Research at Uppsala University

• Advanced methods for reliable and cost efficient image processing in bio-medical applications

  Research project from 2014-02-15 to 2014-03-01

  Purpose and goal: In medical image processing, methods that maximally utilize information present in images and transcend limitations of poor image quality, are of great importance. Dr. Sladoje has had ...

• Advanced methods for reliable and cost efficient image processing in life sciences

  Research project from 2014-08-01 to 2018-04-30

  Purpose and goal: The project has considerably strengthened my academic career. It provided a number of opportunities to further develop my theoretical research in image analysis and to apply it in demand-driven ...

• Brain imaging of anhedonia networks (BRIAN) – treatment effects of magnetic stimulation in schizophrenia or depression

  Research project from 2017-01-01 to 2019-12-31

  The purpose of this project is to add state-of the-art brain imaging to a double-blind randomized controlled trial of repetitive transcranial magnetic stimulation (rTMS) for the treatment of anhedonia. ...

• Computer-aided Glioblastoma and Intracranial Aneurysms Treatment Response Quantification in Neuroradiology

  Research project from 2021-01-01 to 2023-12-31

  Purpose and goal: Improved diagnosis and treatment can reduce mortality in glioblastoma and intracranial aneurysms. Manual quantification of treatment follow-up of glioblastoma and intracranial aneurysms ...

• Design and development of radiolabeled conjugates for molecular imaging

  Research project from 2009-05-01 to 2015-04-30

  The goal of the proposed program is to develop a new generation of radiolabelled tracers for molecular radionuclide imaging. A novel class of targeting scaffold proteins, Affibody molecules, will be used ...

• Design and development of radiolabeled conjugates for molecular imaging

  Research project from 2009-05-01 to 2015-04-30

  Design och utveckling av radionuklidmärkta substanser för molekylär imaging ...

• Elucidating the etiology of type I diabetes and development of cellular therapeutic interventions to halt or reverse the disease.

  Research project from 2015-01-01 to 2018-12-31

  Type 1 diabetes (T1D) is in Sweden one of the most common chronic disorder in children, reaching more than 800 new patients per year (incidence doubled since 1990). Presently, diabetes can neither be prevented ...

• Imiomics in PET/MR studies of the obesity-diabetes-atherosclerosis disease process

  Research project from 2017-01-01 to 2019-12-31

  More studies about the associations between white and brown adipose tissue (amount, localization and metabolic activity) and present and future atherosclerosis (location, amount and degree of inflammation ...

• Whole-body integrated PET/MRI equipment for biological imaging of oncological, cardiovascular and neurological diseases

  Research project from 2012-03-01 to 2016-10-31

  The overarching goal of this proposal is to increase the understanding of human physiology and pathology by combining the information from PET and MRI and deploy this knowledge to guide diagnosis and interventions ...

• Machine learning for diagnostic decision support in radiology

  Research project from 2016-09-01 to 2017-02-28

  Purpose and goal: Large quantities of information are created every day within the healthcare sector and it constitutes a potential goldmine of clinical knowledge. However, this goldmine is today neglected ...

• Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) for studies of the obesity-diabetes-atherosclerosis disease process and its consequences

  Research project from 2013-01-01 to 2015-12-31

  The main purpose of the project is to develop and validate MRI and PET methods for studies of the obesity-diabetes-atherosclerosis disease process and its consequences with a currently funded PET-MR equipment ...

• Microscopic dynamic tidal changes in lung acini as a reason for ventilator induced lung injury in acute respiratory failure, studied in vivo by synchrotron radiation computed tomography

  Research project from 2015-01-01 to 2018-12-31

  40,000 critically ill patients are treated with ventilator per year in Sweden, and 3000 of them have severe acute respiratory failure with a mortality of about 40%. The mortality is partly due to the underlying ...

• New tools in diagnostics of adrenocortical tumours

  Research project from 2012-01-01 to 2014-12-31

  Essential hypertension is present in 20% of the Swedish population, and 10% of these presumably suffer from primary aldosteronism (PA). However, this ratio in Sweden is not fully known, why we are planning ...

• Novel cancer-targeting strategies for improved molecular radiotherapy

  Research project from 2021-01-01 to 2024-12-31

  This project focuses on improving therapeutic effects of radiotherapy by:➢ Creating novel radioactive cancer-targeting molecules for molecular radiotherapy➢ Utilizing state-of-the-art precision cancer ...

• Relationship between psychiatric condition, feeding behaviour, neuropathology and the structure of the adolescent brain

  Research project from 2012-01-01 to 2014-12-31

  We aim to use state of the art functional magnetic resonance imaging (fMRI) and voxel-based morphometry (VBM) to study how adolescent-onset eating disorders and cognitions are linked to brain structure ...

• Saving the maternal brain

  Research project from 2021-01-01 to 2023-12-31

  Purpose and aims: Preeclampsia occurs in 3% of all pregnancies and is a leading cause of maternal morbidity and mortality worldwide, where cerebral injury is among the most common complications. Further ...

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