Ulf Landegren

A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification

Ikebuchi, Ryoyo; Lu, Xi; Bouri, Dimitra; Svintytska, Valeriia et al.

Part of PLOS ONE, 2025

DOI for A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification
Download full text (pdf) of A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification

Nanoplasmonic Rapid Antimicrobial-Resistance Point-of-Care Identification Device: RAPIDx

Lee, Jong-Hwan; Song, Jihwan; Hong, SoonGweon; Kim, Yun et al.

Part of Advanced Healthcare Materials, 2025

DOI for Nanoplasmonic Rapid Antimicrobial-Resistance Point-of-Care Identification Device: RAPIDx

Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA)

Wang, Mengqi; Kamali-Moghaddam, Masood; Löf, Liza; Fernandez, Matilde Cortabarria et al.

Part of Scientific Reports, 2024

Sensitive and Specific Analyses of Colorectal Cancer Recurrence through Multiplex superRCA Mutation Detection in Blood Plasma

Sandberg, Emma; Nunes, Luís; Edqvist, Per-Henrik; Mathot, Lucy et al.

Part of Cancers, 2024

Managing leukemia patients via liquid biopsy and super rolling circle amplification (superRCA)

Robelius, Anna; Chen, Lei; Amini, Rose-Marie; Cavelier, Lucia et al.

Part of Journal of Internal Medicine, p. 228-237, 2023

DOI for Managing leukemia patients via liquid biopsy and super rolling circle amplification (superRCA)

Ultra-sensitive monitoring of leukemia patients using superRCA mutation detection assays

Chen, Lei; Eriksson, Anna; Weström, Simone; Pandzic, Tatjana et al.

Part of Nature Communications, 2022

Detection of SARS-CoV-2 antibodies in serum and dried blood spot samples of vaccinated individuals using a sensitive homogeneous proximity extension assay

Zhao, Hongxing; Wang, Mengqi; Muthelo, Phathutshedzo; Löf, Liza et al.

Part of New Biotechnology, p. 139-148, 2022

Surface protein profiling of prostate-derived extracellular vesicles by mass spectrometry and proximity assays

Doulabi, Ehsan Manouchehri; Fredolini, Claudia; Gallini, Radiosa; Löf, Liza et al.

Part of Communications Biology, 2022

Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ

Al-Amin, Rasel A.; Johansson, Lars; Abdurakhmanov, Eldar; Landegren, Nils et al.

Part of Nucleic Acids Research, 2022

Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents

Al-Amin, Rasel Abdullah; Muthelo, Phathutshedzo M.; Abdurakhmanov, Eldar; Vincke, Cecile et al.

Part of Analytical Chemistry, p. 10054-10061, 2022

Image-based high-throughput mapping of TGF-beta-induced phosphocomplexes at a single-cell level

Lönn, Peter; Al-Amin, Abdullah; Doulabi, Ehsan Manouchehri; Heldin, Johan et al.

Part of Communications Biology, 2021

Sensitive Measurement of Drug-Target Engagement by a Cellular Thermal Shift Assay with Multiplex Proximity Extension Readout

Al-Amin, Rasel A.; Gallant, Caroline J.; Muthelo, Phathutshedzo M.; Landegren, Ulf

Part of Analytical Chemistry, p. 10999-11009, 2021

Human proteins incorporated into tick-borne encephalitis virus revealed by in situ proximity ligation

Ikebuchi, Ryoyo; Isaac, Alfred W.; Yoshii, Kentaro; Doulabi, Ehsan Manouchehri et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 714-719, 2020

A multiplex platform for digital measurement of circular DNA reaction products

Björkesten, Johan; Patil, Sourabh; Fredolini, Claudia; Lönn, Peter et al.

Part of Nucleic Acids Research, 2020

DOI for A multiplex platform for digital measurement of circular DNA reaction products

Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues

Lindskog, Cecilia; Backman, Max; Zieba, Agata; Asplund, Anna et al.

Part of Journal of Histochemistry and Cytochemistry, p. 515-529, 2020

DOI for Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues

A compendium on single-cell analysis for the curious

Gallant, Caroline J.; Landegren, Ulf

Part of The FEBS Journal, p. 1442-1444, 2019

DOI for A compendium on single-cell analysis for the curious

Profiling surface proteins on individual exosomes using a proximity barcoding assay

Wu, Di; Yan, Junhong; Shen, Xia; Sun, Yu et al.

Part of Nature Communications, 2019

Protein profiling of fine-needle aspirates reveals subtype-associated immune signatures and involvement of chemokines in breast cancer

Franzen, Bo; Alexeyenko, Andrey; Kamali-Moghaddam, Masood; Hatschek, Thomas et al.

Part of Molecular Oncology, p. 376-391, 2019

Next wave advances in single-cell analyses

Herr, Amy E.; Kitamori, Takehiko; Landegren, Ulf; Kamali-Moghaddam, Masood

Part of The Analyst, p. 735-737, 2019

DOI for Next wave advances in single-cell analyses

Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes

Klaesson, Axel; Grannas, Karin; Ebai, Tonge; Heldin, Johan et al.

Part of Scientific Reports, 2018

Protein Profiling in Serum and Cerebrospinal Fluid Following Complex Surgery on the Thoracic Aorta Identifies Biological Markers of Neurologic Injury.

Lindblom, Rickard P F; Shen, Qiujin; Axén, Sofie; Landegren, Ulf et al.

Part of Journal of Cardiovascular Translational Research, p. 503-516, 2018

DOI for Protein Profiling in Serum and Cerebrospinal Fluid Following Complex Surgery on the Thoracic Aorta Identifies Biological Markers of Neurologic Injury.

Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays

Shen, Qiujin; Björkesten, Johan; Galli, Joakim; Ekman, Daniel et al.

Part of Clinical Chemistry and Laboratory Medicine, p. 582-594, 2018

DOI for Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays

A fine-needle aspiration-based protein signature discriminates benign from malignant breast lesions

Franzen, Bo; Kamali-Moghaddam, Masood; Alexeyenko, Andrey; Hatschek, Thomas et al.

Part of Molecular Oncology, p. 1415-1428, 2018

In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation

Zieba, Agata; Ponten, Fredrik; Uhlen, Mathias; Landegren, Ulf

Part of Modern Pathology, p. 253-263, 2018

DOI for In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors

Schuette, Moritz; Risch, Thomas; Abdavi-Azar, Nilofar; Boehnke, Karsten et al.

Part of Nature Communications, 2017

Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation

Padhan, Narendra; Yan, Junhong; Boge, Annegret; Scrivener, Elaine et al.

Part of Scientific Reports, 2017

Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia

Löf, Liza; Arngården, Linda; Olsson-Strömberg, Ulla; Siart, Benjamin et al.

Part of Scientific Reports, p. 1-9, 2017

Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.

Larssen, Pia; Wik, Lotta; Czarnewski, Paulo; Eldh, Maria et al.

Part of Molecular & Cellular Proteomics, 2017

DOI for Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.

Stability of Proteins in Dried Blood Spot Biobanks.

Björkesten, Johan; Enroth, Stefan; Shen, Qiujin; Wik, Lotta et al.

Part of Molecular & Cellular Proteomics, p. 1286-1296, 2017

Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay

Larssen, Pia; Wik, Lotta; Czarnewski, Paulo; Eldh, Maria et al.

Part of Molecular & Cellular Proteomics, p. 502-511, 2017

DOI for Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay

Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification

Ebai, Tonge; de Oliveira, Felipe Marques Souza; Löf, Liza; Wik, Lotta et al.

Part of Clinical Chemistry, p. 1497-1505, 2017

DOI for Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Darmanis, Spyros; Gallant, Caroline Julie; Marinescu, Voichita Dana; Niklasson, Mia et al.

Part of Cell Reports, p. 380-389, 2016

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction

Genshaft, Alex S.; Li, Shuqiang; Gallant, Caroline J.; Darmanis, Spyros et al.

Part of Genome Biology, 2016

Detecting individual extracellular vesicles using a multicolor in situ proximity ligation assay with flow cytometric readout

Löf, Liza; Ebai, Tonge; Dubois, Louise; Wik, Lotta et al.

Part of Scientific Reports, 2016

Single Chain Antibodies as Tools to Study transforming growth factor--Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens

Blokzijl, Andries; Zieba, Agata; Hust, Michael; Schirrmann, Thomas et al.

Part of Molecular & Cellular Proteomics, p. 1848-1856, 2016

DOI for Single Chain Antibodies as Tools to Study transforming growth factor--Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens

Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay

Blokzijl, Andries; Chen, Lei; Gustafsdottir, Sigrun M.; Vuu, Jimmy et al.

Part of PLOS ONE, 2016

Detection of prognostic biomarkers with solid-phase proximity ligation assay in patients with colorectal cancer

Ghanipour, Lana; Darmanis, Spyros; Landegren, Ulf; Glimelius, Bengt et al.

Part of Translational Oncology, p. 251-255, 2016

A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients

Lind, Anne-Li; Yu, Di; Freyhult, Eva; Bodolea, Constantin et al.

Part of PLOS ONE, 2016

AFFINOMICS and the prospects for large-scale protein analyses

Landegren, Ulf

Part of New Biotechnology, p. 491-493, 2016

DOI for AFFINOMICS and the prospects for large-scale protein analyses

Pla Flow; A Flow Cytometry-Based Assay For Detection Of Bcr-Abl Fusion Protein In Blood Cells From Cml Patients

Löf, Liza; Olsson-Strömberg, Ulla; Landegren, Ulf; Kamali-Moghaddam, Masood

Part of Haematologica, p. 457-458, 2016

Clinical Relevance Of Recurrent Allele-Specific Recombination Expressing The Wnt10Bivs1 Allele Variant In Acute Myeloid Leukemia

Beghini, A.; Lazzaroni, F.; Del Giacco, L.; Söderberg, Ola et al.

Part of Haematologica, p. 668-669, 2016

Visualization of Borna Disease Virus Protein Interactions with Host Proteins using in situ Proximity Ligation Assay

Johansson Wensman, Jonas; Leuchowius, Karl-Johan; Yan, Jiting; Berg, Anna-Lena et al.

Part of British journal of virology, p. 11-23, 2016

DOI for Visualization of Borna Disease Virus Protein Interactions with Host Proteins using in situ Proximity Ligation Assay

Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome

Gu, Gucci Jijuan; Friedman, Mikaela; Ren, Ping; Torn, Carina et al.

Part of Scientific Reports, 2015

BBMRI-ERIC as a resource for pharmaceutical and life science industries: the development of biobank-based Expert Centres

van Ommen, Gert-Jan B; Törnwall, Outi; Bréchot, Christian; Dagher, Georges et al.

Part of European Journal of Human Genetics, p. 893-900, 2015

DOI for BBMRI-ERIC as a resource for pharmaceutical and life science industries: the development of biobank-based Expert Centres

The Biobanking Analysis Resource Catalogue (BARCdb): a new research tool for the analysis of biobank samples.

Galli, Joakim; Oelrich, Johan; Taussig, Michael J; Andreasson, Ulrika et al.

Part of Nucleic Acids Research, 2015

DOI for The Biobanking Analysis Resource Catalogue (BARCdb): a new research tool for the analysis of biobank samples.

CK1 delta restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1 alpha/ARNT complex formation

Kourti, Maria; Ikonomou, Georgia; Giakoumakis, Nikolaos-Nikiforos; Rapsomaniki, Maria Anna et al.

Part of Cellular Signalling, p. 1129-1140, 2015

FLOW CYTOMETRY-BASED ASSAY FOR DETECTION OF BCR-ABL FUSION PROTEIN IN BLOOD CELLS FROM CML PATIENTS

Löf, Liza; Olsson-Strömberg, Ulla; Landegren, Ulf; Kamali-Moghaddam, Masood

Part of Haematologica, p. 694-695, 2015

Parallel protein detection by solid-phase proximity ligation assay with real-time PCR or sequencing

Ebai, Tonge; Kamali-Moghaddam, Masood; Landegren, Ulf

Part of Current Protocol in Molecular Biology, 2015

DOI for Parallel protein detection by solid-phase proximity ligation assay with real-time PCR or sequencing

Öppenheten förstör chansen till patent

Arvidsson, Per I.; Domeij, Bengt; Hansson, Mats G.; Landegren, Ulf et al.

Part of Svenska dagbladet, 2015

Sensitivity and Specificity of In situ Proximity Ligation for Protein Interaction Analysis in a Model of Steatohepatitis with Mallory-Denk Bodies

Zatloukal, Bernhard; Kufferath, Iris; Thueringer, Andrea; Landegren, Ulf et al.

Part of PLOS ONE, 2014

A Universal Approach to Prepare Reagents for DNA-Assisted Protein Analysis

Yan, Junhong; Gu, Gucci Jijuan; Jost, Christian; Hammond, Maria et al.

Part of PLOS ONE, 2014

Sensitive detection of aggregated prion protein via proximity ligation

Hammond, Maria; Wik, Lotta; Deslys, Jean-Philippe; Comoy, Emmanuel et al.

Part of Prion, p. 261-265, 2014

DOI for Sensitive detection of aggregated prion protein via proximity ligation

Role of Individual MARK Isoforms in Phosphorylation of Tau at Ser²⁶² in Alzheimer's Disease

Gu, Gucci Jijuan; Lund, Harald; Wu, Di; Blokzijl, Andries et al.

Part of Neuromolecular medicine, p. 458-469, 2013

DOI for Role of Individual MARK Isoforms in Phosphorylation of Tau at Ser²⁶² in Alzheimer's Disease

Parallel Visualization of Multiple Protein Complexes in Individual Cells in Tumor Tissue

Leuchowius, Karl-Johan; Clausson, Carl-Magnus; Grannas, Karin; Erbilgin, Yücel et al.

Part of Molecular & Cellular Proteomics, p. 1563-1571, 2013

DOI for Parallel Visualization of Multiple Protein Complexes in Individual Cells in Tumor Tissue

Improving Precision of Proximity Ligation Assay by Amplified Single Molecule Detection

Ke, Rongqin; Nong, Rachel Yuan; Fredriksson, Simon; Landegren, Ulf et al.

Part of PLOS ONE, 2013

Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation

Gu, Gucci Jijuan; Friedman, Mikaela; Jost, Christian; Johnsson, Kai et al.

Part of New Biotechnology, p. 144-152, 2013

DOI for Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation

Elevated MARK2-Dependent Phosphorylation of Tau in Alzheimer's Disease

Gu, Gucci Jijuan; Wu, Di; Lund, Harald; Sunnemark, Dan et al.

Part of Journal of Alzheimer's Disease, p. 699-713, 2013

DOI for Elevated MARK2-Dependent Phosphorylation of Tau in Alzheimer's Disease

Workshop on laboratory protocol standards for the molecular methods database

Klingström, Tomas; Soldatova, Larissa; Stevens, Robert; Roos, Erik et al.

Part of New Biotechnology, p. 109-113, 2013

DOI for Workshop on laboratory protocol standards for the molecular methods database

Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion

Sundqvist, Anders; Zieba, Agata; Vasilaki, Eleftheria; Herrera Hidalgo, Carmen et al.

Part of Oncogene, p. 3606-3615, 2013

DOI for Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion

Solid-phase proximity ligation assays for individual or parallel protein analyses with readout via real-time PCR or sequencing

Nong, Rachel Yuan; Wu, Di; Yan, Junhong; Hammond, Maria et al.

Part of Nature Protocols, p. 1234-1248, 2013

Multiplex protein detection with DNA readout via mass spectrometry

Flanigon, James; Kamali-Moghaddam, Masood; Burbulis, Ian; Annink, Carla et al.

Part of New Biotechnology, p. 153-158, 2013

DOI for Multiplex protein detection with DNA readout via mass spectrometry

Offshoots of the ESF functional genomics programme

Landegren, Ulf

Part of New Biotechnology, p. 296-298, 2013

DOI for Offshoots of the ESF functional genomics programme

Improving the Diagnosis and Management of Neuroendocrine Tumors: Utilizing New Advances in Biomarker and Molecular Imaging Science

Giandomenico, Valeria; Modlin, Irvin M.; Pontén, Fredrik; Nilsson, Mats et al.

Part of Neuroendocrinology, p. 16-30, 2013

DOI for Improving the Diagnosis and Management of Neuroendocrine Tumors: Utilizing New Advances in Biomarker and Molecular Imaging Science

Profiling cellular protein complexes by proximity ligation with dual tag microarray readout

Hammond, Maria; Nong, Rachel Yuan; Ericsson, Olle; Pardali, Katerina et al.

Part of PLOS ONE, 2012

Visualising individual sequence-specific protein-DNA interactions in situ

Weibrecht, Irene; Gavrilovic, Milan; Lindbom, Lena; Landegren, Ulf et al.

Part of New Biotechnology, p. 589-598, 2012

DOI for Visualising individual sequence-specific protein-DNA interactions in situ

Opportunities for sensitive plasma proteome analysis

Landegren, Ulf; Vänelid, Johan; Hammond, Maria; Nong, Rachel Yuan et al.

Part of Analytical Chemistry, p. 1824-1830, 2012

DOI for Opportunities for sensitive plasma proteome analysis

Molecular tools for sensitive detection of microvesicles as biomarkers

Kamali-Moghaddam, Masood; Yan, Junhong; Wu, Di; Löf, Liza et al.

Part of Protein Science, p. 164-164, 2012

DOI for Molecular tools for sensitive detection of microvesicles as biomarkers

PCR-Based Multiparametric Assays in Single Cells.

Darmanis, Spyros; Gallant, Caroline; Landegren, Ulf

Part of Clinical Chemistry, p. 1618-1619, 2012

DOI for PCR-Based Multiparametric Assays in Single Cells.

Intercellular variation in signaling through the TGF-β pathway and its relation to cell densityand cell cycle phase

Zieba, Agata; Pardali, Katerina; Söderberg, Ola; Lindbom, Lena et al.

Part of Molecular & Cellular Proteomics, 2012

DOI for Intercellular variation in signaling through the TGF-β pathway and its relation to cell densityand cell cycle phase

Comprehensive catalog of European biobanks

Wichmann, H-Erich; Kuhn, Klaus A.; Waldenberger, Melanie; Schmelcher, Dominik et al.

Part of Nature Biotechnology, p. 795-797, 2011

ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing

Darmanis, Spyros; Nong, Rachel Yuan; Vänelid, Johan; Siegbahn, Agneta et al.

Part of PLOS ONE, 2011

DOI for ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing

Increasing the dynamic range of in situ PLA

Clausson, Carl-Magnus; Allalou, Amin; Weibrecht, Irene; Mahmoudi, Salah et al.

Part of Nature Methods, p. 892-893, 2011

DOI for Increasing the dynamic range of in situ PLA

Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer

Tavoosidana, Gholamreza; Ronquist, Gunnar; Darmanis, Spyros; Yan, Junhong et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 8809-8814, 2011

DOI for Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer

Contributions of the EMERALD project to assessing and improving microarray data quality

Beisvåg, Vidar; Kauffmann, Audrey; Malone, James; Foy, Carole et al.

Part of BioTechniques, p. 27-31, 2011

DOI for Contributions of the EMERALD project to assessing and improving microarray data quality

Western Blotting via Proximity Ligation for High Performance Protein Analysis

Liu, Yanling; Gu, Jijuan; Hagner-McWhirter, Asa; Sathiyanarayanan, Poojahrau et al.

Part of Molecular & Cellular Proteomics, 2011

DOI for Western Blotting via Proximity Ligation for High Performance Protein Analysis

Bright-Field Microscopy Visualization of Proteins and Protein Complexes by In Situ Proximity Ligation with Peroxidase Detection

Zieba, Agata; Wählby, Carolina; Hjelm, Fredrik; Jordan, Lee et al.

Part of Clinical Chemistry, p. 99-110, 2010

DOI for Bright-Field Microscopy Visualization of Proteins and Protein Complexes by In Situ Proximity Ligation with Peroxidase Detection

Sensitive detection of A beta protofibrils by proximity ligation: relevance for Alzheimer's disease

Kamali-Moghaddam, Masood; Ekholm Pettersson, Frida; Wu, Di; Englund, Hillevi et al.

Part of BMC Neuroscience, p. 124, 2010

DOI for Sensitive detection of A beta protofibrils by proximity ligation: relevance for Alzheimer's disease

A Community Standard Format for the Representation of Protein Affinity Reagents

Gloriam, David E.; Orchard, Sandra; Bertinetti, Daniela; Björling, Erik et al.

Part of Molecular & Cellular Proteomics, p. 1-10, 2010

DOI for A Community Standard Format for the Representation of Protein Affinity Reagents

Novel means of viral antigen identification: Improved detection of avian influenza viruses by proximity ligation

Schlingemann, Joerg; Leijon, Mikael; Yacoub, Alia; Schlingemann, Heidi et al.

Part of Journal of Virological Methods, p. 116-122, 2010

DOI for Novel means of viral antigen identification: Improved detection of avian influenza viruses by proximity ligation

High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation

Leuchowius, Karl-Johan; Jarvius, Malin; Wickström, Malin; Rickardson, Linda et al.

Part of Molecular & Cellular Proteomics, p. 178-183, 2010

DOI for High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation

Sensitive plasma protein analysis by microparticle-based proximity ligation assays

Darmanis, Spyros; Nong, Rachel Yuan; Hammond, Maria; Gu, Jijuan et al.

Part of Molecular & Cellular Proteomics, p. 327-335, 2010

DOI for Sensitive plasma protein analysis by microparticle-based proximity ligation assays

Single molecule analysis of combinatorial splicing

Conze, Tim; Göransson, Jenny; Razzaghian, Hamidreza; Ericsson, Olle et al.

Part of Nucleic Acids Research, 2010

DOI for Single molecule analysis of combinatorial splicing

MUC2 mucin is a major carrier of the cancer-associated sialyl-Tn antigen in intestinal metaplasia and gastric carcinomas

Conze, Tim; Carvalho, Ana Sofia; Landegren, Ulf; Almeida, Raquel et al.

Part of Glycobiology, p. 199-206, 2010

DOI for MUC2 mucin is a major carrier of the cancer-associated sialyl-Tn antigen in intestinal metaplasia and gastric carcinomas

Glycosylases and AP-cleaving enzymes as a general tool for probe-directed cleavage of ssDNA targets

Howell, W. Mathias; Grundberg, Ida; Faryna, Marta; Landegren, Ulf et al.

Part of Nucleic Acids Research, 2010

DOI for Glycosylases and AP-cleaving enzymes as a general tool for probe-directed cleavage of ssDNA targets

Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family

Leuchowius, Karl-Johan; Weibrecht, Irene; Landegren, Ulf; Gedda, Lars et al.

Part of Cytometry: Part A, p. 833-839, 2009

DOI for Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family

Multiplex and quantifiable detection of nucleic acid from pathogenic fungi using padlock probes, generic real time PCR and specific suspension array readout

Eriksson, Ronnie; Jobs, Magnus; Ekstrand, Charlotta; Ullberg, Måns et al.

Part of Journal of Microbiological Methods, p. 195-202, 2009

DOI for Multiplex and quantifiable detection of nucleic acid from pathogenic fungi using padlock probes, generic real time PCR and specific suspension array readout

Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia

Massinen, Satu; Tammimies, Kristiina; Tapia-Páez, Isabel; Matsson, Hans et al.

Part of Human Molecular Genetics, p. 2802-2812, 2009

DOI for Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia

Proximity ligation measurement of the complex between prostate specific antigen and alpha1-protease inhibitor

Zhu, Lei; Koistinen, Hannu; Landegren, Ulf; Stenman, Ulf-Håkan

Part of Clinical Chemistry, p. 1665-1671, 2009

DOI for Proximity ligation measurement of the complex between prostate specific antigen and alpha1-protease inhibitor

Selective amplification of mutant DNA: mutations come to light in melting DNA

Landegren, Ulf

Part of Human Mutation, 2009

DOI for Selective amplification of mutant DNA: mutations come to light in melting DNA

Estrogen receptor alpha gene polymorphism and endometrial cancer risk: a case-control study

Wedrén, Sara; Lovmar, Lovisa; Humphreys, Keith; Magnusson, Cecilia et al.

Part of BMC Cancer, p. 322, 2008

DOI for Estrogen receptor alpha gene polymorphism and endometrial cancer risk: a case-control study

Interferon Regulatory Factor 5 (IRF5) Gene Variants are Associated with Multiple Sclerosis in Three Distinct Populations

Kristjansdottir, Gudlaug; Sandling, Johanna K; Bonetti, Alessandro; Roos, Izaura M et al.

Part of Journal of Medical Genetics, p. 362-369, 2008

DOI for Interferon Regulatory Factor 5 (IRF5) Gene Variants are Associated with Multiple Sclerosis in Three Distinct Populations

A dual-tag microarray platform for high-performance nucleic acid and protein analyses

Ericsson, Olle; Jarvius, Jonas; Schallmeiner, Edith; Howell, MAthias et al.

Part of Nucleic Acids Research, 2008

DOI for A dual-tag microarray platform for high-performance nucleic acid and protein analyses

Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay.

Söderberg, Ola; Leuchowius, Karl-Johan; Gullberg, Mats; Jarvius, Malin et al.

Part of Methods, p. 227-32, 2008

DOI for Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay.

Biobanking for Europe

Yuille, Martin; van Ommen, Gert-Jan; Bréchot, Christian; Cambon-Thomsen, Anne et al.

Part of Briefings in Bioinformatics, p. 14-24, 2008

DOI for Biobanking for Europe

Use of Proximity Ligation to Screen for Inhibitors of Interactions between Vascular Endothelial Growth Factor A and Its Receptors

Gustafsdottir, Sigrun M; Wennström, Stefan; Fredriksson, Simon; Schallmeiner, Edith et al.

Part of Clinical Chemistry, p. 1218-1225, 2008

DOI for Use of Proximity Ligation to Screen for Inhibitors of Interactions between Vascular Endothelial Growth Factor A and Its Receptors

Evaluation of a novel proximity ligation assay for the sensitive and rapid detection of foot-and-mouth disease virus

Nordengrahn, Ann; Gustafsdottir, Sigrun M.; Ebert, Katja; Reid, Scott M. et al.

Part of Veterinary Microbiology, p. 227-236, 2008

DOI for Evaluation of a novel proximity ligation assay for the sensitive and rapid detection of foot-and-mouth disease virus

Novel and highly recurrent chromosomal alterations in Sézary syndrome

Vermeer, Maarten H; van Doorn, Remco; Dijkman, Remco; Mao, Xin et al.

Part of Cancer Research, p. 2689-2698, 2008

DOI for Novel and highly recurrent chromosomal alterations in Sézary syndrome

Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.

Szado, Tania; Vanderheyden, Veerle; Parys, Jan B; De Smedt, Humbert et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 2427-2432, 2008

DOI for Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.

Simultaneous genotyping of all hemagglutinin and neuraminidase subtypes of avian influenza viruses by use of padlock probes

Gyarmati, Péter; Conze, Tim; Zohari, Siamak; LeBlanc, Neil et al.

Part of Journal of Clinical Microbiology, p. 1747-1751, 2008

DOI for Simultaneous genotyping of all hemagglutinin and neuraminidase subtypes of avian influenza viruses by use of padlock probes

Ligation-based molecular tools for lab-on-a-chip devices

Melin, Jonas; Jarvius, Jonas; Larsson, Chatarina; Söderberg, Ola et al.

Part of New Biotechnology, p. 42-8, 2008

DOI for Ligation-based molecular tools for lab-on-a-chip devices

In vitro analysis of DNA-protein interactions by proximity ligation

Gustafsdottir, Sigrun M.; Schlingemann, Jörg; Rada-Iglesias, Alvaro; Schallmeiner, Edith et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 3067-3072, 2007

DOI for In vitro analysis of DNA-protein interactions by proximity ligation

Evaluation of beta globin mRNA as an early marker of haemoglobin response to epoetin treatment

Birgegård, Gunnar; Dahl, Fredrik; Glimelius, Bengt; Landegren, Ulf

Part of Medical Oncology, p. 318-322, 2007

DOI for Evaluation of beta globin mRNA as an early marker of haemoglobin response to epoetin treatment

Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development

Abramsson, Alexandra; Kurup, Sindhulakshmi; Yamada, Shuhei; Lindblom, Per et al.

Part of Genes & Development, p. 316-331, 2007

DOI for Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development

ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

Taussig, Michael J.; Stoevesandt, Oda; Borrebaeck, Carl A. K.; Bradbury, Andrew R. et al.

Part of Nature Methods, p. 13-17, 2007

DOI for ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

Self-assembly of proximity probes for flexible and modular proximity ligation assays

Darmanis, Spyros; Kähler, Anna; Spångberg, Lena; Kamali-Moghaddam, Masood et al.

Part of BioTechniques, p. 443-450, 2007

DOI for Self-assembly of proximity probes for flexible and modular proximity ligation assays

In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method

Jarvius, Malin; Paulsson, Janna; Weibrecht, Irene; Leuchowius, Karl-Johan et al.

Part of Molecular & Cellular Proteomics, p. 1500-1509, 2007

DOI for In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method

Sensitive protein detection via triple-binder proximity ligation assays

Schallmeiner, Edith; Oksanen, Elli; Ericsson, Olle; Spångberg, Lena et al.

Part of Nature Methods, p. 135-137, 2007

DOI for Sensitive protein detection via triple-binder proximity ligation assays

Microarray-based molecular detection of foot-and-mouth disease, vesicular stomatitis and swine vesicular disease viruses, using padlock probes

Banér, Johan; Gyarmati, Péter; Yacoub, Alia; Hakhverdyan, Mikhayil et al.

Part of Journal of Virological Methods, p. 200-206, 2007

DOI for Microarray-based molecular detection of foot-and-mouth disease, vesicular stomatitis and swine vesicular disease viruses, using padlock probes

Detection of individual microbial pathogens by proximity ligation

Gustafsdottir, Sigrun M.; Nordengrahn, Ann; Fredriksson, Simon; Wallgren, Per et al.

Part of Clinical Chemistry, p. 1152-1160, 2006

DOI for Detection of individual microbial pathogens by proximity ligation

DNA Skyline: fonts to facilitate visual inspection of nucleic acid sequences

Jarvius, Jonas; Landegren, Ulf

Part of BioTechniques, p. 740, 2006

DOI for DNA Skyline: fonts to facilitate visual inspection of nucleic acid sequences

Direct observation of individual endogenous protein complexes in situ by proximity ligation

Söderberg, Ola; Gullberg, Mats; Jarvius, Malin; Ridderstråle, Karin et al.

Part of Nature Methods, p. 995-1000, 2006

DOI for Direct observation of individual endogenous protein complexes in situ by proximity ligation

Molecular markers for discrimination of benign and malignant follicular thyroid tumors

Fryknäs, Mårten; Wickenberg Bolin, Ulrika; Göransson, Hanna; Gustafsson, Mats G et al.

Part of Tumor Biology, p. 211-220, 2006

DOI for Molecular markers for discrimination of benign and malignant follicular thyroid tumors

A sensitive proximity ligation assay for active PSA.

Zhu, undefined; Koistinen, undefined; Wu, undefined; Närvänen, undefined et al.

Part of Biol Chem, p. 769-72, 2006

[Molecular medicine tools. Future prospects with new techniques]

Landegren, Ulf; Kamali-Moghaddam, Masood; Nilsson, Mats

Part of Lakartidningen, p. 2947-52, 2006

PieceMaker: selection of DNA fragments for selector-guided multiplex amplification

Stenberg, Johan; Dahl, Fredrik; Landegren, Ulf; Nilsson, Mats

Part of Nucleic Acids Research, 2005

ProbeMaker: an extensible framework for design of sets of oligonucleotide probes

Stenberg, Johan; Nilsson, Mats; Landegren, Ulf

Part of BMC Bioinformatics, p. 229, 2005

DOI for ProbeMaker: an extensible framework for design of sets of oligonucleotide probes

Thermoplastic microfluidic platform for single-molecule detection, cell culture and actuation

Melin, Jonas; Johansson, Henrik; Söderberg, Ola; Nikolajeff, Fredrik et al.

Part of Analytical Chemistry, p. 7122-30, 2005

DOI for Thermoplastic microfluidic platform for single-molecule detection, cell culture and actuation

Analysis of T-Cell Receptor V{beta} Gene Repertoires after Immune Stimulation and in Malignancy by Use of Padlock Probes and Microarrays.

Banér, Johan; Marits, Per; Nilsson, Mats; Winqvist, Ola et al.

Part of Clin Chem, p. 768-75, 2005

Oestrogen receptor alpha gene haplotype and postmenopausal breast cancer risk: a case control study

Wedrén, Sara; Lovmar, Lovisa; Humphreys, Keith; Magnusson, Cecilia et al.

Part of Breast Cancer Research, 2004

DOI for Oestrogen receptor alpha gene haplotype and postmenopausal breast cancer risk: a case control study

Molecular tools for a molecular medicine: analyzing genes, transcripts and proteins using padlock and proximity probes

Landegren, Ulf; Schallmeiner, Edith; Nilsson, Mats; Fredriksson, Simon et al.

Part of Journal of Molecular Recognition, p. 194-7, 2004

DOI for Molecular tools for a molecular medicine: analyzing genes, transcripts and proteins using padlock and proximity probes

Cytokine detection by antibody-based proximity ligation

Gullberg, Mats; Gústafsdóttir, Sigrun M.; Schallmeiner, Edith; Jarvius, Jonas et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 8420-4, 2004

DOI for Cytokine detection by antibody-based proximity ligation

In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes.

Larsson, Chatarina; Koch, undefined; Nygren, undefined; Janssen, undefined et al.

Part of Nat Methods, p. 227-232, 2004

Circle-to-circle amplification for precise and sensitive DNA analysis.

Dahl, Fredrik; Banér, Johan; Gullberg, Mats; Mendel-Hartvig, Maritha et al.

Part of Proc Natl Acad Sci U S A, p. 4548-53, 2004

Oligonucleotide ligation assay

Jarvius, Jonas; Nilsson, Mats; Landegren, Ulf

Part of Methods in Molecular Biology, p. 215-28, 2003

Padlock and proximity probes for in situ and array-based analyses: tools for the post genomic era

Landegren, Ulf; Dahl, Fredrik; Nilsson, Mats; Fredriksson, Simon et al.

Part of Comparative and functional genomics, p. 525-30, 2003

DOI for Padlock and proximity probes for in situ and array-based analyses: tools for the post genomic era

Parallel gene analysis with allele-specific padlock probes and tag microarrays

Banér, Johan; Isaksson, Anders; Waldenström, Erik; Jarvius, Jonas et al.

Part of Nucleic Acids Research, 2003

Multiplexed genotyping with sequence-tagged molecular inversion probes

Hardenbol, Paul; Banér, Johan; Jain, Maneesh; Nilsson, Mats et al.

Part of Nature Biotechnology, p. 673-8, 2003

DOI for Multiplexed genotyping with sequence-tagged molecular inversion probes

Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall.

Lindblom, Per; Gerhardt, Holger; Liebner, Stefan; Abramsson, Alexandra et al.

Part of Genes Dev, p. 1835-40, 2003

Protein detection using proximity-dependent DNA ligation assays

Fredriksson, Simon; Gullberg, Mats; Jarvius, Jonas; Olsson, Charlotta et al.

Part of Nature Biotechnology, p. 473-477, 2002

DOI for Protein detection using proximity-dependent DNA ligation assays

A distinct Th1 immune response precedes the described Th2 response in Islet xenograft rejection

Krook, Henrik; Hagberg, Anette; Song, Zhenshung; Landegren, Ulf et al.

Part of Diabetes, p. 79-86, 2002

DOI for A distinct Th1 immune response precedes the described Th2 response in Islet xenograft rejection

PCR-generated padlock probes detect single nucleotide variation in genomic DNA

Antson, D.O.; Isaksson, A.; Landegren, Ulf; Nilsson, Mats

Part of Nucleic Acids Research, 2000

X-linked recessive panhypopituitarism associated with a regional duplication in Xq25-q26

Lagerström-Fermér, Maria; Sundvall, Mats; Johnsen, Elsy; Warne, GL et al.

Part of American Journal of Human Genetics, p. 910-916, 1997

Amelogenin signal peptide mutation: correlation between mutations in the amelogenin gene (AMGX) and manifestations of X-linked amelogenesis imperfecta

Lagerström-Fermér, Maria; Nilsson, Mats; Backman, B; Salido, E et al.

Part of Genomics, p. 159-162, 1995

DOI for Amelogenin signal peptide mutation: correlation between mutations in the amelogenin gene (AMGX) and manifestations of X-linked amelogenesis imperfecta

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