Globisch Group
Biomarker discovery, chemical biology, organic chemistry, mass spectrometry, and metabolomics
Biomarker discovery is a challenging and multidisciplinary task. We develop new tools for mass spectrometric analysis of complex samples and are focussed on elucidating microbiota metabolism. We investigate any human sample type, e.g. fecal, urine, and plasma samples from pancreatic cancer patients.
Group members
Publications
Part of Angewandte Chemie International Edition, 2024
Identification of New Ketamine Metabolites and Their Detailed Distribution in the Mammalian Brain
Part of ACS Chemical Neuroscience, p. 1335-1341, 2024
The protective role of commensal gut microbes and their metabolites against bacterial pathogens
Part of Gut microbes, 2024
Part of EBioMedicine, 2024
Part of European Journal of Pharmaceutical Sciences, 2024
A frame-shift mutation in COMTD1 is associated with impaired pheomelanin pigmentation in chicken
Part of PLOS Genetics, 2023
Part of Analytical Chemistry, p. 12565-12571, 2023
Identification of nutritional biomarkers through highly sensitive and chemoselective metabolomics
Part of Food Chemistry, 2023
Part of Chemical Science, p. 5291-5301, 2023
Part of Chemical Communications, p. 5843-5846, 2023
Part of Journal of Crohn's & Colitis, p. 418-432, 2023
- DOI for Mucosal and Plasma Metabolomes in New-onset Paediatric Inflammatory Bowel Disease: Correlations with Disease Characteristics and Plasma Inflammation Protein Markers
- Download full text (pdf) of Mucosal and Plasma Metabolomes in New-onset Paediatric Inflammatory Bowel Disease: Correlations with Disease Characteristics and Plasma Inflammation Protein Markers
Part of Biochemical Pharmacology, 2022
Part of Microbiology Spectrum, 2022
- DOI for Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
- Download full text (pdf) of Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors
Regional Brain Analysis of Modified Amino Acids and Dipeptides during the Sleep/Wake Cycle
Part of Metabolites, 2022
Part of Journal of Experimental & Clinical Cancer Research, 2021
- DOI for Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis
- Download full text (pdf) of Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis
Part of Journal of Cerebral Blood Flow and Metabolism, p. 3324-3338, 2021
Chemoselective and Highly Sensitive Quantification of Gut Microbiome and Human Metabolites
Part of Angewandte Chemie International Edition, p. 23232-23240, 2021
Part of RSC CHEMICAL BIOLOGY, p. 1479-1483, 2021
Part of RSC Advances, p. 34788-34794, 2021
Part of Journal of Pharmaceutical and Biomedical Analysis, 2021
Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA-Peptide World
Part of Chemistry - A European Journal, p. 14856-14860, 2020
Part of Free Radical Biology & Medicine, p. 745-754, 2020
DNA surface exploration and operator bypassing during target search
Part of Nature, p. 858-+, 2020
Part of The Analyst, p. 3822-3831, 2020
Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N-Acetyltransferase NAT2
Part of Angewandte Chemie International Edition, p. 14342-14346, 2020
Rapid Preparation of a Large Sulfated Metabolite Library for Structure Validation in Human Samples
Part of Metabolites, 2020
Part of Chemical Communications, p. 9080-9083, 2019
Part of Bioorganic & Medicinal Chemistry, p. 955-962, 2019
Part of ChemBioChem, p. 1678-1683, 2019
Part of Organic and biomolecular chemistry, p. 698-702, 2018
Part of Chemical Science, p. 6233-6239, 2018
Part of Angewandte Chemie International Edition, p. 13805-13809, 2018
Noninvasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis
Part of ACS - Infectious Diseases, p. 1423-1431, 2018
Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG)
Part of Bioorganic & Medicinal Chemistry Letters, p. 3436-3440, 2017
Effect of Antibiotic Treatment on the Gut Metabolome of Pigs
Effect of Antibiotic Treatment on the Gut Metabolome of Pigs