Anja Sandström

Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

Akaberi, Dario; Pourghasemi, Monireh; Krambrich, Janina; Berger, Julia et al.

Part of Antimicrobial Agents and Chemotherapy, p. 1-18, 2024

• DOI for Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
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Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors

Benediktsdottir, Andrea; Sooriyaarachchi, Sanjeewani; Cao, Sha; Ottosson, Nina E. et al.

Part of European Journal of Medicinal Chemistry, 2024

• DOI for Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors
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Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses

Luttens, Andreas; Gullberg, Hjalmar; Abdurakhmanov, Eldar; Vo, Duy Duc et al.

Part of Journal of the American Chemical Society, p. 2905-2920, 2022

• DOI for Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses
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Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation

Benediktsdottir, Andrea; Lu, Lu; Cao, Sha; Zamaratski, Edouard et al.

Part of European Journal of Medicinal Chemistry, 2021

• DOI for Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation
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Targeting the NS2B-NS3 protease of tick-borne encephalitis virus with pan-flaviviral protease inhibitors

Akaberi, Dario; Bahlstrom, Amanda; Chinthakindi, Praveen K.; Nyman, Tomas et al.

Part of Antiviral Research, 2021

• DOI for Targeting the NS2B-NS3 protease of tick-borne encephalitis virus with pan-flaviviral protease inhibitors

Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

Akaberi, Dario; Pourghasemi, Monireh; Krambrich, Janina; Berger, Julia et al.

Part of Antimicrobial Agents and Chemotherapy, p. 1-18, 2024

• DOI for Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
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Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors

Benediktsdottir, Andrea; Sooriyaarachchi, Sanjeewani; Cao, Sha; Ottosson, Nina E. et al.

Part of European Journal of Medicinal Chemistry, 2024

• DOI for Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors
• Download full text (pdf) of Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors

Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses

Luttens, Andreas; Gullberg, Hjalmar; Abdurakhmanov, Eldar; Vo, Duy Duc et al.

Part of Journal of the American Chemical Society, p. 2905-2920, 2022

• DOI for Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses
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Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation

Benediktsdottir, Andrea; Lu, Lu; Cao, Sha; Zamaratski, Edouard et al.

Part of European Journal of Medicinal Chemistry, 2021

• DOI for Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation
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Targeting the NS2B-NS3 protease of tick-borne encephalitis virus with pan-flaviviral protease inhibitors

Akaberi, Dario; Bahlstrom, Amanda; Chinthakindi, Praveen K.; Nyman, Tomas et al.

Part of Antiviral Research, 2021

• DOI for Targeting the NS2B-NS3 protease of tick-borne encephalitis virus with pan-flaviviral protease inhibitors

The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain

Nyman, Julia; Guo, Ning; Sandström, Anja; Hallberg, Mathias et al.

Part of European Journal of Pharmacology, 2021

• DOI for The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain

Solid Phase Synthesis of Sulfonimidamide Pseudopeptides and Library Generation

Chinthakindi, Praveen K.; Benediktsdottir, Andrea; Arvidsson, Per I; Chen, Yantao et al.

Part of European Journal of Organic Chemistry, p. 3796-3807, 2020

• DOI for Solid Phase Synthesis of Sulfonimidamide Pseudopeptides and Library Generation
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Identification of a C2-symmetric diol based human immunodeficiency virus protease inhibitor targeting Zika virus NS2B-NS3 protease

Akaberi, Dario; Chinthakindi, Praveen K.; Båhlström, Amanda; Palanisamy, Navaneethan et al.

Part of Journal of Biomolecular Structure and Dynamics, p. 5526-5536, 2020

• DOI for Identification of a C2-symmetric diol based human immunodeficiency virus protease inhibitor targeting Zika virus NS2B-NS3 protease
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Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

Part of RSC Medicinal chemistry, p. 234-244, 2020

• DOI for Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

Synthesis of Sulfonimidamide-Based Amino Acid Building Blocks with Orthogonal Protecting Groups

Chinthakindi, Praveen K.; Benediktsdottir, Andrea; Ibrahim, Ayah; Wared, Atta et al.

Part of European Journal of Organic Chemistry, p. 1045-1057, 2019

• DOI for Synthesis of Sulfonimidamide-Based Amino Acid Building Blocks with Orthogonal Protecting Groups

An imidazole based H-Phe-Phe-NH2 peptidomimetic with anti-allodynic effect in spared nerve injury mice

Skogh, Anna; Lesniak, Anna; Sköld, Christian; Karlgren, Maria et al.

Part of Bioorganic & Medicinal Chemistry Letters, p. 2446-2450, 2018

• DOI for An imidazole based H-Phe-Phe-NH2 peptidomimetic with anti-allodynic effect in spared nerve injury mice

Pan-NS3 protease inhibitors of hepatitis C virus based on an R3-elongated pyrazinone scaffold

Belfrage, Anna Karin; Abdurakhmanov, Eldar; Åkerblom, Eva; Brandt, Peter et al.

Part of European Journal of Medicinal Chemistry, p. 453-464, 2018

• DOI for Pan-NS3 protease inhibitors of hepatitis C virus based on an R3-elongated pyrazinone scaffold

Impact of N-methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration

Skogh, Anna; Lesniak, Anna; Gaugaz, Fabienne Z.; Svensson, Richard et al.

Part of European Journal of Pharmaceutical Sciences, p. 533-540, 2017

• DOI for Impact of N-methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration

Palladium-Catalyzed Aminocarbonylation in Solid-Phase Peptide Synthesis: A Method for Capping, Cyclization, and Isotope Labeling

Skogh, Anna; Friis, Stig D.; Skrydstrup, Troels; Johansson, Anja

Part of Organic Letters, p. 2873-2876, 2017

• DOI for Palladium-Catalyzed Aminocarbonylation in Solid-Phase Peptide Synthesis: A Method for Capping, Cyclization, and Isotope Labeling

Importance of N-and C-terminal residues of substance P 1-7 for alleviating allodynia in mice after peripheral administration

Skogh, Anna; Lesniak, Anna; Gaugaz, Fabienne Z.; Svensson, Richard et al.

Part of European Journal of Pharmaceutical Sciences, p. 345-351, 2017

• DOI for Importance of N-and C-terminal residues of substance P 1-7 for alleviating allodynia in mice after peripheral administration

Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

Belfrage, Anna Karin; Abdurakhmanov, Eldar; Åkerblom, Eva; Brandt, Peter et al.

Part of Bioorganic & Medicinal Chemistry, p. 2603-2620, 2016

• DOI for Discovery of pyrazinone based compounds that potently inhibit the drug resistant enzyme variant R155K of the hepatitis C virus NS3 protease

Small constrained SP_1-7 analogues bind to a unique site and promote anti-allodynic effects following systemic injection in mice

Jonsson, Anna; Fransson, Rebecca; Haramaki, Yutaka; Skogh, Anna et al.

Part of Neuroscience, p. 112-119, 2015

• DOI for Small constrained SP_1-7 analogues bind to a unique site and promote anti-allodynic effects following systemic injection in mice

Preclinical Characterization of Acyl Sulfonimidamides: Potential Carboxylic Acid Bioisosteres with Tunable Properties

Borhade, Sanjay R.; Svensson, Richard; Brandt, Peter; Artursson, Per et al.

Part of ChemMedChem, p. 455-460, 2015

• DOI for Preclinical Characterization of Acyl Sulfonimidamides: Potential Carboxylic Acid Bioisosteres with Tunable Properties

Synthesis of Vinyl- and Aryl–Acyl Sulfonimidamides Through Pd-Catalyzed Carbonylation Using Mo(CO)₆ as ex situ CO Source

Wakchaure, Prasad; Borhade, Sanjay; Sandström, Anja; Arvidsson, Per

Part of European Journal of Organic Chemistry, p. 213-219, 2015

• DOI for Synthesis of Vinyl- and Aryl–Acyl Sulfonimidamides Through Pd-Catalyzed Carbonylation Using Mo(CO)₆ as ex situ CO Source

Efficient and Selective Palladium-Catalysed C-3 Urea Couplings to 3,5-Dichloro-2(1H)-pyrazinones

Belfrage, Anna Karin; Gising, Johan; Svensson, Fredrik; Åkerblom, Eva et al.

Part of European Journal of Organic Chemistry, p. 978-986, 2015

• DOI for Efficient and Selective Palladium-Catalysed C-3 Urea Couplings to 3,5-Dichloro-2(1H)-pyrazinones

Palladium-Catalyzed Carbonylation of Aryl Iodides with Sulfinamides

Belfrage, Anna Karin; Wakchaure, Prasad; Larhed, Mats; Sandström, Anja

Part of European Journal of Organic Chemistry, p. 7069-7074, 2015

• DOI for Palladium-Catalyzed Carbonylation of Aryl Iodides with Sulfinamides

Vinylated linear P2 pyrimidinyloxyphenylglycine based inhibitors of the HCV NS3/4A protease and corresponding macrocycles

Lampa, Anna; Alogheli, Hiba; Ehrenberg, Angelica E.; Åkerblom, Eva et al.

Part of Bioorganic & Medicinal Chemistry, p. 6595-6615, 2014

• DOI for Vinylated linear P2 pyrimidinyloxyphenylglycine based inhibitors of the HCV NS3/4A protease and corresponding macrocycles

Exploration and pharmacokinetic profiling of phenylalanine based carbamates as novel substance p 1-7 analogues

Fransson, Rebecca; Nordvall, Gunnar; Bylund, Johan; Carlsson-Jonsson, Anna et al.

Part of ACS Medicinal Chemistry Letters, p. 1272-1277, 2014

• DOI for Exploration and pharmacokinetic profiling of phenylalanine based carbamates as novel substance p 1-7 analogues

Novel Peptidomimetic Hepatitis C Virus NS3/4A Protease Inhibitors Spanning the P2–P1′ Region

Lampa, Anna; Bergman, Sara; Svahn Gustafsson, Sofia; Alogheli, Hiba et al.

Part of ACS Medicinal Chemistry Letters, p. 249-254, 2014

• DOI for Novel Peptidomimetic Hepatitis C Virus NS3/4A Protease Inhibitors Spanning the P2–P1′ Region

Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket

Gising, Johan; Belfrage, Anna Karin; Alogheli, Hiba; Ehrenberg, Angelica et al.

Part of Journal of Medicinal Chemistry, p. 1790-1801, 2014

• DOI for Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket

N-terminal truncations of substance P_1-7 amide affect its action on spinal cord injury-induced mechanical allodynia in rats

Carlsson-Jonsson, Anna; Gao, Tianle; Hao, Jing-Xia; Fransson, Rebecca et al.

Part of European Journal of Pharmacology, p. 319-325, 2014

• DOI for N-terminal truncations of substance P_1-7 amide affect its action on spinal cord injury-induced mechanical allodynia in rats

Aminocarbonylation of 4-Iodo-1H-imidazoles with an Amino Acid Amide Nucleophile: Synthesis of Constrained H-Phe-Phe-NH2 Analogues

Skogh, Anna; Fransson, Rebecca; Sköld, Christian; Larhed, Mats et al.

Part of Journal of Organic Chemistry, p. 12251-12256, 2013

• DOI for Aminocarbonylation of 4-Iodo-1H-imidazoles with an Amino Acid Amide Nucleophile: Synthesis of Constrained H-Phe-Phe-NH2 Analogues

Constrained H-Phe-Phe-NH₂ Analogues With High Affinity to the Substance P 1-7 Binding Site and With Improved Metabolic Stability and Cell Permeability

Fransson, Rebecca; Sköld, Christian; Kratz, Jadel M; Svensson, Richard et al.

Part of Journal of Medicinal Chemistry, p. 4953-4965, 2013

• DOI for Constrained H-Phe-Phe-NH₂ Analogues With High Affinity to the Substance P 1-7 Binding Site and With Improved Metabolic Stability and Cell Permeability

Synthesis of Novel Aryl and Heteroaryl Acyl Sulfonimidamides via Pd-Catalyzed Carbonylation Using a Nongaseous Precursor

Borhade, Sanjay R.; Sandström, Anja; Arvidsson, Per I.

Part of Organic Letters, p. 1056-1059, 2013

• DOI for Synthesis of Novel Aryl and Heteroaryl Acyl Sulfonimidamides via Pd-Catalyzed Carbonylation Using a Nongaseous Precursor

Synthesis of functionalized furopyrazines as restricted dipeptidomimetics

Claerhout, Stijn; Sharma, Sweta; Sköld, Christian; Cavaluzzo, Claudia et al.

Part of Tetrahedron, p. 3019-3029, 2012

• DOI for Synthesis of functionalized furopyrazines as restricted dipeptidomimetics

The dipeptide Phe-Phe amide attenuates signs of hyperalgesia, allodynia and nociception in diabetic mice using a mechanism involving the sigma receptor system

Ohsawa, Masahiro; Carlsson, Anna; Asato, Megumi; Koizumi, Takayuki et al.

Part of Molecular Pain, p. 85, 2011

• DOI for The dipeptide Phe-Phe amide attenuates signs of hyperalgesia, allodynia and nociception in diabetic mice using a mechanism involving the sigma receptor system
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P2-P1 ' macrocyclization of P2 phenylglycine based HCV NS3 protease inhibitors using ring-closing metathesis

Lampa, Anna; Ehrenberg, Angelica E.; Vema, Aparna; Åkerblom, Eva et al.

Part of Bioorganic & Medicinal Chemistry, p. 4917-4927, 2011

• DOI for P2-P1 ' macrocyclization of P2 phenylglycine based HCV NS3 protease inhibitors using ring-closing metathesis

The effect of substance P1-7 amide on nociceptive threshold in diabetic mice

Ohsawa, Masahiro; Carlsson, Anna; Asato, Megumi; Koizumi, Takayuki et al.

Part of Peptides, p. 93-98, 2011

• DOI for The effect of substance P1-7 amide on nociceptive threshold in diabetic mice

Discovery of Achiral Inhibitors of the Hepatitis C Virus NS3 Protease based on 2(1H)-pyrazinones

Örtqvist, Pernilla; Gising, Johan; Ehrenberg, Angelica; Vema, Aparna et al.

Part of Bioorganic & Medicinal Chemistry, p. 6512-6525, 2010

• DOI for Discovery of Achiral Inhibitors of the Hepatitis C Virus NS3 Protease based on 2(1H)-pyrazinones

Hepatitis C protease inhibitors based on 2(1H)-pyrazinones

Gising, Johan; Belfrage, Anna Karin; Örtqvist, Pernilla; Larhed, Mats et al.

Part of Abstracts of Papers of the American Chemical Society, 2010

Structure-activity relationships of HCV NS3 protease inhibitors evaluated on the drug-resistant variants A156T and D168V

Örtqvist, Pernilla; Vema, Aparna; Ehrenberg, Angelica E; Dahl, Göran et al.

Part of Antiviral Therapy, p. 841-852, 2010

• DOI for Structure-activity relationships of HCV NS3 protease inhibitors evaluated on the drug-resistant variants A156T and D168V

Improved P2 phenylglycine-based hepatitis C virus NS3 protease inhibitors with alkenylic prime-side substituents

Lampa, Anna; Ehrenberg, Angelica E.; Gustafsson, Sofia S.; Vema, Aparna et al.

Part of Bioorganic & Medicinal Chemistry, p. 5413-5424, 2010

• DOI for Improved P2 phenylglycine-based hepatitis C virus NS3 protease inhibitors with alkenylic prime-side substituents

Discovery of Dipeptides with High Affinity to the Specific Binding Site for Substance P1-7

Fransson, Rebecca; Botros, Milad; Sköld, Christian; Nyberg, Fred et al.

Part of Journal of Medicinal Chemistry, p. 2383-2389, 2010

• DOI for Discovery of Dipeptides with High Affinity to the Specific Binding Site for Substance P1-7

A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

Gising, Johan; Örtqvist, Pernilla; Sandström, Anja; Larhed, Mats

Part of Organic and biomolecular chemistry, p. 2809-2815, 2009

• DOI for A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

Hepatitis C virus NS3 protease inhibitors: large, flexible molecules of peptide origin show satisfactory permeability across Caco-2 cells

Bergström, Christel A S; Bolin, Sara; Artursson, Per; Rönn, Robert et al.

Part of European Journal of Pharmaceutical Sciences, p. 556-563, 2009

• DOI for Hepatitis C virus NS3 protease inhibitors: large, flexible molecules of peptide origin show satisfactory permeability across Caco-2 cells

The C-terminal amidated analogue of the Substance P (SP) fragment SP (1-7) attenuates the expression of naloxone- precipitated withdrawal in morphine dependent rats

Zhou, Qin; Carlsson, Anna; Botros, Milad; Fransson, Rebecca et al.

Part of Peptides, p. 2418-2422, 2009

• DOI for The C-terminal amidated analogue of the Substance P (SP) fragment SP (1-7) attenuates the expression of naloxone- precipitated withdrawal in morphine dependent rats

Small peptides mimicking substance P (1-7) and encompassing a C-terminal amide functionality

Fransson, Rebecca; Botros, Milad; Nyberg, Fred; Lindeberg, Gunnar et al.

Part of Neuropeptides, p. 31-37, 2008

• DOI for Small peptides mimicking substance P (1-7) and encompassing a C-terminal amide functionality

β-Amino acid substitutions and structure-based CoMFA modeling of hepatitis C virus NS3 protease inhibitors

Nurbo, Johanna; Peterson, Shane D.; Dahl, Göran; Danielson, U. Helena et al.

Part of Bioorganic & Medicinal Chemistry, p. 5590-5605, 2008

• DOI for β-Amino acid substitutions and structure-based CoMFA modeling of hepatitis C virus NS3 protease inhibitors

Hepatitis C Virus NS3 Protease Inhibitors Comprising a Novel Aromatic P1 Moiety

Rönn, Robert; Lampa, Anna; Peterson, Shane D.; Gossas, Thomas et al.

Part of Bioorganic & Medicinal Chemistry, p. 2955-2967, 2008

• DOI for Hepatitis C Virus NS3 Protease Inhibitors Comprising a Novel Aromatic P1 Moiety

Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors

Rönn, Robert; Gossas, Thomas; Sabnis, Yogesh A.; Daoud, Hanna et al.

Part of Bioorganic & Medicinal Chemistry, p. 4057-4068, 2007

• DOI for Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors

Mechanistic studies of electrophilic protease inhibitors of full length hepatic C virus (HCV) NS3

Poliakov, Anton; Sandström, Anja; Åkerblom, Eva; Danielson, U. Helena

Part of Journal of enzyme inhibition and medicinal chemistry (Print), p. 191-199, 2007

• DOI for Mechanistic studies of electrophilic protease inhibitors of full length hepatic C virus (HCV) NS3

Phenylglycine as a Novel P2 Scaffold in Hepatitis C Virus NS3 Protease Inhibitors

Örtqvist, Pernilla; Peterson, Shane D.; Åkerblom, Eva; Gossas, Thomas et al.

Part of Bioorganic & Medicinal Chemistry, p. 1448-1474, 2007

• DOI for Phenylglycine as a Novel P2 Scaffold in Hepatitis C Virus NS3 Protease Inhibitors

Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3

Dahl, Göran; Sandström, Anja; Åkerblom, Eva; Danielson, U. Helena

Part of The FEBS Journal, p. 5979-5986, 2007

• DOI for Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3

Resistance profiling of hepatitis C virus protease inhibitors using full-length NS3

Dahl, Göran; Sandström, Anja; Åkerblom, Eva; Danielson, U. Helena

Part of Antiviral Therapy, p. 733-740, 2007

Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3

Rönn, Robert; Sabnis, Yogesh A; Gossas, Thomas; Åkerblom, Eva et al.

Part of Bioorganic & Medicinal Chemistry, p. 544-559, 2006

• DOI for Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3

Structure-activity relationships for the selectivity of hepatitis C virus NS3 protease inhibitors

Poliakov, Anton; Johansson, Anja; Åkerblom, Eva; Oscarsson, Karin et al.

Part of Biochimica et Biophysica Acta, p. 51-59, 2004

• DOI for Structure-activity relationships for the selectivity of hepatitis C virus NS3 protease inhibitors

Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-length NS3 (protease-helicase/NTPase): a comparative study of different C-terminals

Johansson, Anja; Poliakov, Anton; Åkerblom, Eva; Wiklund, Karin et al.

Part of Bioorganic & Medicinal Chemistry, p. 2551-2568, 2003

• DOI for Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-length NS3 (protease-helicase/NTPase): a comparative study of different C-terminals

Tetrapeptides as potent protease inhibitors of Hepatitis C Virus full-length NS3 (protease-helicase/NTPase)

Johansson, Anja; Poliakov, Anton; Åkerblom, Eva; Lindeberg, Gunnar et al.

Part of Bioorganic & Medicinal Chemistry, p. 3915-22, 2002

• DOI for Tetrapeptides as potent protease inhibitors of Hepatitis C Virus full-length NS3 (protease-helicase/NTPase)

Vinyl sulfide cyclized analogues of angiotensin II with high affinity and full agonist activity at the AT(1) receptor

Johannesson, Petra; Lindeberg, Gunnar; Johansson, Anja; Nikiforovich, Gregory V et al.

Part of Journal of Medicinal Chemistry, p. 1767-1777, 2002

• DOI for Vinyl sulfide cyclized analogues of angiotensin II with high affinity and full agonist activity at the AT(1) receptor

Inhibition of hepatitis C virus NS3 protease activity by product-based peptides is dependent on helicase domain

Johansson, Anja; Hubatsch, Ina; Åkerblom, Eva; Lindeberg, Gunnar et al.

Part of Bioorganic & Medicinal Chemistry Letters, p. 203-206, 2001

• DOI for Inhibition of hepatitis C virus NS3 protease activity by product-based peptides is dependent on helicase domain

An Improved Procedure for N- to C-Directed (Inverse) Solid-Phase Peptide Synthesis

Johansson, Anja; Åkerblom, Eva; Ersmark, Karolina; Lindeberg, Gunnar et al.

Part of Journal of combinatorial chemistry, p. 496-507, 2000

• DOI for An Improved Procedure for N- to C-Directed (Inverse) Solid-Phase Peptide Synthesis

From the Anti-Nociceptive Substance P Metabolite Substance P (1-7) to Small Peptidomimetics

Hallberg, Mathias; Sandström, Anja

Part of Current protein and peptide science, p. 1038-1048, 2018

• DOI for From the Anti-Nociceptive Substance P Metabolite Substance P (1-7) to Small Peptidomimetics

New developments in the discovery of agents to treat hepatitis C

Rönn, Robert; Sandström, Anja

Part of Current Topics in Medicinal Chemistry, p. 533-562, 2008

• DOI for New developments in the discovery of agents to treat hepatitis C

Use of Peptides as Drug Leads: A Case Story on the Development of Dipeptides Corresponding to the Heptapeptide Substance P(1-7), with Intriguing Effects on Neuropathic Pain

Fransson, Rebecca; Sandström, Anja

Part of In Neuropeptides in Neuroprotection and Neuroregeneration., p. 253-270, Taylor & Francis Group, 2012

• DOI for Use of Peptides as Drug Leads: A Case Story on the Development of Dipeptides Corresponding to the Heptapeptide Substance P(1-7), with Intriguing Effects on Neuropathic Pain

Design and Synthesis of Hepatitis C Virus NS3 Protease Inhibitors

Johansson, Anja

2003

• Download full text (pdf) of Design and Synthesis of Hepatitis C Virus NS3 Protease Inhibitors

Investigation of beta-amino acids as building blocks in hepatitis c virus NS3 protease inhibitors

Nurbo, Johanna; Dahl, G; Danielson, U Helena; Sandström, Anja

2007

Novel peptidomimetic HCV NS3 protease inhibitors spanning the P2-P1´ region

Lampa, Anna; Bergman, Sara; Svahn Gustafsson, Sofia; Alogheli, Hiba et al.

Design of a Stapled Peptide Targeting KLHL20^Kelch: A Computational and Biosensor-based Approach

Myers, Nadine; Cadot, Marie Elodie Helene; Varga, Julia; Diallo, Marcel et al.