving transarterial chemoembolization: a meta-analysis of 81 studies and 9495 patients
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Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells

Kopsida, Maria; Clavero, Ada Lerma; Khaled, Jaafar; Balgoma, David et al.

Part of Molecular Metabolism, 2024

• DOI for Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells
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Characterization of hepatocellular carcinoma patient-derived organoids from patients receiving transarterial chemoembolization as a model for preclinical drug response assessment

Khaled, Jaafar; Sennefelt Nyman, Sofi; Dahlgren, David; Rorsman, Fredrik et al.

Part of Scientific Reports, 2026

• DOI for Characterization of hepatocellular carcinoma patient-derived organoids from patients receiving transarterial chemoembolization as a model for preclinical drug response assessment
• Download full text (pdf) of Characterization of hepatocellular carcinoma patient-derived organoids from patients receiving transarterial chemoembolization as a model for preclinical drug response assessment

Inhibition of PERK signaling suppresses tumor progression and blocks GP73-GRP78-dependent stromal activation in hepatocellular carcinoma

Khaled, Jaafar; Kopsida, Maria; Serafín, Tania Payo; Sennefelt Nyman, Sofi et al.

Part of Neoplasia, p. 101329-101329, 2026

• DOI for Inhibition of PERK signaling suppresses tumor progression and blocks GP73-GRP78-dependent stromal activation in hepatocellular carcinoma

Gastrointestinal side effects in hepatocellular carcinoma patients receiving transarterial chemoembolization: a meta-analysis of 81 studies and 9495 patients

Arendt, Nathalie; Kopsida, Maria; Khaled, Jaafar; Sjöblom, Markus et al.

Part of Therapeutic Advances in Medical Oncology, p. 1-30, 2025

• DOI for Gastrointestinal side effects in hepatocellular carcinoma patients receiving transarterial chemoembolization: a meta-analysis of 81 studies and 9495 patients
• Download full text (pdf) of Gastrointestinal side effects in hepatocellular carcinoma patients receiving transarterial chemoembolization: a meta-analysis of 81 studies and 9495 patients

Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells

Kopsida, Maria; Clavero, Ada Lerma; Khaled, Jaafar; Balgoma, David et al.

Part of Molecular Metabolism, 2024

• DOI for Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells
• Download full text (pdf) of Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells

Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma

Calitz, Carlemi; Rosenquist, Jenny; Degerstedt, Oliver; Khaled, Jaafar et al.

Part of Scientific Reports, 2023

• DOI for Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma
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Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival

Sennefelt Nyman, Sofi; Ahlström, Håkan; Dimopoulou, Angeliki; Dahlgren, David et al.

Part of BMJ Open, 2022

• DOI for Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival
• Download full text (pdf) of Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival

Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma

Khaled, Jaafar; Kopsida, Maria; Lennernäs, Hans; Heindryckx, Femke

Part of Cells, 2022

• DOI for Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma
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Endoplasmic reticulum stress signaling as a therapeutic target: Mechanisms and treatment response in hepatocellular carcinoma

Khaled, Jaafar

2026

• Download full text (pdf) of Endoplasmic reticulum stress signaling as a therapeutic target: Mechanisms and treatment response in hepatocellular carcinoma

Pharmacological inhibition of PERK during early carcinogenesis restrains tumor progression and remodels the tumor microenvironment in hepatocellular carcinoma

Khaled, Jaafar; Kopsida, Maria; Payo Serafín, Tania; Sennefelt Nyman, Sofi et al.

Treatment with tauroursodeoxycholic acid reduces tumor burden during early hepatocarcinogenesis in a mouse model for HCC

Khaled, Jaafar; Kopsida, Maria; Heindryckx, Femke

Characterization of hepatocellular carcinoma patient-derived organoids receiving transarterial chemoembolization as a preclinical model for drug response assessment

Khaled, Jaafar; Sennefelt Nyman, Sofi; Rorsman, Fredrik; Lennernäs, Hans et al.

Pharmacokinetics and safety profile of idarubicin-lipiodol chemoembolization of hepatocellular carcinoma

Dahlgren, David; Sennefelt Nyman, Sofi; Niessen, Janis; Dimopoulou, Angeliki et al.