Entry requirements

At least two years of basic courses in Natural Sciences, equivalent to 50 points/75 ECTS credits in Biology and 20 points/30 ECTS credits in Chemistry. Biology courses should include Cell Biology, Genetics and Gene Technology, Structure and Physiology of Organisms, and Ecology. Alternatively, one year of Chemistry together with 20 points/30 ECTS credits in Biology including Structure and Physiology of Organisms and Genetics and Gene Technology.

Aims

The course is intended to provide knowledge of toxicologic methodology, knowledge of metabolism and effects of xenobiotics in animals, an overview of genetic toxicology and methods used to detect genotoxic damages on cells, organisms and populations and a platform for further studies and occupational activities.

Content

General toxicology: Toxicokinetics (uptake by different routes, distribution, metabolism, excretion, computer simulation of drug disposition using mathematical models) toxicologic methodology, toxicity testing, mechanisms of toxicity, drugs used in society, ecotoxicology, animal- and plant toxins, food toxicology and ecotoxicology. Genetic toxicology: Damages on the genetic material causing hereditary diseases and can-cer. Factors contributing to genotoxic damages. Laboratory tests for detecting mutations, structural and numerical chromosome aberrations. Organisation of test programs. Interpretation of test protocol. Risk assessment.

Instruction

Lectures, group instructions, seminars, and laboratory work. Attendance in the laboratory work and connected lessons is compulsory. The course may be taught in English.

Assessment

Examination is arranged during and at the end of the course. A passing grade for the entire course requires passing grades for the laboratory work and seminars.