Chemical Libraries and Efficient Synthesis

15 credits

Syllabus, Master's level, 1KB455

Education cycle
Second cycle
Main field(s) of study and in-depth level
Chemistry A1N
Grading system
Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
Finalised by
The Faculty Board of Science and Technology, 30 August 2018
Responsible department
Department of Chemistry - BMC

Entry requirements

120 credits with 60 credits in chemistry. Proficiency in English equivalent to the Swedish upper secondary course English 6.

Learning outcomes

On completion of the course, the student should be able to:

  • Present and discuss advanced methods in organic synthesis
  • Find relevant information from the literature by database searching
  • Apply various synthesis tools to organic compounds with low molecular weight.
  • Describe and plan DOS (diversity-oriented synthesis)
  • Present, discuss, plan and execute the construction and evaluation of a low-molecular-weight compound library.


Tools for synthesis planning, such as retrosynthesis, DOS and high-throughput strategies and their application in organic synthesis. Reactivity and selectivity in organic-chemical transformations, and their importance in synthesis planning.

Individual design project, which includes the planning of the synthesis, literature search, a presentation, as well as experimental work to prepare the suggested molecules.

Training in communication skills with written report, oral presentation, feed-back and opposition.


The teaching will be conducted by lectures, and practical work in the laboratory and theoretical exercises and projects. A significant part of the course takes place in the form of projects, where students work both individually and in groups.


A written exam will be given in the end of the course (10 credits). Reports are assessed by written and oral presentation with opposition. The mandatory exercises and reports correspond to 5 credits. The final grade is based on both the written exam and the mandatory exercises.

If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the disability coordinator of the university.