Christer Betsholtz

FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis

Sountoulidis, Alexandros; Theelke, Jonas; Liontos, Andreas; Firsova, Alexandra B. et al.

Part of Nature Communications, 2026

• DOI for FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis
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Loss of meningeal lymphatic endothelial cells results in formation of a newly forming vascular network with scavenging function

Uphoff, Katharina; Van Impel, Andreas; Muhl, Lars; Stehling, Martin et al.

Part of Development, 2026

• DOI for Loss of meningeal lymphatic endothelial cells results in formation of a newly forming vascular network with scavenging function
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A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver

Pietilä, Riikka; Genové, Guillem; Mocci, Giuseppe; Miao, Yuyang et al.

Part of EMBO Reports, p. 5326-5359, 2025

• DOI for A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
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GPIHBP1, lipoprotein lipase, and triglyceride-rich lipoproteins in capillaries of the choroid plexus and circumventricular organs.

Song, Wenxin; Hung, Madison; Kozlov, Ellen; Hung, Megan et al.

Part of Journal of Clinical Investigation, 2025

• DOI for GPIHBP1, lipoprotein lipase, and triglyceride-rich lipoproteins in capillaries of the choroid plexus and circumventricular organs.

Distinguishing subtypes of endothelial cells in the mouse aorta

He, Liqun; Pietilä, Riikka; Miao, Yuyang; Vázquez, Elisa et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2025

• DOI for Distinguishing subtypes of endothelial cells in the mouse aorta
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FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis

Sountoulidis, Alexandros; Theelke, Jonas; Liontos, Andreas; Firsova, Alexandra B. et al.

Part of Nature Communications, 2026

• DOI for FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis
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Loss of meningeal lymphatic endothelial cells results in formation of a newly forming vascular network with scavenging function

Uphoff, Katharina; Van Impel, Andreas; Muhl, Lars; Stehling, Martin et al.

Part of Development, 2026

• DOI for Loss of meningeal lymphatic endothelial cells results in formation of a newly forming vascular network with scavenging function
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A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver

Pietilä, Riikka; Genové, Guillem; Mocci, Giuseppe; Miao, Yuyang et al.

Part of EMBO Reports, p. 5326-5359, 2025

• DOI for A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
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GPIHBP1, lipoprotein lipase, and triglyceride-rich lipoproteins in capillaries of the choroid plexus and circumventricular organs.

Song, Wenxin; Hung, Madison; Kozlov, Ellen; Hung, Megan et al.

Part of Journal of Clinical Investigation, 2025

• DOI for GPIHBP1, lipoprotein lipase, and triglyceride-rich lipoproteins in capillaries of the choroid plexus and circumventricular organs.

Distinguishing subtypes of endothelial cells in the mouse aorta

He, Liqun; Pietilä, Riikka; Miao, Yuyang; Vázquez, Elisa et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2025

• DOI for Distinguishing subtypes of endothelial cells in the mouse aorta
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TIE2 activation by antibody-clustered endogenous angiopoietin-2 prevents capillary loss and fibrosis in experimental kidney disease

Pietilä, Riikka; Marks-Hultström, Amanda; He, Liqun; Nanavazadeh, Sami et al.

Part of Journal of Clinical Investigation, 2025

• DOI for TIE2 activation by antibody-clustered endogenous angiopoietin-2 prevents capillary loss and fibrosis in experimental kidney disease
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Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques

Sukhavasi, Katyayani; Mocci, Giuseppe; Ma, Lijiang; Hodonsky, Chani J. et al.

Part of Nature Cardiovascular Research, p. 412-432, 2025

• DOI for Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques
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Brain macrophages and pial fibroblasts promote inflammation in a hypomyelination model

Okuno, Noriko; Yamamoto, Seiji; Hamashima, Takeru; Dang, Tung Son et al.

Part of Acta neuropathologica communications, 2025

• DOI for Brain macrophages and pial fibroblasts promote inflammation in a hypomyelination model
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Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis

Kondrychyn, Igor; He, Liqun; Wint, Haymar; Betsholtz, Christer et al.

Part of eLIFE, 2025

• DOI for Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis
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Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage

Vázquez-Liébanas, Elisa; Mocci, Giuseppe; Li, Weihan; Laviña, Bàrbara et al.

Part of Cell Reports, 2024

• DOI for Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage
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Distinct strategies for intravascular triglyceride metabolism in hearts of mammals and lower vertebrate species

Nguyen, Le Phuong; Song, Wenxin; Yang, Ye; Tran, Anh P. et al.

Part of JCI Insight, 2024

• DOI for Distinct strategies for intravascular triglyceride metabolism in hearts of mammals and lower vertebrate species
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Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis

Mocci, Giuseppe; Sukhavasi, Katyayani; Ord, Tiit; Bankier, Sean et al.

Part of Circulation Research, p. 1405-1423, 2024

• DOI for Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis
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Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner

ElBeck, Zaher; Hossain, Mohammad Bakhtiar; Siga, Humam; Oskolkov, Nikolay et al.

Part of Nature Communications, 2024

• DOI for Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner
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Insights into mechanisms and therapeutic avenues for primary familial brain calcification

Betsholtz, Christer

Part of Neuron, p. 3223-3225, 2024

• DOI for Insights into mechanisms and therapeutic avenues for primary familial brain calcification

Single-cell dissection of the human blood-brain barrier and glioma blood-tumor barrier

Xie, Yuan; Yang, Fan; He, Liqun; Huang, Hua et al.

Part of Neuron, 2024

• DOI for Single-cell dissection of the human blood-brain barrier and glioma blood-tumor barrier

Adipose stem cells are sexually dimorphic cells with dual roles as preadipocytes and resident fibroblasts

Uhrbom, Martin; Muhl, Lars; Genove, Guillem; Liu, Jianping et al.

Part of Nature Communications, 2024

• DOI for Adipose stem cells are sexually dimorphic cells with dual roles as preadipocytes and resident fibroblasts
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Commentary on "Structural characterization of SLYM - a 4th meningeal membrane"

Siegenthaler, Julie; Betsholtz, Christer

Part of Fluids and Barriers of the CNS, 2024

• DOI for Commentary on "Structural characterization of SLYM - a 4th meningeal membrane"
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Rapid and robust isolation of microglia and vascular cells from brain subregions for integrative single-cell analyses

Preka, Efthalia; Romero, Alejandro Lastra; Sun, Ying; Vilalta, Yara Onetti et al.

Part of Heliyon, 2024

• DOI for Rapid and robust isolation of microglia and vascular cells from brain subregions for integrative single-cell analyses
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A brain-specific angiogenic mechanism enabled by tip cell specialization

Schevenels, Giel; Cabochette, Pauline; America, Michelle; Vandenborne, Arnaud et al.

Part of Nature, p. 863-871, 2024

• DOI for A brain-specific angiogenic mechanism enabled by tip cell specialization
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Renal Endothelial Single-Cell Transcriptomics Reveals Spatiotemporal Regulation and Divergent Roles of Differential Gene Transcription and Alternative Splicing in Murine Diabetic Nephropathy

Zhou, Alex-Xianghua; Jeansson, Marie; He, Liqun; Wigge, Leif et al.

Part of International Journal of Molecular Sciences, 2024

• DOI for Renal Endothelial Single-Cell Transcriptomics Reveals Spatiotemporal Regulation and Divergent Roles of Differential Gene Transcription and Alternative Splicing in Murine Diabetic Nephropathy
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The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier

Kurtyka, Magdalena; Wessely, Frank; Bau, Sarah; Ifie, Eseoghene et al.

Part of European Journal of Cell Biology, 2024

• DOI for The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier
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Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Gupta, Rajesh Kumar; Niklasson, Mia; Bergström, Tobias; Segerman, Anna et al.

Part of Scientific Reports, 2024

• DOI for Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain
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A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature

Bjornholm, Katrine Dahl; Del Gaudio, Francesca; Li, Hao; Li, Weihan et al.

Part of Cell Reports Methods, 2023

• DOI for A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature

The role of dendrin in IgA nephropathy

Levin, Anna; Schwarz, Angelina; Hulkko, Jenny; He, Liqun et al.

Part of Nephrology, Dialysis and Transplantation, p. 311-321, 2023

• DOI for The role of dendrin in IgA nephropathy
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Left ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart

Del Gaudio, Francesca; Liu, Dongli; Andaloussi Mäe, Maarja; Braune, Eike-Benjamin et al.

Part of Scientific Reports, 2023

• DOI for Left ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart
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Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation

Petkova, Milena; Kraft, Marle; Stritt, Simon; Martinez-Corral, Ines et al.

Part of Journal of Experimental Medicine, 2023

• DOI for Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation
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Molecular anatomy of adult mouse leptomeninges

Pietilä, Riikka; Del Gaudio, Francesca; He, Liqun; Vázquez-Liébanas, Elisa et al.

Part of Neuron, 2023

• DOI for Molecular anatomy of adult mouse leptomeninges
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VE-cadherin in arachnoid and pia mater cells serves as a suitable landmark for in vivo imaging of CNS immune surveillance and inflammation

Mapunda, Josephine A.; Pareja, Javier; Vladymyrov, Mykhailo; Bouillet, Elisa et al.

Part of Nature Communications, 2023

• DOI for VE-cadherin in arachnoid and pia mater cells serves as a suitable landmark for in vivo imaging of CNS immune surveillance and inflammation
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Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development

Vazquez-Liebanas, Elisa; Nahar, Khayrun; Bertuzzi, Giacomo; Keller, Annika et al.

Part of Journal of Cerebral Blood Flow and Metabolism, p. 264-279, 2022

• DOI for Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development
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Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients

Hultström, Michael; Fromell, Karin; Larsson, Anders; Persson, Barbro et al.

Part of Biomedicines, 2022

• DOI for Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients
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PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny

da Bandeira, Diana Sa; Kilpatrick, Alastair Morris; Marques, Madalena; Gomez-Salazar, Mario et al.

Part of Cell Reports, 2022

• DOI for PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny
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Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner

Richards, Mark; Nwadozi, Emmanuel; Pal, Sagnik; Martinsson, Pernilla et al.

Part of eLIFE, 2022

• DOI for Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner
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Elevated Angiopoietin-2 inhibits thrombomodulin-mediated anticoagulation in critically ill COVID-19 patients

Hultström, Michael; Fromell, Karin; Larsson, Anders; Quaggin, Susan E et al.

Part of Biomedicines, p. 1333-27, 2022

• DOI for Elevated Angiopoietin-2 inhibits thrombomodulin-mediated anticoagulation in critically ill COVID-19 patients
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Molecular insights into the early stage of glomerular injury in IgA nephropathy using single-cell RNA sequencing

Zambrano, Sonia; He, Liqun; Kano, Toshiki; Sun, Ying et al.

Part of Kidney International, p. 752-765, 2022

• DOI for Molecular insights into the early stage of glomerular injury in IgA nephropathy using single-cell RNA sequencing

Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium

Shoda, Jumpei; Tanaka, Shigeru; Etori, Keishi; Hattori, Koto et al.

Part of Arthritis Research & Therapy, 2022

• DOI for Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium
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Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFR alpha signalling in cerebellar development

Gillnäs, Sara; Gallini, Radiosa; He, Liqun; Betsholtz, Christer et al.

Part of BIOLOGY OPEN, 2022

• DOI for Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFR alpha signalling in cerebellar development
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A single-cell transcriptomic inventory of murine smooth muscle cells

Muhl, Lars; Mocci, Giuseppe; Pietilä, Riikka; Liu, Jianping et al.

Part of Developmental Cell, p. 2426-+, 2022

• DOI for A single-cell transcriptomic inventory of murine smooth muscle cells
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Cellular Origin of Sporadic CCMs

Betsholtz, Christer; Gängel, Konstantin; Mäkinen, Taija

Part of New England Journal of Medicine, p. 1291-1291, 2022

• DOI for Cellular Origin of Sporadic CCMs

Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow

Orlich, Michael M.; Dieguez-Hurtado, Rodrigo; Muehlfriedel, Regine; Sothilingam, Vithiyanjali et al.

Part of Circulation Research, p. 308-327, 2022

• DOI for Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow
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An overlooked subset of Cx3cr1(wt/wt) microglia in the Cx3cr1(CreER-Eyfp/wt) mouse has a repopulation advantage over Cx3cr1(CreER-Eyfp/wt) microglia following microglial depletion

Zhou, Kai; Han, Jinming; Lund, Harald; Boggavarapu, Nageswara Rao et al.

Part of Journal of Neuroinflammation, 2022

• DOI for An overlooked subset of Cx3cr1(wt/wt) microglia in the Cx3cr1(CreER-Eyfp/wt) mouse has a repopulation advantage over Cx3cr1(CreER-Eyfp/wt) microglia following microglial depletion
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Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells

Peng, Di; Ando, Koji; Hussmann, Melina; Gloger, Marleen et al.

Part of eLIFE, 2022

• DOI for Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells
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Microvascular stabilization via blood-brain barrier regulation prevents seizure activity

Greene, Chris; Hanley, Nicole; Reschke, Cristina R.; Reddy, Avril et al.

Part of Nature Communications, 2022

• DOI for Microvascular stabilization via blood-brain barrier regulation prevents seizure activity
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The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research

Muhl, Lars; He, Liqun; Sun, Ying; Andaloussi Mäe, Maarja et al.

Part of Stem Cell Reports, p. 1089-1104, 2022

• DOI for The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research

ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

Bernier-Latmani, Jeremiah; Mauri, Cristina; Marcone, Rachel; Renevey, Francois et al.

Part of Nature Communications, 2022

• DOI for ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels
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Specification of CNS macrophage subsets occurs postnatally in defined niches

Masuda, Takahiro; Amann, Lukas; Monaco, Gianni; Sankowski, Roman et al.

Part of Nature, p. 740-+, 2022

• DOI for Specification of CNS macrophage subsets occurs postnatally in defined niches

KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling

Ando, Koji; Tong, Lei; Peng, Di; Vazquez-Liebanas, Elisa et al.

Part of Developmental Cell, p. 1383-13990000000, 2022

• DOI for KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling

Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss

Mäe, Maarja Andaloussi; He, Liqun; Nordling, Sofia; Vazquez-Liebanas, Elisa et al.

Part of Circulation Research, 2021

• DOI for Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss

Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes

He, Bing; Chen, Ping; Zambrano, Sonia; Dabaghie, Dina et al.

Part of Nature Communications, 2021

• DOI for Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes
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Lack of Evidence of Angiotensin-Converting Enzyme 2 Expression and Replicative Infection by SARS-CoV-2 in Human Endothelial Cells

McCracken, Ian R.; Saginc, Gaye; He, Liqun; Huseynov, Alik et al.

Part of Circulation, p. 865-868, 2021

• DOI for Lack of Evidence of Angiotensin-Converting Enzyme 2 Expression and Replicative Infection by SARS-CoV-2 in Human Endothelial Cells

VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration

Räsänen, Markus; Sultan, Ibrahim; Paech, Jennifer; Hemanthakumar, Karthik Amudhala et al.

Part of Circulation, p. 65-77, 2021

• DOI for VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration
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A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis

Tillie, Renee J. H. A.; Theelen, Thomas L.; van Kuijk, Kim; Temmerman, Lieve et al.

Part of Cells, p. 1746, 2021

• DOI for A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis
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Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice

Nguyen, Quang Linh; Okuno, Noriko; Hamashima, Takeru; Dang, Son Tung et al.

Part of Angiogenesis, p. 35-46, 2021

• DOI for Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice

Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development

Ando, Koji; Shih, Yu-Huan; Ebarasi, Lwaki; Grosse, Ann et al.

Part of Developmental Biology, p. 11-22, 2021

• DOI for Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development

Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing

Xie, Yuan; He, Liqun; Lugano, Roberta; Zhang, Yanyu et al.

Part of JCI Insight, 2021

• DOI for Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing
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ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.

Huang, Hua; Georganaki, Maria; Conze, Lei Liu; Laviña, Bàrbara et al.

Part of Neuro-Oncology, p. 398-411, 2021

• DOI for ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
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A human cell type similar to murine central nervous system perivascular fibroblasts

Liu, Jianping; He, Liqun; Muhl, Lars; Mocci, Giuseppe et al.

Part of Experimental Cell Research, 2021

• DOI for A human cell type similar to murine central nervous system perivascular fibroblasts
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A novel podocyte protein, R3h domain containing-like, inhibits TGF-β-induced p38 MAPK and regulates the structure of podocytes and glomerular basement membrane

Ishikawa, Takahiro; Takemoto, Minoru; Akimoto, Yoshihiro; Takada-Watanabe, Aki et al.

Part of Journal of Molecular Medicine, p. 859-876, 2021

• DOI for A novel podocyte protein, R3h domain containing-like, inhibits TGF-β-induced p38 MAPK and regulates the structure of podocytes and glomerular basement membrane

The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression

Wu, Dan; Wang, Sailan; Oliveira, Daniel V.; Del Gaudio, Francesca et al.

Part of Disease Models and Mechanisms, 2021

• DOI for The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression
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Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain

Osman, Ahmed M.; Sun, Ying; Burns, Terry C.; He, Liqun et al.

Part of Cell Reports, 2020

• DOI for Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain
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Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier

Santander, Nicolas; Lizama, Carlos O.; Meky, Eman; McKinsey, Gabriel L. et al.

Part of Journal of Clinical Investigation, p. 4055-4068, 2020

• DOI for Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier

Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis

Wang, Guangxia; Muhl, Lars; Padberg, Yvonne; Dupont, Laura et al.

Part of Nature Communications, 2020

• DOI for Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis
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Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines

Alvarez, Alberto; Martinez-Corral, Ines; Daubel, Nina; Betsholtz, Christer et al.

Part of Transgenic research, p. 53-68, 2020

• DOI for Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines
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Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis

He, Qi; Li, Xiujuan; He, Liqun; Li, Yousheng et al.

Part of International Journal of Cancer, p. 2634-2644, 2020

• DOI for Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis
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Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification

Nahar, Khayrun; Lebouvier, Thibaud; Andaloussi Mäe, Maarja; Konzer, Anne et al.

Part of Brain Pathology, p. 446-464, 2020

• DOI for Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification
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Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Zhang, Yanyu; Cedervall, Jessica; Hamidi, Anahita; Herre, Melanie et al.

Part of Cancer Research, p. 3345-3358, 2020

• DOI for Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung

Gouveia, Maria Leonor Seguardo; Kraut, Simone; Hadzic, Stefan; Vazquez-Liebanas, Elisa et al.

Part of American Journal of Physiology - Lung cellular and Molecular Physiology, 2020

• DOI for Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung

Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization

Yanagida, Keisuke; Engelbrecht, Eric; Niaudet, Colin; Jung, Bongnam et al.

Part of Developmental Cell, p. 779-+, 2020

• DOI for Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization

Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

Engelbrecht, Eric; Levesque, Michel; He, Liqun; Vanlandewijck, Michael et al.

Part of eLIFE, 2020

• DOI for Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
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PDGF-B Is Required for Development of the Glymphatic System

Munk, Anne Sofie; Wang, Wei; Bechet, Nicholas Burdon; Eltanahy, Ahmed M. et al.

Part of Cell Reports, p. 2955-+, 2019

• DOI for PDGF-B Is Required for Development of the Glymphatic System
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Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFR alpha in Adult Brain

Dang, Thanh Chung; Ishii, Yoko; Nguyen, Van De; Yamamoto, Seiji et al.

Part of Cell Reports, p. 1073-1089, 2019

• DOI for Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFR alpha in Adult Brain
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Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits

Glicksberg, Benjamin S.; Amadori, Letizia; Akers, Nicholas K.; Sukhavasi, Katyayani et al.

Part of BMC Medical Genomics, 2019

• DOI for Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits
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Peri-arterial specification of vascular mural cells from naive mesenchyme requires Notch signaling

Ando, Koji; Wang, Weili; Peng, Di; Chiba, Ayano et al.

Part of Development, 2019

• DOI for Peri-arterial specification of vascular mural cells from naive mesenchyme requires Notch signaling

Claudin-3-deficient C57BL/6J mice display intact brain barriers

Dias, Mariana Castro; Coisne, Caroline; Lazarevic, Ivana; Baden, Pascale et al.

Part of Scientific Reports, 2019

• DOI for Claudin-3-deficient C57BL/6J mice display intact brain barriers
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Adgrf5 contributes to patterning of the endothelial deep layer in retina

Niaudet, Colin; Petkova, Milena; Jung, Bongnam; Lu, S. et al.

Part of Angiogenesis, p. 491-505, 2019

• DOI for Adgrf5 contributes to patterning of the endothelial deep layer in retina
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R3hdml regulates satellite cell proliferation and differentiation

Sakamoto, Kenichi; Furuichi, Yasuro; Yamamoto, Masashi; Takahashi, Megumi et al.

Part of EMBO Reports, 2019

• DOI for R3hdml regulates satellite cell proliferation and differentiation

GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients

Hu, Xuchen; Matsumoto, Ken; Jung, Rachel S.; Weston, Thomas A. et al.

Part of eLIFE, 2019

• DOI for GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients
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CDC42 deletion elicits cerebral vascular malformations via increased MEKK3-dependent KLF4 expression

Castro, Marco; Laviña, Bàrbara; Ando, Koji; Alvarez-Aznar, Alberto et al.

Part of Circulation Research, p. 1240-1252, 2019

• DOI for CDC42 deletion elicits cerebral vascular malformations via increased MEKK3-dependent KLF4 expression

Sprouting and anastomosis in the Drosophila trachea and the vertebrate vasculature: Similarities and differences in cell behaviour

Kotini, Maria Paraskevi; Mäe, Maarja Andaloussi; Belting, Heinz-Georg; Betsholtz, Christer et al.

Part of Vascular pharmacology, p. 8-16, 2019

• DOI for Sprouting and anastomosis in the Drosophila trachea and the vertebrate vasculature: Similarities and differences in cell behaviour

Inverse correlation between vascular endothelial growth factor back-filtration and capillary filtration pressures

Kuppe, Christoph; Rohlfs, Wilko; Grepl, Martin; Schulte, Kevin et al.

Part of Nephrology, Dialysis and Transplantation, p. 1514-1525, 2018

• DOI for Inverse correlation between vascular endothelial growth factor back-filtration and capillary filtration pressures

Global analysis of A-to-I RNA editing reveals association with common disease variants

Franzen, Oscar; Ermel, Raili; Sukhavasi, Katyayani; Jain, Rajeev et al.

Part of PeerJ, 2018

• DOI for Global analysis of A-to-I RNA editing reveals association with common disease variants
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Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events

Honkura, Naoki; Richards, Mark; Laviña, Bàrbara; Sainz-Jaspeado, Miguel et al.

Part of Nature Communications, 2018

• DOI for Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events
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Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier

Mäe, Maarja Andaloussi; Li, Tian; Bertuzzi, Giacomo; Raschperger, Elisabeth et al.

Part of Scientific Reports, 2018

• DOI for Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier
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Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

Laviña, Bàrbara; Castro, Marco; Niaudet, Colin; Cruys, Bert et al.

Part of Development, 2018

• DOI for Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice

Loganathan, Krishnapriya; Salem Said, Ebtisam; Winterrowd, Emily; Orebrand, Martina et al.

Part of PLOS ONE, 2018

• DOI for Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice
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A molecular atlas of cell types and zonation in the brain vasculature

Vanlandewijck, Michael; He, Liqun; Mäe, Maarja Andaloussi; Andrae, Johanna et al.

Part of Nature, p. 475-480, 2018

• DOI for A molecular atlas of cell types and zonation in the brain vasculature

Rate of Small-Molecular Drug Transport Across the Blood-Brain Barrier in a Pericyte-Deficient State

Mihajlica, Nebojsa; Betsholtz, Christer; Hammarlund-Udenaes, Margareta

Part of European Journal of Pharmaceutical Sciences, p. 182-187, 2018

• DOI for Rate of Small-Molecular Drug Transport Across the Blood-Brain Barrier in a Pericyte-Deficient State

Multiple roles of lymphatic vessels in peripheral lymph node development

Bovay, Esther; Sabine, Amelie; Prat-Luri, Borja; Kim, Sudong et al.

Part of Journal of Experimental Medicine, p. 2760-2777, 2018

• DOI for Multiple roles of lymphatic vessels in peripheral lymph node development

Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

He, Liqun; Vanlandewijck, Michael; Mäe, Maarja Andaloussi; Andrae, Johanna et al.

Part of Scientific Data, 2018

• DOI for Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types
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Pharmacokinetics of Pericyte Involvement in Small-Molecular Drug Transport Across the Blood-Brain Barrier

Mihajlica, Nebojsa; Betsholtz, Christer; Hammarlund-Udenaes, Margareta

Part of European Journal of Pharmaceutical Sciences, p. 77-84, 2018

• DOI for Pharmacokinetics of Pericyte Involvement in Small-Molecular Drug Transport Across the Blood-Brain Barrier

PDGF-A signaling is required for secondary alveolar septation and controls epithelial proliferation in the developing lung

Gouveia, Leonor; Betsholtz, Christer; Andrae, Johanna

Part of Development, 2018

• DOI for PDGF-A signaling is required for secondary alveolar septation and controls epithelial proliferation in the developing lung

Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice

Jung, Bongnam; Arnold, Thomas D.; Raschperger, Elisabeth; Gaengel, Konstantin et al.

Part of Journal of Cerebral Blood Flow and Metabolism, p. 456-468, 2018

• DOI for Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice
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Cell-cell signaling in blood vessel development and function

Betsholtz, Christer

Part of EMBO Molecular Medicine, 2018

• DOI for Cell-cell signaling in blood vessel development and function
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Extracellular retention of PDGF-B directs vascular remodeling in mouse hypoxia-induced pulmonary hypertension

Tannenberg, Philip; Chang, Ya-Ting; Muhl, Lars; Laviña, Bàrbara et al.

Part of American Journal of Physiology - Lung cellular and Molecular Physiology, p. 1593-1605, 2018

• DOI for Extracellular retention of PDGF-B directs vascular remodeling in mouse hypoxia-induced pulmonary hypertension

Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

De La Fuente, Alerie Guzman; Lange, Simona; Silva, Maria Elena; Gonzalez, Ginez A. et al.

Part of Cell Reports, p. 1755-1764, 2017

• DOI for Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy

Liu, Peidi; Lassen, Emelie; Nair, Viji; Berthier, Celine C. et al.

Part of Journal of the American Society of Nephrology, p. 2961-2972, 2017

• DOI for Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy

Expression analysis of platelet-derived growth factor receptor alpha and its ligands in the developing mouse lung

Gouveia, Leonor; Betsholtz, Christer; Andrae, Johanna

Part of Physiological Reports, 2017

• DOI for Expression analysis of platelet-derived growth factor receptor alpha and its ligands in the developing mouse lung
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Claudin 3-Deficient C57BL/6 Mice Display Intact Brain Barriers

Dias, Mariana; Coisne, Caroline; Baden, Pascale; Lazarevic, Ivana et al.

Part of Journal of Vascular Research, p. 63-63, 2017

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

Jones, Gregory T.; Tromp, Gerard; Kuivaniemi, Helena; Gretarsdottir, Solveig et al.

Part of Circulation Research, p. 341-+, 2017

• DOI for Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci
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Pericytes promote the generation of oligodendrocytes during remyelination

Guzman, A.; Lange, S.; Silva, M. E.; Gonzalez, G. A. et al.

Part of Glia, 2017

• DOI for Pericytes promote the generation of oligodendrocytes during remyelination

Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity

Wang, Yixin; Jin, Yi; Mäe, Maarja Andaloussi; Zhang, Yang et al.

Part of Development, p. 3590-3601, 2017

• DOI for Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity

Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling

Jin, Yi; Muhl, Lars; Burmakin, Mikhail; Wang, Yixin et al.

Part of Nature Cell Biology, p. 639-652, 2017

• DOI for Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling

PDGFR alpha signaling is required for alveolar development in the mouse lung

Andrae, Johanna; Betsholtz, Christer; Gouveia, Maria Leonor Seguardo

Part of Mechanisms of Development, 2017

• DOI for PDGFR alpha signaling is required for alveolar development in the mouse lung

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

Webb, Thomas R.; Erdmann, Jeanette; Stirrups, Kathleen E.; Stitziel, Nathan O. et al.

Part of Journal of the American College of Cardiology, p. 823-836, 2017

• DOI for Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease
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The role of microglia in microvascular calcification in the brain

Keller, A.; Zarb, Y.; Johannson, B.; Betsholtz, Christer et al.

Part of Glia, 2017

• DOI for The role of microglia in microvascular calcification in the brain

Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype

Gladh, Hanna; Folestad, Erika Bergsten; Muhl, Lars; Ehnman, Monika et al.

Part of PLOS ONE, 2016

• DOI for Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype
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Transcriptional control of endothelial energy

Betsholtz, Christer

Part of Nature, p. 160-161, 2016

• DOI for Transcriptional control of endothelial energy

Analysis of the brain mural cell transcriptome

He, Liqun; Vanlandewijck, Michael; Raschperger, Elisabeth; Mae, Maarja Andaloussi et al.

Part of Scientific Reports, 2016

• DOI for Analysis of the brain mural cell transcriptome
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Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

Miller, Clint L.; Pjanic, Milos; Wang, Ting; Nguyen, Trieu et al.

Part of Nature Communications, 2016

• DOI for Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
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VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

Li, Xiujuan; Padhan, Narendra; Sjöström, Elisabet O.; Roche, Francis P. et al.

Part of Nature Communications, 2016

• DOI for VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread
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Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier

Villasenor, Roberto; Ozmen, Laurence; Messaddeq, Nadia; Gruninger, Fiona et al.

Part of Scientific Reports, 2016

• DOI for Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier
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A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation

Ishibashi, Ryoichi; Takemoto, Minoru; Akimoto, Yoshihiro; Ishikawa, Takahiro et al.

Part of Scientific Reports, 2016

• DOI for A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation
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Oligodendrocytes follow blood vessel trails in the brain Brain microvasculature is a scaffold for neuroglial migration

Dejana, Elisabetta; Betsholtz, Christer

Part of Science, p. 341-342, 2016

• DOI for Oligodendrocytes follow blood vessel trails in the brain Brain microvasculature is a scaffold for neuroglial migration

Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart

Gallini, Radiosa; Huusko, Jenni; Yla-Herttuala, Seppo; Betsholtz, Christer et al.

Part of PLOS ONE, 2016

• DOI for Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart
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Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis

Rivera-Gonzalez, Guillermo C.; Shook, Brett A.; Andrae, Johanna; Holtrup, Brandon et al.

Part of Cell Stem Cell, p. 738-751, 2016

• DOI for Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis

PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice

Gallini, Radiosa; Lindblom, Per; Bondjers, Cecilia; Betsholtz, Christer et al.

Part of Experimental Cell Research, p. 282-290, 2016

• DOI for PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice
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A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex

Andrae, Johanna; Gouveia, Leonor; Gallini, Radiosa; He, Liqun et al.

Part of BIOLOGY OPEN, p. 461-474, 2016

• DOI for A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex
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Lack Of Pdgf-B Retention Ameliorates Hypoxia-Induced Pulmonary Hypertension

Tannenberg, P.; Folestad, E.; Chang, Y. -T; Gladh, H. et al.

Part of American Journal of Respiratory and Critical Care Medicine, 2016

An Endothelial Gene Signature Score Predicts Poor Outcome in Patients with Endocrine-Treated, Low Genomic Grade Breast Tumors

Tobin, Nicholas P.; Wennmalm, Kristian; Lindstrom, Linda S.; Foukakis, Theodoros et al.

Part of Clinical Cancer Research, p. 2417-2426, 2016

• DOI for An Endothelial Gene Signature Score Predicts Poor Outcome in Patients with Endocrine-Treated, Low Genomic Grade Breast Tumors

Age-dependent modulation of vascular niches for haematopoietic stem cells

Kusumbe, Anjali P.; Ramasamy, Saravana K.; Itkin, Tomer; Mae, Maarja Andaloussi et al.

Part of Nature, p. 380-+, 2016

• DOI for Age-dependent modulation of vascular niches for haematopoietic stem cells

cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels

Stanczuk, Lukas; Martinez-Corral, Ines; Ulvmar, Maria H.; Zhang, Yang et al.

Part of Cell Reports, p. 1708-1721, 2015

• DOI for cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels
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Knockdown of Tmem234 in zebrafish results in proteinuria

Rodriguez, Patricia Q.; Oddsson, Asmundur; Ebarasi, Lwaki; He, Bing et al.

Part of AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2015

• DOI for Knockdown of Tmem234 in zebrafish results in proteinuria

Lipid transport and human brain development

Betsholtz, Christer

Part of Nature Genetics, p. 699-701, 2015

• DOI for Lipid transport and human brain development

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Zeisel, Amit; Munoz-Manchado, Ana B.; Codeluppi, Simone; Lonnerberg, Peter et al.

Part of Science, p. 1138-1142, 2015

• DOI for Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Notch3 Is Necessary for Blood Vessel Integrity in the Central Nervous System

Henshall, Tanya L; Keller, Annika; He, Liqun; Johansson, Bengt R et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 409-420, 2015

• DOI for Notch3 Is Necessary for Blood Vessel Integrity in the Central Nervous System

Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

Niaudet, Colin; Hofmann, Jennifer J.; Mae, Maarja A.; Jung, Bongnam et al.

Part of PLOS ONE, 2015

• DOI for Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification

Vanlandewijck, Michael; Lebouvier, Thibaud; Mae, Maarja Andaloussi; Nahar, Khayrun et al.

Part of PLOS ONE, 2015

• DOI for Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification
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Establishment and Dysfunction of the Blood-Brain Barrier

Zhao, Zhen; Nelson, Amy R.; Betsholtz, Christer; Zlokovic, Berislav V.

Part of Cell, p. 1064-1078, 2015

• DOI for Establishment and Dysfunction of the Blood-Brain Barrier

Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish

Kok, Fatma O.; Shin, Masahiro; Ni, Chih-Wen; Gupta, Ankit et al.

Part of Developmental Cell, p. 97-108, 2015

• DOI for Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish

Lmx1b and FoxC Combinatorially Regulate Podocin Expression in Podocytes

He, Bing; Ebarasi, Lwaki; Zhao, Zhe; Guo, Jing et al.

Part of Journal of the American Society of Nephrology, p. 2764-2777, 2014

• DOI for Lmx1b and FoxC Combinatorially Regulate Podocin Expression in Podocytes

PDGF, Pericytes and the Pathogenesis of Idiopathic Basal Ganglia Calcification (IBGC)

Betsholtz, Christer; Keller, Annika

Part of Brain Pathology, p. 387-395, 2014

• DOI for PDGF, Pericytes and the Pathogenesis of Idiopathic Basal Ganglia Calcification (IBGC)

Double function at the blood-brain barrier

Betsholtz, Christer

Part of Nature, p. 432-433, 2014

• DOI for Double function at the blood-brain barrier

A novel podocyte gene, R3h domain containing-like inhibits non-canonical TGF-beta signalling

Ishikawa, T.; Takemoto, M.; Akimoto, Y.; Yan, K. et al.

Part of Diabetologia, 2014

Wtip- and Gadd45a-Interacting Protein Dendrin Is Not Crucial for the Development or Maintenance of the Glomerular Filtration Barrier

Xiao, Zhijie; Rodriguez, Patricia Q.; He, Liqun; Betsholtz, Christer et al.

Part of PLOS ONE, 2013

• DOI for Wtip- and Gadd45a-Interacting Protein Dendrin Is Not Crucial for the Development or Maintenance of the Glomerular Filtration Barrier
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Analysis of Mice Lacking the Heparin-Binding Splice Isoform of Platelet-Derived Growth Factor A

Andrae, Johanna; Ehrencrona, Hans; Gallini, Radiosa; Lal, Mark et al.

Part of Molecular and Cellular Biology, p. 4030-4040, 2013

• DOI for Analysis of Mice Lacking the Heparin-Binding Splice Isoform of Platelet-Derived Growth Factor A

Endocytosis regulates VEGF signalling during angiogenesis

Gängel, Konstantin; Betsholtz, Christer

Part of Nature Cell Biology, p. 233-235, 2013

• DOI for Endocytosis regulates VEGF signalling during angiogenesis

Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

Keller, Annika; Westenberger, Ana; Sobrido, Maria J.; Garcia-Murias, Maria et al.

Part of Nature Genetics, p. 1077-+, 2013

• DOI for Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

Targeting of alpha(v) integrin identifies a core molecular pathway that regulates fibrosis in several organs

Henderson, Neil C.; Arnold, Thomas D.; Katamura, Yoshio; Giacomini, Marilyn M. et al.

Part of Nature Medicine, p. 1617-1624, 2013

• DOI for Targeting of alpha(v) integrin identifies a core molecular pathway that regulates fibrosis in several organs

Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate

Furuhashi, Masao; Sjöblom, Tobias; Abramsson, Alexandra; Ellingsen, Jens et al.

Part of Cancer Research, p. 2725-2733, 2004

• DOI for Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate

Cerebrospinal fluid draining lymphatics in health and disease: advances and controversies

McDonald, Donald M.; Alitalo, Kari; Betsholtz, Christer; Engelhardt, Britta et al.

Part of Nature Cardiovascular Research, p. 1047-1065, 2025

• DOI for Cerebrospinal fluid draining lymphatics in health and disease: advances and controversies

Advances and controversies in meningeal biology

Betsholtz, Christer; Engelhardt, Britta; Koh, Gou Young; Mcdonald, Donald M. et al.

Part of Nature Neuroscience, p. 2056-2072, 2024

• DOI for Advances and controversies in meningeal biology

Toward a granular molecular-anatomic map of the blood vasculature - single-cell RNA sequencing makes the leap

Betsholtz, Christer

Part of Upsala Journal of Medical Sciences, 2022

• DOI for Toward a granular molecular-anatomic map of the blood vasculature - single-cell RNA sequencing makes the leap
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Identification, discrimination and heterogeneity of fibroblasts

Lendahl, Urban; Muhl, Lars; Betsholtz, Christer

Part of Nature Communications, 2022

• DOI for Identification, discrimination and heterogeneity of fibroblasts
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The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes

Hariharan, Ashwini; Weir, Nick; Robertson, Colin; He, Liqun et al.

Part of Frontiers in Cellular Neuroscience, 2020

• DOI for The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes
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Emerging links between cerebrovascular and neurodegenerative diseases-a special role for pericytes

Lendahl, Urban; Nilsson, Per; Betsholtz, Christer

Part of EMBO Reports, 2019

• DOI for Emerging links between cerebrovascular and neurodegenerative diseases-a special role for pericytes

Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing

van Kuijk, Kim; Kuppe, Christoph; Betsholtz, Christer; Vanlandewijck, Michael et al.

Part of Cardiovascular Research, p. 1705-1715, 2019

• DOI for Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing

Alternative lymphatic endothelial progenitor cells compensate for the loss of non-venous-derived progenitors to form mesenteric lymphatic vessels

Zhang, Yang; Stritt, Simon; Martinez-Corral, Ines; Laviña, Bàrbara et al.

Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations: Cdc42 and vascular malformations

Laviña, Bàrbara; Castro, Marco; Niaudet, Colin; Bert, Cruys et al.