General provisions

The course is a part of the following programme:

The Medicine programme, 330 credits

Semester 2

Entry requirements

For admission to a new term, passed compulsory events are required from previous terms and all examinations, except one from the nearest previous term, must be passed. After interruption of studies, it is required that all courses from the previous terms are passed.

The education follows a course of studies, which implies that the courses should be taken in an established order.

Learning outcomes

The course should give the student detailed knowledge in cell biology, molecular biology, genetics, tissue biology, reproductive biology and embryology.

COURSE AIMS

After the course, the student should:

- be able to account for structure, organisation and function of chromosomes, genes, DNA, RNA and proteins.

- be able to account for structure and function of cell organelles

- understand how calcium levels, receptors and intracellular signal transduction control gene expression

- be able to describe DNA replication, the cell cycle and apoptosis/necrosis, and how these processes are governed

- be able to describe structure and function of the extracellular matrix, cell contacts and adhesion receptors

- be able to describe the histology and function of the urinary tract and female and male genital systems

- be able to describe meiosis, fertilisation and the properties and functions of somatic and embryonic stem cells

- be able to describe the structure, development and function of the placenta; be familiar with pathological conditions in placenta at a general level

- be able to describe the development of the embryo and the foetus

- be able to describe the fundamental principles of teratology

- be able to describe principles of inheritance and the importance of genetic variation at individual level and population level

- be able to describe origin and consequences of chromosomal anomalies

- be familiar with methods and principles of clinical genetic diagnostics, cancer cytogenetics, prenatal diagnosis and presymptomatic diagnostics

- know the organisation of the human genome and mechanisms that influence the evolution of the genome.

Content

From gene to protein, basic cell biology, secretion, the calcium metabolism, intracellular signalling, gene expression, mitosis, meiosis, apoptosis, genetic fundamental concepts, angiogenesis, cancer and tissue biology of the cell, reproduction, embryonic stem cells and embryology and teratology

Instruction

The course is given in the form of case-based group tuition, seminars, lectures, laboratory sessions, demonstrations, computer exercises and microscopy exercises.

Assessment

For regulatory framework about absence from compulsory events and rules for participation in examination, see programme syllabus in the students' guide.

Students who have not passed the examination have a right to attend 4 additional examinations (i.e. 5 examinations in total). If special circumstances apply, the programme committee may admit additional examinations. Every time the student participates in an examination counts, i.e. also submission of a so called blank exam. Submission of so called blank exam is counted as an examination. The student has right on request to change examiner after 2 failed examinations.