POAKIDS

This project aims to conduct a European, prospective, multicenter, observational study to determine the incidence of Postoperative Acute Kidney Injury (PO-AKI) in hospitalized children after noncardiac surgery.

In the same subjects we also intend to evaluate urinary biomarkers as predictors of PO-AKI. The study employs modern standardized classifications for AKI to comprehensively address the issue of PO-AKI in children. Describing the incidence and identifying risk factors for PO-AKI will play a crucial role in developing preventive strategies aimed at reducing associated mortality and morbidity. Furthermore, investigating the relationship between urinary biomarkers of renal injury and PO-AKI will provide valuable insights into assessing postoperative renal function in paediatric patients, especially when repeated blood sampling is not feasible.

To explore the incidence of Acute Kidney Injury (AKI) after noncardiac surgery and anaesthesia, and associated urinary biomarkers and risk factors, children will be recruited in paediatric surgical centres across Europe. AKI will be determined based on changes in plasma-creatinine (before vs after surgery).