Institutionen för farmaci

Analysis of time-to-positivity data in tuberculosis treatment studies: Identifying a new limit of quantification

Dufault, Suzanne M.; Davies, Geraint R.; Svensson, Elin M.; Sloan, Derek J. et al.

Ingår i International Journal of Antimicrobial Agents, 2025

• DOI för Analysis of time-to-positivity data in tuberculosis treatment studies: Identifying a new limit of quantification
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Cardiovascular events following coronavirus disease 2019 vaccination in adults - a nationwide Swedish study.

Xu, Yiyi; Li, Huiqi; Santosa, Ailiana; Wettermark, Björn et al.

Ingår i European Heart Journal, s. 147-157, 2025

• DOI för Cardiovascular events following coronavirus disease 2019 vaccination in adults - a nationwide Swedish study.

Ceftazidime-avibactam (CAZ-AVI) pharmacokinetics in critically ill patients undergoing continuous venovenous hemodiafiltration (CVVHDF)

O'Jeanson, Amaury; Ioannidis, Konstantinos; Nielsen, Elisabet I.; Galani, Lamprini et al.

Ingår i International Journal of Antimicrobial Agents, 2025

• DOI för Ceftazidime-avibactam (CAZ-AVI) pharmacokinetics in critically ill patients undergoing continuous venovenous hemodiafiltration (CVVHDF)
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Comparison of the power and type 1 error of total score models for drug effect detection in clinical trials

Haem, Elham; Karlsson, Mats O.; Ueckert, Sebastian

Ingår i Journal of Pharmacokinetics and Pharmacodynamics, 2025

• DOI för Comparison of the power and type 1 error of total score models for drug effect detection in clinical trials
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Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices.

Schouten, Wietse M; Van Bocxlaer, Katrien; Rosing, Hilde; Huitema, Alwin D R et al.

Ingår i Journal of chromatography. B, s. 124377, 2025

• DOI för Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices.

Drug utilization among young adults with atopic dermatitis: Influence of sex, socio-economic status and disease severity

Lindström Carmanius, Penny; Lundin, S.; Ödling, M.; Kimland, E. et al.

Ingår i Journal of the European Academy of Dermatology and Venereology, s. 145-153, 2025

• DOI för Drug utilization among young adults with atopic dermatitis: Influence of sex, socio-economic status and disease severity
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Have People Treated With Antihypertensives Been Diagnosed With Hypertension?: A Cross-Sectional Study in Stockholm, Sweden

Treciokiene, Indre; Forslund, Tomas; Kahan, Thomas; Taxis, Katja et al.

Ingår i Pharmacoepidemiology and Drug Safety, 2025

• DOI för Have People Treated With Antihypertensives Been Diagnosed With Hypertension?: A Cross-Sectional Study in Stockholm, Sweden
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Healthcare provision for displaced people in transit: Analyses of routinely collected data from INTERSOS clinics at the Ukrainian border with Moldova and Poland

Aljadeeah, Saleh; Hosseinalipour, Seyed-Moeen; Khanyk, Nataliia; Szocs, Eszter et al.

Ingår i Journal of Migration and Health, 2025

• DOI för Healthcare provision for displaced people in transit: Analyses of routinely collected data from INTERSOS clinics at the Ukrainian border with Moldova and Poland
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Identifying critical elements in using question prompt lists at the pharmacy counter to induce patient activation: using principles of conversation analysis

Svensberg, Karin; Kaae, Susanne; Broch Mottelson, Nanna; Ljungberg Persson, Christina

Ingår i Research in Social and Administrative Pharmacy, s. 74-84, 2025

• DOI för Identifying critical elements in using question prompt lists at the pharmacy counter to induce patient activation: using principles of conversation analysis
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Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions

Alhalaweh, Amjad; El Sayed, Mira; Kovac, Lucia; Bergström, Christel A.S.

Ingår i Journal of Pharmaceutical Sciences, s. 458-467, 2025

• DOI för Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions
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Initiation of Anticoagulants During the COVID-19 Pandemic in Sweden: An Interrupted Time Series Analysis

Samuelsen, Per-Jostein; Wettermark, Björn; Nyberg, Fredrik; Hajiebrahimi, Mohammadhossein

Ingår i Basic & Clinical Pharmacology & Toxicology, 2025

• DOI för Initiation of Anticoagulants During the COVID-19 Pandemic in Sweden: An Interrupted Time Series Analysis
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Integrated modeling of biomarkers, survival and safety in clinical oncology drug development

Liu, Han; Ibrahim, Eman I.K.; Centanni, Maddalena; Sarr, Céline et al.

Ingår i Advanced Drug Delivery Reviews, 2025

• DOI för Integrated modeling of biomarkers, survival and safety in clinical oncology drug development
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Leadership and mentorship of Professor Lynne S. Taylor: A personal account from former mentees

Alhalaweh, Amjad; Indulkar, Anura S.; Mosquera-Giraldo, Laura I.; Purohit, Hitesh S. et al.

Ingår i Journal of Pharmaceutical Sciences, s. 265-268, 2025

• DOI för Leadership and mentorship of Professor Lynne S. Taylor: A personal account from former mentees

Leveraging digital medication adherence technologies to enhance sustainability of European health systems: ENABLE's key recommendations

van Boven, Job F. M.; Dima, Alexandra L.; Wettermark, Björn; Potocnjak, Ines et al.

Ingår i The Lancet Regional Health, 2025

• DOI för Leveraging digital medication adherence technologies to enhance sustainability of European health systems: ENABLE's key recommendations

Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

He, Xiguo; Karlsson, Philip; Xiong, Ruisheng; Moodie, Lindon W. K. et al.

Ingår i Journal of Colloid and Interface Science, s. 287-300, 2025

• DOI för Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
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Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Lundquist, Patrik; Hagforsen, Eva; Wagner, Michael; Alimohammadi, Mohammad et al.

Ingår i Biochimica et Biophysica Acta - Molecular Basis of Disease, 2025

• DOI för Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
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Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model.

Wilske, Frida; Eriksson, Olof; Amini, Rose-Marie; Estrada, Sergio et al.

Ingår i Intensive care medicine experimental, s. 14, 2025

• DOI för Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model.

Sociodemographic characteristics and health status of women with breast cancer and COVID 19 diagnosis by menopausal status a cross sectional study

Hajiebrahimi, Mohammadhossein; Shihan, Hussam; Bratt, Ola; Li, Huiqi et al.

Ingår i Scientific Reports, 2025

• DOI för Sociodemographic characteristics and health status of women with breast cancer and COVID 19 diagnosis by menopausal status a cross sectional study
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The challenge to identify sensitive safety biomarkers of peripheral neurotoxicity in the rat: A collaborative effort across industry and academia (IMI NeuroDeRisk project)

Micheli, Laura; Balayssac, David; Busserolles, Jérôme; Dalbos, Cristelle et al.

Ingår i Toxicology, 2025

• DOI för The challenge to identify sensitive safety biomarkers of peripheral neurotoxicity in the rat: A collaborative effort across industry and academia (IMI NeuroDeRisk project)
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A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice

Mebrahtu, Aman; Laurén, Ida; Veerman, Rosanne; Güclüler Akpinar, Gözde et al.

Ingår i Nature Communications, 2024

• DOI för A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice
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A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils

Petersen, Inga; Godec, Ana; Ranjbarian, Farahnaz; Hofer, Anders et al.

Ingår i PLOS ONE, 2024

• DOI för A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils
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A Cross-Sectional Study Identifying Medication Adherence Technologies (MATech) in Sweden Using Behavior Change Techniques

Ekenberg, Marie; Landin, Fanny; Wettermark, Björn

Ingår i Patient Preference and Adherence, s. 2281-2293, 2024

• DOI för A Cross-Sectional Study Identifying Medication Adherence Technologies (MATech) in Sweden Using Behavior Change Techniques
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A fully automatic tool for development of population pharmacokinetic models

Chen, Xiaomei; Nordgren, Rikard; Belin, Stella; Hamdan, Alzahra et al.

Ingår i CPT, s. 1784-1797, 2024

• DOI för A fully automatic tool for development of population pharmacokinetic models
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A loading dose of clofazimine to rapidly achieve steady-state-like concentrations in patients with nontuberculous mycobacterial disease

Stemkens, Ralf; Lemson, Arthur; Koele, Simon E.; Svensson, Elin M. et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 3100-3108, 2024

• DOI för A loading dose of clofazimine to rapidly achieve steady-state-like concentrations in patients with nontuberculous mycobacterial disease
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A pharmacometric multistate model for predicting long-term treatment outcomes of patients with pulmonary TB

Lin, Yu-Jou; Zou, Yuanxi; Karlsson, Mats O.; Svensson, Elin

Ingår i Journal of Antimicrobial Chemotherapy, s. 2561-2569, 2024

• DOI för A pharmacometric multistate model for predicting long-term treatment outcomes of patients with pulmonary TB

A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro

Petersen, Inga; Morrison, Jamie I.; Petrovic, Alex; Babic, Neira et al.

Ingår i Scientific Reports, 2024

• DOI för A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro

Active CNS delivery of oxycodone in healthy and endotoxemic pigs

Bällgren, Frida; Bergfast, Tilda; Ginosyan, Aghavni; Mahajan, Jessica et al.

Ingår i Fluids and Barriers of the CNS, 2024

• DOI för Active CNS delivery of oxycodone in healthy and endotoxemic pigs
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Advancing opioid stewardship in low-middle-income countries: challenges and opportunities

Jadhari, Rojita; Pathak, Nabin; Shrestha, Rajeev; Shrestha, Sunil et al.

Ingår i JOURNAL OF PHARMACEUTICAL POLICY AND PRACTICE, 2024

• DOI för Advancing opioid stewardship in low-middle-income countries: challenges and opportunities
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AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1

Díaz-Holguin, Alejandro; Saarinen, Marcus; Vo, Duc Duy; Sturchio, Andrea et al.

Ingår i Science Advances, 2024

• DOI för AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1
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Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Pagnon de la Vega, María; Syvänen, Stina; Giedraitis, Vilmantas; Hooley, Monique et al.

Ingår i Acta neuropathologica communications, 2024

• DOI för Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion
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Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches

Zhuo, Xuezhi; Foderà, Vito; Larsson, Per; Schaal, Zarah et al.

Ingår i European Journal of Pharmaceutical Sciences, 2024

• DOI för Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches
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Analysis of the contributing role of drug transport across biological barriers in the development and treatment of chemotherapy-induced peripheral neuropathy

Hu, Yang; Girdenyte, Milda; Roest, Lieke; Liukkonen, Iida et al.

Ingår i Fluids and Barriers of the CNS, 2024

• DOI för Analysis of the contributing role of drug transport across biological barriers in the development and treatment of chemotherapy-induced peripheral neuropathy
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Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Huseby, Douglas L.; Cao, Sha; Zamaratski, Edouard; Sooriyaarachchi, Sanjeewani et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI för Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
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Assessment of enhancing curcumin's solubility versus uptake on its anti-cancer efficacy

Rawas-Qalaji, Mutasem; Jagal, Jayalakshmi; Sadik, Sefeera; Said, Zafar et al.

Ingår i Colloids and Surfaces B, 2024

• DOI för Assessment of enhancing curcumin's solubility versus uptake on its anti-cancer efficacy

Barriers and Unmet Educational Needs Regarding Implementation of Medication Adherence Management Across Europe: Insights from COST Action ENABLE

Hafez, Gaye; Aarnio, Emma; Mucherino, Sara; Kamusheva, Maria et al.

Ingår i Journal of general internal medicine, s. 2917-2926, 2024

• DOI för Barriers and Unmet Educational Needs Regarding Implementation of Medication Adherence Management Across Europe: Insights from COST Action ENABLE
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Benefits of combining supersaturating and solubilizing formulations - Is two better than one?

Alvebratt, Caroline; Karlén, Filip; Åhlén, Michelle; Edueng, Khadijah et al.

Ingår i International Journal of Pharmaceutics, 2024

• DOI för Benefits of combining supersaturating and solubilizing formulations - Is two better than one?

Bridging responses to a human telomerase reverse transcriptase-based peptide cancer vaccine candidate in a mechanism-based model

Ibrahim, Eman I. K.; Ellingsen, Espen B.; Mangsbo, Sara M.; Friberg, Lena

Ingår i International Immunopharmacology, 2024

• DOI för Bridging responses to a human telomerase reverse transcriptase-based peptide cancer vaccine candidate in a mechanism-based model
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Characterization of anti-drug antibody dynamics using a bivariate mixed hidden-markov model by nonlinear-mixed effects approach

Brekkan, Ari; Lledo-Garcia, Rocio; Lacroix, Brigitte; Jonsson, Siv et al.

Ingår i Journal of Pharmacokinetics and Pharmacodynamics, s. 65-75, 2024

• DOI för Characterization of anti-drug antibody dynamics using a bivariate mixed hidden-markov model by nonlinear-mixed effects approach
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Clofazimine as a substitute for rifampicin improves efficacy of Mycobacterium avium pulmonary disease treatment in the hollow-fiber model

Salillas, Sandra; Raaijmakers, Jelmer; Aarnoutse, Rob E.; Svensson, Elin et al.

Ingår i Antimicrobial Agents and Chemotherapy, 2024

• DOI för Clofazimine as a substitute for rifampicin improves efficacy of Mycobacterium avium pulmonary disease treatment in the hollow-fiber model
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Combining mathematical modeling, in vitro data and clinical target expression to support bispecific antibody binding affinity selection: a case example with FAP-4-1BBL

Sanchez, Javier; Claus, Christina; McIntyre, Christine; Tanos, Tamara et al.

Ingår i Frontiers in Pharmacology, 2024

• DOI för Combining mathematical modeling, in vitro data and clinical target expression to support bispecific antibody binding affinity selection: a case example with FAP-4-1BBL
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Comparison of Two Methods for Determining Item Characteristic Functions and Latent Variable Time-Course for Pharmacometric Item Response Models

Arrington, Leticia; Karlsson, Mats

Ingår i AAPS Journal, 2024

• DOI för Comparison of Two Methods for Determining Item Characteristic Functions and Latent Variable Time-Course for Pharmacometric Item Response Models
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Conjugated hyperbilirubinemia associated with accidental rifapentine overdose

Yohane, M.; Naufal, F.; Endoza-Ticona, A. M.; Svensson, Elin M. et al.

Ingår i The International Journal of Tuberculosis and Lung Disease, s. 354-356, 2024

• DOI för Conjugated hyperbilirubinemia associated with accidental rifapentine overdose

Covariate modeling in pharmacometrics: General points for consideration

Sanghavi, Kinjal; Ribbing, Jakob; Rogers, James A.; Ahmed, Mariam A. et al.

Ingår i CPT, s. 710-728, 2024

• DOI för Covariate modeling in pharmacometrics: General points for consideration
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Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Soukarieh, Fadi; Mashabi, Alaa; Richardson, William; Oton, Eduard Vico et al.

Ingår i Journal of Medicinal Chemistry, s. 1008-1023, 2024

• DOI för Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections
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Determining tissue distribution of the oral antileishmanial agent miltefosine: a physiologically-based pharmacokinetic modeling approach

Ramisetty, Bhargavi Srija; Yang, Sihyung; Dorlo, Thomas P.C.; Wang, Michael Zhuo

Ingår i Antimicrobial Agents and Chemotherapy, 2024

• DOI för Determining tissue distribution of the oral antileishmanial agent miltefosine: a physiologically-based pharmacokinetic modeling approach

Development and characterization of solid lipid-based formulations (sLBFs) of ritonavir utilizing a lipolysis and permeation assay

Schulzen, Arne; Andreadis, Ioannis I.; Bergström, Christel A. S.; Quodbach, Julian

Ingår i European Journal of Pharmaceutical Sciences, 2024

• DOI för Development and characterization of solid lipid-based formulations (sLBFs) of ritonavir utilizing a lipolysis and permeation assay
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Development and comparison of model-integrated evidence approaches for bioequivalence studies with pharmacokinetic end points

Chen, Xiaomei; Bjugård Nyberg, Henrik; Donnelly, Mark; Zhao, Liang et al.

Ingår i CPT, s. 1734-1747, 2024

• DOI för Development and comparison of model-integrated evidence approaches for bioequivalence studies with pharmacokinetic end points
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Development and validation of an ultra-performance liquid chromatography-tandem mass spectrometry method for the quantification of the antimalarial drug pyronaridine in human whole blood

Schouten, Wietse M.; Roseboom, Ignace C.; Lucas, Luc; Tshiongo, Japhet Kabalu et al.

Ingår i Journal of Pharmaceutical and Biomedical Analysis, 2024

• DOI för Development and validation of an ultra-performance liquid chromatography-tandem mass spectrometry method for the quantification of the antimalarial drug pyronaridine in human whole blood
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Development of a canine artificial colonic mucus model for drug diffusion studies

Barmpatsalou, Vicky; Tjakra, Marco; Li, Lingxiao; Dubbelboer, Ilse R. et al.

Ingår i European Journal of Pharmaceutical Sciences, 2024

• DOI för Development of a canine artificial colonic mucus model for drug diffusion studies
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Digoxin Pharmacokinetics in Patients with Obesity Before and After a Gastric Bypass or a Strict Diet Compared with Normal Weight Individuals

Kvitne, Kine Eide; Hovd, Markus; Johnson, Line Kristin; Wegler, Christine et al.

Ingår i Clinical Pharmacokinetics, s. 109-120, 2024

• DOI för Digoxin Pharmacokinetics in Patients with Obesity Before and After a Gastric Bypass or a Strict Diet Compared with Normal Weight Individuals
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