Chameleonic properties make large molecules into possible drugs
17 oktober 2016
In a paper published today in Nature Chemical Biology, a team of researchers from Uppsala University, the Broad Institute of MIT, Harvard, and AstraZeneca are presenting new insights into how larger-than-average molecules can be developed into pharmaceutical drugs.
Ancient fish illuminates one of the mysteries of childhood
17 oktober 2016
Remember dropping your milk teeth? After a lot of wiggling the tooth finally dropped out. But in your hand was only the enamel-covered crown: the entire root of the tooth had somehow disappeared. In a paper published in Nature, a team of researchers from Uppsala University and the ESRF in France apply synchrotron x-ray tomography to a tiny jawbone of a 424 million year old fossil fish in order to illuminate the origin of this strange system of...
Conclusions on ending childhood obesity from Uppsala Health Summit 2016
14 oktober 2016
Uppsala Health Summit concluded its deliberations on how to end childhood obesity this week with a number of recommendations to governments, the food industry and numerous other stakeholders.
Conclusions from Uppsala Health Summit 11 -12 October 2016
13 oktober 2016
The following are conclusions and proposals developed during the multi-party dialogues held during Uppsala Health Summit, 11 – 12 October 2016:
Erasmus+ Capacity building project launch EVENT
11 oktober 2016
In competition with a large number of other academic institutions, Uppsala University has been given the task of coordinating the project EVENT, European and Vietnamese Collaboration on Graduate Employment). EVENT is an Erasmus+ Capacity Building project that focuses on Vietnam through EU funding.
Childhood obesity on the agenda as experts gather in Uppsala
11 oktober 2016
At Uppsala Health Summit on childhood obesity, which starts today on World Obesity Day, experts from health organisations, the academic community, the business sector and non-governmental organisations meet to discuss how we can work together to combat the ongoing obesity epidemic.
Magma movements foretell future eruptions
07 oktober 2016
Geologists at Uppsala University have traced magma movement beneath Mt. Cameroon volcano, which will help monitoring for future volcanic eruptions. The results are published in Scientific Reports.
New efficient and low-cost method for hydrogenation of graphene with visible light
06 oktober 2016
An environmentally friendly, efficient and low-cost method for hydrogenation of graphene with visible light has been developed by researchers at Uppsala University and AstraZeneca Gothenburg, Sweden. The research study is presented in an article in Nature Communications.
Roundworms even more useful than researchers previously thought
05 oktober 2016
The one millimetre long roundworm Caenorhabditis elegans has been used as a model organism in scientific research, and has therefore been extensively examined. A research group at Uppsala University has now demonstrated that the worm is an even more complete model system than previously thought, which could enable more detailed research into areas such as early embryonic development.
"The Nobel Prize in Economics” and society
05 oktober 2016
In 1968, the scientific status of economics was strengthened by the creation of the “Nobel Prize in Economic Sciences”. After financial crises, low economic growth and increasing social tension, many are questioning this scientific status. In a new book, Uppsala researcher Gabriel Söderberg and Avner Offer at Oxford University draw the conclusion that the Economics Prize indirectly has also contributed to undermining the scientific status of e...
The psychology behind climate change denial
04 oktober 2016
Climate change is a serious threat to humans, animals, and the earth’s ecosystems. Nevertheless, effective climate action has been delayed, partly because some still deny that there is a problem. In a new thesis in psychology, Kirsti Jylhä at Uppsala University has studied the psychology behind climate change denial. The results show that individuals who accept hierarchical power structures tend to a larger extent deny the problem.
Eat, escape, love: the price of looking sexy
27 september 2016
In the animal kingdom colourful traits can be both a blessing and a curse. A new study from a group of researchers at Uppsala University has studied the conspicuous wing coloration of two species of damselflies. Their results imply that males, but not females, pay a high cost when using colour to communicate with other damselflies, both in terms of predation risk and visibility to prey.
Short sleep increases blood lipids tied to hunger and mood in humans before but not after a work out
26 september 2016
Chronic lack of sleep has been linked to an increased risk of overweight and obesity and previous studies have demonstrated that healthy participants who are sleep deprived eat more, make unfavorable food choices and crave more high-calorie foods. Now, a group at Uppsala University has investigated how levels of endocannabinoids – which target the same receptors as cannabis – are affected by short sleep duration, and whether acute exercise can...
Artificial intelligence reveals mechanism behind brain tumour
19 september 2016
Researchers at Uppsala University have used computer modelling to study how brain tumours arise. The study, which is published today in the journal EBioMedicine, illustrated how researchers in the future will be able to use large-scale data to find new disease mechanisms and identify new treatment targets.
The memory of a heart attack is stored in our genes
16 september 2016
Both heredity and environmental factors influence our risk of cardiovascular disease. A new study, by researches at Uppsala University, shows now that the memory of a heart attack can be stored in our genes through epigenetic changes. The results have been published in the journal Human Molecular Genetics.
Donation for New Sociology Prize
09 september 2016
Uppsala University has received its first donation for sociology to be used for the Hans L. Zetterberg Prize “to be awarded yearly to a younger researcher, Swedish or foreign, who, with his/her scientific work in sociology, preferably through fruitful combination of theory and practice, has moved the research front forward.” The prize will be awarded annually and is to be considered international. The monetary value of the prize is SEK 100 000...
Uppsala Health Summit 11-12 October: Pre-conference report
08 september 2016
A report has been released for the upcoming Uppsala Health Summit on ending childhood obesity, outlining the challenges, including the effectiveness of the much debated sugar-tax, how to target interventions for immigrants and the role of industry. The report is produced to prepare the 200 delegates for discussions on concrete solutions.
Life history of the 360 million-year-old Acanthostega rewrites the tetrapod move on land
07 september 2016
This week in the journal Nature, an international team of researchers shows that fossils of the 360 million-year-old tetrapod Acanthostega, one of the iconic transitional forms between fishes and land animals, are not grown-ups but all juveniles. This conclusion, which is based on high-resolution synchrotron X-ray scans of fossil limb bones, sheds new light on the life cycle of Acanthostega and the so-called conquest of land by tetrapods.
Sustainable peace is more than lack of violence
06 september 2016
In a world of conflict and violence new knowledge on how to build sustainable peace is urgently needed. In his dissertation PhD candidate Florian Krampe emphasizes the need for helping countries to reset their internal relations on a peaceful path.
Flycatcher genome sheds light on causes of mutations
06 september 2016
A research team at Uppsala University has determined the complete genetic code of 11 members of a flycatcher pedigree. Doing this, they have for the first time been able to estimate the rate of new mutations in birds. When they combined the new results with mutation rate estimates from other organisms, a clear pattern emerged: The more common a species is, the lower its mutation rate.
Biobank storage time as important as age
05 september 2016
The amount of time a blood sample used for medical research has been stored at a biobank may affect the test results as much as the blood sample provider’s age. These are the findings of a new study from Uppsala University, which was published in the scientific journal EBioMedicine. Until now, medical research has taken into account age, sex and health factors of the person providing the sample, but it turns out that storage time is just as im...
Controlling the amount of heparan sulphate – a carbohydrate needed for foetal development
02 september 2016
Heparan sulphate occurs as carbohydrate chains which are very important for human body cells both for normal foetal development and during the course of various diseases. All new molecular knowledge concerning these chains is therefore important. Researchers can now show that the same enzyme which determines the charge pattern of the chains also determines their length.
Forensic DNA analysis checks the origin of cultured cells
31 augusti 2016
Cell lines are cultured cells that are commonly used in medical research. New results from Uppsala University show that such cells are not always what they are assumed to be. Using genetic analyses, the researchers showed that a commonly used cell line which was established in Uppsala almost fifty years ago does not originate from the patient it is claimed to stem from. The findings are published today in the journal Science Translational Medi...
Magnetism under the magnifying glass
31 augusti 2016
Being able to determine magnetic properties of materials with sub-nanometer precision would greatly simplify development of magnetic nano-structures for future spintronic devices.
Memory activation before exposure reduces life-long fear of spiders
25 augusti 2016
Many people suffer from anxiety and fears, and a common treatment for these problems is exposure therapy. In a new study published in Current Biology, researchers at Uppsala University have shown how the effect of exposure therapy can be improved by disrupting the recreation of fear-memories in people with arachnophobia.
New study provides important insight into how tumours metastasise
23 augusti 2016
Research has shown that the growth of cancerous tumours is affected by the transforming growth factor beta (TGF-beta) in the body’s cells; TGF-beta both suppresses and stimulates tumour development, but it has not been understood how this happens. A new study published in the journal Science Signaling today reveals important details behind this process.
Kevin Anderson is the new Zennström visiting Professor in Climate Change Leadership
22 augusti 2016
Climate researcher Kevin Anderson will be Uppsala University’s second holder of the Zennström visiting professorship in Climate Change Leadership. He will continue the work of Doreen Stabinsky in establishing an academic environment that will be unique, both in Sweden and in the world.
Polyunsaturated fat in adipose tissue linked to lower mortality
17 augusti 2016
In a study from Uppsala University, published in the American journal JAMA Cardiology, the fatty acid linoleic acid (Omega 6) in subcutaneous adipose tissue was linked to lower mortality among older men followed over a 15-year period.
Plenty of light during daytime reduces the effect of blue light screens on night sleep
10 augusti 2016
The use of smartphones and tablet computers during evening hours has previously been associated with sleep disturbances in humans. A new study from Uppsala University now shows that daytime light exposure may be a promising means to combat sleep disturbances associated with evening use of electronic devices. The findings are published in the scientific journal Sleep Medicine.
Simplified approach to drug development with Upsalite
09 augusti 2016
For the first time, researchers have revealed the nanostructure of the mesoporous magnesium carbonate Upsalite® and pore size control was achieved without organic templates or swelling agents. By controlling the pore structure of the material the amorphous phase stabilisation exerted on poorly soluble drug compounds can be tuned and the drug delivery rate can be tailored.
Limestone assimilation under volcanoes helps understand Earth’s carbon cycle
08 augusti 2016
In a new study researchers from Sweden and Italy show what happens when magma meets limestone on its way up to the surface. Magma-limestone interaction might help explain why volcanoes like Vesuvius in Italy and Merapi in Indonesia are particularly explosive and, moreover, it helps us to understand another source of natural carbon released to the atmosphere by volcanoes.
Antidepressants boost cognitive behavioural therapy for social anxiety
30 juni 2016
Treatments for social anxiety disorder often include either selective serotonin reuptake inhibitors (SSRIs) or cognitive behavioural therapy (CBT), but new research from Uppsala University indicates that social anxiety disorder is best treated with the combination of SSRI and CBT, which also improves emotion processing in the brain.
Evolution of vertebrate vision
15 juni 2016
A new study published in BMC Evolutionary Biology by the team lead by Xesús Abalo and Dan Larhammar, Department of Neuroscience at Uppsala University and SciLifeLab, sheds light on the evolutionary origin fast vertebrate vision and the specialisations in zebrafish to adapt to changing lighting conditions
Upward trend in fatalities in organized violence was broken in 2015
14 juni 2016
The alarming upward trend in fatalities in organized violence, witnessed over the last few years, was broken in 2015. This is evident from new data from the Uppsala Conflict Data Program (UCDP), Uppsala University. The number of armed conflicts involving states continued to increase, however, going from 41 in 2014 to as many as 50 in 2015.
How honeybees do without males
09 juni 2016
An isolated population of honeybees in South Africa, the Cape bees, has evolved a strategy to reproduce without males. A team of researchers at Uppsala University and in South Africa has sequenced the entire genomes of a sample of Cape bees and compared them with other populations of honeybees to find out the genetic mechanisms behind their asexual reproduction.
Microplastic particles threaten fish larvae
02 juni 2016
Please note! The scientific article that this press release refers to have been retracted from the journal Science.
Loss of Y chromosome in blood cells associated with developing Alzheimer’s disease
24 maj 2016
Men with blood cells that do not carry the Y chromosome are at greater risk of being diagnosed with Alzheimer’s disease. This is in addition to an increased risk of death from other causes, including many cancers. These new findings by researchers at Uppsala University could lead to a simple test to identify those at risk of developing Alzheimer’s disease.
New method to create terahertz radiation advances materials science
23 maj 2016
Uppsala physicists have in an international collaboration developed a new method for creating laser pulses which are shorter, have much higher intensity and cover the THz frequency range better than current sources. The study is published today in the authoritative journal Nature Photonics and is of great importance to materials research.
Mille-feuille-filter removes viruses from water
18 maj 2016
A simple paper sheet made by scientists at Uppsala University can improve the quality of life for millions of people by removing resistant viruses from water. The sheet, made of cellulose nanofibers, is called the mille-feuille filter as it has a unique layered internal architecture resembling that of the French puff pastry mille-feuille (Eng. thousand leaves).
New study shows how shift work affects cognitive functions
17 maj 2016
A new study from Uppsala University shows that compared to non-shift workers, shift workers needed more time to complete a test that is frequently used by physicians to screen for cognitive impairment. However, those who had quit shift work more than five years ago completed the test just as quick as the non-shift workers. The findings are published in the journal Neurobiology of Aging.
Second gene modifies effect of mutation in DM, a dog model of ALS
16 maj 2016
Canine Degenerative Myelopathy (DM) is a neurodegenerative disease in dogs with similarities to ALS in humans. Scientists at Uppsala University, SciLifeLab, the Broad Institute of MIT and Harvard, and the University of Missouri, have discovered a modifier gene that affects the risk of developing DM in Pembroke Welsh Corgis. The study is published in PNAS this week.
Childhood obesity in focus at 2016 Uppsala Health Summit
16 maj 2016
In just a few decades, the number of overweight and obese adults and children in the world has reached alarming levels, not least in low-income countries. This year, Uppsala Health Summit is taking place in conjunction with World Obesity Day: 11-12 October 2016. International experts on child obesity will gather to discuss countermeasures with industry, policy makers and society.
Why animals court their own sex
13 maj 2016
Same-sex sexual behavior is common in animals but puzzles evolutionary biologists since it doesn’t carry the same obvious benefits as heterosexual courtship behavior that leads to mating and production of offspring. A study from Uppsala University sheds new light on the pervasiveness of same-sex sexual behavior in the animal kingdom.
Dogs provide information about brain tumour development in humans
12 maj 2016
Brain tumours in dogs are strikingly similar to their human tumour counterparts. In a recent study in the journal PLOS Genetics, researchers at Uppsala University and Swedish University of Agricultural Sciences have used genetic analyses in different dog breeds to identify genes that could have a role in the development of brain tumours in both dogs and human.
Coral death stops fish from learning predators
11 maj 2016
In a world first study researchers have found that coral bleaching and death can have dramatic repercussions for how small reef fish learn about and avoid predators. The new results are published in the journal Proceedings of the Royal Society B.
Genetic test shows patients at risk of a serious adverse reaction to toxic goitre treatment
04 maj 2016
Researchers and doctors at Uppsala University, along with Swedish and international collaboration partners, have found gene variants that predict the risk of a serious adverse reaction to drugs used for the treatment of hyperthyroidism. The results are published in The Lancet Diabetes & Endocrinology.
Evolution in action detected in Darwin’s finches
21 april 2016
The most characteristic feature of Darwin’s finches is the diversification of beak morphology that has allowed these species to expand their utilization of food resources in the Galápagos archipelago. A team of scientists from Uppsala University and Princeton University has now identified a gene that explains variation in beak size within and among species. The gene contributed to a rapid shift in beak size of the medium ground finch following...
Bird genomes contain ‘fossils’ of parasites that now infect humans
21 april 2016
In rare instances, DNA is known to have jumped from one species to another. If a parasite’s DNA jumps to its host’s genome, it could leave evidence of that parasitic interaction that could be found millions of years later — a DNA ‘fossil’ of sorts. An international research team led from Uppsala University has discovered a new type of so-called transposable element that occurred in the genomes of certain birds and nematodes.
Lowered birth rates one reason why women outlive men
18 april 2016
Using unique demographic records on 140,600 reproducing individuals from the Utah Population Database (USA), a research team led from Uppsala University has come to the conclusion that lowered birth rates are one reason why women outlive men in today’s societies. The study is published in Scientific Reports.
Jon Elster awarded this year’s Johan Skytte Prize in Political Science
08 april 2016
The Johan Skytte Prize annually recognizes the most valuable contribution to the field of Political Science. This year’s prize is awarded to Professor Jon Elster, Robert K. Merton Professor in Social Sciences at Columbia University and titular professor at College de France, Paris.