Bengt Westermark

p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics

Niklasson, Mia; Dalmo, Erika; Segerman, Anna; Rendo, Veronica et al.

Part of International Journal of Molecular Sciences, 2025

• DOI for p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics
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Special issue: frontiers in recent advances on cancer diagnosis and treatment

Westermark, Bengt; Heldin, Carl-Henrik

Part of Upsala Journal of Medical Sciences, 2024

• DOI for Special issue: frontiers in recent advances on cancer diagnosis and treatment
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Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Gupta, Rajesh Kumar; Niklasson, Mia; Bergström, Tobias; Segerman, Anna et al.

Part of Scientific Reports, 2024

• DOI for Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain
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Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Ramachandran, Mohanraj; Vaccaro, Alessandra; van de Walle, Tiarne; Georganaki, Maria et al.

Part of Cancer Cell, p. 1134-1151, 2023

• DOI for Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
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Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

Ilkhanizadeh, Shirin; Gracias, Aileen; Aslund, Andreas K. O.; Back, Marcus et al.

Part of ACS Applied Bio Materials, p. 3790-3797, 2023

• DOI for Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
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p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics

Niklasson, Mia; Dalmo, Erika; Segerman, Anna; Rendo, Veronica et al.

Part of International Journal of Molecular Sciences, 2025

• DOI for p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics
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Special issue: frontiers in recent advances on cancer diagnosis and treatment

Westermark, Bengt; Heldin, Carl-Henrik

Part of Upsala Journal of Medical Sciences, 2024

• DOI for Special issue: frontiers in recent advances on cancer diagnosis and treatment
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Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Gupta, Rajesh Kumar; Niklasson, Mia; Bergström, Tobias; Segerman, Anna et al.

Part of Scientific Reports, 2024

• DOI for Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain
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Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Ramachandran, Mohanraj; Vaccaro, Alessandra; van de Walle, Tiarne; Georganaki, Maria et al.

Part of Cancer Cell, p. 1134-1151, 2023

• DOI for Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
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Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

Ilkhanizadeh, Shirin; Gracias, Aileen; Aslund, Andreas K. O.; Back, Marcus et al.

Part of ACS Applied Bio Materials, p. 3790-3797, 2023

• DOI for Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
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Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Dalmo, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Part of Molecular Systems Biology, 2021

• DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
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A human cell type similar to murine central nervous system perivascular fibroblasts

Liu, Jianping; He, Liqun; Muhl, Lars; Mocci, Giuseppe et al.

Part of Experimental Cell Research, 2021

• DOI for A human cell type similar to murine central nervous system perivascular fibroblasts
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Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Lundin, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Part of Molecular Systems Biology, 2021

• DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
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Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

Dalmo, Erika; Johansson, Patrik; Niklasson, Mia; Gustavsson, Ida et al.

Part of Molecular Cancer Research, p. 981-991, 2020

• DOI for Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Cancer, Matko; Drews, Lisa F.; Bengtsson, Johan; Bolin, Sara et al.

Part of Cell Death and Disease, 2019

• DOI for BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
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Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors

Kaffes, Ioannis; Szulzewsky, Frank; Chen, Zhihong; Herting, Cameron J. et al.

Part of Oncoimmunology, 2019

• DOI for Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
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Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity

Niklasson, Mia; Bergström, Tobias; Jarvius, Malin; Sundström, Anders et al.

Part of Journal of Pathology, p. 295-307, 2019

• DOI for Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

Part of Acta Oncologica, p. 187-194, 2018

• DOI for U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
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Mast cells modulate proliferation, migration and sternness of glioma cells through downregulation of GSK3 beta expression and inhibition of STAT3 activation

Attarha, Sanaz; Roy, Ananya; Westermark, Bengt; Tchougounova, Elena

Part of Cellular Signalling, p. 81-92, 2017

• DOI for Mast cells modulate proliferation, migration and sternness of glioma cells through downregulation of GSK3 beta expression and inhibition of STAT3 activation

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Darmanis, Spyros; Gallant, Caroline Julie; Marinescu, Voichita Dana; Niklasson, Mia et al.

Part of Cell Reports, p. 380-389, 2016

• DOI for Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
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Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

Segerman, Anna; Niklasson, Mia; Haglund, Caroline; Bergström, Tobias et al.

Part of Cell Reports, p. 2994-3009, 2016

• DOI for Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
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Case-specific potentiation of glioblastoma drugs by pterostilbene

Schmidt, Linnéa; Baskaran, Sathishkumar; Johansson, Patrik; Padhan, Narendra et al.

Part of Oncotarget, p. 73200-73215, 2016

• DOI for Case-specific potentiation of glioblastoma drugs by pterostilbene

ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells

Wee, Boyoung; Pietras, Alexander; Ozawa, Tatsuya; Bazzoli, Elena et al.

Part of Scientific Reports, 2016

• DOI for ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells
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Origin of the U87MG glioma cell line: Good news and bad news

Allen, Marie; Bjerke, Mia; Edlund, Hanna; Nelander, Sven et al.

Part of Science Translational Medicine, 2016

• DOI for Origin of the U87MG glioma cell line: Good news and bad news

Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs

Agarwal, Prasoon; Enroth, Stefan; Teichmann, Martin; Jernberg Wiklund, Helena et al.

Part of Cell Cycle, p. 1558-1571, 2016

• DOI for Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs
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CGGBP1 mitigates cytosine methylation at repetitive DNA sequences

Agarwal, Prasoon; Collier, Paul; Fritz, Markus Hsi-Yang; Benes, Vladimir et al.

Part of BMC Genomics, 2015

• DOI for CGGBP1 mitigates cytosine methylation at repetitive DNA sequences
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Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

Roy, Ananya; Coum, Antoine; Marinescu, Voichita D; Põlajeva, Jelena et al.

Part of Oncotarget, p. 23647-23661, 2015

• DOI for Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
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The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

Xie, Yuan; Bergström, Tobias; Jiang, Yiwen; Johansson, Patrik et al.

Part of EBioMedicine, p. 1351-1363, 2015

• DOI for The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes
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Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from Human glioblastoma

Babateen, Omar; Jin, Zhe; Bhandage, Amol K.; Korol, Sergiy V et al.

Part of European Journal of Pharmacology, p. 101-107, 2015

• DOI for Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from Human glioblastoma

GABA-A receptor currents in a cell line (U3047MG) derived from a human glioblastoma tumor are enhanced by etomidate, propofol and diazepam

Babateen, Omar M.; Jin, Zhe; Bhandage, Amol K.; Korol, Sergiy V. et al.

Part of Acta Physiologica, p. 100-100, 2014

U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells

Torsvik, Anja; Stieber, Daniel; Enger, Per Oyvind; Golebiewska, Anna et al.

Part of Cancer Medicine, p. 812-824, 2014

• DOI for U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells
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Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner

Põlajeva, Jelena; Bergström, Tobias; Edqvist, Per-Henrik; Lundequist, Anders et al.

Part of Molecular Oncology, p. 50-58, 2014

• DOI for Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner

Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells

Wee, Shimei; Niklasson, Maria; Marinescu, Voichita Dana; Segerman, Anna et al.

Part of PLOS ONE, 2014

• DOI for Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells
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Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

Kitambi, Satish Srinivas; Toledo, Enrique M.; Usoskin, Dmitry; Wee, Shimei et al.

Part of Cell, p. 313-328, 2014

• DOI for Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

Taming the cancer cell: Introduction

Jernberg Wiklund, Helena; Westermark, Bengt

Part of Journal of Internal Medicine, p. 2-4, 2014

• DOI for Taming the cancer cell: Introduction

CGGBP1 phosphorylation constitutes a telomere-protection signal

Singh, Umashankar; Maturi, Varun; Jones, Rhiannon E; Paulsson, Ylva et al.

Part of Cell Cycle, p. 96-105, 2014

• DOI for CGGBP1 phosphorylation constitutes a telomere-protection signal

Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

Yu, Di; Jin, Chuan; Ramachandran, Mohanraj; Xu, Jing et al.

Part of PLOS ONE, 2013

• DOI for Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
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Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions

Schmidt, Linnea; Kling, Teresia; Monsefi, Naser; Olsson, Maja et al.

Part of Neuro-Oncology, p. 1469-1478, 2013

• DOI for Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions

Sox21 inhibits glioma progression in vivo by reducing Sox2 and stimulating aberrant differentiation

Caglayan, Demet; Lundin, Erika; Kastemar, Marianne; Westermark, Bengt et al.

Part of International Journal of Cancer, p. 1345-1356, 2013

• DOI for Sox21 inhibits glioma progression in vivo by reducing Sox2 and stimulating aberrant differentiation

Evidence for multiple forms and modifications of human POT1

Singh, Umashankar; Maturi, Varun; Westermark, Bengt

Part of DNA Repair, p. 876-877, 2013

• DOI for Evidence for multiple forms and modifications of human POT1

Sox21 inhibits glioma progression in vivo by forming complexes with Sox2 and stimulating aberrant differentiation

Caglayan, Demet; Lundin, Erika; Kastemar, Marianne; Westermark, Bengt et al.

Part of International Journal of Cancer, p. 1345-1356, 2013

• DOI for Sox21 inhibits glioma progression in vivo by forming complexes with Sox2 and stimulating aberrant differentiation

miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma

Põlajeva, Jelena; Swartling, Fredrik; Jiang, Yiwen; Singh, Umashankar et al.

Part of BMC Cancer, p. 378, 2012

• DOI for miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma
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Induced Expression of Sox21 Inhibits Glioma Progression in Vivo by Stimulating Aberrant Differentiation

Ferletta, Maria; Caglayan, Demet; Lundin, Erika; Kastemar, Marianne et al.

Part of European Journal of Cancer, 2012

• DOI for Induced Expression of Sox21 Inhibits Glioma Progression in Vivo by Stimulating Aberrant Differentiation

CGGBP1 regulates cell cycle in cancer cells

Singh, Umashankar; Roswall, Pernilla; Uhrbom, Lene; Westermark, Bengt

Part of BMC Molecular Biology, p. 28, 2011

• DOI for CGGBP1 regulates cell cycle in cancer cells
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PDGF-B Can sustain self-renewal and tumorigenicity of experimental glioma-derived cancer-initiating cells by preventing oligodendrocyte differentiation

Jiang, Yiwen; Boije, Maria; Westermark, Bengt; Uhrbom, Lene

Part of Neoplasia, p. 492-503, 2011

• DOI for PDGF-B Can sustain self-renewal and tumorigenicity of experimental glioma-derived cancer-initiating cells by preventing oligodendrocyte differentiation

Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells

Ferletta, Maria; Caglayan, Demet; Mokvist, Liza; Yiwen, Jiang et al.

Part of International Journal of Cancer, p. 45-60, 2011

• DOI for Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells

Mast Cell Accumulation in Glioblastoma with a Potential Role for Stem Cell Factor and Chemokine CXCL12

Põlajeva, Jelena; Sjösten, Anna M; Lager, Nina; Kastemar, Marianne et al.

Part of PLOS ONE, 2011

• DOI for Mast Cell Accumulation in Glioblastoma with a Potential Role for Stem Cell Factor and Chemokine CXCL12
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CGGBP1 is a nuclear and midbody protein regulating abscission

Singh, Umashankar; Westermark, Bengt

Part of Experimental Cell Research, p. 143-150, 2011

• DOI for CGGBP1 is a nuclear and midbody protein regulating abscission

Investigation of gene dosage imbalances in patients with Noonan syndrome using multiplex ligation-dependent probe amplification analysis

Nyström, Anna-Maja; Ekvall, Sara; Thuresson, Ann-Charlotte; Kamali-Moghaddam, Masood et al.

Part of European Journal of Medical Genetics, p. 117-121, 2010

• DOI for Investigation of gene dosage imbalances in patients with Noonan syndrome using multiplex ligation-dependent probe amplification analysis

Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines

Swartling, Fredrik J.; Ferletta, Maria; Kastemar, Marianne; Weiss, W. A. et al.

Part of Oncogene, p. 3121-3131, 2009

• DOI for Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines

A DNA sequence directed mutual transcription regulation of HSF1 and NFIX involves novel heat sensitive protein interactions

Singh, Umashankar; Bongcam-Rudloff, Erik; Westermark, Bengt

Part of PLoS ONE, 2009

• DOI for A DNA sequence directed mutual transcription regulation of HSF1 and NFIX involves novel heat sensitive protein interactions

Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence

Tchougounova, Elena; Jiang, Yiwen; Bråsäter, Daniel; Lindberg, Nanna et al.

Part of Oncogene, p. 1537-1548, 2009

• DOI for Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence

Herbal melanin activates TLR4/NF-kappaB signaling pathway

Öberg, Fredrik; Haseeb, Adil; Ahnfelt, Matilda; Pontén, Fredrik et al.

Part of Phytomedicine, p. 477-84, 2009

• DOI for Herbal melanin activates TLR4/NF-kappaB signaling pathway

GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background

Hede, Sanna-Maria; Hansson, Inga; Afink, Gijs B; Eriksson, Anna et al.

Part of Glia, p. 1143-1153, 2009

• DOI for GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background

Sox10 Has a Broad Expression Pattern in Gliomas and Enhances Platelet-Derived Growth Factor-B–Induced Gliomagenesis

Ferletta, Maria; Uhrbom, Lene; Olofsson, Tommie; Pontén, Fredrik et al.

Part of Molecular Cancer Research, p. 891-897, 2007

• DOI for Sox10 Has a Broad Expression Pattern in Gliomas and Enhances Platelet-Derived Growth Factor-B–Induced Gliomagenesis

Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma

Tchougounova, Elena; Kastemar, Marianne; Bråsäter, Daniel; Holland, E C et al.

Part of Oncogene, p. 6289-6296, 2007

• DOI for Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma

Autocrine/Paracrine platelet-derived growth factor regulates proliferation of neural progenitor cells

Erlandsson, Anna; Brännvall, Karin; Gustafsdottir, Sigrun; Westermark, Bengt et al.

Part of Cancer Research, p. 8042-8048, 2006

• DOI for Autocrine/Paracrine platelet-derived growth factor regulates proliferation of neural progenitor cells

Effect of herbal melanin on IL-8: a possible role of Toll-like receptor 4 (TLR4).

El-Obeid, Adila; Hassib, Adil; Pontén, Fredrik; Westermark, Bengt

Part of Biochem Biophys Res Commun, p. 1200-6, 2006

Expression analysis of genes involved in brain tumor progression driven by retroviral insertional mutagenesis in mice

Johansson, Fredrik K; Göransson, Hanna; Westermark, Bengt

Part of Oncogene, p. 3896-3905, 2005

• DOI for Expression analysis of genes involved in brain tumor progression driven by retroviral insertional mutagenesis in mice

Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis.

Uhrbom, Lene; Kastemar, Marianne; Johansson, Fredrik K; Westermark, Bengt et al.

Part of Cancer Res, p. 2065-9, 2005

Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging

Johansson, Fredrik K.; Brodd, Josefin; Eklöf, Charlotta; Ferletta, Maria et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 11334-11337, 2004

• DOI for Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging

Soluble factors released by virus specific activated cytotoxicT-lymphocytes induce apoptotic death of astroglioma cell lines

Sabri, Farideh; Chiodi, Francesca; Piret, Jean-Pascal; Wei, Cheng-Hong et al.

Part of Brain Pathology, p. 165-175, 2003

• DOI for Soluble factors released by virus specific activated cytotoxicT-lymphocytes induce apoptotic death of astroglioma cell lines

p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3.

Wolf, Rebecca M.; Draghi, Nicole; Liang, Xiquan; Dai, Chengkai et al.

Part of Development, Genes and Evolution, p. 476-487, 2003

• DOI for p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3.

Oligodendrocyte precursor hypercellularity and abnormal retina development in mice overexpressing PDGF-B in myelinating tracts

Forsberg-Nilsson, Karin; Erlandsson, Anna; Zhang, Xiao-Qun; Ueda, Hideho et al.

Part of Glia, p. 276-89, 2003

• DOI for Oligodendrocyte precursor hypercellularity and abnormal retina development in mice overexpressing PDGF-B in myelinating tracts

Complementary effects of platelet-derived growth factor autocrine stimulation and p53 or Ink4a-Arf deletion in a mouse glioma model.

Hesselager, Göran; Uhrbom, Lene; Westermark, Bengt; Nister, Monica

Part of Cancer Research, p. 4305, 2003

TGF-alpha-driven tumor growth is inhibited by an EGF receptor tyrosine kinase inhibitor

El-Obeid, A.; Hesselager, Göran; Westermark, Bengt; Nister, M.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 349-58, 2002

• DOI for TGF-alpha-driven tumor growth is inhibited by an EGF receptor tyrosine kinase inhibitor

A 1.8kb GFAP-promoter fragment is active in specific regions of theembryonic CNS

Andrae, Johanna; Bongcam-Rudloff, Erik; Hansson, Inga; Lendahl, Urban et al.

Part of Mechanisms of Development, p. 181-5, 2001

• DOI for A 1.8kb GFAP-promoter fragment is active in specific regions of theembryonic CNS

Expression of different phenotypes in cell lines from canine mammary spindle-cell tumours and osteosarcomas indicating a pluripotent mammary stem cell origin

Hellmen, Eva; Moller, Maria; Blankenstein, Marinus A.; Andersson, Leif et al.

Part of Breast Cancer Research and Treatment, p. 197-210, 2000

• DOI for Expression of different phenotypes in cell lines from canine mammary spindle-cell tumours and osteosarcomas indicating a pluripotent mammary stem cell origin

Epidermal growth factor receptor signaling activates Met in human anaplastic thyroid carcinoma cells

Bergström, J.Daniel; Westermark, Bengt; Heldin, Nils-Erik

Part of Experimental Cell Research, p. 293-299, 2000

• DOI for Epidermal growth factor receptor signaling activates Met in human anaplastic thyroid carcinoma cells

PDGF B mRNA variants in human tumors with similarity to the v-sis oncogene: Expression of cellular PDGF B protein is associated with exon 1 divergence, but not with a 3'UTR splice variant

Heller, Susanne; Scheibenpflug, Lena; Westermark, Bengt; Nistér, Monica

Part of Int J Cancer, p. 211-222, 2000

Dependence of autocrine growth factor stimulation in platelet-derived growth factor-B-induced mouse brain tumor cells

Uhrbom, Lene; Hesselager, Göran; Östman, Arne; Nistér, Monica et al.

Part of Int J Cancer, p. 398-406, 2000

Modulation of phenotype and induction of irregular vessels accompany high tumorigenic potential of clonal human glioma cells xenografted to nude-rat brain

Enblad, Per; Hesselager, Göran; Bongcam-Rudloff, Erik; Hallin, Inga et al.

Part of Int J Cancer, p. 819-828, 2000

Expression of transforming growth factor-beta1, activin A, and their receptors in thyroid follicle cells: negative regulation of thyrocyte growth and function.

Franzén, Åsa; Piek, Ester; Westermark, Bengt; ten Dijke, Peter et al.

Part of Endocrinology, p. 4300, 1999

Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene

Zhang, Xiao-Qun; Afink, Gijs; Svensson, Kristian; Jacobs, Jacqueline J.L. et al.

Part of Mechanisms of Development, p. 167-180, 1998

• DOI for Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene

Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members

Afrakhte, Mozhgan; Morén, Anita; Jossan, Surinder; Itoh, Susumu et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 505-11, 1998

• DOI for Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members

Induction of brain tumors in mice using a recombinant PDGF B retrovirus

Uhrbom, Lene; Hesselager, Göran; Nister, Monica; Westermark, Bengt

Part of Cancer Research, p. 5275-5279, 1998

Induction of senescence in human malignant glioma cells by p16INK4A

Uhrbom, Lene; Nister, Monica; Westermark, Bengt

Part of Oncogene, p. 111, 1997

Production of cell-associated PDGF-AA by a human sarcoma cell line: Evidence for a latent autocrine effect

Afrakhte, M; Nistér, M; Östman, A; Westermark, B et al.

Part of Int J Cancer, p. 802-809, 1996

Luteal failure in transgenic mice carrying a PDGF dominant-negative mutant/GH hybrid transgene

Pekny, Milos; Pekna, M; Östman, A; Törnell, J et al.

Part of Transgenics (Basel. Print), p. 515-523, 1995

Detection of TP53 gene mutation in human meningiomas: A study using immunohistochemistry, polymerase chain reaction/single-strand conformation polymorphism and DNA sequencing techniques on paraffin-embedded samples

Wang, J-L; Zhang, Z-J; Hartman, M; Smits, A et al.

Part of Int J Cancer, p. 223-228, 1995

Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes

Heldin, Carl-Henrik; Östman, Arne; Eriksson, Anders; Siegbahn, Agneta et al.

Part of Kidney International, p. 571-574, 1992

• DOI for Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes

Expression of platelet-derived growth factor and its receptors in proliferative disorders of fibroblastic origin

Smits, Anja; Funa, K; Vassbotn, F S; Beausang-Linder, M et al.

Part of American Journal of Pathology, p. 639-648, 1992

Differential effects of platelet-derived growth factors on fetal hippocampal and cortical grafts: evidence from intraocular transplantation in rats

Giacobini, MaiBritt M J; Smits, Anja; Funa, K; Westermark, B et al.

Part of Neuroscience Letters, p. 227-231, 1992

• DOI for Differential effects of platelet-derived growth factors on fetal hippocampal and cortical grafts: evidence from intraocular transplantation in rats

Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis

Blume-Jensen, Peter; Claesson-Welsh, Lena; Siegbahn, Agneta; Zsebo, Krisztina M. et al.

Part of EMBO Journal, p. 4121-4128, 1991

Neurotrophic activity of platelet-derived growth factor (PDGF): Rat neuronal cells possess functional PDGF beta-type receptors and respond to PDGF

Smits, Anja; Kato, M; Westermark, Bengt; Nistér, M et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 8159-8163, 1991

Rat brain capillary endothelial cells express functional PDGF B-type receptors

Smits, Anja; Hermansson, M; Nistér, M; Karnushina, I et al.

Part of Growth Factors, p. 1-8, 1989

A glioma-derived PDGF A chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets.

Nistér, M; Hammacher, A; Mellström, K; Siegbahn, A et al.

Part of Cell, p. 791-9, 1988

Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis

Heldin, Carl-Henrik; Lennartsson, Johan; Westermark, Bengt

Part of Journal of Internal Medicine, p. 16-44, 2018

• DOI for Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis

CGGBP1-an indispensable protein with ubiquitous cytoprotective functions

Singh, Umashankar; Westermark, Bengt

Part of Upsala Journal of Medical Sciences, p. 219-232, 2015

• DOI for CGGBP1-an indispensable protein with ubiquitous cytoprotective functions

Platelet-derived growth factor in glioblastoma-driver or biomarker?

Westermark, Bengt

Part of Upsala Journal of Medical Sciences, p. 298-305, 2014

• DOI for Platelet-derived growth factor in glioblastoma-driver or biomarker?

Glioblastoma: a moving target

Westermark, Bengt

Part of Upsala Journal of Medical Sciences, p. 251-256, 2012

• DOI for Glioblastoma: a moving target

Glial tumors of the CNS

Nistér, Monica; Uhrbom, Lene; Hesselager, Göran; Westermark, Bengt

Part of Glial Cell Development, p. 437, Oxford University Press, 2001

BMP4 induction of a senescence-like phenotype in human glioblastoma cells is dependent on p21

Niklasson, Mia; Dalmo, Erika; Westermark, Bengt

Targeting SOX2 in glioblastoma cells reveals heterogeneity in SOX2 dependency

Dalmo, Erika; Rosén, Gabriela; Niklasson, Mia; Bergström, Tobias et al.

BMP4 induces a p21-dependent cell state shift in glioblastoma linking mesenchymal transition to senescence

Niklasson, Mia; Dalmo, Erika; Segerman, Anna; Rendo, Verónica et al.

• DOI for BMP4 induces a p21-dependent cell state shift in glioblastoma linking mesenchymal transition to senescence

RAP1GAP Suppression Promotes Stemness and Inhibits Glioblastoma Cell Migration

Põlajeva, Jelena; Kastemar, Marianne; Tchougounova, Elena; Zeller, Kathrin et al.