Entry requirements

Bachelor's degree and Synthetic organic chemistry I, 7.5 credits.

Learning outcomes

After completion of the course the student should be able to:

- Use the knowledge from earlier courses to carry out multistep synthesis.

- Identify and analyse possible routes to a specific target molecule by means of retrosynthetic analysis.

- Identify and explain stereochemical terms such as, chirality, stereoisomer and stereoselectivity.

- Describe and identify methods for stereoselective synthesis of chiral compounds.

- Name and explain the fundamental reactions in organometallic chemistry (i.e. oxidative addition, transmetallation, ligand substitution).

- Apply organometallic reactions in organic synthesis.

- Use advanced methods for the selective preparation of compounds with complicated structures.

- Plan and dimension laboratory equipment for varios types of reactions.

- Improve her/his skills in oral and written communication

Content

Organometalic chemistry and its use in asymmetric catalysis. Chiral material and reagents. Chiral auxiliaries and enzyme catalysis. Determination of optical purity with aid of polarometry, chromatography, and NMR spectroscopy. Subject-integrated training in communication skills with feedback and self-evaluation.

Instruction

Lectures, seminars, and laboratory work. Exercises in oral and written presentation. Laboratory work and related oral presentation are mandatory.

Assessment

Written examination is arranged at the end of the course. The laboratory work must also be passed. The written examination corresponds to 2.5 credits. The laboratory exercises including written and oral presentations are valued as 5 credits.

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