Agneta Siegbahn

Evaluation of the updated ABC-AF-bleeding score 2.0 in patients with atrial fibrillation treated with a direct oral anticoagulant or warfarin

Hijazi, Ziad; Lindbäck, Johan; Oldgren, Jonas; Alexander, John H. et al.

Part of Journal of Thrombosis and Haemostasis, p. 399-407, 2026

DOI for Evaluation of the updated ABC-AF-bleeding score 2.0 in patients with atrial fibrillation treated with a direct oral anticoagulant or warfarin
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Plasma Biomarkers Associated With Heart Failure Hospitalization Among Patients With Atrial Fibrillation and Subtypes of Heart Failure

Pol, Tymon; Lindbäck, Johan; Oldgren, Jonas; Alexander, John H. et al.

Part of Journal of the American Heart Association, 2026

Plasma-Derived Extracellular Vesicle-Propagated microRNA From Aortic Stenosis Patients Render Pro-Calcifying Effects on Valve Interstitial Cells

Khandagale, Avinash B.; Corcoran, Pádraic; Dan, Yuzhen; Isaksson, Anders et al.

Part of JACC: Basic to Translational Science, 2025

Correction to: C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes.

Andersen, Thomas; Ueland, Thor; Ghukasyan Lakic, Tatevik; Åkerblom, Axel et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, 2025

DOI for Correction to: C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes.

Correction to: C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes.

Andersen, Thomas; Ueland, Thor; Lakic, Tatevik; Åkerblom, Axel et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, 2025

DOI for Correction to: C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes.

Mosaic loss of Y chromosome and mortality after coronary angiography

Weyrich, Michael; Zewinger, Stephen; Sarakpi, Tamim; Rasper, Tina et al.

Part of European Heart Journal, p. 1603-1616, 2025

Biomarker-Based Model for Prediction of Ischemic Stroke in Patients With Atrial Fibrillation

Wallentin, Lars; Lindbäck, Johan; Hijazi, Ziad; Oldgren, Jonas et al.

Part of Journal of the American College of Cardiology, 2025

DOI for Biomarker-Based Model for Prediction of Ischemic Stroke in Patients With Atrial Fibrillation

Associations between psychosocial burden and prognostic biomarkers in patients with chronic coronary syndrome: a STABILITY substudy

Wassberg, Charlotte; Batra, Gorav; Hadziosmanovic, Nermin; Hagström, Emil et al.

Part of European Journal of Preventive Cardiology, p. 456-465, 2024

Repeated Measurement of the Novel Atrial Biomarker BMP10 (Bone Morphogenetic Protein 10) Refines Risk Stratification in Anticoagulated Patients With Atrial Fibrillation: Insights From the ARISTOTLE Trial

Gkarmiris, Konstantinos I.; Lindbäck, Johan; Alexander, John H.; Granger, Christopher B. et al.

Part of Journal of the American Heart Association, 2024

Temporal biomarker concentration patterns during the early course of acute coronary syndrome

Eggers, Kai M.; Batra, Gorav; Lindahl, Bertil; Lakic, Tatevik et al.

Part of Clinical Chemistry and Laboratory Medicine, p. 1167-1176, 2024

Biomarker Concentrations and Their Temporal Changes in Patients With Myocardial Infarction and Nonobstructive Compared With Obstructive Coronary Arteries: Results From the PLATO Trial

Hjort, Marcus; Eggers, Kai M.; Ghukasyan Lakic, Tatevik; Lindbäck, Johan et al.

Part of Journal of the American Heart Association, 2023

Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets

Zhao, Jing Hua; Stacey, David; Eriksson, Niclas; Macdonald-Dunlop, Erin et al.

Part of Nature Immunology, p. 1540-1551, 2023

Development and validation of a quantitative Proximity Extension Assay instrument with 21 proteins associated with cardiovascular risk (CVD-21)

Siegbahn, Agneta; Eriksson, Niclas; Assarsson, Erika; Lundberg, Martin et al.

Part of PLOS ONE, 2023

Plasma angiopoietin-2 and its association with heart failure in patients with atrial fibrillation

Benz, Alexander P.; Hijazi, Ziad; Lindbäck, Johan; Connolly, Stuart J. et al.

Part of Europace, 2023

Vascular endothelial growth factor-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease

Davidsson, Pia; Eketjall, Susanna; Eriksson, Niclas; Walentinsson, Anna et al.

Part of Cardiovascular Research, p. 1596-1605, 2023

DOI for Vascular endothelial growth factor-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease

Individual net clinical outcome with oral anticoagulation in atrial fibrillation using the ABC-AF risk scores

Hijazi, Ziad; Lindbäck, Johan; Oldgren, Jonas; Benz, Alexander P. et al.

Part of American Heart Journal, p. 55-63, 2023

Screening for Biomarkers Associated with Left Ventricular Function During Follow-up After Acute Coronary Syndrome

Christersson, Christina; Baron, Tomasz; Flachskampf, Frank; Lindhagen, Lars et al.

Part of Journal of Cardiovascular Translational Research, p. 244-254, 2023

Genetic determinants of apixaban plasma levels and their relationship to bleeding and thromboembolic events

Attelind, Sofia; Hallberg, Pär; Wadelius, Mia; Hamberg, Anna-Karin et al.

Part of Frontiers in Genetics, 2022

Plasma-derived extracellular vesicles from myocardial infarction patients inhibits tumor necrosis factor-alpha induced cardiac cell death

Khandagale, Avinash; Lindahl, Bertil; Bergström Lind, Sara; Shevchenko, Ganna et al.

Part of Current research in translational medicine, 2022

Bone morphogenetic protein 10: a novel risk marker of ischaemic stroke in patients with atrial fibrillation

Hijazi, Ziad; Benz, Alexander P.; Lindbäck, Johan; Alexander, John H. et al.

Part of European Heart Journal, p. 208-218, 2022

Biomarkers and heart failure events in patients with atrial fibrillation in the ARISTOTLE trial evaluated by a multi-state model

Aulin, Julia; Hijazi, Ziad; Lindbäck, Johan; Alexander, John H. et al.

Part of American Heart Journal, p. 13-24, 2022

Effects of early myocardial reperfusion and perfusion on myocardial necrosis/dysfunction and inflammation in patients with ST-segment and non-ST-segment elevation acute coronary syndrome: results from the PLATelet inhibition and patients Outcomes (PLATO) trial

Batra, Gorav; Renlund, Henrik; Kunadian, Vijay; James, Stefan K. et al.

Part of European Heart Journal, p. 336-349, 2022

Multiplex protein screening of biomarkers associated with major bleeding in patients with atrial fibrillation treated with oral anticoagulation: Response to Luo and Bu

Siegbahn, Agneta

Part of Journal of Thrombosis and Haemostasis, p. 537-537, 2022

DOI for Multiplex protein screening of biomarkers associated with major bleeding in patients with atrial fibrillation treated with oral anticoagulation: Response to Luo and Bu

Genetic Landscape of the ACE2 Coronavirus Receptor

Yang, Zhijian; Macdonald-Dunlop, Erin; Chen, Jiantao; Zhai, Ranran et al.

Part of Circulation, p. 1398-1411, 2022

Biomarker-Based Prediction of Recurrent Ischemic Events in Patients With Acute Coronary Syndromes

Batra, Gorav; Lindbäck, Johan; Becker, Richard C.; Harrington, Robert A. et al.

Part of Journal of the American College of Cardiology, p. 1735-1747, 2022

DOI for Biomarker-Based Prediction of Recurrent Ischemic Events in Patients With Acute Coronary Syndromes

MircoRNA in Extracellular Vesicles from Patients with Pulmonary Arterial Hypertension Alters Endothelial Angiogenic Response

Khandagale, Avinash; Corcoran, Pádraic; Nikpour, Maryam; Isaksson, Anders et al.

Part of International Journal of Molecular Sciences, 2022

Differential effect of clopidogrel and ticagrelor on leukocyte count in relation to patient characteristics, biomarkers and genotype: a PLATO substudy.

Nelson, Thomas A; Parker, William A E; Ghukasyan, Tatevik; Westerbergh, Johan et al.

Part of Platelets, p. 425-431, 2022

Factor V Leiden Does Not Modify the Phenotype of Acute Coronary Syndrome or the Extent of Myocardial Necrosis

Mahmoodi, Bakhtawar K.; Eriksson, Niclas; Vos, Gerrit J. A.; Meijer, Karina et al.

Part of Journal of the American Heart Association, 2021

Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

Klaric, Lucija; Gisby, Jack S; Papadaki, Artemis; Muckian, Marisa D et al.

Part of medRxiv : the preprint server for health sciences, p. 1-28, 2021

Risk markers of incident atrial fibrillation in patients with coronary heart disease

Tomasdottir, Maria; Held, Claes; Hadziosmanovic, Nermin; Westerbergh, Johan et al.

Part of American Heart Journal, p. 92-101, 2021

Evaluation of the prognostic value of GDF-15, ABC-AF-bleeding score and ABC-AF-death score in patients with atrial fibrillation across different geographical areas

Pol, Tymon; Hijazi, Ziad; Lindbäck, Johan; Alexander, John H. et al.

Part of Open heart, 2021

Biomarker-Based Risk Prediction With the ABC-AF Scores in Patients With Atrial Fibrillation Not Receiving Oral Anticoagulation

Benz, Alexander P.; Hijazi, Ziad; Lindbäck, Johan; Connolly, Stuart J. et al.

Part of Circulation, p. 1863-1873, 2021

DOI for Biomarker-Based Risk Prediction With the ABC-AF Scores in Patients With Atrial Fibrillation Not Receiving Oral Anticoagulation

Factor V Leiden and the Risk of Bleeding in Patients With Acute Coronary Syndromes Treated With Antiplatelet Therapy: Pooled Analysis of 3 Randomized Clinical Trials

Mahmoodi, Bakhtawar K.; Eriksson, Niclas; Ross, Stephanie; Claassens, Daniel M. F. et al.

Part of Journal of the American Heart Association, 2021

Using multimarker screening to identify biomarkers associated with cardiovascular death in patients with atrial fibrillation.

Pol, Tymon; Hijazi, Ziad; Lindbäck, Johan; Oldgren, Jonas et al.

Part of Cardiovascular Research, p. 2112-2123, 2021

Multiplex protein screening of biomarkers associated with major bleeding in patients with atrial fibrillation treated with oral anticoagulation.

Siegbahn, Agneta; Lindbäck, Johan; Hijazi, Ziad; Åberg, Mikael et al.

Part of Journal of Thrombosis and Haemostasis, p. 2726-2737, 2021

Interleukin 6 and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Chronic Coronary Syndrome

Batra, Gorav; Ghukasyan, Tatevik; Lindbäck, Johan; Held, Claes et al.

Part of JAMA cardiology, p. 1440-1445, 2021

DOI for Interleukin 6 and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Chronic Coronary Syndrome

Screening of biomarkers for prediction of multisite artery disease in patients with recent myocardial infarction

Jönelid, Birgitta; Christersson, Christina; Hedberg, Pär; Leppert, Jerzy et al.

Part of Scandinavian Journal of Clinical and Laboratory Investigation, p. 353-360, 2021

Plasma proteins associated with cardiovascular death in patients with chronic coronary heart disease: A retrospective study

Wallentin, Lars; Eriksson, Niclas; Olszowka, Maciej; Grammer, Tanja et al.

Part of PLoS Medicine, 2021

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Folkersen, Lasse; Gustafsson, Stefan; Wang, Qin; Hvidberg Hansen, Daniel et al.

Part of Nature Metabolism, p. 1135-1148, 2020

DOI for Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial

Ueland, Thor; Åkerblom, Axel; Ghukasyan, Tatevik; Michelsen, Annika E et al.

Part of Atherosclerosis, p. 35-41, 2020

DOI for ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial

Pentraxin-3 vs C-reactive protein and other prognostic biomarkers in acute coronary syndrome: A substudy of the Platelet Inhibition and Patients Outcomes (PLATO) trial

Kontny, Frederic; Andersen, Thomas; Ueland, Thor; Åkerblom, Axel et al.

Part of European Heart Journal, p. 313-322, 2020

DOI for Pentraxin-3 vs C-reactive protein and other prognostic biomarkers in acute coronary syndrome: A substudy of the Platelet Inhibition and Patients Outcomes (PLATO) trial

Role of Extracellular Vesicles in Pulmonary Arterial Hypertension Modulation of Pulmonary Endothelial Function and Angiogenesis

Khandagale, Avinash; Åberg, Mikael; Wikström, Gerhard; Lind, Sara et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2293-2309, 2020

DOI for Role of Extracellular Vesicles in Pulmonary Arterial Hypertension Modulation of Pulmonary Endothelial Function and Angiogenesis

Prediction of Residual Risk by Ceramide-Phospholipid Score in Patients With Stable Coronary Heart Disease on Optimal Medical Therapy

Hilvo, Mika; Wallentin, Lars; Ghukasyan, Tatevik; Held, Claes et al.

Part of Journal of the American Heart Association, 2020

Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation.

Wallentin, Lars; Lindbäck, Johan; Eriksson, Niclas; Hijazi, Ziad et al.

Part of European Heart Journal, p. 4037-4046, 2020

DOI for Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation.

Serial measurement of interleukin-6 and risk of mortality in anticoagulated patients with atrial fibrillation: Insights from ARISTOTLE and RE-LY trials.

Aulin, Julia; Hijazi, Ziad; Siegbahn, Agneta; Andersson, Ulrika et al.

Part of Journal of Thrombosis and Haemostasis, p. 2287-2295, 2020

Screening of Multiple Biomarkers Associated With Ischemic Stroke in Atrial Fibrillation

Hijazi, Ziad; Wallentin, Lars; Lindbäck, Johan; Alexander, John H. et al.

Part of Journal of the American Heart Association, 2020

Association of Different Estimates of Renal Function With Cardiovascular Mortality and Bleeding in Atrial Fibrillation

Hijazi, Ziad; Granger, Christopher B.; Hohnloser, Stefan H.; Westerbergh, Johan et al.

Part of Journal of the American Heart Association, 2020

DOI for Association of Different Estimates of Renal Function With Cardiovascular Mortality and Bleeding in Atrial Fibrillation

Evaluation of the Age, Biomarkers, and Clinical History-Bleeding Risk Score in Patients With Atrial Fibrillation With Combined Aspirin and Anticoagulation Therapy Enrolled in the ARISTOTLE and RE-LY Trials

Hijazi, Ziad; Oldgren, Jonas; Lindbäck, Johan; Alexander, John H. et al.

Part of JAMA Network Open, 2020

DOI for Evaluation of the Age, Biomarkers, and Clinical History-Bleeding Risk Score in Patients With Atrial Fibrillation With Combined Aspirin and Anticoagulation Therapy Enrolled in the ARISTOTLE and RE-LY Trials

A Multi-Cohort Metabolomics Analysis Discloses Sphingomyelin (32:1) Levels to be Inversely Related to Incident Ischemic Stroke

Lind, Lars; Salihovic, Samira; Ganna, Andrea; Sundström, Johan et al.

Part of Journal of Stroke & Cerebrovascular Diseases, 2020

DOI for A Multi-Cohort Metabolomics Analysis Discloses Sphingomyelin (32:1) Levels to be Inversely Related to Incident Ischemic Stroke

Impaired Fibrinolysis Predicts Adverse Outcome in Acute Coronary Syndrome Patients with Diabetes: A PLATO Sub-Study

Sumaya, Wael; Wallentin, Lars; James, Stefan; Siegbahn, Agneta et al.

Part of Thrombosis and Haemostasis, p. 412-422, 2020

Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial

Gregersen, Ida; Michelsen, Annika E.; Lunde, Ngoc Nguyen; Åkerblom, Axel et al.

Part of Journal of the American Heart Association, 2020

DOI for Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial

Cardiac troponin is associated with cardiac outcomes in men and women with atrial fibrillation, insights from the ARISTOTLE trial

Rosjo, H.; Hijazi, Ziad; Omland, T.; Westerbergh, Johan et al.

Part of Journal of Internal Medicine, p. 248-259, 2020

Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis

d'Alessandro, Elisa; Becker, Christian; Bergmeier, Wolfgang; Bode, Christoph et al.

Part of Thrombosis and Haemostasis, p. 538-564, 2020

DOI for Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis

Clinical and Pharmacological Effects of Apixaban Dose Adjustment in the ARISTOTLE Trial

Zeitouni, Michel; Giczewska, Anna; Lopes, Renato D.; Wojdyla, Daniel M. et al.

Part of Journal of the American College of Cardiology, p. 1145-1155, 2020

DOI for Clinical and Pharmacological Effects of Apixaban Dose Adjustment in the ARISTOTLE Trial

Extracellular vesicles in atrial fibrillation and stroke

Thulin, Åsa; Lindbäck, Johan; Granger, Christopher B.; Wallentin, Lars et al.

Part of Thrombosis Research, p. 180-189, 2020

Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Zhang, Yanyu; Cedervall, Jessica; Hamidi, Anahita; Herre, Melanie et al.

Part of Cancer Research, p. 3345-3358, 2020

DOI for Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Activation of β1 integrins and caveolin-1 by TF/FVIIa promotes IGF-1R signaling and cell survival

Åberg, Mikael; Edén, Desireé; Siegbahn, Agneta

Part of Apoptosis (London), p. 519-534, 2020

C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes

Andersen, Thomas; Ueland, Thor; Ghukasyan Lakic, Tatevik; Åkerblom, Axel et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2402-2410, 2019

DOI for C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes

Tissue factor in ulcerative colitis, with and without concomitant primary sclerosing cholangitis.

Vessby, Johan; Lampinen, Maria; Åberg, Mikael; Rorsman, Fredrik et al.

Part of Upsala Journal of Medical Sciences, p. 238-245, 2019

DOI for Tissue factor in ulcerative colitis, with and without concomitant primary sclerosing cholangitis.

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events: A GENIUS-CHD Study of Individual Participant Data

Patel, Riyaz S.; Schmidt, Amand F.; Tragante, Vinicius; McCubrey, Raymond O. et al.

Part of Circulation, 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease: Design and Rationale of the GENIUS-CHD Consortium

Patel, Riyaz S.; Tragante, Vinicius; Schmidt, Amand F.; McCubrey, Raymond O. et al.

Part of Circulation, 2019

Adipocytes express tissue factor and FVII and are procoagulant in a TF/FVIIa-dependent manner

Edén, Desireé; Panagiotou, Grigorios; Mokhtari, Dariush; Eriksson, Jan et al.

Part of Upsala Journal of Medical Sciences, p. 158-167, 2019

Prevalence and relevance of abnormal glucose metabolism in acute coronary syndromes: insights from the PLATelet inhibition and patient Outcomes (PLATO) trial

Åkerblom, Axel; Wojdyla, Daniel; Steg, Philippe Gabriel; Wallentin, Lars et al.

Part of Journal of Thrombosis and Thrombolysis, p. 563-569, 2019

Effect of apixaban compared with warfarin on coagulation markers in atrial fibrillation.

Christersson, Christina; Wallentin, Lars; Andersson, Ulrika; Alexander, John H et al.

Part of Heart, p. 235-242, 2019

Admission Levels of DKK1 (Dickkopf-1) Are Associated With Future Cardiovascular Death in Patients With Acute Coronary Syndromes

Ueland, Thor; Åkerblom, Axel; Ghukasyan, Tatevik; Michelsen, Annika E et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 294-302, 2019

DOI for Admission Levels of DKK1 (Dickkopf-1) Are Associated With Future Cardiovascular Death in Patients With Acute Coronary Syndromes

Prognostic impact of baseline inflammatory markers in patients with acute coronary syndromes treated with ticagrelor and clopidogrel.

Thomas, Mark R.; James, Stefan; Becker, Richard C.; Himmelmann, Anders et al.

Part of European Heart Journal, p. 153-163, 2019

DOI for Prognostic impact of baseline inflammatory markers in patients with acute coronary syndromes treated with ticagrelor and clopidogrel.

Interleukin-18 in patients with acute coronary syndromes.

Åkerblom, Axel; James, Stefan K.; Lakic, Tatevik G; Becker, Richard C et al.

Part of Clinical Cardiology, p. 1202-1209, 2019

DOI for Interleukin-18 in patients with acute coronary syndromes.

Sensitive and Specific Detection of Platelet-Derived and Tissue Factor-Positive Extracellular Vesicles in Plasma using Solid-Phase Proximity Ligation Assay

Thulin, Åsa; Yan, Junhong; Åberg, Mikael; Christersson, Christina et al.

Part of Thrombosis and Haemostasis open, 2018

DOI for Sensitive and Specific Detection of Platelet-Derived and Tissue Factor-Positive Extracellular Vesicles in Plasma using Solid-Phase Proximity Ligation Assay

Sensitive detection of platelet-derived and tissue factor positive extracellular vesicles in plasma using solid-phase proximity ligation assay

Thulin, Åsa; Yan, J.; Åberg, Mikael; Christersson, Christina et al.

Part of Cardiovascular Research, 2018

Obesity paradox on outcome in atrial fibrillation maintained even considering the prognostic influence of biomarkers: insights from the ARISTOTLE trial

Sandhu, Roopinder K.; Ezekowitz, Justin A.; Hijazi, Ziad; Westerbergh, Johan et al.

Part of Open heart, 2018

Methylation-based estimated biological age and cardiovascular disease

Lind, Lars; Ingelsson, Erik; Sundström, Johan; Siegbahn, Agneta et al.

Part of European Journal of Clinical Investigation, 2018

DOI for Methylation-based estimated biological age and cardiovascular disease

Osteoprotegerin Is Associated With Major Bleeding But Not With Cardiovascular Outcomes in Patients With Acute Coronary Syndromes: Insights From the PLATO (Platelet Inhibition and Patient Outcomes) Trial

Ueland, Thor; Åkerblom, Axel; Ghukasyan, Tatevik; Michelsen, Annika E. et al.

Part of Journal of the American Heart Association, 2018

Novel Prognostic Biomarkers For Ischemic Stroke In Patients With Atrial Fibrillation Using Multimarker Screening: Insights From The Aristotle Trial

Hijazi, Ziad; Pol, Tymon; Oldgren, Jonas; Lindbäck, Johan et al.

Part of Journal of the American College of Cardiology, p. 506-506, 2018

Proteomic, functional and receptor studies of growth differentiation factor 15, GDF-15

Kask, Lena; Hörnaeus, Katarina; Åberg, Mikael; Jorsback, A. et al.

Part of Cardiovascular Research, 2018

New Biomarkers Associated With Cardiovascular Death In Patients With Atrial Fibrillation Using Multimarker Screening: Insights From The Aristotle Trial

Pol, Tymon; Hijazi, Ziad; Lindbäck, Johan; Oldgren, Jonas et al.

Part of Journal of the American College of Cardiology, p. 330-330, 2018

DOI for New Biomarkers Associated With Cardiovascular Death In Patients With Atrial Fibrillation Using Multimarker Screening: Insights From The Aristotle Trial

Fibrin clot properties independently predict adverse clinical outcome following acute coronary syndrome: a PLATO substudy

Sumaya, Wael; Wallentin, Lars; James, Stefan K.; Siegbahn, Agneta et al.

Part of European Heart Journal, p. 1078-1085, 2018

Antithrombotic therapy and body mass: an expert position paper of the ESC Working Group on Thrombosis

Rocca, Bianca; Fox, Keith A. A.; Ajjan, Ramzi A.; Andreotti, Felicita et al.

Part of European Heart Journal, p. 1672-1686, 2018

DOI for Antithrombotic therapy and body mass: an expert position paper of the ESC Working Group on Thrombosis

A biomarker-based risk score to predict death in patients with atrial fibrillation: the ABC (age, biomarkers, clinical history) death risk score

Hijazi, Ziad; Oldgren, Jonas; Lindbäck, Johan; Alexander, John H. et al.

Part of European Heart Journal, p. 477-485, 2018

Activation of beta1-integrins and caveolin-1 by TF/FVIIa promotes cell survival

Åberg, Mikael; Edén, Desireé; Siegbahn, Agneta

Part of Cardiovascular Research, 2018

Adipocytes are coagulant active in a TF/FVIIa dependent manner but lipolysis is unaffected by TF/FVIIa

Edén, Desireé; Mokhtari, Dariush; Eriksson, Jan W; Åberg, Mikael et al.

Part of Cardiovascular Research, 2018

Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement

Ljungberg, Johan; Janiec, Mikael; Bergdahl, Ingvar A.; Holmgren, Anders et al.

Part of Circulation, p. 590-599, 2018

Use of Biomarkers to Predict Specific Causes of Death in Patients With Atrial Fibrillation: Insights From the ARISTOTLE Trial

Sharma, Abhinav; Hijazi, Ziad; Andersson, Ulrika; Al-Khatib, Sana M. et al.

Part of Circulation, p. 1666-1676, 2018

DOI for Use of Biomarkers to Predict Specific Causes of Death in Patients With Atrial Fibrillation: Insights From the ARISTOTLE Trial

Association of Multiple Biomarkers With Risk of All-Cause and Cause-Specific Mortality After Acute Coronary Syndromes: A Secondary Analysis of the PLATO Biomarker Study

Lindholm, Daniel P; James, Stefan K; Gabrysch, Katja; Storey, Robert F et al.

Part of JAMA cardiology, p. 1160-1166, 2018

DOI for Association of Multiple Biomarkers With Risk of All-Cause and Cause-Specific Mortality After Acute Coronary Syndromes: A Secondary Analysis of the PLATO Biomarker Study

Carotid Endarterectomy Induces the Release of Inflammatory Markers and the Activation of Coagulation as Measured in the Jugular Bulb

Kragsterman, Björn; Bergqvist, David; Siegbahn, Agneta; Pärsson, Håkan

Part of Journal of Stroke & Cerebrovascular Diseases, p. 2320-2328, 2017

DOI for Carotid Endarterectomy Induces the Release of Inflammatory Markers and the Activation of Coagulation as Measured in the Jugular Bulb

Lowenstern, Angela; Storey, Robert F.; Neely, Megan; Sun, Jie-Lena et al.

Part of Journal of Thrombosis and Thrombolysis, p. 145-153, 2017

DOI for Platelet-related biomarkers and their response to inhibition with aspirin and p2y₁₂-receptor antagonists in patients with acute coronary syndrome

IL-33 stimulates the release of procoagulant microvesicles from human monocytes and differentially increases tissue factor in human monocyte subsets

Stojkovic, Stefan; Thulin, Åsa; Hell, Lena; Thaler, Barbara et al.

Part of Thrombosis and Haemostasis, p. 1379-1390, 2017

DOI for IL-33 stimulates the release of procoagulant microvesicles from human monocytes and differentially increases tissue factor in human monocyte subsets

Repeated Measurements of Cardiac Biomarkers in Atrial Fibrillation and Validation of the ABC Stroke Score Over Time

Hijazi, Ziad; Lindahl, Bertil; Oldgren, Jonas; Andersson, Ulrika et al.

Part of Journal of the American Heart Association, 2017

DOI for Repeated Measurements of Cardiac Biomarkers in Atrial Fibrillation and Validation of the ABC Stroke Score Over Time

Biomarker-Based Risk Model to Predict Cardiovascular Mortality in Patients With Stable Coronary Disease

Lindholm, Daniel; Lindbäck, Johan; Armstrong, Paul W.; Budaj, Andrzej et al.

Part of Journal of the American College of Cardiology, p. 813-826, 2017

DOI for Biomarker-Based Risk Model to Predict Cardiovascular Mortality in Patients With Stable Coronary Disease

Impact of physical activity on cardiovascular status in obesity

Lind, Lars; Carlsson, Axel C.; Siegbahn, Agneta; Sundström, Johan et al.

Part of European Journal of Clinical Investigation, p. 167-175, 2017

DOI for Impact of physical activity on cardiovascular status in obesity

Growth Differentiation Factor 15 Predicts All-Cause Morbidity and Mortality in Stable Coronary Heart Disease

Hagström, Emil; Held, Claes; Stewart, Ralph A H; Aylward, Philip E et al.

Part of Clinical Chemistry, p. 325-333, 2017

DOI for Growth Differentiation Factor 15 Predicts All-Cause Morbidity and Mortality in Stable Coronary Heart Disease

Outcomes after planned invasive or conservative treatment strategy in patients with non-ST-elevation acute coronary syndrome and a normal value of high sensitivity troponin at randomisation: A Platelet Inhibition and Patient Outcomes (PLATO) trial biomarker substudy.

Giannitsis, Evangelos; Wallentin, Lars; James, Stefan K; Bertilsson, Maria et al.

Part of European Heart Journal, p. 500-510, 2017

DOI for Outcomes after planned invasive or conservative treatment strategy in patients with non-ST-elevation acute coronary syndrome and a normal value of high sensitivity troponin at randomisation: A Platelet Inhibition and Patient Outcomes (PLATO) trial biomarker substudy.

Growth Differentiation Factor 15 at 1 Month After an Acute Coronary Syndrome Is Associated With Increased Risk of Major Bleeding.

Lindholm, Daniel P; Hagström, Emil; James, Stefan K; Becker, Richard C et al.

Part of Journal of the American Heart Association, 2017

Associations between tooth loss and prognostic biomarkers and the risk for cardiovascular events in patients with stable coronary heart disease

Vedin, Ola; Hagström, Emil; Östlund, Ollie; Avezum, Alvaro et al.

Part of International Journal of Cardiology, p. 271-276, 2017

DOI for Associations between tooth loss and prognostic biomarkers and the risk for cardiovascular events in patients with stable coronary heart disease

Inflammatory Biomarkers Interleukin-6 and C-Reactive Protein and Outcomes in Stable Coronary Heart Disease: Experiences From the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial

Held, Claes; White, Harvey D.; Stewart, Ralph A. H.; Budaj, Andrzej et al.

Part of Journal of the American Heart Association, 2017

DOI for Inflammatory Biomarkers Interleukin-6 and C-Reactive Protein and Outcomes in Stable Coronary Heart Disease: Experiences From the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial

GDF-15 and TRAIL-R2 are powerful predictors of long-term mortality in patients with acute myocardial infarction

Skau, Emma; Henriksen, Egil; Wagner, Philippe; Hedberg, Pär et al.

Part of European Journal of Preventive Cardiology, p. 1576-1583, 2017

DOI for GDF-15 and TRAIL-R2 are powerful predictors of long-term mortality in patients with acute myocardial infarction

The utility of coagulation activity for prediction of risk of mortality and cardiovascular events in guideline-treated myocardial infarction patients

Christersson, Christina; Lindahl, Bertil; Berglund, Lars; Siegbahn, Agneta et al.

Part of Upsala Journal of Medical Sciences, p. 224-233, 2017

Biomarkers and Coronary Lesions Predict Outcomes after Revascularization in Non-ST-Elevation Acute Coronary Syndrome

Lindholm, Daniel P; James, Stefan K; Bertilsson, Maria; Becker, Richard C et al.

Part of Clinical Chemistry, p. 573-584, 2017

DOI for Biomarkers and Coronary Lesions Predict Outcomes after Revascularization in Non-ST-Elevation Acute Coronary Syndrome

Growth-differentiation factor 15 and risk of major bleeding in atrial fibrillation: Insights from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial

Hijazi, Ziad; Oldgren, Jonas; Andersson, Ulrika; Connolly, Stuart J et al.

Part of American Heart Journal, p. 94-103, 2017

DOI for Growth-differentiation factor 15 and risk of major bleeding in atrial fibrillation: Insights from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial

How to use D-dimer in acute cardiovascular care

Giannitsis, Evangelos; Mair, Johannes; Christersson, Christina; Siegbahn, Agneta et al.

Part of European Heart Journal, p. 69-80, 2017

DOI for How to use D-dimer in acute cardiovascular care

Microparticles during long-term follow-up after acute myocardial infarction: Association to atherosclerotic burden and risk of cardiovascular events

Christersson, Christina; Thulin, Åsa; Siegbahn, Agneta

Part of Thrombosis and Haemostasis, p. 1571-1581, 2017

DOI for Microparticles during long-term follow-up after acute myocardial infarction: Association to atherosclerotic burden and risk of cardiovascular events

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

Zewinger, Stephen; Kleber, Marcus E.; Tragante, Vinicius; McCubrey, Raymond O. et al.

Part of The Lancet Diabetes and Endocrinology, p. 534-543, 2017

DOI for Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

Role and analysis of monocyte subsets in cardiovascular disease Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis"

Weber, Christian; Shantsila, Eduard; Hristov, Michael; Caligiuri, Giuseppina et al.

Part of Thrombosis and Haemostasis, p. 626-637, 2016

DOI for Role and analysis of monocyte subsets in cardiovascular disease Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis"

The ABC risk score for patients with atrial fibrillation Reply

Hijazi, Ziad; Oldgren, Jonas; Lindbäck, Johan; Siegbahn, Agneta et al.

Part of The Lancet, p. 1980-1981, 2016

Lipoprotein-Associated Phospholipase A(2) Activity Is a Marker of Risk But Not a Useful Target for Treatment in Patients With Stable Coronary Heart Disease

Wallentin, Lars; Held, Claes; Armstrong, Paul W.; Cannon, Christopher P. et al.

Part of Journal of the American Heart Association, 2016

DOI for Lipoprotein-Associated Phospholipase A(2) Activity Is a Marker of Risk But Not a Useful Target for Treatment in Patients With Stable Coronary Heart Disease

Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome

Johansson, Åsa; Eriksson, Niclas; Lindholm, Daniel; Varenhorst, Christoph et al.

Part of Human Molecular Genetics, p. 1447-1456, 2016

DOI for Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome

A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression

Eriksson, Oskar; Asplund, Anna; Hegde, Geeta; Edqvist, Per-Henrik D et al.

Part of Thrombosis and Haemostasis, p. 1050-1059, 2016

DOI for A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression

The composition and daily variation of microparticles in whole blood in stable coronary artery disease

Christersson, Christina; Lindahl, Bertil; Siegbahn, Agneta

Part of Scandinavian Journal of Clinical and Laboratory Investigation, 2016

DOI for The composition and daily variation of microparticles in whole blood in stable coronary artery disease

External Validation Of The Biomarker-Based ABC-Stroke Risk Score For Atrial Fibrillation

Oldgren, Jonas; Hijazi, Ziad; Lindbäck, Johan; Alexander, John et al.

Part of Journal of the American College of Cardiology, p. 879-879, 2016

Prediction Of Major Bleeding In Revascularized Patients With Acute Coronary Syndromes: Development Of A Novel Biomarker-Based Clinical Prediction Model

Lindholm, Daniel; Lindbäck, Johan; James, Stefan; Becker, Richard et al.

Part of Journal of the American College of Cardiology, p. 493-493, 2016

Oral anticoagulants in coronary heart disease (Section IV) Position paper of the ESC Working Group on Thrombosis - Task Force on Anticoagulants in Heart Disease

De Caterina, Raffaele; Husted, Steen; Wallentin, Lars; Andreotti, Felicita et al.

Part of Thrombosis and Haemostasis, p. 685-711, 2016

DOI for Oral anticoagulants in coronary heart disease (Section IV) Position paper of the ESC Working Group on Thrombosis - Task Force on Anticoagulants in Heart Disease

Dabigatran etexilate and reduction in serum apolipoprotein B

Joseph, Philip; Pare, Guillaume; Wallentin, Lars; Connolly, Stuart et al.

Part of Heart, p. 57-62, 2016

DOI for Dabigatran etexilate and reduction in serum apolipoprotein B

D-dimer and factor VIIa in atrial fibrillation: prognostic values for cardiovascular events and effects of anticoagulation therapy. A RE-LY substudy

Siegbahn, Agneta; Oldgren, Jonas; Andersson, Ulrika; Ezekowitz, Michael D et al.

Part of Thrombosis and Haemostasis, p. 921-930, 2016

DOI for D-dimer and factor VIIa in atrial fibrillation: prognostic values for cardiovascular events and effects of anticoagulation therapy. A RE-LY substudy

Decreased levels of stem cell factor in subjects with incident coronary events

Wigren, M; Rattik, S; Hultman, K; Björkbacka, H et al.

Part of Journal of Internal Medicine, p. 180-191, 2016

DOI for Decreased levels of stem cell factor in subjects with incident coronary events

Performance and Validation of a Novel Biomarker-Based Stroke Risk Score for Atrial Fibrillation

Oldgren, Jonas; Hijazi, Ziad; Lindbäck, Johan; Alexander, John H et al.

Part of Circulation, p. 1697-1707, 2016

DOI for Performance and Validation of a Novel Biomarker-Based Stroke Risk Score for Atrial Fibrillation

Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation

Hijazi, Ziad; Aulin, Julia; Andersson, Ulrika; Alexander, John H. et al.

Part of Heart, p. 508-517, 2016

DOI for Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation

External Validation Of The Biomarker-Based ABC-Bleeding Risk Score For Atrial Fibrillation

Hijazi, Ziad; Oldgren, Jonas; Lindbäck, Johan; Alexander, John et al.

Part of Journal of the American College of Cardiology, p. 893-893, 2016

The Relationship Between Tooth Loss, Cardiovascular Biomarkers And Outcomes In Patients With Stable Coronary Heart Disease

Vedin, Ola; Hagström, Emil; Östlund, Ollie; Avezum, Alvaro et al.

Part of Journal of the American College of Cardiology, p. 1969-1969, 2016

Tissue factor/FVIIa transactivates the IGF-1R by a Src-dependent phosphorylation of caveolin-1

Åberg, Mikael; Siegbahn, Agneta

Part of Cardiovascular Research, 2016

Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation in Relation to Renal Function Over Time: Insights From the ARISTOTLE Randomized Clinical Trial

Hijazi, Ziad; Hohnloser, Stefan H; Andersson, Ulrika; Alexander, John H et al.

Part of JAMA cardiology, p. 451-460, 2016

DOI for Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation in Relation to Renal Function Over Time: Insights From the ARISTOTLE Randomized Clinical Trial

Growth differentiation factor-15 level predicts major bleeding and cardiovascular events in patients with acute coronary syndromes: results from the PLATO study

Hagström, Emil; James, Stefan; Bertilsson, Maria; Becker, Richard C et al.

Part of European Heart Journal, p. 1325-1333, 2016

DOI for Growth differentiation factor-15 level predicts major bleeding and cardiovascular events in patients with acute coronary syndromes: results from the PLATO study

Cross-talk between the Tissue Factor/coagulation factor VIIa complex and the tyrosine kinase receptor EphA2 in cancer

Eriksson, Oskar; Thulin, Åsa; Asplund, Anna; Hegde, Geeta et al.

Part of BMC Cancer, 2016

Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy

Eriksson, Niclas; Wallentin, Lars; Berglund, Lars; Axelsson, Tomas et al.

Part of Pharmacogenomics (London), p. 1425-1439, 2016

The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation

Hijazi, Ziad; Lindbäck, Johan; Alexander, John H.; Hanna, Michael et al.

Part of European Heart Journal, p. 1582-1590, 2016

DOI for The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation

The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study

Hijazi, Ziad; Oldgren, Jonas; Lindbäck, Johan; Alexander, John H. et al.

Part of The Lancet, p. 2302-2311, 2016

DOI for The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study

MiR-223-3p post-transcriptionally regulates the expression of F3, the human tissue factor gene, and TF expression in acute coronary syndrome

Siegbahn, Agneta; Christersson, Christina; Alfredsson, Jenny

Part of European Heart Journal, p. 335-335, 2015

Genetically Determined Height and Coronary Artery Disease

Nelson, C. P.; Hamby, S. E.; Saleheen, D.; Hopewell, J. C. et al.

Part of New England Journal of Medicine, p. 1608-1618, 2015

DOI for Genetically Determined Height and Coronary Artery Disease

Biomarkers for risk stratification of patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention: Insights from the Platelet Inhibition and Patient Outcomes trial

Velders, Matthijs A.; Wallentin, Lars; Becker, Richard C.; van Boven, Adrianus J. et al.

Part of American Heart Journal, p. 879-8890000000, 2015

Cross-talk between tissue factor and EPHA2 in cancer: potentiation of ligand-dependent EPHA2-signaling in vitro and co-expression in human colorectal cancer specimens

Eriksson, Oskar; Thulin, Åsa; Asplund, Anna; Hedge, G. et al.

Part of Journal of Thrombosis and Haemostasis, p. 111-111, 2015

Tissue factor/factor VIIA signaling promotes cytokine-induced beta cell death and impairs glucose stimulated insulin secretion from human pancreatic islets

Edén, Desireé; Siegbahn, Agneta; Mokhtari, Dariush

Part of Journal of Thrombosis and Haemostasis, p. 465-465, 2015

The change of the amount of circulating microparticles and their association to the general atherosclerotic burden after acute coronary syndrome

Christersson, Christina; Jönelid, Birgitta; Thulin, Åsa; Siegbahn, Agneta

Part of Journal of Thrombosis and Haemostasis, p. 214-214, 2015

Comparison of Cardiac Troponins I and T Measured with High-Sensitivity Methods for Evaluation of Prognosis in Atrial Fibrillation: An ARISTOTLE Substudy

Hijazi, Ziad; Siegbahn, Agneta; Andersson, Ulrika; Lindahl, Bertil et al.

Part of Clinical Chemistry, p. 368-378, 2015

DOI for Comparison of Cardiac Troponins I and T Measured with High-Sensitivity Methods for Evaluation of Prognosis in Atrial Fibrillation: An ARISTOTLE Substudy

Activated Leukocyte Cell Adhesion Molecule (ALCAM) And Outcomes In Acute Coronary Syndromes: A Plato Biomarker Substudy

Wallentin, Lars; Michelsen, Annika E.; Aukrust, Pal; Becker, Richard et al.

Part of Journal of the American College of Cardiology, 2015

DOI for Activated Leukocyte Cell Adhesion Molecule (ALCAM) And Outcomes In Acute Coronary Syndromes: A Plato Biomarker Substudy

Growth Differentiation Factor-15 (GDF-15) For Prognostication Of Outcomes In Stable Coronary Artery Disease: Experiences From The Stability Trial

Wallentin, Lars; Held, Claes; Stewart, Ralph; Budaj, Andrzej et al.

Part of Journal of the American College of Cardiology, 2015

High Plasma Levels of Heparin-Binding Epidermal Growth Factor Are Associated With a More Stable Plaque Phenotype and Reduced Incidence of Coronary Events

Rattik, Sara; Wigren, Maria; Bjorkbacka, Harry; Fredrikson, Gunilla Nordin et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 222-228, 2015

DOI for High Plasma Levels of Heparin-Binding Epidermal Growth Factor Are Associated With a More Stable Plaque Phenotype and Reduced Incidence of Coronary Events

Use of a proximity extension assay proteomics chip to discover new biomarkers for human atherosclerosis

Lind, Lars; Ärnlöv, Johan; Lindahl, Bertil; Siegbahn, Agneta et al.

Part of Atherosclerosis, p. 205-210, 2015

DOI for Use of a proximity extension assay proteomics chip to discover new biomarkers for human atherosclerosis

Biomarker-based risk score for prediction of cardiovascular events in stable coronary heart disease - Experiences from the STABILITY biomarker substudy

Wallentin, Lars C.; Lindbäck, Johan; Held, Claes; Granger, C. B. et al.

Part of European Heart Journal, p. 1041-1042, 2015

External validation of the biomarker-based ABC-stroke risk score for atrial fibrillation

Hijazi, Ziad; Lindbäck, Johan; Östlund, Olof Petter; Siegbahn, Agneta et al.

Part of European Heart Journal, p. 710-711, 2015

Efficacy and safety of apixaban compared with warfarin in relation to renal function over time in patients with atrial fibrillation: Insights from the ARISTOTLE trial

Hijazi, Ziad; Hohnloser, S. H.; Andersson, Ulrika; Alexander, J. H. et al.

Part of European Heart Journal, p. 339-339, 2015

NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO)

Johansson, Åsa; Eriksson, Niclas; Becker, Richard C.; Storey, Robert F. et al.

Part of Circulation, p. 498-506, 2015

DOI for NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO)

Biomarker-based prediction model for recurrent ischemic events in revascularised patients with acute coronary syndromes

Lindholm, Daniel; Lindback, Johan; James, Stefan K.; Becker, R. C. et al.

Part of European Heart Journal, p. 10-11, 2015

Discovery of New Risk Markers for Ischemic Stroke Using a Novel Targeted Proteomics Chip

Lind, Lars; Siegbahn, Agneta; Lindahl, Bertil; Stenemo, Markus et al.

Part of Stroke, p. 3340-3347, 2015

DOI for Discovery of New Risk Markers for Ischemic Stroke Using a Novel Targeted Proteomics Chip

Associations between circulating proteins and corresponding genes expressed in coronary thrombi in patients with acute myocardial infarction

Helseth, Ragnhild; Weiss, Thomas W.; Opstad, Trine Baur; Siegbahn, Agneta et al.

Part of Thrombosis Research, p. 1240-1244, 2015

DOI for Associations between circulating proteins and corresponding genes expressed in coronary thrombi in patients with acute myocardial infarction

Effect of genetic variations on ticagrelor plasma levels and clinical outcomes

Varenhorst, Christoph; Eriksson, Niclas; Johansson, Åsa; Barratt, Bryan J. et al.

Part of European Heart Journal, p. 1901-1912, 2015

DOI for Effect of genetic variations on ticagrelor plasma levels and clinical outcomes

Genome-Wide Association Study Identifies That the ABO Blood Group System Influences Interleukin-10 Levels and the Risk of Clinical Events in Patients with Acute Coronary Syndrome

Johansson, Åsa; Alfredsson, Jenny; Eriksson, Niclas; Wallentin, Lars et al.

Part of PLOS ONE, 2015

Interleukin-6 and C-reactive protein and risk for death and cardiovascular events in patients with atrial fibrillation

Aulin, Julia; Siegbahn, Agneta; Hijazi, Ziad; Ezekowitz, Michael D. et al.

Part of American Heart Journal, p. 1151-1160, 2015

DOI for Interleukin-6 and C-reactive protein and risk for death and cardiovascular events in patients with atrial fibrillation

Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets

Edén, Desireé; Siegbahn, Agneta; Mokhtari, Dariush

Part of Diabetologia, p. 2563-2572, 2015

Tissue factor/FVIIA transactivates the IGF-1R in prostate cancer cells via inhibition of caveolin-1

Åberg, Mikael; Siegbahn, Agneta

Part of Journal of Thrombosis and Haemostasis, p. 707-707, 2015

New technique to study cell-derived microparticles

Thulin, Åsa; Yan, J.; Kamali-Moghaddam, Masood; Siegbahn, Agneta

Part of Journal of Thrombosis and Haemostasis, p. 627-627, 2015

Tissue Factor Noncoagulant Signaling: Mechanisms and Implications for Cell Migration and Apoptosis

Aberg, Mikael; Eriksson, Oskar; Siegbahn, Agneta

Part of Seminars in Thrombosis and Hemostasis, p. 691-699, 2015

DOI for Tissue Factor Noncoagulant Signaling: Mechanisms and Implications for Cell Migration and Apoptosis

Large-scale Metabolomic Profiling Identifies Novel Biomarkers for Incident Coronary Heart Disease

Ganna, Andrea; Salihovic, Samira; Sundström, Johan; Broeckling, Corey D et al.

Part of PLOS Genetics, 2014

The Eph Tyrosine Kinase Receptors EphB2 and EphA2 Are Novel Proteolytic Substrates of Tissue Factor/Coagulation Factor VIIa

Eriksson, Oskar; Ramström, Margareta; Hörnaeus, Katarina; Bergquist, Jonas et al.

Part of Journal of Biological Chemistry, 2014

DOI for The Eph Tyrosine Kinase Receptors EphB2 and EphA2 Are Novel Proteolytic Substrates of Tissue Factor/Coagulation Factor VIIa

Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet Inhibition and Patient Outcomes (PLATO) Study

Åkerblom, Axel; Eriksson, Niclas; Wallentin, Lars; Siegbahn, Agneta et al.

Part of American Heart Journal, p. 96-102, 2014

DOI for Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet Inhibition and Patient Outcomes (PLATO) Study

Secreted wingless (Wnt) antagonists and risk prediction in acute coronary syndrome (ACS) a PLATO biomarker substudy

Ueland, T.; Aukrust, P.; Michelsen, A.; Bertilsson, Maria et al.

Part of European Heart Journal, p. 318-318, 2014

Galectin-3 is associated with worse clinical outcome in patients with atrial fibrillation: A substudy from the ARISTOTLE trial

Åsberg, S.; Hijazi, Ziad; Siegbahn, Agneta; Andersson, Ulrika et al.

Part of European Heart Journal, p. 426-426, 2014

D-dimer and risk of thromboembolic and bleeding events in patients with atrial fibrillation: observations from the ARISTOTLE trial

Christersson, Christina; Wallentin, Lars; Andersson, Ulrika; Alexander, J. H. et al.

Part of Journal of Thrombosis and Haemostasis, p. 1401-1412, 2014

DOI for D-dimer and risk of thromboembolic and bleeding events in patients with atrial fibrillation: observations from the ARISTOTLE trial

High Sensitivity Troponin T and Risk Stratification in Patients with Atrial Fibrillation during Treatment with Apixaban or Warfarin

Hijazi, Ziad; Wallentin, Lars; Siegbahn, Agneta; Andersson, Ulrika et al.

Part of Journal of the American College of Cardiology, p. 52-61, 2014

DOI for High Sensitivity Troponin T and Risk Stratification in Patients with Atrial Fibrillation during Treatment with Apixaban or Warfarin

Importance of Persistent Elevation of Cardiac Biomarkers in Atrial Fibrillation: a RE-LY Substudy

Hijazi, Ziad; Oldgren, Jonas; Andersson, Ulrika; Connolly, Stuart J. et al.

Part of Heart, p. 1193-1200, 2014

DOI for Importance of Persistent Elevation of Cardiac Biomarkers in Atrial Fibrillation: a RE-LY Substudy

Interleukin-6 and C-reactive protein and risk for cardiovascular events and death in anticoagulated patients with atrial fibrillation

Aulin, Julia; Hijazi, Ziad; Andersson, Ulrika; Gersh, B. J. et al.

Part of European Heart Journal, p. 1115-1116, 2014

Growth Differentiation Factor 15, a Marker of Oxidative Stress and Inflammation, for Risk Assessment in Patients With Atrial Fibrillation: Insights From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial

Wallentin, Lars; Hijazi, Ziad; Andersson, Ulrika; Alexander, John H. et al.

Part of Circulation, p. 1847-1858, 2014

DOI for Growth Differentiation Factor 15, a Marker of Oxidative Stress and Inflammation, for Risk Assessment in Patients With Atrial Fibrillation: Insights From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial

Chemokine (CXC motif) ligand 16 (CXCL16) and osteoprotegerin (OPG) as predictors of outcome in patients with acute coronary syndromes (ACS) a PLATO biomarker substudy

Ueland, T.; Michelsen, A.; Aukrust, P.; Becker, R. et al.

Part of European Heart Journal, p. 486-486, 2014

The efficacy of apixaban compared to warfarin in patients with atrial fibrillation with high coagulation activity despite anticoagulant treatment

Christersson, Christina; Wallentin, Lars; Andersson, Ulrika; Hylek, E. M. et al.

Part of European Heart Journal, p. 866-867, 2014

A new biomarker based risk score for predicting major bleeding in atrial fibrillation - the ABC (age, biomarkers, current disease) risk score

Hijazi, Ziad; Lindbäck, Johan; Siegbahn, Agneta; Alexander, J. H. et al.

Part of European Heart Journal, p. 357-357, 2014

Non-vitamin K antagonist oral anticoagulants (NOACs): No longer new or novel

Husted, Steen; de Caterina, Raffaele; Andreotti, Felicita; Arnesen, Harald et al.

Part of Thrombosis and Haemostasis, p. 781-782, 2014

DOI for Non-vitamin K antagonist oral anticoagulants (NOACs): No longer new or novel

Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study

Storey, Robert F; James, Stefan K; Siegbahn, Agneta; Varenhorst, Christoph et al.

Part of Platelets, p. 517-525, 2014

DOI for Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study

Pentraxin 3 (PTX3) predict adverse outcome in acute coronary syndromes - a PLATO biomarker substudy

Kontny, F.; Ueland, T.; Aukrust, P.; Michelsen, A. E. et al.

Part of European Heart Journal, p. 319-319, 2014

Response to Letter Regarding Article, "Efficacy and Safety of Dabigatran Compared With Warfarin in Relation to Baseline Renal Function in Patients With Atrial Fibrillation: A RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) Trial Analysis"

Hijazi, Ziad; Hohnloser, Stefan H.; Oldgren, Jonas; Andersson, Ulrika et al.

Part of Circulation, 2014

DOI for Response to Letter Regarding Article, "Efficacy and Safety of Dabigatran Compared With Warfarin in Relation to Baseline Renal Function in Patients With Atrial Fibrillation: A RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) Trial Analysis"

Efficacy and Safety of Dabigatran Compared With Warfarin in Relation to Baseline Renal Function in Patients With Atrial Fibrillation A RE-LY (Randomized Evaluation of Long-term Anticoagulation Therapy) Trial Analysis

Hijazi, Ziad; Hohnloser, Stefan H.; Oldgren, Jonas; Andersson, Ulrika et al.

Part of Circulation, p. 961-970, 2014

DOI for Efficacy and Safety of Dabigatran Compared With Warfarin in Relation to Baseline Renal Function in Patients With Atrial Fibrillation A RE-LY (Randomized Evaluation of Long-term Anticoagulation Therapy) Trial Analysis

Tissue factor/factor VIIa induces cell survival and gene transcription by transactivation of the insulin-like growth factor 1 receptor

Åberg, Mikael; Eriksson, Oskar; Mokhtari, Dariush; Siegbahn, Agneta

Part of Thrombosis and Haemostasis, p. 748-760, 2014

DOI for Tissue factor/factor VIIa induces cell survival and gene transcription by transactivation of the insulin-like growth factor 1 receptor

High-Sensitivity Troponin I for Risk Assessment in Patients With Atrial Fibrillation Insights From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial

Hijazi, Ziad; Siegbahn, Agneta; Andersson, Ulrika; Granger, Christopher B. et al.

Part of Circulation, p. 625-634, 2014

DOI for High-Sensitivity Troponin I for Risk Assessment in Patients With Atrial Fibrillation Insights From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial

Biomarkers in Relation to the Effects of Ticagrelor in Comparison With Clopidogrel in Non-ST-Elevation Acute Coronary Syndrome Patients Managed With or Without In-Hospital Revascularization A Substudy From the Prospective Randomized Platelet Inhibition and Patient Outcomes (PLATO) Trial

Wallentin, Lars; Lindholm, Daniel; Siegbahn, Agneta; Wernroth, Lisa et al.

Part of Circulation, p. 293-303, 2014

DOI for Biomarkers in Relation to the Effects of Ticagrelor in Comparison With Clopidogrel in Non-ST-Elevation Acute Coronary Syndrome Patients Managed With or Without In-Hospital Revascularization A Substudy From the Prospective Randomized Platelet Inhibition and Patient Outcomes (PLATO) Trial

Identification of Novel Downstream Molecules of Tissue Factor Activation by Comparative Proteomic Analysis

Kask, Lena; Jorsback, Anneli; Winkvist, Maria; Alfredsson, Jenny et al.

Part of Journal of Proteome Research, p. 477-488, 2014

DOI for Identification of Novel Downstream Molecules of Tissue Factor Activation by Comparative Proteomic Analysis

Cystatin C- and Creatinine-based Estimates of Renal Function and Their Value for Risk Prediction in Patients with Acute Coronary Syndrome: Results from the PLATelet Inhibition and Patient Outcomes (PLATO) Study

Åkerblom, Axel; Wallentin, Lars; Larsson, Anders; Siegbahn, Agneta et al.

Part of Clinical Chemistry, p. 1369-1375, 2013

DOI for Cystatin C- and Creatinine-based Estimates of Renal Function and Their Value for Risk Prediction in Patients with Acute Coronary Syndrome: Results from the PLATelet Inhibition and Patient Outcomes (PLATO) Study

Biomarkers in atrial fibrillation: a clinical review

Hijazi, Ziad; Oldgren, Jonas; Siegbahn, Agneta; Granger, Christopher B et al.

Part of European Heart Journal, p. 1475-1480, 2013

DOI for Biomarkers in atrial fibrillation: a clinical review

N-Terminal Pro-B-Type Natriuretic Peptide for Risk Assessment in Patients With Atrial Fibrillation: Insights from the ARISTOTLE trial

Hijazi, Ziad; Wallentin, Lars; Siegbahn, Agneta; Andersson, Ulrika et al.

Part of Journal of the American College of Cardiology, p. 2274-2284, 2013

DOI for N-Terminal Pro-B-Type Natriuretic Peptide for Risk Assessment in Patients With Atrial Fibrillation: Insights from the ARISTOTLE trial

Vitamin K antagonists in heart disease: Current status and perspectives (Section III)

De Caterina, Raffaele; Husted, Steen; Wallentin, Lars; Andreotti, Felicita et al.

Part of Thrombosis and Haemostasis, p. 1087-1107, 2013

DOI for Vitamin K antagonists in heart disease: Current status and perspectives (Section III)

General mechanisms of coagulation and targets of anticoagulants (Section I): Position Paper of the ESC Working Group on Thrombosis - Task Force on Anticoagulants in Heart Disease

De Caterina, R; Husted, S; Wallentin, Lars; Andreotti, F et al.

Part of Thrombosis and Haemostasis, p. 569-579, 2013

DOI for General mechanisms of coagulation and targets of anticoagulants (Section I): Position Paper of the ESC Working Group on Thrombosis - Task Force on Anticoagulants in Heart Disease

Parenteral anticoagulants in heart disease: Current status and perspectives (Section II) Position Paper of the ESC Working Group on Thrombosis - Task Force on Anticoagulants in Heart Disease

De Caterina, Raffaele; Husted, Steen; Wallentin, Lars; Andreotti, Felicita et al.

Part of Thrombosis and Haemostasis, p. 769-786, 2013

DOI for Parenteral anticoagulants in heart disease: Current status and perspectives (Section II) Position Paper of the ESC Working Group on Thrombosis - Task Force on Anticoagulants in Heart Disease

Common variants associated with plasma triglycerides and risk for coronary artery disease

Do, Ron; Willer, Cristen J.; Schmidt, Ellen M.; Sengupta, Sebanti et al.

Part of Nature Genetics, p. 1345-+, 2013

DOI for Common variants associated with plasma triglycerides and risk for coronary artery disease

Discovery and refinement of loci associated with lipid levels

Willer, Cristen J.; Schmidt, Ellen M.; Sengupta, Sebanti; Peloso, Gina M. et al.

Part of Nature Genetics, p. 1274-1283, 2013

DOI for Discovery and refinement of loci associated with lipid levels

Are There Any Causal Relations Between Growth Differentiation Factor 15 and Outcomes in Patients With Acute Coronary Syndrome?: - A Report From the Plato Gwas Study

Hagström, Emil; Eriksson, Niclas; Johansson, Åsa; Bertilsson, Maria et al.

Part of Circulation, 2013

GDF-15 for Prognostication of Cardiovascular and Cancer Morbidity and Mortality in Men

Wallentin, Lars; Zethelius, Bjorn; Berglund, Lars; Eggers, Kai M. et al.

Part of PLOS ONE, 2013

Genetic Polymorphism and Relationship to Cystatin C Concentrations and Outcome - Results From the Platelet Inhibition and Patient Outcomes Study

Åkerblom, Axel; Wallentin, Lars; Siegbahn, Agneta; Becker, Richard C. et al.

Part of Circulation, 2013

Large-scale association analysis identifies new risk loci for coronary artery disease

Deloukas, Panos; Kanoni, Stavroula; Willenborg, Christina; Farrall, Martin et al.

Part of Nature Genetics, p. 25-33, 2013

DOI for Large-scale association analysis identifies new risk loci for coronary artery disease

Evaluation of the Effect of Interleukin 18 Associated Genetic Polymorphisms on Risk of Cardiovascular Events in Patients With Acute Coronary Syndrome

Siegbahn, Agneta; Johansson, Åsa; Eriksson, Niclas; Hagström, Emil et al.

Part of Circulation, 2013

Evaluation of microparticles in whole blood by multicolour flow cytometry assay

Christersson, Christina; Johnell, Matilda; Siegbahn, Agneta

Part of Scandinavian Journal of Clinical and Laboratory Investigation, p. 229-239, 2013

DOI for Evaluation of microparticles in whole blood by multicolour flow cytometry assay

Tissue Factor non-coagulant signalling - molecular mechanisms and biological consequences with focus on cell migration and apoptosis

Åberg, Mikael; Siegbahn, Agneta

Part of Journal of Thrombosis and Haemostasis, p. 817-825, 2013

DOI for Tissue Factor non-coagulant signalling - molecular mechanisms and biological consequences with focus on cell migration and apoptosis

HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment

Cedervall, Jessica; Zhang, Yanyu; Ringvall, Maria; Thulin, Åsa et al.

Part of Angiogenesis, p. 889-902, 2013

DOI for HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment

Outcomes with ticagrelor versus clopidogrel in relation to high sensitivity troponin-T in non-ST-elevation acute coronary syndrome patients managed with early invasive or non-invasive treatment: a substudy from the prospective randomized PLATelet inhibit

Wallentin, Lars; James, Stefan; Giannitsis, Evangelos; Katus, Hugo et al.

Part of Pharmacotherapy, 2013

Response to Letter Regarding Article, "Cardiac Biomarkers Are Associated With an Increased Risk of Stroke and Death in Patients With Atrial Fibrillation: A Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Substudy"

Hijazi, Ziad; Oldgren, Jonas; Wallentin, Lars; Andersson, Ulrika et al.

Part of Circulation, 2013

DOI for Response to Letter Regarding Article, "Cardiac Biomarkers Are Associated With an Increased Risk of Stroke and Death in Patients With Atrial Fibrillation: A Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Substudy"

Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding

Paré, Guillaume; Eriksson, Niclas; Lehr, Thorsten; Connolly, Stuart et al.

Part of Circulation, p. 1404, 2013

DOI for Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding

High-sensitive cardiac troponin T and its relations to cardiovascular risk factors, morbidity, and mortality in elderly men

Eggers, Kai M.; Al-Shakarchi, Jinan; Berglund, Lars; Lindahl, Bertil et al.

Part of American Heart Journal, p. 541-+, 2013

DOI for High-sensitive cardiac troponin T and its relations to cardiovascular risk factors, morbidity, and mortality in elderly men

GDF-15 level in acute coronary syndrome and its relations to cardiovascular risk factors, disease manifestations, treatments and outcome - results from the PLATO-study

Wallentin, Lars; Bertilsson, Maria; Becker, R. C.; Himmelmann, A. et al.

Part of European Heart Journal, p. 733-733, 2013

DOI for GDF-15 level in acute coronary syndrome and its relations to cardiovascular risk factors, disease manifestations, treatments and outcome - results from the PLATO-study

Combining High Sensitivity Troponin I and T Measurements Improves Prediction of Long-Term Clinical Outcomes in Patients With Atrial Fibrillation - An Aristotle Substudy

Hijazi, Ziad; Siegbahn, Agneta; Andersson, Ulrika; Granger, Christopher B. et al.

Part of Circulation, 2013

The insulin-like growth factor 1 receptor mediates tissue factor/FVIIa-induced cell survival

Åberg, Mikael; Eriksson, Oskar; Mokhtari, Dariush; Siegbahn, Agneta

Part of Journal of Thrombosis and Haemostasis, p. 171-172, 2013

Proteomic analysis of tissue factor activation

Kask, Lena; Jorsback, A.; Winkvist, M.; Ek, B. et al.

Part of Journal of Thrombosis and Haemostasis, p. 379-380, 2013

Cystatin C and Estimated Glomerular Filtration Rate as Predictors for Adverse Outcome in Patients with ST-Elevation and Non-ST-Elevation Acute Coronary Syndromes: Results from the Platelet Inhibition and Patient Outcomes Study

Åkerblom, Axel; Wallentin, Lars; Siegbahn, Agneta; Becker, Richard C et al.

Part of Clinical Chemistry, p. 190-199, 2012

DOI for Cystatin C and Estimated Glomerular Filtration Rate as Predictors for Adverse Outcome in Patients with ST-Elevation and Non-ST-Elevation Acute Coronary Syndromes: Results from the Platelet Inhibition and Patient Outcomes Study

Cardiac Biomarkers Are Associated With an Increased Risk of Stroke and Death in Patients With Atrial Fibrillation: A Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Substudy

Hijazi, Ziad; Oldgren, Jonas; Andersson, Ulrika; Connolly, Stuart J. et al.

Part of Circulation, p. 1605-1616, 2012

DOI for Cardiac Biomarkers Are Associated With an Increased Risk of Stroke and Death in Patients With Atrial Fibrillation: A Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Substudy

Outcome and causes of renal deterioration evaluated by serial cystatin C measurements in acute coronary syndrome patients: Results from the PLATelet inhibition and patient Outcomes (PLATO) study

Åkerblom, Axel; Wallentin, Lars; Siegbahn, Agneta; Becker, R. C. et al.

Part of American Heart Journal, p. 728-734, 2012

DOI for Outcome and causes of renal deterioration evaluated by serial cystatin C measurements in acute coronary syndrome patients: Results from the PLATelet inhibition and patient Outcomes (PLATO) study

Usefulness of biomarkers for prognostication of outcome with early invasive or noninvasive treatment in non-st-elevation acute coronary syndromes - a substudy from the prospective randomized platelet inhibition and patient outcomes (PLATO) trial

Wallentin, Lars; James, Stefan; Giannitsis, Evangelos; Katus, Hugo et al.

Part of Journal of the American College of Cardiology, 2012

DOI for Usefulness of biomarkers for prognostication of outcome with early invasive or noninvasive treatment in non-st-elevation acute coronary syndromes - a substudy from the prospective randomized platelet inhibition and patient outcomes (PLATO) trial

Relations of growth-differentiation factor-15 to biomarkers reflecting vascular pathologies in a population-based sample of elderly subjects

Eggers, Kai M; Kempf, Tibor; Lind, Lars; Sundström, Johan et al.

Part of Scandinavian Journal of Clinical and Laboratory Investigation, p. 45-51, 2012

DOI for Relations of growth-differentiation factor-15 to biomarkers reflecting vascular pathologies in a population-based sample of elderly subjects

NT-proBNP for risk stratification in atrial fibrillation during treatment with apixaban or warfarin

Wallentin, Lars C.; Christersson, Christina; Siegbahn, Agneta; Schollin, M. et al.

Part of European Heart Journal, p. 51-51, 2012

DOI for NT-proBNP for risk stratification in atrial fibrillation during treatment with apixaban or warfarin

Increased levels of D-dimer identify patients with atrial fibrillation at high risk for bleeding an ARISTOTLE substudy

Siegbahn, Agneta; Christersson, Christina; Schollin, M.; Alexander, J. H. et al.

Part of European Heart Journal, p. 51-51, 2012

DOI for Increased levels of D-dimer identify patients with atrial fibrillation at high risk for bleeding an ARISTOTLE substudy

High sensitivity troponin-T for risk stratification in atrial fibrillation during treatment with apixaban or warfarin

Wallentin, Lars C.; Christersson, Christina; Siegbahn, Agneta; Schollin, M. et al.

Part of European Heart Journal, p. 53-53, 2012

DOI for High sensitivity troponin-T for risk stratification in atrial fibrillation during treatment with apixaban or warfarin

Serial cystatin C measurements and changes in glomerular filtration rate as predictors for death or myocardial infarction in ACS patients

Åkerblom, Axel; Wallentin, Lars; Siegbahn, Agneta; Becker, R. C. et al.

Part of European Heart Journal, p. 135-135, 2012

DOI for Serial cystatin C measurements and changes in glomerular filtration rate as predictors for death or myocardial infarction in ACS patients

Increased levels of D-dimer in atrial fibrillation identify patients with higher risk of thromboembolic events and death

Christersson, Christina; Schollin, M.; Alexander, J. H.; Bersh, B. J. et al.

Part of European Heart Journal, p. 969-969, 2012

DOI for Increased levels of D-dimer in atrial fibrillation identify patients with higher risk of thromboembolic events and death

A Detailed Cardiovascular Characterization of Obesity Without the Metabolic Syndrome

Lind, Lars; Siegbahn, Agneta; Ingelsson, Erik; Sundström, Johan et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, 2011

DOI for A Detailed Cardiovascular Characterization of Obesity Without the Metabolic Syndrome

Relationship between Clopidogrel-Induced Platelet P2Y₁₂ Inhibition and Stent Thrombosis or Myocardial Infarction after Percutaneous Coronary Intervention: A Case-Control Study

Varenhorst, Christoph; Koul, Sasha; Erlinge, David; Lagerqvist, Bo et al.

Part of American Heart Journal, p. 363-371, 2011

DOI for Relationship between Clopidogrel-Induced Platelet P2Y₁₂ Inhibition and Stent Thrombosis or Myocardial Infarction after Percutaneous Coronary Intervention: A Case-Control Study

Tissue Factor/ FVIIa prevents the extrinsic pathway of apoptosis by regulation of the tumor suppressor Death-Associated Protein Kinase 1 (DAPK1)

Åberg, Mikael; Johnell, Matilda; Wickström, Malin; Siegbahn, Agneta

Part of Thrombosis Research, p. 141-148, 2011

DOI for Tissue Factor/ FVIIa prevents the extrinsic pathway of apoptosis by regulation of the tumor suppressor Death-Associated Protein Kinase 1 (DAPK1)

Enhanced Platelet Activation Mediates the Accelerated Angiogenic Switch in Mice Lacking Histidine-Rich Glycoprotein

Ringvall, Maria; Thulin, Åsa; Zhang, Lei; Cedervall, Jessica et al.

Part of PLoS ONE, 2011

DOI for Enhanced Platelet Activation Mediates the Accelerated Angiogenic Switch in Mice Lacking Histidine-Rich Glycoprotein

ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing

Darmanis, Spyros; Nong, Rachel Yuan; Vänelid, Johan; Siegbahn, Agneta et al.

Part of PLOS ONE, 2011

DOI for ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing

Treatment with an Oral Direct Thrombin Inhibitor Decreases Platelet Activity but Increases Markers of Inflammation in Patients with Myocardial Infarction.

Christersson, Christina; Oldgren, Jonas; Wallentin, Lars; Siegbahn, Agneta

Part of Journal of Internal Medicine, p. 215-223, 2011

DOI for Treatment with an Oral Direct Thrombin Inhibitor Decreases Platelet Activity but Increases Markers of Inflammation in Patients with Myocardial Infarction.

Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial

Oldgren, Jonas; Budaj, Andrzej; Granger, Christopher B.; Khder, Yasser et al.

Part of European Heart Journal, p. 2781-2789, 2011

DOI for Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial

Growth-differentiation factor-15 for long-term risk prediction in patients stabilized after an episode of non-ST-segment-elevation acute coronary syndrome

Eggers, Kai M.; Kempf, Tibor; Lagerqvist, Bo; Lindahl, Bertil et al.

Part of Circulation: Cardiovascular Genetics, p. 88-96, 2010

DOI for Growth-differentiation factor-15 for long-term risk prediction in patients stabilized after an episode of non-ST-segment-elevation acute coronary syndrome

Sensitive plasma protein analysis by microparticle-based proximity ligation assays

Darmanis, Spyros; Nong, Rachel Yuan; Hammond, Maria; Gu, Jijuan et al.

Part of Molecular & Cellular Proteomics, p. 327-335, 2010

DOI for Sensitive plasma protein analysis by microparticle-based proximity ligation assays

Niemann-Pick C1 modulates hepatic triglyceride metabolism and its genetic variation contributes to serum triglyceride levels

Uronen, Riikka-Liisa; Lundmark, Per; Orho-Melander, Marju; Jauhiainen, Matti et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 1614-1620, 2010

DOI for Niemann-Pick C1 modulates hepatic triglyceride metabolism and its genetic variation contributes to serum triglyceride levels

The Influence of Direct Thrombin Inhibitors on the Formation of Platelet-leukocyte Aggregates and Tissue Factor Expression

Christersson, Christina; Johnell, Matilda; Siegbahn, Agneta

Part of Thrombosis Research, 2010

DOI for The Influence of Direct Thrombin Inhibitors on the Formation of Platelet-leukocyte Aggregates and Tissue Factor Expression

Platelet inhibition assessed with VerifyNow, flow cytometry and PlateletMapping in patients undergoing heart surgery

Alström, Ulrica; Granath, Fredrik; Oldgren, Jonas; Ståhle, Elisabeth et al.

Part of Thrombosis Research, p. 572-577, 2009

DOI for Platelet inhibition assessed with VerifyNow, flow cytometry and PlateletMapping in patients undergoing heart surgery

Assessment of P2Y(12) inhibition with the point-of-care device VerifyNow P2Y12 in patients treated with prasugrel or clopidogrel coadministered with aspirin

Varenhorst, Christoph; James, Stefan; Erlinge, David; Braun, Oscar O. et al.

Part of American Heart Journal, p. 5620-9, 2009

DOI for Assessment of P2Y(12) inhibition with the point-of-care device VerifyNow P2Y12 in patients treated with prasugrel or clopidogrel coadministered with aspirin

Activated platelets provide a functional microenvironment for the antiangiogenic fragment of histidine-rich glycoprotein

Thulin, Åsa; Ringvall, Maria; Dimberg, Anna; Kårehed, Karin et al.

Part of Molecular Cancer Research, p. 1792-1802, 2009

DOI for Activated platelets provide a functional microenvironment for the antiangiogenic fragment of histidine-rich glycoprotein

Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease

Varenhorst, Christoph; James, Stefan; Erlinge, David; Brandt, John T. et al.

Part of European Heart Journal, p. 1744-1752, 2009

DOI for Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease

Raised Interleukin-10 is an Indicator of Poor Outcome and Enhanced Systemic Inflammation in Patients with Acute Coronary Syndrome

Mälarstig, Anders; Eriksson, Per; Hamsten, Anders; Lindahl, Bertil et al.

Part of Heart, p. 724-9, 2008

DOI for Raised Interleukin-10 is an Indicator of Poor Outcome and Enhanced Systemic Inflammation in Patients with Acute Coronary Syndrome

Greater reduction of platelet activation markers and platelet-monocyte aggregates by prasugrel compared to clopidogrel in stable coronary artery disease

Braun, Oscar O.; Johnell, Matilda; Varenhorst, Christoph; James, Stefan et al.

Part of Thrombosis and Haemostasis, p. 626-633, 2008

DOI for Greater reduction of platelet activation markers and platelet-monocyte aggregates by prasugrel compared to clopidogrel in stable coronary artery disease

Simvastatin reduces the production of prothrombotic prostasomes in human prostate cancer cells

Åberg, Mikael; Johnell, Matilda; Wickström, Malin; Widunder, Anna et al.

Part of Thrombosis and Haemostasis, p. 655-662, 2008

DOI for Simvastatin reduces the production of prothrombotic prostasomes in human prostate cancer cells

TF/FVIIa transactivate PDGFRbeta to regulate PDGF-BB-induced chemotaxis in different cell types: involvement of Src and PLC

Siegbahn, Agneta; Johnell, Matilda; Nordin, Anna; Åberg, Mikael et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 135-41, 2008

DOI for TF/FVIIa transactivate PDGFRbeta to regulate PDGF-BB-induced chemotaxis in different cell types: involvement of Src and PLC

Simvastatin induces apoptosis in human breast cancer cells in a NFκB-dependent manner and abolishes the anti-apoptotic signaling of TF/FVIIa and TF/FVIIa/FXa

Åberg, Mikael; Wickström, Malin; Siegbahn, Agneta

Part of Thrombosis Research, p. 191-202, 2008

DOI for Simvastatin induces apoptosis in human breast cancer cells in a NFκB-dependent manner and abolishes the anti-apoptotic signaling of TF/FVIIa and TF/FVIIa/FXa

Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease

Wallentin, Lars; Varenhorst, Christoph; James, Stefan; Erlinge, David et al.

Part of European Heart Journal, p. 21-30, 2008

DOI for Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease

C-reactive protein and e-selectin levels are related to vasodilation in resistance, but not conductance arteries in the elderly: the prospective investigation of the Vasculature in Uppsala Seniors (PIVUS) study

Lind, Lars; Siegbahn, Agneta; Hulthe, Johannes; Elmgren, Anders

Part of Atherosclerosis, p. 129-137, 2008

DOI for C-reactive protein and e-selectin levels are related to vasodilation in resistance, but not conductance arteries in the elderly: the prospective investigation of the Vasculature in Uppsala Seniors (PIVUS) study

Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo

Erlinge, David; Varenhorst, Christoph; Braun, Oscar O; James, Stefan et al.

Part of Journal of the American College of Cardiology, p. 1968-77, 2008

DOI for Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo

Tissue factor and IL8 production by P-selectin-dependent platelet-monocyte aggregates in whole blood involves phosphorylation of Lyn and is inhibited by IL10

Christersson, Christina; Johnell, Matilda; Siegbahn, Agneta

Part of Journal of Thrombosis and Haemostasis, p. 986-994, 2008

DOI for Tissue factor and IL8 production by P-selectin-dependent platelet-monocyte aggregates in whole blood involves phosphorylation of Lyn and is inhibited by IL10

Activated coagulation in patients with shock due to ruptured abdominal aortic aneurysm

Skagius, Elisabeth; Siegbahn, Agneta; Bergqvist, David; Henriksson, A

Part of European Journal of Vascular and Endovascular Surgery, p. 37-40, 2008

DOI for Activated coagulation in patients with shock due to ruptured abdominal aortic aneurysm

Xa inhibition and coagulation activity: the influence of prolonged dalteparin treatment and gender in patients with acute coronary syndrome and healthy individuals

Oldgren, Jonas; Johnston, Nina; Siegbahn, Agneta

Part of American Heart Journal, p. 4930, 2008

DOI for Xa inhibition and coagulation activity: the influence of prolonged dalteparin treatment and gender in patients with acute coronary syndrome and healthy individuals

Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction

Mälarstig, Anders; Sigurdsson, Snaevar; Eriksson, Per; Paulsson-Berne, Gabrielle et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 975-982, 2008

DOI for Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction

Early decrease in coagulation activity after myocardial infarction is associated with lower risk of new ischemic events: Observations from the ESTEEM trial

Christersson, Christina; Oldgren, Jonas; Bylock, Anders; Siegbahn, Agneta et al.

Part of European Heart Journal, p. 692-698, 2007

DOI for Early decrease in coagulation activity after myocardial infarction is associated with lower risk of new ischemic events: Observations from the ESTEEM trial

The intersubject variability of tissue factor mRNA production in human monocytes: relation with the toll-like receptor 4

Mälarstig, Anders; Siegbahn, Agneta

Part of Thrombosis Research, p. 407-413, 2007

DOI for The intersubject variability of tissue factor mRNA production in human monocytes: relation with the toll-like receptor 4

Growth Differentiation Factor 15 for Risk Stratification and Selection of an Invasive Treatment Strategy in Non-ST-Elevation Acute Coronary Syndrome

Wollert, Kai C; Kempf, Tibor; Lagerqvist, Bo; Lindahl, Bertil et al.

Part of Circulation, p. 1540-1548, 2007

DOI for Growth Differentiation Factor 15 for Risk Stratification and Selection of an Invasive Treatment Strategy in Non-ST-Elevation Acute Coronary Syndrome

Fibrinolysis in patients with abdominal aortic aneurysm with special emphasis on rupture and shock

Skagius, E; Siegbahn, Agneta; Bergqvist, David; Henriksson, A E

Part of Journal of Thrombosis and Haemostasis, p. 147-150, 2007

DOI for Fibrinolysis in patients with abdominal aortic aneurysm with special emphasis on rupture and shock

Early decrease in coagulation activity after myocardial infarction is associated with lower risk of new ischaemic events: observations from the ESTEEM: Reply

Christersson, Christina; Oldgren, Jonas; Bylock, Anders; Siegbahn, Agneta et al.

Part of European Heart Journal, p. 1783-1783, 2007

DOI for Early decrease in coagulation activity after myocardial infarction is associated with lower risk of new ischaemic events: observations from the ESTEEM: Reply

Lipoprotein-associated phospholipase A2 does not predict mortality or new ischaemic events in acute coronary syndrome patients

Oldgren, Jonas; James, Stefan; Siegbahn, Agneta; Wallentin, Lars

Part of European Heart Journal, p. 699-704, 2007

DOI for Lipoprotein-associated phospholipase A2 does not predict mortality or new ischaemic events in acute coronary syndrome patients

The platelet inhibiting effect of a clopidogrel bolus dose in patients on long-term acetylsalicylic acid treatment

Alström, Ulrica; Tydén, Hans; Oldgren, Jonas; Siegbahn, Agneta et al.

Part of Thrombosis Research, p. 353-359, 2007

DOI for The platelet inhibiting effect of a clopidogrel bolus dose in patients on long-term acetylsalicylic acid treatment

Genetic variation in the interleukin-6 gene in relation to risk and outcomes in acute coronary syndrome

Mälarstig, Anders; Wallentin, Lars; Siegbahn, Agneta

Part of Thrombosis Research, p. 467-473, 2007

DOI for Genetic variation in the interleukin-6 gene in relation to risk and outcomes in acute coronary syndrome

Improved identification of patients with coronary artery disease by the use of new lipid and lipoprotein biomarkers

Johnston, Nina; Jernberg, Tomas; Lagerqvist, Bo; Siegbahn, Agneta et al.

Part of American Journal of Cardiology, p. 640-5, 2006

DOI for Improved identification of patients with coronary artery disease by the use of new lipid and lipoprotein biomarkers

Oxidized low-density lipoprotein as a predictor of outcome in patients with unstable coronary artery disease

Johnston, Nina; Jernberg, Tomas; Lagerqvist, Bo; Siegbahn, Agneta et al.

Part of International Journal of Cardiology, p. 167-173, 2006

DOI for Oxidized low-density lipoprotein as a predictor of outcome in patients with unstable coronary artery disease

Soluble CD40L levels are regulated by the -3459 A>G polymorphism and predict myocardial infarction and the efficacy of antithrombotic treatment in non-ST elevation acute coronary syndrome

Mälarstig, Anders; Lindahl, Bertil; Wallentin, Lars; Siegbahn, Agneta

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 1667-1673, 2006

DOI for Soluble CD40L levels are regulated by the -3459 A>G polymorphism and predict myocardial infarction and the efficacy of antithrombotic treatment in non-ST elevation acute coronary syndrome

Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease

Jernberg, Tomas; Payne, Christopher D.; Winters, Kenneth J.; Darstein, Christelle et al.

Part of European Heart Journal, p. 1166-1173, 2006

DOI for Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease

Low molecular weight dextran sulfate: a strong candidate drug to block IBMIR in clinical islet transplantation

Johansson, H.; Goto, M.; Dufrane, D.; Siegbahn, Agneta et al.

Part of American Journal of Transplantation, p. 305-12, 2006

DOI for Low molecular weight dextran sulfate: a strong candidate drug to block IBMIR in clinical islet transplantation

Troponin-T and N-terminal pro-B-type natriuretic peptide predict mortality benefit from coronary revascularization in acute coronary syndromes: a GUSTO-IV substudy

James, Stefan K.; Lindbäck, Johan; Tilly, Johanna; Siegbahn, Agneta et al.

Part of Journal of the American College of Cardiology, p. 1146-1154, 2006

DOI for Troponin-T and N-terminal pro-B-type natriuretic peptide predict mortality benefit from coronary revascularization in acute coronary syndromes: a GUSTO-IV substudy

Usefulness of biomarkers for predicting long-term mortality in patients with diabetes mellitus and non-ST-elevation acute coronary syndromes (A GUSTO IV substudy)

James, Stefan K.; Lindahl, Bertil; Timmer, Jorik R.; Ottervanger, Jan Paul et al.

Part of American Journal of Cardiology, p. 167-172, 2006

DOI for Usefulness of biomarkers for predicting long-term mortality in patients with diabetes mellitus and non-ST-elevation acute coronary syndromes (A GUSTO IV substudy)

Improved identification of patients with coronary artery disease by the use of new lipid and lipoprotein biomarkers

Johnston, Nina; Jernberg, Tomas; Lagerqvist, Bo; Siegbahn, Agneta et al.

Part of American Journal of Cardiology, p. 640-5, 2006

Regulation of chemotaxis by the cytoplasmic domain of tissue factor

Siegbahn, Agneta; Johnell, Matilda; Sorensen, Brit B.; Petersen, Lars C. et al.

Part of Thrombosis and Haemostasis, p. 27-34, 2005

DOI for Regulation of chemotaxis by the cytoplasmic domain of tissue factor

An acute inflammatory reaction induced by myocardial damage is superimposed on a chronic inflammation in unstable coronary artery disease

James, Stefan K; Oldgren, Jonas; Lindbäck, Johan; Johnston, Nina et al.

Part of American Heart Journal, p. 619-626, 2005

DOI for An acute inflammatory reaction induced by myocardial damage is superimposed on a chronic inflammation in unstable coronary artery disease

FRISC score for selection of patients for an early invasive treatment strategy in unstable coronary artery disease

Lagerqvist, B; Diderholm, E; Lindahl, B; Husted, S et al.

Part of Heart, p. 1047-1052, 2005

DOI for FRISC score for selection of patients for an early invasive treatment strategy in unstable coronary artery disease

Influence of prolonged dalteparin treatment on coagulation, fibrinolysis and inflammation in unstable coronary artery disease

Oldgren, Jonas; Fellenius, C.; Boman, K.; Jansson, J-H. et al.

Part of Journal of Internal Medicine, p. 420-7, 2005

DOI for Influence of prolonged dalteparin treatment on coagulation, fibrinolysis and inflammation in unstable coronary artery disease

Genetic variations in the tissue factor gene are associated with clinical outcome in acute coronary syndrome and expression levels in human monocytes

Mälarstig, Anders; Tenno, Taavo; Johnston, Nina; Lagerqvist, Bo et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2667-2672, 2005

DOI for Genetic variations in the tissue factor gene are associated with clinical outcome in acute coronary syndrome and expression levels in human monocytes

Long-term treatment with ximelagatran, an oral direct thrombin inhibitor, persistently reduces the coagulation activity after a myocardial infarction

Christersson, Christina; Oldgren, Jonas; Bylock, A.; Wallentin, Lars et al.

Part of Journal of Thrombosis and Haemostasis, p. 2245-53, 2005

DOI for Long-term treatment with ximelagatran, an oral direct thrombin inhibitor, persistently reduces the coagulation activity after a myocardial infarction

Activation of the inflammation, coagulation, and fibrinolysis systems, without influence of abciximab infusion in patients with non-ST–elevation acute coronary syndromes treated with dalteparin: a GUSTO IV substudy

James, Stefan K.; Siegbahn, Agneta; Armstrong, P; Barnathan, E et al.

Part of American Heart Journal, p. 267-274, 2004

DOI for Activation of the inflammation, coagulation, and fibrinolysis systems, without influence of abciximab infusion in patients with non-ST–elevation acute coronary syndromes treated with dalteparin: a GUSTO IV substudy

[Prognosis in unstable coronary artery disease. Multimarker strategy is the best basis for the therapeutic choice]

James, Stefan; Lindahl, Bertil; Siegbahn, Agneta; Stridsberg, Mats et al.

Part of Lakartidningen, p. 1514-9, 1521, 2004

Activation of coagulation and fibrinolytic systems in patients with CLI is not normalized after surgical revascularisation.

Pärsson, H; Holmberg, A; Siegbahn, A; Bergqvist, D

Part of Eur J Vasc Endovasc Surg, p. 186-92, 2004

Myocardial damage, coagulation activity and the response to thrombin inhibition in unstable coronary artery disease.

Oldgren, Jonas; Siegbahn, Agneta; Grip, Lars; Linder, Rikard et al.

Part of Thromb Haemost, p. 381-7, 2004

CRP and IL-6 concentrations are associated with poor glycemic control despite preserved beta-cell function during the first year after diagnosis of type 1 diabetes.

Schölin, Anna; Siegbahn, Agneta; Lind, Lars; Berne, Christian et al.

Part of Diabetes Metab Res Rev, p. 205-10, 2004

Expression of fibrinolytic and coagulation factors in cocultured human endothelial and smooth muscle cells.

Helenius, Gisela; Heydarkhan-Hagvall, Sepideh; Siegbahn, Agneta; Risberg, Bo

Part of Tissue Eng, p. 353-60, 2004

PML/RARalpha plays a role for basal activity and retinoid-induced repression of the tissue factor promoter in acute promyelocytic leukemia cells

Tenno, Taavo; Öberg, Fredrik; Mackman, Nigel; Nilsson, Kenneth et al.

Part of Thrombosis and Haemostasis, p. 930-9, 2003

Low utilisation of unactivated protein C in a patient with meningococcal septic shock and disseminated intravascular coagulation

Lignell, Anders; Siegbahn, Agneta; Stridsberg, Mats; Pauksen, Karlis et al.

Part of Acta Anaesthesiologica Scandinavica, p. 897-900, 2003

DOI for Low utilisation of unactivated protein C in a patient with meningococcal septic shock and disseminated intravascular coagulation

N-Terminal Pro–Brain Natriuretic Peptide and Other Risk Markers for the Separate Prediction of Mortality and Subsequent Myocardial Infarction in Patients With Unstable Coronary Artery Disease: A Global Utilization of Strategies To Open occluded arteries (GUSTO)-IV Substudy

James, Stefan; Lindahl, Bertil; Siegbahn, Agneta; Stridsberg, Mats et al.

Part of Circulation, p. 275-281, 2003

DOI for N-Terminal Pro–Brain Natriuretic Peptide and Other Risk Markers for the Separate Prediction of Mortality and Subsequent Myocardial Infarction in Patients With Unstable Coronary Artery Disease: A Global Utilization of Strategies To Open occluded arteries (GUSTO)-IV Substudy

Myocardial Damage, Inflammation and Thrombin Inhibition in Unstable Coronary Artery Disease

Oldgren, Jonas; Wallentin, Lars; Grip, L; Linder, R et al.

Part of European Heart Journal, p. 86-93, 2003

DOI for Myocardial Damage, Inflammation and Thrombin Inhibition in Unstable Coronary Artery Disease

A quantitative real-time PCR method for tissue factor mRNA

Mälarstig, Anders; Tenno, Taavo; Jossan, Surinder; Åberg, Mikael et al.

Part of Thrombosis Research, p. 175-83, 2003

DOI for A quantitative real-time PCR method for tissue factor mRNA

N-terminal pro-brain natriuretic peptide in relation to inflammation, myocardial necrosis, and the effect of an invasive strategy in unstable coronary artery disease.

Jernberg, Tomas; Lindahl, Bertil; Siegbahn, Agneta; Andren, Bertil et al.

Part of J Am Coll Cardiol, p. 1909-16, 2003

Low molecular weight heparin (dalteparin) compared to unfractionated heparin as an adjunct to rt-PA (alteplase) for improvement of coronary artery patency in acute myocardial infarction-the ASSENT Plus study.

Wallentin, Lars; Bergstrand, Lott; Dellborg, Mikael; Fellenius, Carin et al.

Part of Eur Heart J, p. 897-908, 2003

Coagulation, fibrinolysis and cell activation in patients and shed mediastinal blood during coronary artery bypass grafting using a new heparin-coated surface

Johnell, Matilda; Elgue, Graciela; Larsson, Rolf; Larsson, Anders et al.

Part of Journal of Thoracic and Cardiovascular Surgery, p. 321-332, 2002

DOI for Coagulation, fibrinolysis and cell activation in patients and shed mediastinal blood during coronary artery bypass grafting using a new heparin-coated surface

Cell adhesion and tissue factor upregulation in oxygenators used during coronary artery bypass grafting are modified by the Corline Heparin Surface

Johnell, Matilda; Elgue, Graciela; Thelin, Stefan; Larsson, Rolf et al.

Part of Scandinavian Cardiovascular Journal, p. 351-357, 2002

DOI for Cell adhesion and tissue factor upregulation in oxygenators used during coronary artery bypass grafting are modified by the Corline Heparin Surface

Influence on coagulation activity by subcutaneous LMW heparin as an adjuvant treatment to fibrinolysis in acute myocardial infarction.

Frostfeldt, Gunnar; Gustavsson, Gunnar; Lindahl, Bertil; Nygren, Anders et al.

Part of Thromb Res, p. 193-9, 2002

Tissue factor regulation and cytokine expression in monocyte-endothelial cell co-cultures: effects of a statin, an ACE-inhibitor and a low-molecular-weight heparin.

Lindmark, Eva; Siegbahn, Agneta

Part of Thromb Res, p. 77-84, 2002

Relationship between interleukin 6 and mortality in patients with unstable coronary artery disease: effects of an early invasive or noninvasive strategy.

Lindmark, E; Diderholm, E; Wallentin, L; Siegbahn, A

Part of JAMA, p. 2107-13, 2001

No benefit of reduced heparinization in thoracic aortic operation with heparin-coated bypass circuits

Olsson, Christian; Siegbahn, Agneta; Haldén, Eric; Nilsson, Bo et al.

Part of Annals of Thoracic Surgery, p. 743-749, 2000

DOI for No benefit of reduced heparinization in thoracic aortic operation with heparin-coated bypass circuits

Heparin-coated cardiopulmonary bypass circuits reduce circulating complement factors and interleukin-6 in paediatric heart surgery

Olsson, Christian; Siegbahn, Agneta; Henze, Axel; Nilsson, Bo et al.

Part of Scandinavian Cardiovascular Journal, p. 33-40, 2000

Binding of factor VIIa to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB-stimulated chemotaxis.

Siegbahn, A; Johnell, M; Rorsman, C; Ezban, M et al.

Part of Blood, p. 3452-8, 2000

Cellular consequences upon factor VIIa binding to tissue factor.

Siegbahn, A

Part of Haemostasis, p. 41-7, 2000

Overactivation of phospholipase C-gamma1 renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis

Rönnstrand, Lars; Siegbahn, Agneta; Rorsman, Charlotte; Johnell, Matilda et al.

Part of Journal of Biological Chemistry, p. 22089-22094, 1999

DOI for Overactivation of phospholipase C-gamma1 renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis

Mutation of a Src phosphorylation site in the PDGF beta-receptor leads to increased PDGF-stimulated chemotaxis but decreased mitogenesis

Hansen, Klaus; Johnell, Matilda; Siegbahn, Agneta; Rorsman, Charlotte et al.

Part of EMBO Journal, p. 5299-5313, 1996

A unique autophosphorylation site in the platelet-derived growth factor alpha receptor from a heterodimeric receptor complex

Rupp, Eva; Siegbahn, Agneta; Rönnstrand, Lars; Wernstedt, Christer et al.

Part of European Journal of Biochemistry, p. 29-41, 1994

Epstein-Barr virus (EBV) can immortalize B-cll cells activated by cytokines.

Wendel-Hansen, V; Sällström, J; De Campos-Lima, P O; Kjellström, G et al.

Part of Leukemia, p. 476-84, 1994

Hemostasis profile and lipid metabolism with long-interval use of a desogestrel-containing oral contraceptive.

Cachrimanidou, A C; Hellberg, D; Nilsson, S; von Schoulz, B et al.

Part of Contraception, p. 153-65, 1994

Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase.

Wennström, S; Siegbahn, A; Yokote, K; Arvidsson, A K et al.

Part of Oncogene, p. 651-60, 1994

Stem cell factor is a chemotactic factor for human mast cells.

Nilsson, G; Butterfield, J H; Nilsson, K; Siegbahn, A

Part of J Immunol, p. 3717-23, 1994

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

Waltenberger, J; Claesson-Welsh, L; Siegbahn, A; Shibuya, M et al.

Part of J Biol Chem, p. 26988-95, 1994

The influence of pretransplant lipoprotein abnormalities on the early results of renal transplantation.

Dimény, E; Tufveson, G; Lithell, H; Larsson, E et al.

Part of Eur J Clin Invest, p. 572-9, 1993

Increased Kit/SCF receptor induced mitogenicity but abolished cell motility after inhibition of protein kinase C.

Blume-Jensen, P; Siegbahn, A; Stabel, S; Heldin, C H et al.

Part of EMBO J, p. 4199-209, 1993

Platelet-derived growth factor is angiogenic in vivo

Risau, W; Drexler, H; Mironov, V; Smits, Anja et al.

Part of Growth Factors, p. 261-266, 1992

Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes

Heldin, Carl-Henrik; Östman, Arne; Eriksson, Anders; Siegbahn, Agneta et al.

Part of Kidney International, p. 571-574, 1992

DOI for Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes

PDGF alpha- and beta-receptors activate unique and common signal transduction pathways.

Eriksson, A; Siegbahn, A; Westermark, B; Heldin, C H et al.

Part of EMBO J, p. 543-50, 1992

Supplementation with n-3 fatty acids reduces triglycerides but increases PAI-1 in non-insulin-dependent diabetes mellitus.

Boberg, M; Pollare, T; Siegbahn, A; Vessby, B

Part of Eur J Clin Invest, p. 645-50, 1992

Neomycin is a platelet-derived growth factor (PDGF) antagonist that allows discrimination of PDGF alpha- and beta-receptor signals in cells expressing both receptor types.

Vassbotn, F S; Ostman, A; Siegbahn, A; Holmsen, H et al.

Part of J Biol Chem, p. 15635-41, 1992

Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis

Blume-Jensen, Peter; Claesson-Welsh, Lena; Siegbahn, Agneta; Zsebo, Krisztina M. et al.

Part of EMBO Journal, p. 4121-4128, 1991

Effects of dietary supplementation with vitamin E on human neutrophil chemotaxis and generation of LTB4.

Luostarinen, R; Siegbahn, A; Saldeen, T

Part of Ups J Med Sci, p. 103-11, 1991

B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase.

Westermark, B; Siegbahn, A; Heldin, C H; Claesson-Welsh, L

Part of Proc Natl Acad Sci U S A, p. 128-32, 1990

Primary haemostasis, plasmatic coagulation and fibrinolysis in renal transplantation.

Fellström, B; Siegbahn, A; Liljenberg, G; Haglund, O et al.

Part of Thromb Res, p. 97-104, 1990

Coagulation and fibrinolysis during the normal menstrual cycle

Siegbahn, Agneta; Odlind, V.; Hedner, U.; Venge, Per

Part of Upsala Journal of Medical Sciences, p. 137-152, 1989

Subcutaneous treatment of deep venous thrombosis with low molecular weight heparin. A dose finding study with LMWH-Novo.

Siegbahn, A; Y-Hassan, S; Boberg, J; Bylund, H et al.

Part of Thromb Res, p. 767-78, 1989

A glioma-derived PDGF A chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets.

Nistér, M; Hammacher, A; Mellström, K; Siegbahn, A et al.

Part of Cell, p. 791-9, 1988

Age dependence of blood fibrinolytic components and the effects of low-dose oral contraceptives on coagulation and fibrinolysis in teenagers.

Siegbahn, A; Ruusuvaara, L

Part of Thromb Haemost, p. 361-4, 1988

Specific binding of B-CLL cell-derived chemokinetic inhibitory factor (CIF) to human polymorphonuclear leukocytes

Siegbahn, Agneta; Garcia, R. C.; Kishi, K.; Nilsson, K. et al.

Part of European Journal of Haematology, p. 172-179, 1987

Production of chemokinetic inhibitory factor (CIF) by normal blood and spleen B lymphocytes

Siegbahn, Agneta; Rosén, A.; Venge, Per; Aman, P. et al.

Part of Leukemia Research, p. 179-186, 1986

The chemokinetic inhibitory factor derived from chronic lymphocytic leukaemia cells: Partial purification and characterization of a new lymphokine

Siegbahn, Agneta; Nilsson, K.; Venge, Per

Part of Scandinavian Journal of Immunology, p. 15-23, 1986

The chemokinetic inhibitory factor (CIF) in serum of CLL patients: correlation with infection propensity and disease activity

Siegbahn, Agneta; Simonsson, B.; Venge, Per

Part of Scandinavian journal of haematology, p. 80-87, 1985

Prognostic value of serum lactic dehydrogenase in non-Hodgkin's lymphoma.

Hagberg, H; Siegbahn, A

Part of Scand J Haematol, p. 49-56, 1983

Cellular origin of the chemokinetic inhibitor of polymorphononuclear leucocytes found in sera from patients with chronic lymphocytic leukaemia

Siegbahn, Agneta; Venge, Per; Nilsson, K.

Part of Scandinavian journal of haematology, p. 184-192, 1983

Identification of a chemokinetic inhibitor in serum from patients with chronic lymphocytic leukaemia

Siegbahn, Agneta; Venge, Per; Nilsson, K.; Simonson, B.

Part of Scandinavian journal of haematology, p. 122-131, 1982

Biomarkers in addition to clinical characteristics for prediction of peripheral artery disease in patients with recent myocardial infarction

Jönelid, Birgitta; Christersson, Christina; Hedberg, P; Leppert, Jerzy et al.

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