Drug Formulation and Drug Delivery

Entry requirements

For search within: - the Master of Science Programme in Pharmacy the student should have at least 150 credits (100 credit points) including 60 credits (40 credit points) pharmacy including programme course in pharmaceutics and have followed all earlier courses within the programme. - the Bachelor of Science Programme in Pharmacy the student should have 120 credits (80 credit points) of which 60 credits (40 credit points) pharmacy including programme course in pharmaceutics and pharmaceutical physical chemistry and have followed all earlier courses within the programme. Qualified to single subject course are those that have undergraduate degree 120 credit points/180 credits, of which knowledge equivalent 40 credit points/60 credits pharmacy including basic education in pharmaceutics Other education is tested individually. Proficiency in Swedish and English equivalent to the general entry requirements for first-cycle (Bachelor's level) studies.

Learning outcomes

The students should on completion of the course: - be able to account for characterisation methods for the solid-phase structure, size, form, porosity and pore structure of particles - be able to account for methods for characterisation of the mechanical properties of powder materials and compression properties - be able to design system for controlled/optimised releasement and absorption of drugs - be able to design stable and optimised formulations of protein-targeted drug - having developed its ability to written scientific presentation

Content

The course is based on basic knowledge within the pharmaceutics and broadens and deepen the knowledge regarding formulation and production especially of solid preparations in aim to prepare the students for experimental scientific work and industrial pharmaceutical activities within this topic of pharmaceutics. In the course, the following subject matter is treated: Characterisation of the physical properties of solid material: Solid-state analysis, particle size analysis and particle statistics, form analysis, form factors, surface and pore-size analysis, analysis of mechanical properties and transmission at and modelling of the compression process. Formulation principles of controlled/optimised releasement and absorption of drugs: Systems for nasal, pulmonary and cutaneous drug administration and basic physiological aspects for pharmaceutical formulation. Formulation, stabilisation and lyophilisation of protein-targeted drugs and optimised administration of these.

Instruction

Teaching is given in the form of lectures and seminars. Furthermore, literary work and study visit are carried out. Compulsory parts of the course: Course introduction, study visits and literary work.

Assessment

Written examination is arranged at the end of the course. To pass the course is required apart from passed examination (examination code), passed results of literary work and participation in study visit (examination code). Opportunity to supplement failed compulsory parts can be given when the course is offered again. Each student has the right to in all six examinations i.e. one examination and five re-examinations.