Research at Uppsala University
History of human antibiotic use written in the oral bacteria of wild brown bears
25 August 2021. An international team of researchers used historical museum collections to study the effects of huma ...
How research can encourage us to cycle instead
19 August 2021. How do you get to work in the mornings? Transport currently accounts for 25 per cent of GHG emission ...
Philippine ethnic group has most Denisovan DNA
13 August 2021. The Philippine ethnic group Ayta Magbukon has the highest proportion of genes from our extinct relat ...
Search for research projects
Here you will find all research projects at Uppsala University funded by the main Swedish funding bodies. The search feature is based on the SweCRIS database.
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Your choice produced 10 hits
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The role of genetic and epigenetic factors in the autoimmune disease primary Sjögren’s syndrome – a step towards targeted therapies
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Research project from 2017-01-01 to 2020-12-31
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease with substantial morbidity and increased mortality in lymphoma. Although genetic factors have been described in other systemic autoimmune ...
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Discovery of functional genetic variants in systemic lupus erythematosus (SLE)
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Research project from 2015-01-01 to 2017-12-31
The aim of the project is to identify functional genetic variants in SLE. In the first part of the project we will identify previously unknown genetic variants by comparing DNA samples from SLE patients ...
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Disease mechanisms and patient stratification towards new therapies in systemic inflammatory autoimmune diseases
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Research project from 2019-01-01 to 2022-12-31
Systemic inflammatory autoimmune diseases (SIADs) are a heterogeneous group of inflammatory diseases with involvement of multiple organs. Three SIADs are systemic lupus erythematosus (SLE), primary Sjögrens ...
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Disease mechanisms in autoimmune rheumatic diseases with an interferon signature
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Research project from 2014-01-01 to 2018-12-31
A prominent feature in a number of rheumatic diseases is an increased expression in blood and tissue cells of type I interferon regulated genes (an IFN signature), which activates both the innate and adaptive ...
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Functional and prognostic impact of immune complexes and immune complex-associated autoantibodies in rheumatic diseases
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Research project from 2014-01-01 to 2016-12-31
OBJECTIVE: To study immune complex (IC)-mediated mechanisms in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), with emphasis on how IC and IC-associated autoantibodies regulate production ...
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Genetic variation and single-cell gene expression profiles in systemic lupus erythematosus (SLE)
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Research project from 2018-01-01 to 2020-12-31
In the project we will identify rare functional genetic variants in systemic lupus erythematosus (SLE). We will search for unknown rare genetic variants in Swedish patients with SLE patients by comparing ...
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How immune complexes and associated autoantibodies determine clinical phenotypes in rheumatic diseases
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Research project from 2020-01-01 to 2022-12-31
In this four-year project we will expand, develop and refine the way autoimmune serology is used to characterize and understand the pathogenetic mechanisms leading to individual clinical phenotypes of ...
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Mucosal breaks in the initiation and progression of rheumatoid arthritis
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Research project from 2020-07-01 to 2023-06-30
Rheumatoid arthritis (RA) is an autoimmune disease of the synovial joints that affects ~1% of the world population. Multiple “mucosal” risk factors are associated with the development of RA, including ...
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Nordic Symposium on Metabolic Disorders (NSMD) An interdisciplinary preclinical conference within metabolic disorders - From obesity and diabetes to development of atherosclerosis -
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Research project from 2011-07-01 to 2011-12-31
Today the metabolic syndrome is a global epidemic, driven in part by an increasing incidence of obesity in the society. A direct consequence of obesity and diabetes are major problems with the heart and ...
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Strategies to control thromboinflammation in therapeutic medicine with focus on transplantation
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Research project from 2013-01-01 to 2016-12-31
The present application focuses on the overall crosstalk during thromboinflammation in transplantation, which include the instant blood-mediated inflammatory reaction (IBMIR) in cell- and cell cluster-transplantation ...
Research spotlight: The coronavirus
New method for discovery of antiviral drugs
2 August 2021. The current COVID-19 pandemic has highlighted the need for methods to identify new or repurposed dru ...
Helpline important for older people during the pandemic
8 July 2021. For many older individuals, the COVID-19 pandemic has resulted in the loss of daily anonymous contac ...
The national COVID-19 Data Portal turns one year old
3 June 2021. The national Swedish COVID-19 Data Portal was launched one year ago to support researchers in utilis ...
Lectures
Uppsala University’s researchers share their knowledge in public lectures. Every year, the University is visited by leading researchers and influential people from around the world. At Uppsala University, you can hear Nobel laureates, researchers, authors, politicians and many others give lectures. Here we present some of the most prominent, annually occurring lectures at Uppsala University.