Research at Uppsala University
History of human antibiotic use written in the oral bacteria of wild brown bears
25 August 2021. An international team of researchers used historical museum collections to study the effects of huma ...
How research can encourage us to cycle instead
19 August 2021. How do you get to work in the mornings? Transport currently accounts for 25 per cent of GHG emission ...
Philippine ethnic group has most Denisovan DNA
13 August 2021. The Philippine ethnic group Ayta Magbukon has the highest proportion of genes from our extinct relat ...
Search for research projects
Here you will find all research projects at Uppsala University funded by the main Swedish funding bodies. The search feature is based on the SweCRIS database.
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Your choice produced 43 hits
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3rd Frontiers in Medicinal Chemistry Meeting: Emerging Targets, Novel Candidates and Innovative Strategies
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Research project from 2011-01-01 to 2011-12-31
Undertecknad är "co-chair" av det internationella läkemedelskemimötet ?Frontiers in Medicinal Chemistry?. Detta arrangeras nu för tredje gången och Stockholm har blivit utsedd som värd (19-21/6, 2011). ...
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7th European Conference on Marine Natural Products (7ECMNP)http://www.fkog.uu.se/7ECMNP
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Research project from 2011-01-01 to 2011-12-31
Denna konferens är den 7:e i en serie av möten inom marin naturproduktforskning som anordnas vartannat år av Europeiska forskare. Professor Lars Bohlin med medarbetare har fått hedersuppdraget att för ...
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A Light-Induced Route to New Sustainable Biocrudes for Lubricant Oils
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Research project from 2018-01-01 to 2020-12-31
The project aims at the development of a novel photochemical process for production of sustainable fossil-free lubricant oils from compounds obtained from Swedish biosources. For a variety of different ...
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Active Site Models of Hydrogenase Enzymes and Unexplored Phosphaorganic Chemistry
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Research project from 2016-01-01 to 2019-12-31
In project A, we will synthesize bioinorganic model complexes of the [FeFe] and the [Fe] hydrogenase (H2ase) active sites. The role of the second coordination sphere and the protein matrix in [FeFe] H2ases ...
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Alkenes from Reductive Carbonyl-Carbonyl Coupling Reactions
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Research project from 2020-01-01 to 2023-12-31
The project fuses low-coordinate phosphorus chemistry and carbonyl olefinations with the aim to develop unprecedented alkene formation reactions from the reductive cross-coupling of two carbonyl compounds ...
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Pushing the boundaries of the nucleophilic aromatic substitution through photochemistry
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Research project from 2017-02-01 to 2018-06-30
Purpose and goal: The project had two goals; (i) to establish longterm research contacts between my research group at UU and AstraZeneca and (ii) to develop the photo-SNAr reaction. Both goals have been ...
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BIOBATT - Biomass-derived materials for sustainable high-capacity batteries with energy and resource efficient recycling
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Research project from 2017-01-01 to 2019-12-31
This project aims for the development of Li-ion batteries produced primarily from biomass resources, and where lithium can be recycled using low-temperature processing and non-toxic conditions. Such a ...
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Bioinorganic Enzyme Active Site Models of Energy Relevance and the Coordination Chemistry of Acetylenic Phosphaalkenes
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Research project from 2010-10-01 to 2016-09-30
In project A, we will synthesize bioinorganic model complexes of the [FeFe] and the [Fe] hydrogenase (H2ase) active sites. The design of the [FeFe]-H2ase mimics is guided by functional aspects which will ...
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Fuels from Sun: 3D Organic Semiconducting Polymer Nano-Dots as Efficient Photocatalysts for Hydrogen Evolution and CO2 Reduction
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Research project from 2018-01-01 to 2021-12-31
My recent ground-breaking finding (Angew Chem Int Ed., 2016, 55, 12306, Hot Paper) shows that three dimensional organic polymer nano-dots (Pdots) prepared from pristine polymers are a family of efficient ...
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Catalytic Stereospecific Substitutions of Alcohols: A Green Solution to a Problematic Transformation in Chemistry
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Research project from 2012-01-01 to 2014-12-31
When substitution of the hydroxyl group of an alcohol is performed in traditional synthesis, the alcohol is first converted into a more reactive ester or halide in an extra synthetic step. Besides lowering ...
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Design and synthesis of luminescent compounds to study biological processes
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Research project from 2014-01-01 to 2017-12-31
The aim of the proposed work is the development of new fluorescent tools to investigate biological phenomena. First, new, spectroscopically active base analogues, and nucleic acid-compatible lanthanide ...
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Design of chemical tools for drug discovery beyond the ¨rule of 5¨
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Research project from 2017-01-01 to 2020-12-31
Many novel targets, in particular protein-protein interactions (PPIs), cannot be modulated with small drug-like molecules. Instead, compounds in a different chemical space, e.g. macrocycles and peptides ...
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Designed polypeptides - structure and function
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Research project from 2011-01-01 to 2013-12-31
A unique concept for the molecular recognition of proteins has been developed that dramatically shortens the time for development of powerful binder molecules. It is based on the conjugation of small organic ...
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Developing a Universal Chiral Halofunctionalization Agent: A New Sustainable Chemical Methodology
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Research project from 2018-01-01 to 2020-12-31
Electrophilic halofunctionalization of alkenes is a fundamental chemical transformation. Nonracemic chiral halogenated molecules, the products of asymmetric halofunctionalization, are amongst the most ...
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Development of a Universal Enantioselective Halofunctionalization Strategy
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Research project from 2021-01-01 to 2024-12-31
Electrophilic halofunctionalization of alkenes is a fundamental transformation of organic chemistry. Asymmetric halofunctionalizations would deliver nonracemic chiral halogenated molecules, which are highly ...
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Programmable Oligonucleotide Delivery System for next-generation siRNA Prostate cancer thErapy
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Research project from 2020-10-01 to 2022-07-31
Purpose and goal: This project aims to develop effective, GMP-grade siRNA drugs for anticancer therapy via targeted, systemic delivery with Programmable Oligonucleotide Delivery System (PODS), resulting ...
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Paramagnetic Probe for Solution State Interaction
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Research project from 2019-08-01 to 2021-07-31
Purpose and goal: The main goal of this project is the development of an exceptional sensitive method for the recognition and 3D characterisation of weak bonding in solution. Therefore the first objective ...
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Excited State (Anti)Aromaticity and Heavy Group 14 Element Chemistry: Fundamental Studies with Potentials for Applications
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Research project from 2016-01-01 to 2019-12-31
This research proposal is centered on two areas; the first devoted to investigations of excited state aromaticity and antiaromaticity effects (shortly, excited state (anti)aromaticity) or ES(A)A) and the ...
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Exploration of East African Herbal Resources to Control Major Health Challenges
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Research project from 2017-01-01 to 2019-12-31
This study will make use of East African indigenous knowledge for the application of natural resources to control the major health and societal challenges malaria, tuberculosis and bacterial infections.Following ...
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Exploration of East African Medicinal Herbs in the Search for Novel Antibacterial Agents
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Research project from 2020-01-01 to 2022-12-31
Antimicrobial resistance has become a major threat to human health and development. As our currently used antibiotics lose efficiency, we risk rapidly increasing number of untreatable infections leading ...
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Remote Control of Selectivity in Organic Synthesis
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Research project from 2020-01-01 to 2023-12-31
Organic synthesis underpins the modern world, but it also is in constant need of more powerful and sustainable methods to create the medicines, agrochemicals and materials that make this possible.Arynes ...
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Photochemistry of iron carbene complexes
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Research project from 2021-01-01 to 2024-12-31
This project will investigate the excited state reactivity of a recently discovered class of iron complexes featuring unique nanosecond lifetimes and sizable luminescence quantum yields of their charge-transfer ...
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From Oddity to Utility: New and Enabling Synthetic Tools for Molecular Imaging and Chemical Biology
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Research project from 2019-01-01 to 2022-12-31
The invention of new methodology for the synthesis of biologically active compounds is one the most fundamental and important goals in modern organic chemistry. As the demands for new medicines, diagnostic ...
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Greener, Cleaner and Faster Routes to Heterocycles
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Research project from 2012-01-01 to 2015-12-31
Heterocycles rank amongst the most important chemical motifs in organic, pharmaceutical and materials chemistry. However, even modern approaches to make 7-9 membered heterocycles are typically wasteful ...
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Heavy Group 14 Chemistry and Excited State Aromaticity for Molecular Electronics and Organic Synthesis
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Research project from 2012-01-01 to 2015-12-31
Three projects are proposed; two fall within molecular/organic electronics, two concern conjugation and aromaticity, and two are based on heavy Group 14 element compounds. Molecular electronic structure ...
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Hybrid molecular and semiconductor systems for solar fuel production. Fundamental science of molecular components and devices.
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Research project from 2015-01-01 to 2018-12-31
Direct solar energy conversion into a storable solar fuel is an attractive renewable energy concept. In Sweden this would allow storage of solar energy from summer to winter. Our scientific and technological ...
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Targeting hypoxia in cancer diagnosis and therapy
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Research project from 2019-01-01 to 2022-12-31
Oxygen deficiency (hypoxia) is a feature of most cancer tumors that is associated with poor prognosis, chemoresistance and metastatic progression. Thus, the development of imaging agents that target cancer-specific ...
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Oskar Widman Symposium in Organic Synthesis
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Research project from 2011-01-01 to 2011-12-31
Oskar Widman var den första Professorn i Sverige som ägnade hela sin karriär åt den organiska kemin. Han var den högst renommerade forskaren i Sverige inom detta fält under sin livstid. Vårt främsta mål ...
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Inhibition studies of metallo-beta-lactamases as target proteins of antibiotic resistance
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Research project from 2014-01-01 to 2018-12-31
The appearance of superbugs producing metallo-beta-lactamases have resulted in a clinical crisis. This project intends to express and purify subclasses of metallo-beta-lactamases including NDM-1. Specific ...
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Intracellular exposure: a new parameter for prediction of toxicological outcome after exposure to endocrine disrupting chemicals?
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Research project from 2018-01-01 to 2020-12-31
Current risk assessment needs place increasing reliance on in vitro and in silico approaches to generate quantitative information based on mechanistic understanding. Despite this, compound-specific variations ...
Showing 30 Of 43 hits
Show more hitsResearch spotlight: The coronavirus
New method for discovery of antiviral drugs
2 August 2021. The current COVID-19 pandemic has highlighted the need for methods to identify new or repurposed dru ...
Helpline important for older people during the pandemic
8 July 2021. For many older individuals, the COVID-19 pandemic has resulted in the loss of daily anonymous contac ...
The national COVID-19 Data Portal turns one year old
3 June 2021. The national Swedish COVID-19 Data Portal was launched one year ago to support researchers in utilis ...
Lectures
Uppsala University’s researchers share their knowledge in public lectures. Every year, the University is visited by leading researchers and influential people from around the world. At Uppsala University, you can hear Nobel laureates, researchers, authors, politicians and many others give lectures. Here we present some of the most prominent, annually occurring lectures at Uppsala University.