Research at Uppsala University
History of human antibiotic use written in the oral bacteria of wild brown bears
25 August 2021. An international team of researchers used historical museum collections to study the effects of huma ...
How research can encourage us to cycle instead
19 August 2021. How do you get to work in the mornings? Transport currently accounts for 25 per cent of GHG emission ...
Philippine ethnic group has most Denisovan DNA
13 August 2021. The Philippine ethnic group Ayta Magbukon has the highest proportion of genes from our extinct relat ...
Search for research projects
Here you will find all research projects at Uppsala University funded by the main Swedish funding bodies. The search feature is based on the SweCRIS database.
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Your choice produced 24 hits
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A digital antimicrobial stewardship smartphone application to combat AMR: the AB-assistant
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Research project from 2017-12-01 to 2019-12-31
Antimicrobials are an indispensable part of modern medicine. Improvement of antimicrobial use, in particular prevention of overuse of (broadspectrum) antibiotics, through antimicrobial stewardship (AMS ...
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Aiming at prolonging the therapeutic lifespan of artemisinin-based combination therapies in an era of imminent Plasmodium falciparum resistance in East-Africa - new strategies with old tools
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Research project from 2017-01-01 to 2019-12-31
Global malaria control is under threat due to evolution and spread of P. falciparum resistance to artemisinin-based combination therapies (ACTs) in Southeast Asia. Artemisinin resistance is phenotypically ...
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Antibiotic induced persistence in Mycobacterium tuberculosis
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Research project from 2014-01-01 to 2016-12-31
Drug-resistant Mycobacterium tuberculosis, the causative agent of tuberculosis, poses a significant threat to global health. It is proposed that persister cells are important for development of drug resistance ...
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Antimicrobial resistance in the environment and human health impact
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Research project from 2017-01-01 to 2020-12-31
Antimicrobial resistance is a rapidly growing health concern but environmental aspects are largely understudied. Here, a 2017-2020 multi-disciplinary project is proposed in which development and transfer ...
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Campylobacter infections - connecting bacterial pathogenicity mechanisms to human disease outcome
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Research project from 2012-01-01 to 2014-12-31
Campylobacter is the most common cause of bacterial gastroenteritis in the western world, estimated to cause several million infections annually in the EU. Campylobacter infections burden the Swedish society ...
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Metropolitan mosquitoes: Understanding urban livestock keeping and vector-borne disease in growing tropical cities - the potential of sustainable control methods and the risks for emergence to Sweden.
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Research project from 2016-01-01 to 2020-12-31
With more than 50% of the global population living in urban areas, cities are not only crowded with humans, but also with the livestock brought there to provide for high value animal-source food products ...
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Clinical validation of new diagnostic method for tick-transmitted infections
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Research project from 2014-11-03 to 2017-07-30
Purpose and goal: A technically verified and primarily validated whole new ELISA prototype for screening diagnostics of rickettsia infections has been developed based on tests of retro- and prospectively ...
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Covid-19 and androgen deprivation therapy for prostate cancer. Populationbased studies
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Research project from 2020-08-01 to 2020-12-31
The aim of this study is to assess the association between androgen deprivation therapy (ADT) and risk of Covid-19 under the hypothesis that ADT inhibits/ mitigates Covid-19 through inhibition of TMPRSS2 ...
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Developing combinations of CO-ACTIVE antimicrobials and non-antimicrobials
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Research project from 2015-12-01 to 2018-11-30
The CO-ACTION project aims to develop and provide a framework for evaluating and validating the effectiveness of antibiotic (AB)- and non-antibiotic (NA) combinations (COMs) in the preclinical setting ...
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Development of a Egyptian-Swedish One Health collaboration on antibiotic resistance in poultry and the impact on human health
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Research project from 2020-01-01 to 2021-12-31
Global food demand is increasing, especially with regard to animal products, therefore global livestock production has to rely on extensively on antimicrobial use (AMU) to comply with rising consumer demands ...
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Eosinophil secretory proteins in health and disease
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Research project from 2013-01-01 to 2015-12-31
The overall aim of this project is the understanding of the role of the human eosinophil granulocyte in health and disease. Our strategy is to approach the question from three angels. 1: The identification ...
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Evolution of Influenza A Virus and Antiviral Resistance
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Research project from 2014-01-01 to 2016-12-31
Få mikroorganismer har så stor inverkan på människors och djurs hälsa som influensa A virus (IAV). IAV finns hos änder men korsar artbarriärer och infekterar tamfåglar, däggdjur och människa. Fågelvirus ...
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redicting, preventing and diagnosing antibiotic resistance
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Research project from 2009-07-01 to 2014-06-30
Currently not available ...
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Sustainable use of antivirals in seasonal influenza and pandemic preparedness – ranking risk of environmental resistance development and understanding resistance transmission towards humans
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Research project from 2017-01-01 to 2019-12-31
Influenza is a major public health threat and anti-influenza drugs are crucial for treatment and prophylaxis, especially early in a pandemic, before vaccines can be mass-produced. However, antiviral drugs ...
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INFECTION BIOLOGY IN FISH: UNDERSTANDING SPIRONUCLEUS INFECTIONS OF SALMONIDS
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Research project from 2013-11-12 to 2016-12-31
The fastest growing food sector in the world is aquaculture, with salmon and carp being the two most important fish species used in fish farming. Infections are well-known problems in fish farming, involving ...
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Sensiting Pseudomonas aeruginosa biofilms to antibiotics and reducing virulence through novel target inhibition
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Research project from 2014-01-01 to 2016-12-31
JPIAMR ansökan: Sensiting Pseudomonas aeruginosa biofilms to antibiotics and reducing virulence through novel target inhibition ...
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Neuraminidase inhibitors in the environment and resistance development in influenza A virus: implications for public health
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Research project from 2014-01-01 to 2016-12-31
The active metabolite of the neuraminidase inhibitor (NAI) oseltamivir (OS), oseltamivir carboxylate (OC) degrades poorly in sewage treatment and can enter aquatic environments. Dabbling ducks constitute ...
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Understanding and preventing plasmid borne antibiotic resistance.
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Research project from 2013-01-01 to 2016-12-31
The projects in this application are aimed at increasing our understanding of what factors balance the costs and benefits of plasmids for pathogenic bacteria and how plasmids and their hosts co-evolve ...
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Optimised use of antibiotics to improve clinical efficacy and reduce the risk of resistance development
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Research project from 2021-01-01 to 2023-12-31
The emergence and spread of multidrug-resistant bacteria results in treatment failure and increased mortality in common infections. Moreover, antibiotic resistance threatens all parts of modern medicine ...
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Optimised use of antibiotics to improve clinical efficacy and reduce the risks of side effects and resistance development
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Research project from 2019-12-01 to 2021-12-31
The emergence and spread of multidrug-resistant bacteria, driven by the massive overuse of antibiotics, results in treatment failure for common infections, increased mortality in the critically ill and ...
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Piloting on-site interventions for reducing antimicrobial use in livestock farming in emerging economies
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Research project from 2017-12-01 to 2019-12-31
Increasing intensification and expansion of the livestock sector in emerging economies is a large user of antimicrobials, driving the global emergence of antimicrobial resistant bacteria in livestock, ...
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Putting a STOP to infectious diseases: exploring the potential of the type II NADH-menaquinone oxidoreductase (Ndh2) as a target for new drugs
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Research project from 2012-01-01 to 2012-12-31
The work described is a multidisciplinary effort in drug design. We will focus on an enzyme for which we have special knowledge and experience, and compounds active against mycobacteria, and explore its ...
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Rickettsia helvetica, virulence factors and cellular aspects of Pathogenicity
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Research project from 2016-01-04 to 2017-01-02
Purpose and goal: The mobility grant allowed the candidate to spend 25% of her time for one year at Alpha Biotech, giving not just her personally but also the department at Uppsala University a natural ...
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Selection of resistant bacteria at very low antibiotic concentrations in the environment
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Research project from 2014-01-01 to 2016-12-31
Antibiotics represent the most important drug class ever used in medicine but the use/abuse of antibiotics has resulted in selection for resistant bacteria that threaten to return us to a post-antibiotic ...
Showing 24 Of 24 hits
Research spotlight: The coronavirus
New method for discovery of antiviral drugs
2 August 2021. The current COVID-19 pandemic has highlighted the need for methods to identify new or repurposed dru ...
Helpline important for older people during the pandemic
8 July 2021. For many older individuals, the COVID-19 pandemic has resulted in the loss of daily anonymous contac ...
The national COVID-19 Data Portal turns one year old
3 June 2021. The national Swedish COVID-19 Data Portal was launched one year ago to support researchers in utilis ...
Lectures
Uppsala University’s researchers share their knowledge in public lectures. Every year, the University is visited by leading researchers and influential people from around the world. At Uppsala University, you can hear Nobel laureates, researchers, authors, politicians and many others give lectures. Here we present some of the most prominent, annually occurring lectures at Uppsala University.